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2W7V
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PERIPLASMIC DOMAIN OF EPSL FROM VIBRIO PARAHAEMOLYTICUS
Descriptor:GENERAL SECRETION PATHWAY PROTEIN L, 1,2-ETHANEDIOL, PHOSPHATE ION
Authors:Abendroth, J., Kreger, A.C., Abendroth, H., Sandkvist, M., Hol, W.G.J.
Deposit date:2009-01-06
Release date:2010-03-31
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Dimer Formed by the Periplasmic Domain of Epsl from the Type 2 Secretion System of Vibrio Parahaemolyticus.
J.Struct.Biol., 168, 2009
1GKP
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D-HYDANTOINASE (DIHYDROPYRIMIDINASE) FROM THERMUS SP. IN SPACE GROUP C2221
Descriptor:HYDANTOINASE, ZINC ION, SULFATE ION, ...
Authors:Abendroth, J., Niefind, K., Schomburg, D.
Deposit date:2001-08-20
Release date:2002-06-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.295 Å)
Cite:X-Ray Structure of a Dihydropyrimidinase from Thermus Sp. At 1.3 A Resolution
J.Mol.Biol., 320, 2002
1YF5
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CYTO-EPSL: THE CYTOPLASMIC DOMAIN OF EPSL, AN INNER MEMBRANE COMPONENT OF THE TYPE II SECRETION SYSTEM OF VIBRIO CHOLERAE
Descriptor:General secretion pathway protein L
Authors:Abendroth, J., Murphy, P., Mushtaq, A., Sandkvist, M., Bagdasarian, M., Hol, W.G.
Deposit date:2004-12-30
Release date:2005-05-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The X-ray Structure of the Type II Secretion System Complex Formed by the N-terminal Domain of EpsE and the Cytoplasmic Domain of EpsL of Vibrio cholerae.
J.Mol.Biol., 348, 2005
1GKQ
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D-HYDANTOINASE (DIHYDROPYRIMIDINASE) FROM THERMUS SP. IN SPACE GROUP P212121
Descriptor:HYDANTOINASE, ZINC ION
Authors:Abendroth, J., Niefind, K., Schomburg, D.
Deposit date:2001-08-20
Release date:2002-06-27
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:X-Ray Structure of a Dihydropyrimidinase from Thermus Sp. At 1.3 A Resolution
J.Mol.Biol., 320, 2002
1GKR
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L-HYDANTOINASE (DIHYDROPYRIMIDINASE) FROM ARTHROBACTER AURESCENS
Descriptor:NON-ATP DEPENDENT L-SELECTIVE HYDANTOINASE, ZINC ION
Authors:Abendroth, J., Niefind, K., Schomburg, D.
Deposit date:2001-08-20
Release date:2002-07-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structure of L-Hydantoinase from Arthobacter Aurescens Leads to an Understanding of Dihydropyrimidinase Substrate and Enantio Specificity.
Biochemistry, 41, 2002
1UV7
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PERIPLASMIC DOMAIN OF EPSM FROM VIBRIO CHOLERAE
Descriptor:GENERAL SECRETION PATHWAY PROTEIN M
Authors:Abendroth, J., Hol, W.G.J.
Deposit date:2004-01-15
Release date:2004-04-23
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Crystal Structure of the Periplasmic Domain of the Type II Secretion System Protein Epsm from Vibrio Cholerae: The Simplest Version of the Ferredoxin Fold
J.Mol.Biol., 338, 2004
1W97
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CYTO-EPSL: THE CYTOPLASMIC DOMAIN OF EPSL, AN INNER MEMBRANE COMPONENT OF THE TYPE II SECRETION SYSTEM OF VIBRIO CHOLERAE
Descriptor:TYPE II SECRETION SYSTEM PROTEIN L
Authors:Abendroth, J., Bagdasarian, M., Sansdkvist, M., Hol, W.G.J.
Deposit date:2004-10-06
Release date:2004-11-30
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Structure of the Cytoplasmic Domain of Epsl, an Inner Membrane Component of the Type II Secretion System of Vibrio Cholerae: An Unusual Member of the Actin-Like ATPase Superfamily
J.Mol.Biol., 344, 2004
2BH1
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X-RAY STRUCTURE OF THE GENERAL SECRETION PATHWAY COMPLEX OF THE N- TERMINAL DOMAIN OF EPSE AND THE CYTOSOLIC DOMAIN OF EPSL OF VIBRIO CHOLERAE
Descriptor:GENERAL SECRETION PATHWAY PROTEIN L, GENERAL SECRETION PATHWAY PROTEIN E,, CALCIUM ION
Authors:Abendroth, J., Murphy, P.M., Mushtaq, A., Bagdasarian, M., Sandkvist, M., Hol, W.G.J.
