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1YPZ
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BU of 1ypz by Molmil
Immune receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
Authors:Adams, E.J, Garcia, K.C.
Deposit date:2005-01-31
Release date:2005-04-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22.
Science, 308, 2005
5HM7
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BU of 5hm7 by Molmil
The Intracellular domain of Butyrophilin 3A1 protein
Descriptor: BETA-MERCAPTOETHANOL, Butyrophilin subfamily 3 member A1, GLYCEROL, ...
Authors:Adams, E.J, Gu, S.
Deposit date:2016-01-15
Release date:2017-07-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Phosphoantigen-induced conformational change of butyrophilin 3A1 (BTN3A1) and its implication on V gamma 9V delta 2 T cell activation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5KNM
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BU of 5knm by Molmil
Human leukocyte antigen F (HLA-F) presents peptides and regulates immunity through interactions with NK-cell receptors
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Leukocyte immunoglobulin-like receptor subfamily B member 1, ...
Authors:Dulberger, C.L, Adams, E.J.
Deposit date:2016-06-28
Release date:2017-06-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors.
Immunity, 46, 2017
5IUE
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BU of 5iue by Molmil
Human leukocyte antigen F (HLA-F) presents peptides and regulates immunity through interactions with NK-cell receptors
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Peptide LEU-ILE-LEU-ARG-TRP-GLU-GLN-ASP, ...
Authors:Dulberger, C.L, Adams, E.J.
Deposit date:2016-03-17
Release date:2017-06-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors.
Immunity, 46, 2017
1R5V
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BU of 1r5v by Molmil
Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T-cell activation
Descriptor: H-2 class II histocompatibility antigen, E-K alpha chain, MHC H2-IE-beta, ...
Authors:Krogsgaard, M, Prado, N, Adams, E.J, He, X.L, Chow, D.C, Wilson, D.B, Garcia, K.C, Davis, M.M.
Deposit date:2003-10-13
Release date:2004-02-03
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation.
Mol.Cell, 12, 2003
4EPU
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BU of 4epu by Molmil
Ang1 fibrinogen-related domain (FReD)
Descriptor: Angiopoietin-1, CALCIUM ION
Authors:Yeykal, C.C, Adams, E.J.
Deposit date:2012-04-17
Release date:2013-04-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.098 Å)
Cite:Biochemical and structural characterization of the Ang1 fibrinogen-related domain
To be Published
4EN3
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BU of 4en3 by Molmil
Crystal structure of a human Valpha24(-) NKT TCR in complex with CD1d/alpha-galactosylceramide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ...
Authors:Lopez-Sagaseta, J, Adams, E.J.
Deposit date:2012-04-12
Release date:2012-10-31
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.568 Å)
Cite:The Molecular Basis for Recognition of CD1d/alpha-Galactosylceramide by a Human Non-Valpha24 T Cell Receptor Struct. Title
Plos Biol., 10, 2012
1U3H
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BU of 1u3h by Molmil
Crystal structure of mouse TCR 172.10 complexed with MHC class II I-Au molecule at 2.4 A
Descriptor: H-2 class II histocompatibility antigen, A-U alpha chain, A-U beta chain, ...
Authors:Maynard, J, Petersson, K, Wilson, D.H, Adams, E.J, Blondelle, S.E, Boulanger, M.J, Wilson, D.B, Garcia, K.C.
Deposit date:2004-07-21
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity
Immunity, 22, 2005
6D7G
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BU of 6d7g by Molmil
Structure of 5F3 TCR in complex with HLA-A2/MART-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MART1 PEPTIDE-BETA-2-MICROGLOBULIN-HLA-A*02 CHIMERA, T-CELL RECEPTOR GAMMA VARIABLE 8,T-CELL RECEPTOR GAMMA-2 CHAIN C REGION, ...
Authors:Roy, S, Adams, E.J.
Deposit date:2018-04-24
Release date:2019-01-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Generation and molecular recognition of melanoma-associated antigen-specific human gamma delta T cells.
Sci Immunol, 3, 2018
3OV6
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BU of 3ov6 by Molmil
CD1c in complex with MPM (mannosyl-beta1-phosphomycoketide)
Descriptor: 1-O-[(S)-hydroxy{[(4S,8S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl]oxy}phosphoryl]-beta-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
Authors:Scharf, L, Li, N.S, Hawk, A.J, Garzon, D, Zhang, T, Kazen, A.R, Shah, S, Haddadian, E.J, Saghatelian, A, Faraldo-Gomez, J.D, Meredith, S.C, Piccirilli, J.A, Adams, E.J.
