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6DTI
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BU of 6dti by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an unmodifed anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin
Descriptor: 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Cantara, W.A, DeMirci, H, Agris, P.F.
Deposit date:2018-06-16
Release date:2019-04-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.54 Å)
Cite:A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.
J.Mol.Biol., 432, 2020
1FEQ
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BU of 1feq by Molmil
NMR SOLUTION STRUCTURE OF THE ANTICODON OF TRNA(LYS3) WITH T6A MODIFICATION AT POSITION 37
Descriptor: 5'-R(*GP*CP*AP*GP*AP*CP*UP*UP*UP*UP*(T6A)P*AP*UP*CP*UP*GP*C)-3'
Authors:Stuart, J.W, Gdaniec, Z, Guenther, R.H, Marszalek, M, Sochacka, E, Malkiewicz, A, Agris, P.F.
Deposit date:2000-07-21
Release date:2000-11-22
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Functional anticodon architecture of human tRNALys3 includes disruption of intraloop hydrogen bonding by the naturally occurring amino acid modification, t6A.
Biochemistry, 39, 2000
229D
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BU of 229d by Molmil
DNA ANALOG OF YEAST TRANSFER RNA PHE ANTICODON DOMAIN WITH MODIFIED BASES 5-METHYL CYTOSINE AND 1-METHYL GUANINE
Descriptor: DNA (5'-D(*CP*CP*AP*GP*AP*CP*(UMP)P*GP*AP*AP*(MG1)P*AP*(UMP)P*(5CM)P*(UMP)P*GP*G)-3')
Authors:Basti, M.M, Stuart, J.W, Lam, A.T, Guenther, R, Agris, P.F.
Deposit date:1995-08-16
Release date:1995-12-07
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Design, biological activity and NMR-solution structure of a DNA analogue of yeast tRNA(Phe) anticodon domain.
Nat.Struct.Biol., 3, 1996
6MPI
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BU of 6mpi by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGU-codon in the A-site and paromomycin
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Cantara, W.A, DeMirci, H, Agris, P.F.
Deposit date:2018-10-07
Release date:2019-04-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.
J.Mol.Biol., 432, 2020
6MKN
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BU of 6mkn by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Cantara, W.A, DeMirci, H, Agris, P.F.
Deposit date:2018-09-25
Release date:2019-04-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.46 Å)
Cite:A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.
J.Mol.Biol., 432, 2020
6MPF
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BU of 6mpf by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGC-codon in the A-site and paromomycin
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Cantara, W.A, DeMirci, H, Agris, P.F.
Deposit date:2018-10-05
Release date:2019-04-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.
J.Mol.Biol., 432, 2020
1XMO
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BU of 1xmo by Molmil
Crystal Structure of mnm5U34t6A37-tRNALysUUU Complexed with AAG-mRNA in the Decoding Center
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Murphy, F.V, Ramakrishnan, V, Malkiewicz, A, Agris, P.F.
Deposit date:2004-10-04
Release date:2004-12-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:The role of modifications in codon discrimination by tRNA(Lys)(UUU).
Nat.Struct.Mol.Biol., 11, 2004
1XMQ
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BU of 1xmq by Molmil
Crystal Structure of t6A37-ASLLysUUU AAA-mRNA Bound to the Decoding Center
Descriptor: 16s ribosomal RNA, 30S Ribosomal Protein S10, 30S Ribosomal Protein S11, ...
Authors:Murphy, F.V, Ramakrishnan, V, Malkiewicz, A, Agris, P.F.
Deposit date:2004-10-04
Release date:2004-12-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The role of modifications in codon discrimination by tRNA(Lys)(UUU).
Nat.Struct.Mol.Biol., 11, 2004
3T1Y
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BU of 3t1y by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA Lysine 3 (TRNALYS3) bound to an mRNA with an AAG-codon in the A-site and paromomycin
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Murphy, F.V, Vendeix, F.A.P, Cantara, W, Leszczynska, G, Gustilo, E.M, Sproat, B, Malkiewicz, A.A.P, Agris, P.F.
Deposit date:2011-07-22
Release date:2012-01-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism.
