Author results

1CEH
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STRUCTURE AND FUNCTION OF THE CATALYTIC SITE MUTANT ASP99ASN OF PHOSPHOLIPASE A2: ABSENCE OF CONSERVED STRUCTURAL WATER
分子名称:PHOSPHOLIPASE A2, CALCIUM ION
著者Kumar, A., Sekharudu, C., Ramakrishnan, B., Dupureur, C.M., Zhu, H., Tsai, M.-D., Sundaralingam, M.
登録日1994-11-16
公開日1995-02-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and function of the catalytic site mutant Asp 99 Asn of phospholipase A2: absence of the conserved structural water.
Protein Sci., 3, 1994
1EJ8
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CRYSTAL STRUCTURE OF DOMAIN 2 OF THE YEAST COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE (LYS7) AT 1.55 A RESOLUTION
分子名称:LYS7, CALCIUM ION
著者Hall, L.T., Sanchez, R.J., Holloway, S.P., Zhu, H., Stine, J.E., Lyons, T.J., Demeler, B., Schirf, V., Hansen, J.C., Nersissian, A.M., Valentine, J.S., Hart, P.J.
登録日2000-03-01
公開日2000-04-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献X-ray crystallographic and analytical ultracentrifugation analyses of truncated and full-length yeast copper chaperones for SOD (LYS7): a dimer-dimer model of LYS7-SOD association and copper delivery.
Biochemistry, 39, 2000
1O7T
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METAL NANOCLUSTERS BOUND TO THE FERRIC BINDING PROTEIN FROM NEISSERIA GONORRHOEAE.
分子名称:IRON BINDING PROTEIN, HF OXO CLUSTER HF5, SMALLEST HF-OXO-PHOSPHATE CLUSTER HF3, ...
著者Alexeev, D., Zu, H., Guo, M., Zhong, W., Hunter, D.J.B., Yang, W., Campopiano, D.J., Sadler, P.J.
登録日2002-11-12
公開日2003-02-27
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A novel protein-mineral interface.
Nat. Struct. Biol., 10, 2003
1R1N
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TRI-NUCLEAR OXO-IRON CLUSTERS IN THE FERRIC BINDING PROTEIN FROM N. GONORRHOEAE
分子名称:Ferric-iron Binding Protein, OXO-IRON CLUSTER 1, OXO-IRON CLUSTER 2, ...
著者Zhu, H., Alexeev, D., Hunter, D.J., Campopiano, D.J., Sadler, P.J.
登録日2003-09-24
公開日2004-03-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Oxo-iron clusters in a bacterial iron-trafficking protein: new roles for a conserved motif.
Biochem.J., 376, 2003
1XC1
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OXO ZIRCONIUM(IV) CLUSTER IN THE FERRIC BINDING PROTEIN (FBP)
分子名称:periplasmic iron-binding protein, OXO ZIRCONIUM(IV) CLUSTER
著者Zhong, W., Alexeev, D., Harvey, I., Guo, M., Hunter, D.J.B., Zhu, H., Campopiano, D.J., Sadler, P.J.
登録日2004-08-31
公開日2004-09-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Assembly of an Oxo-Zirconium(IV) Cluster in a Protein Cleft
Angew.Chem.Int.Ed.Engl., 43, 2004
2FAO
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LIGD POLYMERASE DOMAIN
分子名称:probable ATP-dependent DNA ligase, SULFATE ION
著者Zhu, H., Nandakumar, J., Aniukwu, J., Wang, L.K., Glickman, M.S., Lima, C.D., Shuman, S.
登録日2005-12-07
公開日2006-05-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D
Proc.Natl.Acad.Sci.USA, 103, 2006
2FAQ
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LIGD POLYMERASE DOMAIN WITH ATP AND MANGANESE
分子名称:probable ATP-dependent DNA ligase, MANGANESE (II) ION, SULFATE ION, ...
著者Zhu, H., Nandakumar, J., Aniukwu, J., Wang, L.K., Glickman, M.S., Lima, C.D., Shuman, S.