Deposit date:2010-09-15
Release date:2011-01-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:The 2.5 A structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation
Immunity, 33, 2010
3TYF
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BU of 3tyf by Molmil
Crystal structure of a CD1d-lysophosphatidylcholine reactive iNKT TCR
Descriptor: GLYCEROL, iNKT Cell Receptor Alpha Chain, iNKT Cell Receptor Beta Chain
Authors:Lopez-Sagaseta, J, Adams, E.J.
Deposit date:2011-09-24
Release date:2012-04-25
Method:X-RAY DIFFRACTION (2.806 Å)
Cite:Lysophospholipid presentation by CD1d and recognition by a human Natural Killer T-cell receptor.
Embo J., 31, 2012
3TZV
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BU of 3tzv by Molmil
Crystal structure of an iNKT TCR in complex with CD1d-lysophosphatidylcholine
Descriptor: (4R,7R,18E)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ...
Authors:Lopez-Sagaseta, J, Adams, E.J.
Deposit date:2011-09-27
Release date:2012-04-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.056 Å)
Cite:Lysophospholipid presentation by CD1d and recognition by a human Natural Killer T-cell receptor.
Embo J., 31, 2012
3U0P
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BU of 3u0p by Molmil
Crystal structure of human CD1d-lysophosphatidylcholine
Descriptor: (4R,7R,18E)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ...
Authors:Lopez-Sagaseta, J, Sibener, L.V, Adams, E.J.
Deposit date:2011-09-28
Release date:2012-04-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Lysophospholipid presentation by CD1d and recognition by a human Natural Killer T-cell receptor.
Embo J., 31, 2012
8G1B
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BU of 8g1b by Molmil
Crystal structure of polyreactive 2G02 human Fab
Descriptor: The heavy chain of human 2G02 Fab fragment, The light chain of human 2G02 Fab fragment
Authors:Borowska, M.T, Adams, E.J.
Deposit date:2023-02-01
Release date:2023-10-18
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Biochemical and biophysical characterization of natural polyreactivity in antibodies.
Cell Rep, 42, 2023
8G19
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BU of 8g19 by Molmil
Crystal structure of monoreactive 4C05 human Fab
Descriptor: Heavy chain of anti-influenza human 4C05 Fab fragment, Light chain of anti-influenza human 4C05 Fab fragment
Authors:Borowska, M.T, Adams, E.J.
Deposit date:2023-02-01
Release date:2023-10-18
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Biochemical and biophysical characterization of natural polyreactivity in antibodies.
Cell Rep, 42, 2023
8FZP
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BU of 8fzp by Molmil
Crystal structure of polyreactive 43G10 mouse Fab
Descriptor: 43G10 Fab heavy chain, 43G10 Fab light chain
Authors:Borowska, M.T, Adams, E.J.
Deposit date:2023-01-29
Release date:2023-10-18
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Biochemical and biophysical characterization of natural polyreactivity in antibodies.
Cell Rep, 42, 2023
8G1C
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BU of 8g1c by Molmil
Crystal structure of polyreactive 3B03 human Fab
Descriptor: Heavy chain of monoreactive 3B03 human Fab fragment, Light chain of monoreactive 3B03 human Fab fragment
Authors:Borowska, M.T, Adams, E.J.
Deposit date:2023-02-01
Release date:2023-10-18
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Biochemical and biophysical characterization of natural polyreactivity in antibodies.
Cell Rep, 42, 2023
8FZO
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BU of 8fzo by Molmil
Crystal structure of polyreactive 338E6 mouse Fab
Descriptor: 338E6 Fab heavy chain, 338E6 Fab light chain
Authors:Borowska, M.T, Adams, E.J.
Deposit date:2023-01-29
Release date:2023-10-18
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Biochemical and biophysical characterization of natural polyreactivity in antibodies.
Cell Rep, 42, 2023
4F8T
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BU of 4f8t by Molmil
Crystal Structure of the Human BTN3A3 Ectodomain
Descriptor: Butyrophilin subfamily 3 member A3
Authors:Palakodeti, A, Sandstrom, A, Sundaresan, L, Harly, C, Nedellec, S, Olive, D, Scotet, E, Bonneville, M, Adams, E.J.
