Author results

3NWN
  • Download 3nwn
  • View 3nwn
Molmil generated image of 3nwn
CRYSTAL STRUCTURE OF THE HUMAN KIF9 MOTOR DOMAIN IN COMPLEX WITH ADP
分子名称:Kinesin-like protein KIF9, MAGNESIUM ION, CHLORIDE ION, ...
著者Zhu, H., Tempel, W., He, H., Shen, Y., Wang, J., Brothers, G., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2010-07-09
公開日2010-07-21
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the human KIF9 motor domain in complex with ADP
To be Published
2O52
  • Download 2o52
  • View 2o52
Molmil generated image of 2o52
CRYSTAL STRUCTURE OF HUMAN RAB4B IN COMPLEX WITH GDP
分子名称:Ras-related protein Rab-4B, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
著者Zhu, H., Tempel, W., Wang, J., Shen, Y., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2006-12-05
公開日2006-12-19
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of human RAB4B in complex with GDP
To be Published
2OIL
  • Download 2oil
  • View 2oil
Molmil generated image of 2oil
CRYSTAL STRUCTURE OF HUMAN RAB25 IN COMPLEX WITH GDP
分子名称:Ras-related protein Rab-25, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
著者Zhu, H., Wang, J., Shen, Y., Tempel, W., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-01-11
公開日2007-01-23
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of human RAB25 in complex with GDP
To be Published
2P5S
  • Download 2p5s
  • View 2p5s
Molmil generated image of 2p5s
RAB DOMAIN OF HUMAN RASEF IN COMPLEX WITH GDP
分子名称:RAS and EF-hand domain containing, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION
著者Zhu, H., Wang, J., Shen, Y., Tempel, W., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-03-16
公開日2007-03-27
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献RAB domain of human RASEF in complex with GDP
To be Published
2PMY
  • Download 2pmy
  • View 2pmy
Molmil generated image of 2pmy
EF-HAND DOMAIN OF HUMAN RASEF
分子名称:RAS and EF-hand domain-containing protein, CALCIUM ION, SULFATE ION, ...
著者Zhu, H., Shen, Y., Wang, J., Tempel, W., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-04-23
公開日2007-05-08
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献EF-hand domain of human RASEF
To be Published
3B6U
  • Download 3b6u
  • View 3b6u
Molmil generated image of 3b6u
CRYSTAL STRUCTURE OF THE MOTOR DOMAIN OF HUMAN KINESIN FAMILY MEMBER 3B IN COMPLEX WITH ADP
分子名称:Kinesin-like protein KIF3B, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ...
著者Zhu, H., Shen, Y., Tempel, W., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-10-29
公開日2007-11-13
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Motor domain of human kinesin family member 3B in complex with ADP.
To be Published
3B6V
  • Download 3b6v
  • View 3b6v
Molmil generated image of 3b6v
CRYSTAL STRUCTURE OF THE MOTOR DOMAIN OF HUMAN KINESIN FAMILY MEMBER 3C IN COMPLEX WITH ADP
分子名称:Kinesin-like protein KIF3C, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ...
著者Zhu, H., Tempel, W., Shen, Y., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2007-10-29
公開日2007-11-13
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Motor domain of human kinesin family member 3C in complex with ADP.
To be Published
3CEQ
  • Download 3ceq
  • View 3ceq
Molmil generated image of 3ceq
THE TPR DOMAIN OF HUMAN KINESIN LIGHT CHAIN 2 (HKLC2)
分子名称:Kinesin light chain 2
著者Zhu, H., Shen, Y., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2008-02-29
公開日2008-08-12
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The TPR domain of Human Kinesin Light Chain 2 (hKLC2)
To be Published
3EDT
  • Download 3edt
  • View 3edt
Molmil generated image of 3edt
CRYSTAL STRUCTURE OF THE MUTATED S328N HKLC2 TPR DOMAIN
分子名称:Kinesin light chain 2, UNKNOWN ATOM OR ION
著者Zhu, H., Shen, Y., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
登録日2008-09-03
公開日2009-02-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of mutated S328N TPR domain of human kinesin light chain 2
To be published
1R1N
  • Download 1r1n
  • View 1r1n
Molmil generated image of 1r1n
TRI-NUCLEAR OXO-IRON CLUSTERS IN THE FERRIC BINDING PROTEIN FROM N. GONORRHOEAE
分子名称:Ferric-iron Binding Protein, OXO-IRON CLUSTER 1, OXO-IRON CLUSTER 2, ...
著者Zhu, H., Alexeev, D., Hunter, D.J., Campopiano, D.J., Sadler, P.J.
登録日2003-09-24
公開日2004-03-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Oxo-iron clusters in a bacterial iron-trafficking protein: new roles for a conserved motif.