J.Mol.Biol., 416, 2012
3T1H
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BU of 3t1h by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA lysine 3 (tRNALys3) bound to an mRNA with an AAA-codon in the A-site and Paromomycin
Descriptor: 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Murphy, F.V, Vendeix, F.A.P, Cantara, W, Leszczynska, G, Gustilo, E.M, Sproat, B, Malkiewicz, A.A.P, Agris, P.F.
Deposit date:2011-07-21
Release date:2012-01-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism.
J.Mol.Biol., 416, 2012
4GKJ
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BU of 4gkj by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human mitochondrial anticodon stem loop (ASL) of transfer RNA Methionine (TRNAMET) bound to an mRNA with an AUG-codon in the A-site and paromomycin.
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Cantara, W.A, Murphy IV, F.V, Spears, J.L, Demirci, H, Agris, P.F.
Deposit date:2012-08-11
Release date:2013-06-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.298 Å)
Cite:Expanded use of sense codons is regulated by modified cytidines in tRNA.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GKK
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BU of 4gkk by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human mitochondrial anticodon stem loop (ASL) of transfer RNA Methionine (TRNAMET) bound to an mRNA with an AUA-codon in the A-site and paromomycin
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Cantara, W.A, Murphy IV, F.V, Spears, J.L, Demirci, H, Agris, P.F.
Deposit date:2012-08-11
Release date:2013-06-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Expanded use of sense codons is regulated by modified cytidines in tRNA.
Proc.Natl.Acad.Sci.USA, 110, 2013
1KOS
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BU of 1kos by Molmil
SOLUTION NMR STRUCTURE OF AN ANALOG OF THE YEAST TRNA PHE T STEM LOOP CONTAINING RIBOTHYMIDINE AT ITS NATURALLY OCCURRING POSITION
Descriptor: 5'-R(*CP*UP*GP*UP*GP*(5MU)P*UP*CP*GP*AP*UP*(CH)P*CP*AP*CP*AP*G)- 3'
Authors:Koshlap, K.M, Guenther, R, Sochacka, E, Malkiewicz, A, Agris, P.F.
Deposit date:1999-05-03
Release date:1999-10-22
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:A distinctive RNA fold: the solution structure of an analogue of the yeast tRNAPhe T Psi C domain.
Biochemistry, 38, 1999
1LUU
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BU of 1luu by Molmil
NMR SOLUTION STRUCTURE OF THE ANTICODON OF YEAST TRNA-PHE WITH 4 MODIFICATIONS (OMC32 OMG34 1MG37 5MC40)
Descriptor: 5'-R(*CP*CP*AP*GP*AP*(OMC)P*UP*(OMG)P*AP*AP*(1MG)P*AP*UP*(5MC)P*UP*GP*G)-3'
Authors:Stuart, J.W, Koshlap, K.M, Guenther, R.H, Agris, P.F.
Deposit date:2002-05-23
Release date:2003-09-09
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Naturally-occurring Modification Restricts the Anticodon Domain Conformational Space of tRNA(Phe).
J.Mol.Biol., 334, 2003
1LUX
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BU of 1lux by Molmil
NMR SOLUTION STRUCTURE OF THE ANTICODON OF YEAST TRNA-PHE WITH 3 MODIFICATIONS (OMC32 OMG34 M5C40)
Descriptor: 5'-R(*CP*CP*AP*GP*AP*(OMC)P*UP*(OMG)P*AP*AP*GP*AP*UP*(5MC)P*UP*GP*G)-3'
Authors:Stuart, J.W, Koshlap, K.M, Guenther, R.H, Agris, P.F.
Deposit date:2002-05-23
Release date:2003-09-09
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Naturally-occurring Modification Restricts the Anticodon Domain Conformational Space of tRNA(Phe).
J.Mol.Biol., 334, 2003
2MX1
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BU of 2mx1 by Molmil
Structure of the E. coli Threonylcarbamoyl-AMP Synthase TSAC
Descriptor: Threonylcarbamoyl-AMP synthase
Authors:Harris, K.A, Bobay, B.G, Sarachan, K.L, Sims, A.F, Bilbille, Y, Deutsch, C, Iwata-Reuyl, D, Agris, P.F.
Deposit date:2014-12-06
Release date:2015-06-17
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR-based Structural Analysis of Threonylcarbamoyl-AMP Synthase and Its Substrate Interactions.
J.Biol.Chem., 290, 2015
2UUB
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BU of 2uub by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUU-codon in the A-site and paromomycin.
