Author results

4INZ
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THE CRYSTAL STRUCTURE OF M145A MUTANT OF AN EPOXIDE HYDROLASE FROM BACILLUS MEGATERIUM
Descriptor:Soluble epoxide hydrolase, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER
Authors:Kong, X.D., Zhou, J.H., Xu, J.H.
Deposit date:2013-01-07
Release date:2014-02-12
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates.
Proc.Natl.Acad.Sci.USA, 111, 2014
4IO0
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CRYSTAL STRUCTURE OF F128A MUTANT OF AN EPOXIDE HYDROLASE FROM BACILLUS MEGATERIUM COMPLEXED WITH ITS PRODUCT (R)-3-[1]NAPHTHYLOXY-PROPANE-1,2-DIOL
Descriptor:Soluble epoxide hydrolase, SULFATE ION, (2R)-3-(naphthalen-1-yloxy)propane-1,2-diol
Authors:Kong, X.D., Zhou, J.H., Xu, J.H.
Deposit date:2013-01-07
Release date:2014-02-12
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates.
Proc.Natl.Acad.Sci.USA, 111, 2014
4OB6
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COMPLEX STRUCTURE OF ESTERASE RPPE S159A/W187H AND SUBSTRATE (S)-AC-CPA
Descriptor:Alpha/beta hydrolase fold-3 domain protein, (2S)-(acetyloxy)(2-chlorophenyl)ethanoic acid
Authors:Dou, S., Kong, X.D., Ma, B.D., Chen, Q., Zhou, J.H., Xu, J.H.
Deposit date:2014-01-07
Release date:2014-07-23
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
4OB7
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CRYSTAL STRUCTURE OF ESTERASE RPPE MUTANT W187H
Descriptor:Alpha/beta hydrolase fold-3 domain protein, (4S)-2-METHYL-2,4-PENTANEDIOL, DI(HYDROXYETHYL)ETHER
Authors:Dou, S., Kong, X.D., Ma, B.D., Xu, J.H., Zhou, J.H.
Deposit date:2014-01-07
Release date:2014-07-23
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
4OB8
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CRYSTAL STRUCTURE OF A NOVEL THERMOSTABLE ESTERASE FROM PSEUDOMONAS PUTIDA ECU1011
Descriptor:Alpha/beta hydrolase fold-3 domain protein, (4S)-2-METHYL-2,4-PENTANEDIOL, DI(HYDROXYETHYL)ETHER
Authors:Dou, S., Kong, X.D., Ma, B.D., Xu, J.H., Zhou, J.H.
Deposit date:2014-01-07
Release date:2014-07-23
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
4OU4
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CRYSTAL STRUCTURE OF ESTERASE RPPE MUTANT S159A COMPLEXED WITH (S)-AC-CPA
Descriptor:Alpha/beta hydrolase fold-3 domain protein, (2S)-(acetyloxy)(2-chlorophenyl)ethanoic acid
Authors:Dou, S., Kong, X.D., Ma, B.D., Xu, J.H., Zhou, J.H.
Deposit date:2014-02-15
Release date:2014-07-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
4OU5
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CRYSTAL STRUCTURE OF ESTERASE RPPE MUTANT S159A/W187H
Descriptor:Alpha/beta hydrolase fold-3 domain protein, (4S)-2-METHYL-2,4-PENTANEDIOL, DI(HYDROXYETHYL)ETHER
Authors:Dou, S., Kong, X.D., Ma, B.D., Xu, J.H., Zhou, J.H.
Deposit date:2014-02-15
Release date:2014-07-23
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
4XUK
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CRYSTAL STRUCTURE OF HYDROLASE ABOPH IN BETA LACTAMASE SUPERFAMILY
Descriptor:Putative hydrolase, ZINC ION
Authors:Chen, J., Xu, J.H., Zhou, J.H.
Deposit date:2015-01-26
Release date:2015-10-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Marked enhancement of Acinetobacter sp. organophosphorus hydrolase activity by a single residue substitution Ile211Ala
Bioresour Bioprocess, 2015
5D74
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THE CRYSTAL STRUCTURE OF LY7917
Descriptor:Putative phage lysin, CHLORIDE ION, SODIUM ION
Authors:Wu, L., Ji, W.H., Sun, J.H., Zhou, J.H.