Biochem.J., 376, 2003
2FAO
  • Download 2fao
  • View 2fao
Molmil generated image of 2fao
CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LIGD POLYMERASE DOMAIN
分子名称:probable ATP-dependent DNA ligase, SULFATE ION
著者Zhu, H., Nandakumar, J., Aniukwu, J., Wang, L.K., Glickman, M.S., Lima, C.D., Shuman, S.
登録日2005-12-07
公開日2006-05-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D
Proc.Natl.Acad.Sci.USA, 103, 2006
2FAQ
  • Download 2faq
  • View 2faq
Molmil generated image of 2faq
CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LIGD POLYMERASE DOMAIN WITH ATP AND MANGANESE
分子名称:probable ATP-dependent DNA ligase, MANGANESE (II) ION, SULFATE ION, ...
著者Zhu, H., Nandakumar, J., Aniukwu, J., Wang, L.K., Glickman, M.S., Lima, C.D., Shuman, S.
登録日2005-12-07
公開日2006-05-23
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D
Proc.Natl.Acad.Sci.USA, 103, 2006
2FAR
  • Download 2far
  • View 2far
Molmil generated image of 2far
CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LIGD POLYMERASE DOMAIN WITH DATP AND MANGANESE
分子名称:probable ATP-dependent DNA ligase, MANGANESE (II) ION, SULFATE ION, ...
著者Zhu, H., Nandakumar, J., Aniukwu, J., Wang, L.K., Glickman, M.S., Lima, C.D., Shuman, S.
登録日2005-12-07
公開日2006-05-23
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D
Proc.Natl.Acad.Sci.USA, 103, 2006
2IA5
  • Download 2ia5
  • View 2ia5
Molmil generated image of 2ia5
T4 POLYNUCLEOTIDE KINASE/PHOSPHATASE WITH BOUND SULFATE AND MAGNESIUM.
分子名称:Polynucleotide kinase, MAGNESIUM ION, SULFATE ION, ...
著者Zhu, H., Smith, P.C., Wang, L.K., Lima, C.D., Shuman, S.
登録日2006-09-07
公開日2007-06-05
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure-function analysis of the 3' phosphatase component of T4 polynucleotide kinase/phosphatase.
Virology, 366, 2007
6JLQ
  • Download 6jlq
  • View 6jlq
Molmil generated image of 6jlq
CRYSTAL STRUCTURE OF HUMAN USP46-WDR48-WDR20 COMPLEX
分子名称:Ubiquitin carboxyl-terminal hydrolase 46, WD repeat-containing protein 48, WD repeat-containing protein 20,highly similar to WD repeat protein 20,WD repeat-containing protein 20, ...
著者Zhu, H., Zhang, T., Ding, J.
登録日2019-03-06
公開日2019-07-10
最終更新日2020-01-22
実験手法X-RAY DIFFRACTION (3.101 Å)
主引用文献Structural insights into the activation of USP46 by WDR48 and WDR20.
Cell Discov, 5, 2019
5WDH
  • Download 5wdh
  • View 5wdh
Molmil generated image of 5wdh
MOTOR DOMAIN OF HUMAN KINESIN FAMILY MEMBER C1
分子名称:Kinesin-like protein KIFC1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Zhu, H., Tempel, W., He, H., Shen, Y., Wang, J., Brothers, G., Landry, R., Arrowsmith, C.H., Edwards, A.M., Park, H., Structural Genomics Consortium (SGC)
登録日2017-07-05
公開日2017-08-09
最終更新日2017-12-20
実験手法X-RAY DIFFRACTION (2.248 Å)
主引用文献Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein.
Sci Rep, 7, 2017
4XH7
  • Download 4xh7
  • View 4xh7
Molmil generated image of 4xh7
CRYSTAL STRUCTURE OF MUPP1 PDZ4
分子名称:Multiple PDZ domain protein, IMIDAZOLE
著者Liu, Z., Zhu, H., Liu, W.
登録日2015-01-05
公開日2015-03-04
最終更新日2015-03-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Biochemical and structural characterization of MUPP1-PDZ4 domain from Mus musculus.
Acta Biochim.Biophys.Sin., 47, 2015
5FZQ
  • Download 5fzq
  • View 5fzq
Molmil generated image of 5fzq
DESIGNED TPR PROTEIN M4N
分子名称:DESIGNED TPR PROTEIN, SULFATE ION
著者Albrecht, R., Zhu, H., Hartmann, M.D.
登録日2016-03-15
公開日2016-10-12
最終更新日2017-03-15
実験手法X-RAY DIFFRACTION (2.148 Å)
主引用文献Origin of a folded repeat protein from an intrinsically disordered ancestor.
Elife, 5, 2016
5FZR
  • Download 5fzr
  • View 5fzr
Molmil generated image of 5fzr
DESIGNED TPR PROTEIN M4N DELTA C (CF I)
分子名称:DESIGNED TPR PROTEIN
著者Albrecht, R., Zhu, H., Hartmann, M.D.