Descriptor: 16S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V.
Deposit date:2007-03-01
Release date:2007-05-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism for Expanding the Decoding Capacity of Transfer Rnas by Modification of Uridines
Nat.Struct.Mol.Biol., 14, 2007
2UUA
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BU of 2uua by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUC-codon in the A-site and paromomycin.
Descriptor: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V.
Deposit date:2007-03-01
Release date:2007-05-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines.
Nat. Struct. Mol. Biol., 14, 2007
2UU9
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BU of 2uu9 by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUG-codon in the A-site and paromomycin.
Descriptor: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V.
Deposit date:2007-03-01
Release date:2007-05-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines.
Nat. Struct. Mol. Biol., 14, 2007
2UUC
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BU of 2uuc by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUA-codon in the A-site and paromomycin.
Descriptor: 16S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V.
Deposit date:2007-03-01
Release date:2007-05-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines.
Nat. Struct. Mol. Biol., 14, 2007
2JR4
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BU of 2jr4 by Molmil
NMR Solution Structure of the Anticodon of E.coli TRNA-VAL3 With no Modifications
Descriptor: 5'-R(*CP*CP*UP*CP*CP*CP*UP*UP*AP*CP*AP*AP*GP*GP*AP*GP*G)-3'
Authors:Vendeix, F.A.P, Dziergowska, A, Gustilo, E.M, Graham, W.D, Sproat, B, Malkiewicz, A, Agris, P.F.
Deposit date:2007-06-20
Release date:2007-07-24
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Anticodon domain modifications contribute order to tRNA for ribosome-mediated codon binding.
Biochemistry, 47, 2008
2JSG
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BU of 2jsg by Molmil
NMR solution structure of the anticodon of E.coli TRNA-VAL3 with 1 modification (M6A37)
Descriptor: 5'-R(*CP*CP*UP*CP*CP*CP*UP*UP*AP*CP*(6MZ)P*AP*GP*GP*AP*GP*G)-3'
Authors:Vendeix, F.A.P, Dziergowska, A, Gustilo, E.M, Graham, W.D, Sproat, B, Malkiewicz, A, Agris, P.F.
Deposit date:2007-07-04
Release date:2007-08-07
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Wobble-Position Modifications Pre-structure tRNA's Anticodon for Ribosome-Mediated Codon Binding
To be Published
2JRG
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BU of 2jrg by Molmil
NMR solution structure of the anticodon of E. coli TRNA-VAL3 with 2 modifications (cmo5U34 M6A37)
Descriptor: 5'-R(*CP*CP*UP*CP*CP*CP*UP*(CM0)P*AP*CP*(6MZ)P*AP*GP*GP*AP*GP*G)-3'
Authors:Vendeix, F.A, Dziergowska, A, Gustilo, E.M, Graham, W.D, Sproat, B, Malkiewicz, A, Agris, P.F.
Deposit date:2007-06-26
Release date:2007-07-24
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Anticodon domain modifications contribute order to tRNA for ribosome-mediated codon binding.
Biochemistry, 47, 2008
2JRQ
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BU of 2jrq by Molmil
NMR solution structure of the anticodon of E. coli TRNA-VAL3 with 1 modification (cmo5U34)
Descriptor: 5'-R(*CP*CP*UP*CP*CP*CP*UP*(CM0)P*AP*CP*AP*AP*GP*GP*AP*GP*G)-3'
Authors:Vendeix, F.A.P, Dziergowska, A, Gustilo, E.M, Graham, W.D, Sproat, B, Malkiewicz, A, Agris, P.F.
Deposit date:2007-06-28
Release date:2007-07-24
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Wobble-Position Modifications Pre-structure tRNA's Anticodon for Ribosome-Mediated Codon Binding
To be Published
2KRP
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BU of 2krp by Molmil
Solution structure of the E. coli tRNA-Arg2(acg) anticodon stem and loop
Descriptor: RNA (5'-R(*CP*UP*CP*GP*GP*CP*UP*AP*CP*GP*AP*AP*CP*CP*GP*AP*G)-3')
Authors:Bilbille, Y, Agris, P.F.
Deposit date:2009-12-22
Release date:2010-12-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the tRNA-Arg2 ASL containing the ACG anticodon
To be Published

 

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