Deposit date:2015-08-13
Release date:2016-08-17
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of Ly7917
To Be Published
5D76
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THE CRYSTAL STRUCTURE OF LY7917 WITH THE HYDROLYZING PRODUCT OF MDP
Descriptor:Putative phage lysin, CHLORIDE ION, L-alanyl-D-alpha-glutamine
Authors:Wu, L., Ji, W.H., Sun, J.H., Zhou, J.H.
Deposit date:2015-08-13
Release date:2016-08-17
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:The crystal structure of Ly7917
To Be Published
5XM6
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THE OVERALL STRUCTURE OF VREH2
Descriptor:Epoxide hydrolase
Authors:Li, F.L., Kong, X.D., Yu, H.L., Shang, Y.P., Zhou, J.H., Xu, J.H.
Deposit date:2017-05-12
Release date:2018-09-05
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Regioselectivity Engineering of Epoxide Hydrolase: Near-Perfect Enantioconvergence through a Single Site Mutation
Acs Catalysis, 8, 2018
5XMD
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CRYSTAL STRUCTURE OF EPOXIDE HYDROLASE VREH1 FROM VIGNA RADIATA
Descriptor:Epoxide hydrolase A
Authors:Kong, X.D., Xu, J.H., Zhou, J.H.
Deposit date:2017-05-14
Release date:2018-05-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Carboxyl reductase
to be published
5Y5D
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THE CRYSTAL STRUCTURE OF VREH2 MUTANT M263W
Descriptor:Epoxide hydrolase
Authors:Xu, J.H., Yu, H.L., Zhou, J.H., Kong, X.D., Li, F.L.
Deposit date:2017-08-08
Release date:2018-12-05
Last modified:2019-08-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The crystal structure of VrEH2 mutant M263W
To Be Published
5Y6Y
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THE CRYSTAL STRUCTURE OF VREH2 MUTANT M263N
Descriptor:Epoxide hydrolase
Authors:Li, F.L., Yu, H.L., Chen, Q., Kong, X.D., Zhou, J.H., Xu, J.H.
Deposit date:2017-08-15
Release date:2018-09-05
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Regioselectivity Engineering of Epoxide Hydrolase: Near-Perfect Enantioconvergence through a Single Site Mutation
Acs Catalysis, 8, 2018
5Z2X
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STRUCTURE OF ALCOHOL DEHYDROGENASE FROM KLUYVEROMYCES POLYSPORA(KPADH)
Descriptor:Alcohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
Authors:Wang, Y., Zhou, J.Y., Hou, X.D., Xu, G.C., Wu, L., Rao, Y.J., ZHou, J.H., Ni, Y.
Deposit date:2018-01-04
Release date:2019-01-02
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural Insight into Enantioselective Inversion of an Alcohol Dehydrogenase Reveals a "Polar Gate" in Stereorecognition of Diaryl Ketones.
J. Am. Chem. Soc., 140, 2018
5ZEC
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CRYSTAL STRUCTURE OF KLUYVEROMYCES POLYSPORA ADH (KPADH) MUTANT (Q136N/F161V/S196G/E214G/S237C)
Descriptor:Uncharacterized protein ADH, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 1,2-ETHANEDIOL, ...
Authors:Wang, Y., ZHou, J.Y., Hou, X.D., Xu, G.C., Rao, Y.J., Wu, L., Zhou, J.H., Ni, Y.
Deposit date:2018-02-27
Release date:2019-01-02
Method:X-RAY DIFFRACTION (1.779 Å)
Cite:Structural Insight into Enantioselective Inversion of an Alcohol Dehydrogenase Reveals a "Polar Gate" in Stereorecognition of Diaryl Ketones.
J. Am. Chem. Soc., 140, 2018
5ZED
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CRYSTAL STRUCTURE OF KLUYVEROMYCES POLYSPORA ADH (KPADH) MUTANT (E214V/T215S)
Descriptor:Uncharacterized protein ADH, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wang, Y., Zhou, J.Y., Hou, X.D., Xu, G.C., Wu, L., Rao, Y.J., ZHou, J.H., Ni, Y.
Deposit date:2018-02-27
Release date:2019-01-02
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Structural Insight into Enantioselective Inversion of an Alcohol Dehydrogenase Reveals a "Polar Gate" in Stereorecognition of Diaryl Ketones.
J. Am. Chem. Soc., 140, 2018
3KCC
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CRYSTAL STRUCTURE OF D138L MUTANT OF CATABOLITE GENE ACTIVATOR PROTEIN
Descriptor:Catabolite gene activator, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
Authors:Tao, W.B., Gao, Z.Q., Zhou, J.H., Dong, Y.H., Yu, S.N.