Deposit date:2005-01-06
Release date:2005-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The X-Ray Structure of the Type II Secretion System Complex Formed by the N-Terminal Domain of Epse and the Cytoplasmic Domain of Epsl of Vibrio Cholerae
J.Mol.Biol., 348, 2005
2VMA
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THE THREE-DIMENSIONAL STRUCTURE OF THE CYTOPLASMIC DOMAINS OF EPSF FROM THE TYPE 2 SECRETION SYSTEM OF VIBRIO CHOLERAE
Descriptor:GENERAL SECRETION PATHWAY PROTEIN F, CALCIUM ION, IODIDE ION
Authors:Abendroth, J., Korotkov, K.V., Mitchell, D.D., Kreger, A., Hol, W.G.J.
Deposit date:2008-01-25
Release date:2009-02-10
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Three-Dimensional Structure of the Cytoplasmic Domains of Epsf from the Type 2 Secretion System of Vibrio Cholerae.
J.Struct.Biol., 166, 2009
2VMB
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THE THREE-DIMENSIONAL STRUCTURE OF THE CYTOPLASMIC DOMAINS OF EPSF FROM THE TYPE 2 SECRETION SYSTEM OF VIBRIO CHOLERAE
Descriptor:GENERAL SECRETION PATHWAY PROTEIN F, CALCIUM ION
Authors:Abendroth, J., Korotkov, K.V., Mitchell, D.D., Kreger, A., Hol, W.G.J.
Deposit date:2008-01-25
Release date:2009-02-10
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Three-Dimensional Structure of the Cytoplasmic Domains of Epsf from the Type 2 Secretion System of Vibrio Cholerae.
J.Struct.Biol., 166, 2009
3C1Q
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THE THREE-DIMENSIONAL STRUCTURE OF THE CYTOPLASMIC DOMAINS OF EPSF FROM THE TYPE 2 SECRETION SYSTEM OF VIBRIO CHOLERAE
Descriptor:General secretion pathway protein F, CALCIUM ION, CHLORIDE ION, ...
Authors:Abendroth, J., Mitchell, D.D., Korotkov, K.V., Kreeger, A., Hol, W.G.J.
Deposit date:2008-01-24
Release date:2009-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The three-dimensional structure of the cytoplasmic domains of EpsF from the type 2 secretion system of Vibrio cholerae
J.Struct.Biol., 166, 2009
3K2E
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CRYSTAL STRUCTURE OF ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE FROM ANAPLASMA PHAGOCYTOPHILUM AT 1.9A RESOLUTION
Descriptor:Enoyl-(Acyl-carrier-protein) reductase, 1,2-ETHANEDIOL, GLYCEROL
Authors:Abendroth, J., Staker, B., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-09-30
Release date:2009-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of enoyl-(acyl-carrier-protein) reductase from Anaplasma phagocytophilum at 1.9A resolution
To be Published
3LRF
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CRYSTAL STRUCTURE OF BETA-KETOACYL SYNTHASE FROM BRUCELLA MELITENSIS
Descriptor:Beta-ketoacyl synthase, SODIUM ION
Authors:Abendroth, J., Edwards, T., Staker, B., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-02-11
Release date:2010-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:CRYSTAL structure of beta-ketoacyl synthase from brucella melitensis
To be Published
3GMT
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CRYSTAL STRUCTURE OF ADENYLATE KINASE FROM BURKHOLDERIA PSEUDOMALLEI
Descriptor:Adenylate kinase, SULFATE ION
Authors:Abendroth, J., Staker, B.L., Robinson, H., Buchko, G.W., Hewitt, S.N., Napuli, A.J., Van Voorhis, W., Stacy, R., Myler, P.J., Stewart, L., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-03-15
Release date:2009-06-02
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural characterization of Burkholderia pseudomallei adenylate kinase (Adk): profound asymmetry in the crystal structure of the 'open' state.
Biochem.Biophys.Res.Commun., 394, 2010
3IFT
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CRYSTAL STRUCTURE OF GLYCINE CLEAVAGE SYSTEM PROTEIN H FROM MYCOBACTERIUM TUBERCULOSIS, USING X-RAYS FROM THE COMPACT LIGHT SOURCE.
Descriptor:Glycine cleavage system H protein
Authors:Edwards, T.E., Abendroth, J., Staker, B., Mayer, C., Phan, I., Kelley, A., Analau, E., Leibly, D., Rifkin, J., Loewen, R., Ruth, R.D., Stewart, L.J., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
Deposit date:2009-07-25
Release date:2009-08-11
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure determination of the glycine cleavage system protein H of Mycobacterium tuberculosis using an inverse Compton synchrotron X-ray source.
J.Struct.Funct.Genom., 11, 2010
4PUB
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CRYSTAL STRUCTURE OF FAB DX-2930
Descriptor:DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN, CHLORIDE ION
Authors:Abendroth, J., Edwards, T.E., Nixon, A., Ladner, R.
