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3B93
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CRYSTAL STRUCTURE OF HUMAN GITRL
Descriptor:Tumor necrosis factor ligand superfamily member 18
Authors:Song, X.M., Zhou, Z.C.
Deposit date:2007-11-02
Release date:2008-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:crystal structure of human GITRL
To be Published
3B94
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CRYSTAL STRUCTURE OF HUMAN GITRL
Descriptor:Tumor necrosis factor ligand superfamily member 18
Authors:Song, X.M., Zhou, Z.C.
Deposit date:2007-11-02
Release date:2008-02-12
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human GITRL
TO BE PUBLISHED
3UNP
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STRUCTURE OF HUMAN SUN2 SUN DOMAIN
Descriptor:SUN domain-containing protein 2, ACETYL GROUP
Authors:Zhou, Z.C., Greene, M.I.
Deposit date:2011-11-16
Release date:2011-12-21
Last modified:2013-03-06
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structure of Sad1-UNC84 homology (SUN) domain defines features of molecular bridge in nuclear envelope
J.Biol.Chem., 287, 2012
4FZA
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CRYSTAL STRUCTURE OF MST4-MO25 COMPLEX
Descriptor:Calcium-binding protein 39, Serine/threonine-protein kinase MST4, GLYCEROL
Authors:Shi, Z.B., Zhou, Z.C.
Deposit date:2012-07-06
Release date:2013-03-06
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structure of the MST4 in Complex with MO25 Provides Insights into Its Activation Mechanism
Structure, 21, 2013
4FZD
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CRYSTAL STRUCTURE OF MST4-MO25 COMPLEX WITH WSF MOTIF
Descriptor:Calcium-binding protein 39, Serine/threonine-protein kinase MST4, C-terminal peptide from Serine/threonine-protein kinase MST4, ...
Authors:Shi, Z.B., Zhou, Z.C.
Deposit date:2012-07-06
Release date:2013-03-06
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure of the MST4 in Complex with MO25 Provides Insights into Its Activation Mechanism
Structure, 21, 2013
4FZF
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CRYSTAL STRUCTURE OF MST4-MO25 COMPLEX WITH DKI
Descriptor:Calcium-binding protein 39, Serine/threonine-protein kinase MST4, 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE
Authors:Shi, Z.B., Zhou, Z.C.
Deposit date:2012-07-06
Release date:2013-03-06
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (3.64 Å)
Cite:Structure of the MST4 in Complex with MO25 Provides Insights into Its Activation Mechanism
Structure, 21, 2013
4GEH
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CRYSTAL STRUCTURE OF MST4 DIMERIZATION DOMAIN COMPLEX WITH PDCD10
Descriptor:Programmed cell death protein 10, Serine/threonine-protein kinase MST4
Authors:Zhang, M., Shi, Z.B., Zhou, Z.C.
Deposit date:2012-08-02
Release date:2013-04-17
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural mechanism of CCM3 heterodimerization with GCKIII kinases
Structure, 21, 2013
4HK1
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CRYSTAL STRUCTURE OF PCNA FROM DROSOPHILA MELANOGASTER
Descriptor:Proliferating cell nuclear antigen
Authors:Wang, K., Shi, Z.B., Zhou, Z.C.
Deposit date:2012-10-14
Release date:2013-04-10
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structure of PCNA from Drosophila melanogaster.
Acta Crystallogr.,Sect.F, 69, 2013
4HKD
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CRYSTAL STRUCTURE OF HUMAN MST2 SARAH DOMAIN
Descriptor:Serine/threonine-protein kinase 3
Authors:Liu, G.G., Shi, Z.B., Zhou, Z.C.
Deposit date:2012-10-15
Release date:2013-09-04
Method:X-RAY DIFFRACTION (1.503 Å)
Cite:Crystal structure of human MST2 SARAH domain
To be Published
4I1L
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STRUCTURAL AND BIOLOGICAL FEATURES OF FOXP3 DIMERIZATION RELEVANT TO REGULATORY T CELL FUNCTION
Descriptor:Forkhead box protein P3, SULFATE ION, MAGNESIUM ION, ...
Authors:Song, X.M., Greene, M.I., Zhou, Z.C.
Deposit date:2012-11-21
Release date:2012-12-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and biological features of FOXP3 dimerization relevant to regulatory T cell function.
Cell Rep, 1, 2012
4N6J
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CRYSTAL STRUCTURE OF HUMAN STRIATIN-3 COILED COIL DOMAIN
Descriptor:Striatin-3
Authors:Chen, C.C., Shi, Z.B., Zhou, Z.C.
Deposit date:2013-10-13
Release date:2014-02-26
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Striatins Contain a Noncanonical Coiled Coil That Binds PP2A A to Form a 2:2 Heterotetrameric Core of Striatin-interacting Phosphatase and Kinase (STRIPAK) Complex
J.Biol.Chem., 2014
4NT4
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CRYSTAL STRUCTURE OF THE KINASE DOMAIN OF GILGAMESH ISOFORM I FROM DROSOPHILA MELANOGASTER
Descriptor:Gilgamesh, isoform I, SULFATE ION, ...