登録日2016-03-15
公開日2016-10-12
最終更新日2017-03-15
実験手法X-RAY DIFFRACTION (2.045 Å)
主引用文献Origin of a folded repeat protein from an intrinsically disordered ancestor.
Elife, 5, 2016
5FZS
  • Download 5fzs
  • View 5fzs
Molmil generated image of 5fzs
DESIGNED TPR PROTEIN M4N DELTA C (CF II)
分子名称:DESIGNED TPR PROTEIN
著者Albrecht, R., Zhu, H., Hartmann, M.D.
登録日2016-03-15
公開日2016-10-12
最終更新日2017-03-15
実験手法X-RAY DIFFRACTION (1.652 Å)
主引用文献Origin of a folded repeat protein from an intrinsically disordered ancestor.
Elife, 5, 2016
5HSI
  • Download 5hsi
  • View 5hsi
Molmil generated image of 5hsi
CRYSTAL STRUCTURE OF TYROSINE DECARBOXYLASE AT 1.73 ANGSTROMS RESOLUTION
分子名称:Putative decarboxylase, MAGNESIUM ION
著者Ni, Y., Zhou, J., Zhu, H., Zhang, K.
登録日2016-01-25
公開日2016-09-21
最終更新日2020-02-19
実験手法X-RAY DIFFRACTION (1.732 Å)
主引用文献Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding
Sci Rep, 6, 2016
6DCG
  • Download 6dcg
  • View 6dcg
Molmil generated image of 6dcg
DISCOVERY OF MK-8353: AN ORALLY BIOAVAILABLE DUAL MECHANISM ERK INHIBITOR FOR ONCOLOGY
分子名称:Mitogen-activated protein kinase 1, SULFATE ION, (3S)-3-(methylsulfanyl)-1-(2-{4-[4-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl]-3,6-dihydropyridin-1(2H)-yl}-2-oxoethyl)-N-(3-{6-[(propan-2-yl)oxy]pyridin-3-yl}-1H-indazol-5-yl)pyrrolidine-3-carboxamide
著者Boga, S.B., Deng, Y., Zhu, L., Nan, Y., Cooper, A., Shipps Jr., G.W., Doll, R., Shih, N., Zhu, H., Sun, R., Wang, T., Paliwal, S., Tsui, H., Gao, X., Yao, X., Desai, J., Wang, J., Alhassan, A.B., Kelly, J., Patel, M., Muppalla, K., Gudipati, S., Zhang, L., Buevich, A., Hesk, D., Carr, D., Dayananth, P., Mei, H., Cox, K., Sherborne, B., Hruza, A.W., Xiao, L., Jin, W., Long, B., Liu, G., Taylor, S.A., Kirschmeier, P., Windsor, W.T., Bishop, R., Samatar, A.A.
登録日2018-05-06
公開日2018-08-08
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献MK-8353: Discovery of an Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology.
ACS Med Chem Lett, 9, 2018
6N5V
  • Download 6n5v
  • View 6n5v
Molmil generated image of 6n5v
CRYSTAL STRUCTURE OF STRICTOSIDINE IN COMPLEX WITH 1H-INDOLE-4-ETHANAMINE
分子名称:Strictosidine synthase, 2-(1H-indol-4-yl)ethan-1-amine
著者Cai, Y., Shao, N., Xie, H., Futamura, Y., Panjikar, S., Liu, H., Zhu, H., Osada, H., Zou, H.
登録日2018-11-22
公開日2019-11-27
実験手法X-RAY DIFFRACTION (2.549 Å)
主引用文献Crystal Structure of Strictosidine in complex with 1H-indole-4-ethanamine
to be published
1XC1
  • Download 1xc1
  • View 1xc1
Molmil generated image of 1xc1
OXO ZIRCONIUM(IV) CLUSTER IN THE FERRIC BINDING PROTEIN (FBP)
分子名称:periplasmic iron-binding protein, OXO ZIRCONIUM(IV) CLUSTER
著者Zhong, W., Alexeev, D., Harvey, I., Guo, M., Hunter, D.J.B., Zhu, H., Campopiano, D.J., Sadler, P.J.
登録日2004-08-31
公開日2004-09-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Assembly of an Oxo-Zirconium(IV) Cluster in a Protein Cleft
Angew.Chem.Int.Ed.Engl., 43, 2004
2PXX
  • Download 2pxx
  • View 2pxx
Molmil generated image of 2pxx
HUMAN PUTATIVE METHYLTRANSFERASE MGC2408
分子名称:Uncharacterized protein MGC2408, UNKNOWN ATOM OR ION, S-ADENOSYL-L-HOMOCYSTEINE
著者Tempel, W., Wu, H., Dombrovsky, L., Zeng, H., Zhu, H., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2007-05-14
公開日2007-05-22
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献An intact SAM-dependent methyltransferase fold is encoded by the human endothelin-converting enzyme-2 gene.
Proteins, 74, 2009