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4J2I
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MULTIPLE CRYSTAL STRUCTURES OF AN ALL-AT DNA DODECAMER STABILIZED BY WEAK INTERACTIONS
Descriptor:5'-D(*AP*AP*TP*AP*AP*AP*TP*TP*TP*AP*TP*T)-3'
Authors:Acosta-Reyes, F.J., Subirana, J.A., Pous, J., Sanchez, R., Condom, N., Baldini, R., Malinina, L., Campos, J.L.
Deposit date:2013-02-04
Release date:2014-02-05
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Polymorphic crystal structures of an all-AT DNA dodecamer.
Biopolymers, 103, 2015
4OCD
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IN AND OUT THE MINOR GROOVE: INTERACTION OF AN AT RICH-DNA WITH THE CD27 DRUG
Descriptor:d(AAAATTTT), N1-(4,5-dihydro-1H-imidazol-2-yl)-N4-(4-((4,5-dihydro-1H-imidazol-2-yl)amino)phenyl)benzene-1,4-diamine
Authors:Acosta-Reyes, F.J., Dardonville, C., de Koning, H.P., Natto, M., Subirana, J.A., Campos, J.L.
Deposit date:2014-01-08
Release date:2014-06-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:In and out of the minor groove: interaction of an AT-rich DNA with the drug CD27
Acta Crystallogr.,Sect.D, D70, 2014
4U9M
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STRUCTURE OF THE DNA DUPLEX D(ATTAAT)2 WITH HOOGSTEEN HYDROGEN BONDS
Descriptor:DNA (5'-D(*AP*TP*TP*AP*AP*T)-3')
Authors:Acosta-Reyes, F.J., Alechaga, E., Subirana, J.A., Campos, J.L.
Deposit date:2014-08-06
Release date:2015-04-01
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Structure of the DNA Duplex d(ATTAAT)2 with Hoogsteen Hydrogen Bonds.
Plos One, 10, 2015
4QR9
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CRYSTAL STRUCTURE OF TWO HMGB1 BOX A DOMAINS COOPERATING TO UNDERWIND AND KINK A DNA
Descriptor:High mobility group protein B1, DNA (5'-D(*AP*TP*AP*TP*CP*GP*AP*TP*AP*T)-3'), MAGNESIUM ION
Authors:Sanchez-Giraldo, R., Acosta-Reyes, F.J., Malarkey, C.S., Saperas, N., Churchill, M.E.A., Campos, J.L.
Deposit date:2014-06-30
Release date:2015-07-01
Last modified:2015-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Two high-mobility group box domains act together to underwind and kink DNA.
Acta Crystallogr.,Sect.D, 71, 2015
5F9I
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CRYSTAL STRUCTURE OF RICH-AT DNA 20MER
Descriptor:DNA (5'-D(*CP*CP*AP*AP*TP*AP*AP*TP*CP*GP*CP*GP*AP*TP*TP*AP*TP*TP*GP*G)-3')
Authors:Garcia, S., Acosta-Reyes, F.J., Saperas, N., Campos, J.L.
Deposit date:2015-12-09
Release date:2016-06-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of rich-AT DNA 20mer
To Be Published
5M68
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AT-RICH DNA DODECAMER WITH EXTRA HELICAL GUANINE-NICKEL COORDINATION
Descriptor:DNA (5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*TP*TP*CP*G)-3'), NICKEL (II) ION
Authors:Campos, J.L., Saperas, N., Acosta-Reyes, F.J., Pagan, M.
Deposit date:2016-10-24
Release date:2017-11-15
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:AT-rich DNA with extra helical guanine-nickel coordination
To Be Published
4HW1
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MULTIPLE CRYSTAL STRUCTURES OF AN ALL-AT DNA DODECAMER STABILIZED BY WEAK INTERACTIONS.
Descriptor:DNA (5'-D(*AP*AP*TP*AP*AP*AP*TP*TP*TP*AP*TP*T)-3'), MAGNESIUM ION
Authors:Acosta-Reyes, F., Subirana, J.A., Pous, J., Condom, N., Malinina, L., Campos, J.L.
Deposit date:2012-11-07
Release date:2013-11-20
Last modified:2015-02-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Polymorphic crystal structures of an all-AT DNA dodecamer.
Biopolymers, 103, 2015
3UXW
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CRYSTAL STRUCTURES OF AN A-T-HOOK/DNA COMPLEX
Descriptor:dodecamer DNA, A-T hook peptide
Authors:Fonfria-Subiros, E., Acosta-Reyes, F.J., Saperas, N., Pous, J., Subirana, J.A., Campos, J.L.
Deposit date:2011-12-05
Release date:2012-05-23
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of a complex of DNA with one AT-hook of HMGA1.
Plos One, 7, 2012
5LIT
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STRUCTURE OF THE DNA DUPLEX D(AAATTT)2 WITH THE POTENTIAL ANTIPARASITIC DRUG 6XV AT 1.25 A RESOLUTION
Descriptor:DNA (5'-D(*AP*AP*AP*TP*TP*T)-3'), 4-((4,5-dihydro-1H-imidazol-2-yl)amino)-N-(4-((4,5-dihydro-1H-imidazol-2-yl)amino)phenyl)benzamide dihydrochloride, MAGNESIUM ION
Authors:Millan, C.R., Dardonville, C., de Koning, H.P., Saperas, N., Lourdes Campos, J.
Deposit date:2016-07-15
Release date:2017-06-14
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Functional and structural analysis of AT-specific minor groove binders that disrupt DNA-protein interactions and cause disintegration of the Trypanosoma brucei kinetoplast.
Nucleic Acids Res., 45, 2017
6GIM
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STRUCTURE OF THE DNA DUPLEX D(AAATTT)2 WITH [N-(3-CHLORO-4-((4,5-DIHYDRO-1H-IMIDAZOL-2-YL)AMINO)PHENYL)-4-((4,5-DIHYDRO-1H-IMIDAZOL-2- YL)AMINO)BENZAMIDE] - (DRUG JNI18)
Descriptor:DNA (5'-D(*AP*AP*AP*TP*TP*T)-3'), [4-[(3-chloranyl-4-imidazolidin-2-ylideneazaniumyl-phenyl)carbamoyl]phenyl]-imidazolidin-2-ylidene-azanium, MAGNESIUM ION
Authors:Millan, C.R., Dardonvile, C., de Koning, H.P., Saperas, N., Campos, J.L.
Deposit date:2018-05-14
Release date:2018-08-08
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Functional and structural analysis of AT-specific minor groove binders that disrupt DNA-protein interactions and cause disintegration of the Trypanosoma brucei kinetoplast.
Nucleic Acids Res., 45, 2017