Deposit date:2014-03-12
Release date:2014-07-09
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Inhibition of plasma kallikrein by a highly specific active site blocking antibody.
J.Biol.Chem., 289, 2014
3NNU
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CRYSTAL STRUCTURE OF P38 ALPHA IN COMPLEX WITH DP1376
Descriptor:Mitogen-activated protein kinase 14, 2-{3-[(5E)-5-{[(2,3-dichlorophenyl)carbamoyl]imino}-3-thiophen-2-yl-2,5-dihydro-1H-pyrazol-1-yl]phenyl}acetamide
Authors:Abendroth, J.
Deposit date:2010-06-24
Release date:2010-09-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region
Bioorg.Med.Chem.Lett., 20, 2010
3NNV
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CRYSTAL STRUCTURE OF P38 ALPHA IN COMPLEX WITH DP437
Descriptor:Mitogen-activated protein kinase 14, 1-{3-tert-butyl-1-[4-(hydroxymethyl)phenyl]-1H-pyrazol-5-yl}-3-naphthalen-1-ylurea
Authors:Abendroth, J.
Deposit date:2010-06-24
Release date:2010-09-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region
Bioorg.Med.Chem.Lett., 20, 2010
3NNW
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CRYSTAL STRUCTURE OF P38 ALPHA IN COMPLEX WITH DP802
Descriptor:Mitogen-activated protein kinase 14, 2-[3-(3-tert-butyl-5-{[(2,3-dichlorophenyl)carbamoyl]imino}-2,5-dihydro-1H-pyrazol-1-yl)phenyl]acetamide
Authors:Abendroth, J.
Deposit date:2010-06-24
Release date:2010-09-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region
Bioorg.Med.Chem.Lett., 20, 2010
3NNX
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CRYSTAL STRUCTURE OF PHOSPHORYLATED P38 ALPHA IN COMPLEX WITH DP802
Descriptor:Mitogen-activated protein kinase 14, 2-[3-(3-tert-butyl-5-{[(2,3-dichlorophenyl)carbamoyl]imino}-2,5-dihydro-1H-pyrazol-1-yl)phenyl]acetamide
Authors:Abendroth, J.
Deposit date:2010-06-24
Release date:2010-09-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region
Bioorg.Med.Chem.Lett., 20, 2010
1K1D
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CRYSTAL STRUCTURE OF D-HYDANTOINASE
Descriptor:D-hydantoinase, ZINC ION
Authors:Cheon, Y.H., Kim, H.S., Han, K.H., Abendroth, J., Niefind, K., Schomburg, D., Wang, J., Kim, Y.
Deposit date:2001-09-25
Release date:2002-08-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Crystal structure of D-hydantoinase from Bacillus stearothermophilus: insight into the stereochemistry of enantioselectivity.
Biochemistry, 41, 2002
3U0B
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CRYSTAL STRUCTURE OF AN OXIDOREDUCTASE FROM MYCOBACTERIUM SMEGMATIS
Descriptor:Oxidoreductase, short chain dehydrogenase/reductase family protein, SODIUM ION
Authors:Arakaki, T.L., Staker, B.L., Clifton, M.C., Abendroth, J., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-09-28
Release date:2011-10-05
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4EYE
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CRYSTAL STRUCTURE OF A PROBABLE OXIDOREDUCTASE FROM MYCOBACTERIUM ABSCESSUS SOLVED BY IODIDE ION SAD
Descriptor:Probable oxidoreductase, (4S)-2-METHYL-2,4-PENTANEDIOL, IODIDE ION
Authors:Edwards, T.E., Abendroth, J., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-05-01
Release date:2012-05-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4OGX
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CRYSTAL STRUCTURE OF FAB DX-2930 IN COMPLEX WITH HUMAN PLASMA KALLIKREIN AT 2.4 ANGSTROM RESOLUTION
Descriptor:Plasma kallikrein, DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN, ...
Authors:Edwards, T.E., Clifton, M.C., Abendroth, J., Nixon, A., Ladner, R.
Deposit date:2014-01-16
Release date:2014-07-09
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inhibition of plasma kallikrein by a highly specific active site blocking antibody.
J.Biol.Chem., 289, 2014
4OGY
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CRYSTAL STRUCTURE OF FAB DX-2930 IN COMPLEX WITH HUMAN PLASMA KALLIKREIN AT 2.1 ANGSTROM RESOLUTION
Descriptor:Plasma kallikrein, DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN, ...
Authors:Edwards, T.E., Clifton, M.C., Abendroth, J., Nixon, A., Ladner, R.
Deposit date:2014-01-16
Release date:2014-07-09
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Inhibition of plasma kallikrein by a highly specific active site blocking antibody.
J.Biol.Chem., 289, 2014