登録日2005-12-07
公開日2006-05-23
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D
Proc.Natl.Acad.Sci.USA, 103, 2006
2FAR
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LIGD POLYMERASE DOMAIN WITH DATP AND MANGANESE
分子名称:probable ATP-dependent DNA ligase, MANGANESE (II) ION, SULFATE ION, ...
著者Zhu, H., Nandakumar, J., Aniukwu, J., Wang, L.K., Glickman, M.S., Lima, C.D., Shuman, S.
登録日2005-12-07
公開日2006-05-23
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D
Proc.Natl.Acad.Sci.USA, 103, 2006
2IA5
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T4 POLYNUCLEOTIDE KINASE/PHOSPHATASE WITH BOUND SULFATE AND MAGNESIUM.
分子名称:Polynucleotide kinase, MAGNESIUM ION, SULFATE ION, ...
著者Zhu, H., Smith, P.C., Wang, L.K., Lima, C.D., Shuman, S.
登録日2006-09-07
公開日2007-06-05
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure-function analysis of the 3' phosphatase component of T4 polynucleotide kinase/phosphatase.
Virology, 366, 2007
2NZT
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CRYSTAL STRUCTURE OF HUMAN HEXOKINASE II
分子名称:Hexokinase-2, ALPHA-D-GLUCOSE, BETA-D-GLUCOSE-6-PHOSPHATE, ...
著者Rabeh, W.M., Zhu, H., Nedyalkova, L., Tempel, W., Wasney, G., Landry, R., Vedadi, M., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2006-11-25
公開日2006-12-05
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure of human hexokinase II
To be Published
2O52
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CRYSTAL STRUCTURE OF HUMAN RAB4B IN COMPLEX WITH GDP
分子名称:Ras-related protein Rab-4B, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
著者Zhu, H., Tempel, W., Wang, J., Shen, Y., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2006-12-05
公開日2006-12-19
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of human RAB4B in complex with GDP
To be Published
2OIL
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CRYSTAL STRUCTURE OF HUMAN RAB25 IN COMPLEX WITH GDP
分子名称:Ras-related protein Rab-25, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
著者Zhu, H., Wang, J., Shen, Y., Tempel, W., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-01-11
公開日2007-01-23
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of human RAB25 in complex with GDP
To be Published
2P57
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GAP DOMAIN OF ZNF289, AN ID1-REGULATED ZINC FINGER PROTEIN
分子名称:GTPase-activating protein ZNF289, ZINC ION, UNKNOWN ATOM OR ION
著者Tong, Y., Dimov, S., Shen, L., Zhu, H., Tempel, W., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-03-14
公開日2007-03-27
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献GAP domain of ZNF289, an ID1-regulated zinc finger protein
To be Published
2P5S
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RAB DOMAIN OF HUMAN RASEF IN COMPLEX WITH GDP
分子名称:RAS and EF-hand domain containing, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION
著者Zhu, H., Wang, J., Shen, Y., Tempel, W., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-03-16
公開日2007-03-27
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献RAB domain of human RASEF in complex with GDP
To be Published
2PH6
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CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE COMPLEXED WITH INHIBITOR
分子名称:Beta-secretase 1, SULFATE ION, 3-({[(1R)-1-(4-FLUOROPHENYL)ETHYL]AMINO}CARBONYL)-5-[METHYL(METHYLSULFONYL)AMINO]BENZYL ALPHA-METHYL-D-PHENYLALANINATE
著者Munshi, S.
登録日2007-04-10
公開日2007-06-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Design, synthesis, and SAR of macrocyclic tertiary carbinamine BACE-1 inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
2PH8
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CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE COMPLEXED WITH INHIBITOR
分子名称:Beta-secretase 1, SULFATE ION, N-[(5R,14R)-5-AMINO-5,14-DIMETHYL-4-OXO-3-OXA-18-AZATRICYCLO[15.3.1.1~7,11~]DOCOSA-1(21),7(22),8,10,17,19-HEXAEN-19-YL]-N-METHYLMETHANESULFONAMIDE
著者Munshi, S.
登録日2007-04-10
公開日2008-04-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
2PMY
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EF-HAND DOMAIN OF HUMAN RASEF
分子名称:RAS and EF-hand domain-containing protein, CALCIUM ION, SULFATE ION, ...