Authors:Chen, C.C., Shi, Z.B., Zhou, Z.C.
Deposit date:2013-11-30
Release date:2014-04-09
Last modified:2015-03-11
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structure of the kinase domain of Gilgamesh from Drosophila melanogaster
Acta Crystallogr.,Sect.F, 70, 2014
4NZW
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CRYSTAL STRUCTURE OF STK25-MO25 COMPLEX
Descriptor:Calcium-binding protein 39, Serine/threonine-protein kinase 25, 5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE
Authors:Feng, M., Hao, Q., Zhou, Z.C.
Deposit date:2013-12-13
Release date:2014-12-03
Method:X-RAY DIFFRACTION (3.583 Å)
Cite:Structural insights into regulatory mechanisms of MO25-mediated kinase activation.
J.Struct.Biol., 186, 2014
4O27
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CRYSTAL STRUCTURE OF MST3-MO25 COMPLEX WITH WIF MOTIF
Descriptor:Calcium-binding protein 39, Serine/threonine-protein kinase 24, 5-mer peptide from serine/threonine-protein kinase 24, ...
Authors:Hao, Q., Feng, M., Zhou, Z.C.
Deposit date:2013-12-16
Release date:2014-12-03
Method:X-RAY DIFFRACTION (3.185 Å)
Cite:Structural insights into regulatory mechanisms of MO25-mediated kinase activation.
J.Struct.Biol., 186, 2014
4RV0
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CRYSTAL STRUCTURE OF TN COMPLEX
Descriptor:Transitional endoplasmic reticulum ATPase TER94, Nuclear protein localization protein 4 homolog, SULFATE ION
Authors:Hao, Q., Jiao, S., Shi, Z.B., Zhou, Z.C.
Deposit date:2014-11-23
Release date:2015-11-25
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Crystal structure of TN complex
To be Published
5GZB
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CRYSTAL STRUCTURE OF TRANSCRIPTION FACTOR TEAD4 IN COMPLEX WITH M-CAT DNA
Descriptor:Transcriptional enhancer factor TEF-3, DNA (5'-D(*TP*TP*GP*CP*AP*TP*TP*CP*CP*TP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*AP*GP*GP*AP*AP*TP*GP*CP*AP*A)-3'), ...
Authors:He, F., Shi, Z.B., Zhou, Z.C.
Deposit date:2016-09-28
Release date:2017-04-19
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:DNA-binding mechanism of the Hippo pathway transcription factor TEAD4
Oncogene, 36, 2017
5XY9
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STRUCTURE OF THE MST4 AND 14-3-3 COMPLEX
Descriptor:14-3-3 protein zeta/delta, Peptide from Serine/threonine-protein kinase 26, GLYCEROL, ...
Authors:Shi, Z.B., Zhou, Z.C.
Deposit date:2017-07-06
Release date:2018-07-11
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:Structure of the MST4 and 14-3-3 complex
To Be Published
5YF4
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A KINASE COMPLEX MST4-MOB4
Descriptor:MOB-like protein phocein, Peptide from Serine/threonine-protein kinase 26, ZINC ION
Authors:Chen, M., Zhou, Z.C.
Deposit date:2017-09-20
Release date:2018-08-15
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (1.897 Å)
Cite:The MST4-MOB4 complex disrupts the MST1-MOB1 complex in the Hippo-YAP pathway and plays a pro-oncogenic role in pancreatic cancer.
J. Biol. Chem., 293, 2018
6AKK
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CRYSTAL STRUCTURE OF THE SECOND COILED-COIL DOMAIN OF SIKE1
Descriptor:Suppressor of IKBKE 1, GLYCEROL
Authors:Zhou, L., Chen, M., Zhou, Z.C.
Deposit date:2018-09-02
Release date:2019-01-16
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling.
Cell Discov, 5, 2019
6AKL
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CRYSTAL STRUCTURE OF STRIATIN3 IN COMPLEX WITH SIKE1 COILED-COIL DOMAIN
Descriptor:Suppressor of IKBKE 1, Striatin-3
Authors:Zhou, L., Chen, M., Zhou, Z.C.
Deposit date:2018-09-02
Release date:2019-01-16
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling.
Cell Discov, 5, 2019
6AKM
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CRYSTAL STRUCTURE OF SLMAP-SIKE1 COMPLEX
Descriptor:Suppressor of IKBKE 1, Sarcolemmal membrane-associated protein, GLYCEROL
Authors:Ma, J., Chen, M., Zhou, Z.C.
Deposit date:2018-09-02
Release date:2019-01-16
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling.
Cell Discov, 5, 2019