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4LLH
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BU of 4llh by Molmil
Substrate bound outward-open state of the symporter BetP
Descriptor: 2-(trimethyl-lambda~5~-arsanyl)ethanol, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, CHLORIDE ION, ...
Authors:Perez, C, Faust, B, Ziegler, C.
Deposit date:2013-07-09
Release date:2014-05-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Substrate-bound outward-open state of the betaine transporter BetP provides insights into Na(+) coupling.
Nat Commun, 5, 2014
4C7R
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BU of 4c7r by Molmil
Inward facing conformation of the trimeric betaine transporter BetP in complex with lipids
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, CHLORIDE ION, ...
Authors:Koshy, C, Yildiz, O, Ziegler, C.
Deposit date:2013-09-24
Release date:2013-10-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Evidence for Functional Lipid Interactions in the Betaine Transporter Betp
Embo J., 32, 2013
4AIN
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BU of 4ain by Molmil
Crystal structure of BetP with asymmetric protomers.
Descriptor: 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, CHLORIDE ION, CITRATE ANION, ...
Authors:Koshy, C, Ziegler, C, Yildiz, O.
Deposit date:2012-02-10
Release date:2012-06-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Alternating-Access Mechanism in Conformationally Asymmetric Trimers of the Betaine Transporter Betp.
Nature, 490, 2012
4DOJ
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BU of 4doj by Molmil
Crystal structure of BetP in outward-facing conformation
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, CHLORIDE ION, CHOLINE ION, ...
Authors:Perez, C, Ziegler, C.
Deposit date:2012-02-09
Release date:2012-06-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Alternating-access mechanism in conformationally asymmetric trimers of the betaine transporter BetP.
Nature, 490, 2012
7O0I
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BU of 7o0i by Molmil
Vibrio vulnificus stressosome
Descriptor: Anti-anti-sigma factor, RsbS, negative regulator of sigma-B
Authors:Kaltwasser, S, Heinz, V, Madej, M.G, Pane-Farre, J, Ziegler, C.
Deposit date:2021-03-26
Release date:2022-04-13
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (8.3 Å)
Cite:The Vibrio vulnificus stressosome is an oxygen-sensor involved in regulating iron metabolism
Commun Biol, 2022
5MKE
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BU of 5mke by Molmil
cryoEM Structure of Polycystin-2 in complex with cations and lipids
Descriptor: 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wilkes, M, Madej, M.G, Ziegler, C.
Deposit date:2016-12-04
Release date:2017-01-18
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Molecular insights into lipid-assisted Ca(2+) regulation of the TRP channel Polycystin-2.
Nat. Struct. Mol. Biol., 24, 2017
5MKF
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BU of 5mkf by Molmil
cryoEM Structure of Polycystin-2 in complex with calcium and lipids
Descriptor: 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wilkes, M, Madej, M.G, Ziegler, C.
Deposit date:2016-12-04
Release date:2017-01-18
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Molecular insights into lipid-assisted Ca(2+) regulation of the TRP channel Polycystin-2.
Nat. Struct. Mol. Biol., 24, 2017
7B0U
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BU of 7b0u by Molmil
Stressosome complex from Listeria innocua
Descriptor: RsbR protein, RsbS protein
Authors:Miksys, A, Fu, L, Madej, M.G, Ziegler, C.
Deposit date:2020-11-22
Release date:2021-12-01
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Molecular insights into intra-complex signal transmission during stressosome activation.
Commun Biol, 5, 2022
3GYY
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BU of 3gyy by Molmil
The ectoine binding protein of the TeaABC TRAP transporter TeaA in the Apo-State
Descriptor: Periplasmic substrate binding protein, ZINC ION
Authors:Kuhlmann, S.I, Terwisscha Van Scheltinga, A.C, Ziegler, C.
Deposit date:2009-04-06
Release date:2010-04-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Evidence for an allosteric mechanism of substrate release from membrane-transporter accessory binding proteins
Proc.Natl.Acad.Sci.USA, 108, 2011
3FI1
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BU of 3fi1 by Molmil
NhaA dimer model
Descriptor: Na(+)/H(+) antiporter nhaA
Authors:Appel, M, Hizlan, D, Vinothkumar, K.R, Ziegler, C, Kuehlbrandt, W.