Deposit date:2012-05-17
Release date:2012-08-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.382 Å)
Cite:The molecular basis for modulation of human V(gamma)9V(delta)2 T cell response by CD277/Butryophilin (BTN3A)-specific antibodies
J.Biol.Chem., 287, 2012
4F9L
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BU of 4f9l by Molmil
Crystal Structure of the Human BTN3A1 Ectodomain in Complex with the 20.1 Single Chain Antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 20.1 anti-BTN3A1 antibody fragment, Butyrophilin subfamily 3 member A1
Authors:Palakodeti, A, Sandstrom, A, Sundaresan, L, Harly, C, Nedellec, S, Olive, D, Scotet, E, Bonneville, M, Adams, E.J.
Deposit date:2012-05-18
Release date:2012-08-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.1404 Å)
Cite:The molecular basis for modulation of human V(gamma)9V(delta)2 T cell responses by CD277/Butyrophilin-3 (BTN3A)-specific antibodies
J.Biol.Chem., 287, 2012
4F80
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BU of 4f80 by Molmil
Crystal Structure of the human BTN3A1 ectodomain
Descriptor: Butyrophilin subfamily 3 member A1
Authors:Palakodeti, A, Sandstrom, A, Sundaresan, L, Harly, C, Nedellec, S, Olive, D, Scotet, E, Bonneville, M, Adams, E.J.
Deposit date:2012-05-16
Release date:2012-08-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.944 Å)
Cite:The molecular basis for modulation of human V(gamma)9V(delta)2 T cell responses by CD277/Butyrophilin-3 (BTN3A)-specific antibodies
J.Biol.Chem., 287, 2012
4F9P
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BU of 4f9p by Molmil
Crystal Structure of the Human BTN3A1 Ectodomain in Complex with the 103.2 Single Chain Antibody
Descriptor: 103.2 anti-BTN3A1 antibody fragment, Butyrophilin subfamily 3 member A1
Authors:Palakodeti, A, Sandstrom, A, Sundaresan, L, Harly, C, Nedellec, S, Olive, D, Scotet, E, Bonneville, M, Adams, E.J.
Deposit date:2012-05-19
Release date:2012-08-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.519 Å)
Cite:The molecular basis for modulation of human V(gamma)9V(delta)2 T cell responses by CD277/Butyrophilin-3 (BTN3A)-specific antibodies
J.Biol.Chem., 287, 2012
4F8Q
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BU of 4f8q by Molmil
Crystal Structure of the Human BTN3A2 Ectodomain
Descriptor: Butyrophilin subfamily 3 member A2
Authors:Palakodeti, A, Sandstrom, A, Sundaresan, L, Harly, C, Nedellec, S, Olive, D, Scotet, E, Bonneville, M, Adams, E.J.
Deposit date:2012-05-17
Release date:2012-08-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3789 Å)
Cite:The molecular basis for modulation of human V(gamma)9V(delta)2 T cell responses by CD277/Butyrophilin-3 (BTN3A)-specific antibodies
J.Biol.Chem., 287, 2012
4IIQ
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BU of 4iiq by Molmil
Crystal structure of a human MAIT TCR in complex with bovine MR1
Descriptor: Beta-2-microglobulin, MHC class I-related protein, Human Mucosal Associated Invariant T cell receptor alpha chain, ...
Authors:Lopez-Sagaseta, J, Adams, E.J.
Deposit date:2012-12-20
Release date:2013-04-24
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:The molecular basis for Mucosal-Associated Invariant T cell recognition of MR1 proteins.
Proc.Natl.Acad.Sci.USA, 110, 2013
7KPJ
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BU of 7kpj by Molmil
Crystal structure of Ruminococcus gnavus immunoglobulin binding protein in complex with 338E6 Fab
Descriptor: 338E6 Fab heavy chain, 338E6 Fab light chain kappa, CALCIUM ION, ...
Authors:Borowska, M.T, Adams, E.J.
Deposit date:2020-11-11
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The molecular characterization of antibody binding to a superantigen-like protein from a commensal microbe.
Proc.Natl.Acad.Sci.USA, 118, 2021

 

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