Deposit date:2009-10-21
Release date:2009-11-17
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:The 1.6A resolution structure of activated D138L mutant of catabolite gene activator protein with two cAMP bound in each monomer
Int.J.Biol.Macromol., 48, 2011
4ELS
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STRUCTURE OF E. COLI. 1,4-DIHYDROXY-2- NAPHTHOYL COENZYME A SYNTHASES (MENB) IN COMPLEX WITH BICARBONATE
Descriptor:1,4-Dihydroxy-2-naphthoyl-CoA synthase, BICARBONATE ION, GLYCEROL, ...
Authors:Sun, Y.R., Song, H.G., Li, J., Jiang, M., Li, Y., Zhou, J.H., Guo, Z.H.
Deposit date:2012-04-11
Release date:2012-06-06
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:Active site binding and catalytic role of bicarbonate in 1,4-dihydroxy-2-naphthoyl coenzyme A synthases from vitamin K biosynthetic pathways
Biochemistry, 51, 2012
4ELW
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STRUCTURE OF E. COLI. 1,4-DIHYDROXY-2- NAPHTHOYL COENZYME A SYNTHASES (MENB) IN COMPLEX WITH NITRATE
Descriptor:1,4-Dihydroxy-2-naphthoyl-CoA synthase, NITRATE ION, SUCCINIC ACID, ...
Authors:Sun, Y.R., Song, H.G., Li, J., Jiang, M., Li, Y., Zhou, J.H., Guo, Z.H.
Deposit date:2012-04-11
Release date:2012-06-06
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.551 Å)
Cite:Active site binding and catalytic role of bicarbonate in 1,4-dihydroxy-2-naphthoyl coenzyme A synthases from vitamin K biosynthetic pathways
Biochemistry, 51, 2012
4ELX
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STRUCTURE OF APO E.COLI. 1,4-DIHYDROXY-2- NAPHTHOYL COA SYNTHASES WITH CL
Descriptor:1,4-Dihydroxy-2-naphthoyl-CoA synthase, GLYCEROL, CHLORIDE ION, ...
Authors:Sun, Y.R., Song, H.G., Li, J., Jiang, M., Li, Y., Zhou, J.H., Guo, Z.H.
Deposit date:2012-04-11
Release date:2012-06-06
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.191 Å)
Cite:Active site binding and catalytic role of bicarbonate in 1,4-dihydroxy-2-naphthoyl coenzyme A synthases from vitamin K biosynthetic pathways
Biochemistry, 51, 2012
5CF1
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CRYSTAL STRUCTURE OF THE M32V/M78V/I80V/L114F MUTANT OF LEH
Descriptor:Limonene-1,2-epoxide hydrolase
Authors:Wu, L., Sun, Z.T., Reetz, M.T., Zhou, J.H.
Deposit date:2015-07-08
Release date:2016-07-13
Method:X-RAY DIFFRACTION (2.242 Å)
Cite:Crystal Structure of the M32V/M78V/I80V/L114F mutant of LEH
To Be Published
5CF2
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CRYSTAL STRUCTURE OF THE I80Y/L114V/I116V MUTANT OF LEH
Descriptor:Limonene-1,2-epoxide hydrolase
Authors:Wu, L., Sun, Z.T., Reetz, M.T., Zhou, J.H.
Deposit date:2015-07-08
Release date:2016-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of the I80Y/L114V/I116V mutant of LEH
To Be Published
5CK6
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CRYSTAL STRUCTURE OF SZ348 IN COMPLEX WITH CYCLOPENTENE OXIDE
Descriptor:Limonene-1,2-epoxide hydrolase, (1R,5S)-6-oxabicyclo[3.1.0]hexane, POTASSIUM ION, ...
Authors:Wu, L., Sun, Z.T., Reetz, M.T., Zhou, J.H.
Deposit date:2015-07-15
Release date:2016-07-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of SZ348 in complex with cyclopentene oxide
To Be Published
5CLK
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CRYSTAL STRUCTURE OF SZ348 IN COMPLEX WITH S,S-CYCLOHEXANEDIOL
Descriptor:Limonene-1,2-epoxide hydrolase, NICKEL (II) ION, (1S,2S)-cyclohexane-1,2-diol, ...
Authors:Wu, L., Sun, Z.T., Reetz, M.T., Zhou, J.H.
Deposit date:2015-07-16
Release date:2016-07-20
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Crystal structure of SZ348 in complex with S,S-cyclohexanediol
To Be Published
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