Deposit date:2008-12-10
Release date:2009-01-13
Last modified:2024-02-21
Method:ELECTRON CRYSTALLOGRAPHY (7 Å)
Cite:Conformations of NhaA, the Na/H exchanger from Escherichia coli, in the pH-activated and ion-translocating states
J.Mol.Biol., 386, 2009
2WIT
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BU of 2wit by Molmil
CRYSTAL STRUCTURE OF THE SODIUM-COUPLED GLYCINE BETAINE SYMPORTER BETP FROM CORYNEBACTERIUM GLUTAMICUM WITH BOUND SUBSTRATE
Descriptor: GLYCINE BETAINE TRANSPORTER BETP, TRIMETHYL GLYCINE
Authors:Ressl, S, Terwisscha Van Scheltinga, A.C, Vonrhein, C, Ott, V, Ziegler, C.
Deposit date:2009-05-17
Release date:2009-05-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Molecular Basis of Transport and Regulation in the Na(+)/Betaine Symporter Betp.
Nature, 458, 2009
2VPN
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BU of 2vpn by Molmil
High-resolution structure of the periplasmic ectoine-binding protein from TeaABC TRAP-transporter of Halomonas elongata
Descriptor: (4S)-2-METHYL-1,4,5,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, MAGNESIUM ION, PERIPLASMIC SUBSTRATE BINDING PROTEIN
Authors:Kuhlmann, S.I, Terwisscha van Scheltinga, A.C, Bienert, R, Kunte, H.J, Ziegler, C.
Deposit date:2008-03-03
Release date:2008-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:1.55 A Structure of the Ectoine Binding Protein Teaa of the Osmoregulated Trap-Transporter Teaabc from Halomonas Elongata.
Biochemistry, 47, 2008
2VPO
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BU of 2vpo by Molmil
High resolution structure of the periplasmic binding protein TeaA from TeaABC TRAP transporter of Halomonas elongata in complex with hydroxyectoine
Descriptor: (4S,5S)-5-HYDROXY-2-METHYL-1,4,5,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, MAGNESIUM ION, PERIPLASMIC SUBSTRATE BINDING PROTEIN
Authors:Kuhlmann, S.I, Terwisscha van Scheltinga, A.C, Bienert, R, Kunte, H.J, Ziegler, C.
Deposit date:2008-03-03
Release date:2008-08-26
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:1.55 A Structure of the Ectoine Binding Protein Teaa of the Osmoregulated Trap-Transporter Teaabc from Halomonas Elongata.
Biochemistry, 47, 2008
3P03
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BU of 3p03 by Molmil
Crystal structure of BetP-G153D with choline bound
Descriptor: CHOLINE ION, Glycine betaine transporter BetP
Authors:Perez, C, Ressl, S, Ziegler, Z.
Deposit date:2010-09-27
Release date:2011-03-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Substrate specificity and ion coupling in the Na(+)/betaine symporter BetP.
Embo J., 30, 2011
4QO5
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BU of 4qo5 by Molmil
Hypothetical multiheme protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HEME C, ...
Authors:Rajendran, C.
Deposit date:2014-06-19
Release date:2015-12-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.697 Å)
Cite:In meso crystal structure of a novel membrane-associated octaheme cytochrome c from the Crenarchaeon Ignicoccus hospitalis.
Febs J., 283, 2016
7QE5
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BU of 7qe5 by Molmil
Structure of the membrane domains of the sialic acid TRAP transporter HiSiaQM from Haemophilus influenzae
Descriptor: Megabody3, Sialic acid TRAP transporter permease protein SiaT
Authors:Peter, M.F, Hagelueken, G.
Deposit date:2021-12-01
Release date:2022-07-27
Last modified:2022-08-17
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structural and mechanistic analysis of a tripartite ATP-independent periplasmic TRAP transporter.
Nat Commun, 13, 2022
6F2G
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BU of 6f2g by Molmil
Bacterial asc transporter crystal structure in open to in conformation
Descriptor: Nanobody 74, Putative amino acid/polyamine transport protein, ZINC ION
Authors:Fort, J, Errasti-Murugarren, E, Carpena, X, Palacin, M, Fita, I.
Deposit date:2017-11-24
Release date:2019-04-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:L amino acid transporter structure and molecular bases for the asymmetry of substrate interaction.
Nat Commun, 10, 2019
6F2W
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BU of 6f2w by Molmil
Bacterial asc transporter crystal structure in open to in conformation
Descriptor: ALPHA-AMINOISOBUTYRIC ACID, Nanobody 74, Putative amino acid/polyamine transport protein, ...
Authors:Fort, J, Errasti-Murugarren, E, Carpena, X, Palacin, M, Fita, I.
Deposit date:2017-11-27
Release date:2019-04-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:L amino acid transporter structure and molecular bases for the asymmetry of substrate interaction.
Nat Commun, 10, 2019

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