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Structure of human FXR in complex with MFA-1 and co-activator peptide
Descriptor:	(8alpha,10alpha,13alpha,17beta)-17-[(4-hydroxyphenyl)carbonyl]androsta-3,5-diene-3-carboxylic acid, Bile acid receptor, Nuclear receptor coactivator 1, ...
Authors:	Soisson, S.M, Parthasarathy, G, Becker, J.W.
Deposit date:	2007-11-19
Release date:	2008-03-18
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Identification of a potent synthetic FXR agonist with an unexpected mode of binding and activation. Proc.Natl.Acad.Sci.Usa, 105, 2008

CHARACTERIZATION OF THE ANTIGENIC SITES ON THE REFINED 3-ANGSTROMS RESOLUTION STRUCTURE OF MOUSE TESTICULAR LACTATE DEHYDROGENASE C4
Descriptor:	APO-LACTATE DEHYDROGENASE
Authors:	Griffith, J.P, Rossmann, M.G.
Deposit date:	1987-11-25
Release date:	1989-04-19
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.96 Å)
Cite:	Characterization of the antigenic sites on the refined 3-A resolution structure of mouse testicular lactate dehydrogenase C4. J.Biol.Chem., 262, 1987

Crystal Structure of Human PPAR-gamma Ligand Binding Domain Complexed with an Alpha-Aryloxyphenylacetic Acid Agonist
Descriptor:	(2S)-(4-ISOPROPYLPHENYL)[(2-METHYL-3-OXO-5,7-DIPROPYL-2,3-DIHYDRO-1,2-BENZISOXAZOL-6-YL)OXY]ACETATE, Peroxisome proliferator activated receptor gamma
Authors:	Shi, G.Q, Dropinski, J.F, McKeever, B.M, Adams, A.D, MacNaul, K.L, Elbrecht, A, Berger, J.P, Zhou, G, Doebber, T.W.
Deposit date:	2005-04-19
Release date:	2006-04-25
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Design and Synthesis of alpha-Aryloxyphenylacetic Acid Derivatives: A Novel Class of PPAR alpha/gamma Dual Agonists with Potent Antihyperglycemic and Lipid Modulating Activity J.Med.Chem., 48, 2005