著者Zhu, H., Shen, Y., Wang, J., Tempel, W., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-04-23
公開日2007-05-08
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献EF-hand domain of human RASEF
To be Published
2PXX
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HUMAN PUTATIVE METHYLTRANSFERASE MGC2408
分子名称:Uncharacterized protein MGC2408, UNKNOWN ATOM OR ION, S-ADENOSYL-L-HOMOCYSTEINE
著者Tempel, W., Wu, H., Dombrovsky, L., Zeng, H., Zhu, H., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2007-05-14
公開日2007-05-22
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献An intact SAM-dependent methyltransferase fold is encoded by the human endothelin-converting enzyme-2 gene.
Proteins, 74, 2009
2PZ9
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CRYSTAL STRUCTURE OF PUTATIVE TRANSCRIPTIONAL REGULATOR SCO4942 FROM STREPTOMYCES COELICOLOR
分子名称:Putative regulatory protein, SULFATE ION
著者Filippova, E.V., Chruszcz, M., Xu, X., Zheng, H., Cymborowski, M., Savchenko, A., Edwards, A., Joachimiak, A., Minor, W., Midwest Center for Structural Genomics (MCSG)
登録日2007-05-17
公開日2007-06-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献In situ proteolysis for protein crystallization and structure determination.
Nat.Methods, 4, 2007
2QZK
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CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE COMPLEXED WITH I21
分子名称:Beta-secretase 1, 2-[(5R)-5-amino-5-methyl-4,16-dioxo-14-phenyl-3-oxa-15-azatricyclo[15.3.1.1~7,11~]docosa-1(21),7(22),8,10,12,14,17,19-octaen-19-yl]benzonitrile
著者Munshi, S.
登録日2007-08-16
公開日2008-04-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
2R13
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CRYSTAL STRUCTURE OF HUMAN MITONEET REVEALS A NOVEL [2FE-2S] CLUSTER COORDINATION
分子名称:Zinc finger CDGSH domain-containing protein 1, CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER
著者Hou, X., Liu, R., Ross, S., Smart, E.J., Zhu, H., Gong, W.
登録日2007-08-22
公開日2007-09-11
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystallographic studies of human MitoNEET
J.Biol.Chem., 282, 2007
3B6U
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CRYSTAL STRUCTURE OF THE MOTOR DOMAIN OF HUMAN KINESIN FAMILY MEMBER 3B IN COMPLEX WITH ADP
分子名称:Kinesin-like protein KIF3B, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ...
著者Zhu, H., Shen, Y., Tempel, W., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-10-29
公開日2007-11-13
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Motor domain of human kinesin family member 3B in complex with ADP.
To be Published
3B6V
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CRYSTAL STRUCTURE OF THE MOTOR DOMAIN OF HUMAN KINESIN FAMILY MEMBER 3C IN COMPLEX WITH ADP
分子名称:Kinesin-like protein KIF3C, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ...
著者Zhu, H., Tempel, W., Shen, Y., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-10-29
公開日2007-11-13
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Motor domain of human kinesin family member 3C in complex with ADP.
To be Published
2ZI8
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CRYSTAL STRUCTURE OF THE HSAC EXTRADIOL DIOXYGENASE FROM M. TUBERCULOSIS IN COMPLEX WITH 3,4-DIHYDROXY-9,10-SECONANDROST-1,3,5(10)-TRIENE-9,17-DIONE (DHSA)
分子名称:PROBABLE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE BPHC, FE (II) ION, 3,4-dihydroxy-9,10-secoandrosta-1(10),2,4-triene-9,17-dione
著者D'Angelo, I., Yam, K.C., Eltis, L.D., Strynadka, N.
登録日2008-02-13
公開日2009-02-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis.
Plos Pathog., 5, 2009
3CEQ
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THE TPR DOMAIN OF HUMAN KINESIN LIGHT CHAIN 2 (HKLC2)
分子名称:Kinesin light chain 2
著者Zhu, H., Shen, Y., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2008-02-29
公開日2008-08-12
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The TPR domain of Human Kinesin Light Chain 2 (hKLC2)
To be Published