Author results

1AAX
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CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH TWO BIS(PARA-PHOSPHOPHENYL)METHANE (BPPM) MOLECULES
Descriptor:PROTEIN TYROSINE PHOSPHATASE 1B, MAGNESIUM ION, 4-PHOSPHONOOXY-PHENYL-METHYL-[4-PHOSPHONOOXY]BENZEN
Authors:Puius, Y.A., Zhao, Y., Sullivan, M., Lawrence, D., Almo, S.C., Zhang, Z.-Y.
Deposit date:1997-01-16
Release date:1998-03-04
Last modified:2012-07-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design.
Proc.Natl.Acad.Sci.USA, 94, 1997
1BF5
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TYROSINE PHOSPHORYLATED STAT-1/DNA COMPLEX
Descriptor:DNA (5'-D(*AP*CP*AP*GP*TP*TP*TP*CP*CP*CP*GP*TP*AP*AP*AP*TP*G P*C)-3'), DNA (5'-D(*TP*GP*CP*AP*TP*TP*TP*AP*CP*GP*GP*GP*AP*AP*AP*CP*T P*G)-3'), SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA/BETA
Authors:Kuriyan, J., Zhao, Y., Chen, X., Vinkemeier, U., Jeruzalmi, D., Darnell Jr., J.E.
Deposit date:1998-05-27
Release date:1998-08-12
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA.
Cell(Cambridge,Mass.), 93, 1998
1D5A
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CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK. DEPOSITION OF SECOND NATIVE STRUCTURE AT 2.4 ANGSTROM
Descriptor:PROTEIN (DNA POLYMERASE), SULFATE ION, MAGNESIUM ION
Authors:Zhao, Y., Jeruzalmi, D., Leighton, L., Lasken, R., Kuriyan, J.
Deposit date:1999-10-06
Release date:2000-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of an archaebacterial DNA polymerase.
Structure Fold.Des., 7, 1999
1EEN
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CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH ACETYL-D-A-D-BPA-PTYR-L-I-P-Q-Q-G
Descriptor:PROTEIN TYROSINE PHOSPHATASE 1B, ALA-ASP-PBF-PTR-LEU-ILE-PRO, MAGNESIUM ION, ...
Authors:Puius, Y.A., Zhao, Y., Almo, S.C., Zhang, Z.Y.
Deposit date:2000-02-01
Release date:2001-02-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition.
Biochemistry, 39, 2000
1EEO
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CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH ACETYL-E-L-E-F-PTYR-M-D-Y-E-NH2
Descriptor:PROTEIN TYROSINE PHOSPHATASE 1B, ACETYL-E-L-E-F-PTYR-M-D-Y-E-NH2 PEPTIDE, MAGNESIUM ION
Authors:Sarmiento, M., Puius, Y.A., Vetter, S.W., Lawrence, D.S., Almo, S.C., Zhang, Z.Y.
Deposit date:2000-02-01
Release date:2001-02-01
Last modified:2012-07-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition.
Biochemistry, 39, 2000
1EV7
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CRYSTAL STRUCTURE OF DNA RESTRICTION ENDONUCLEASE NAEI
Descriptor:TYPE IIE RESTRICTION ENDONUCLEASE NAEI
Authors:Huai, Q., Colandene, J.D., Chen, Y., Luo, F., Zhao, Y.
Deposit date:2000-04-19
Release date:2000-10-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of NaeI-an evolutionary bridge between DNA endonuclease and topoisomerase.
EMBO J., 19, 2000
1F0J
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CATALYTIC DOMAIN OF HUMAN PHOSPHODIESTERASE 4B2B
Descriptor:PHOSPHODIESTERASE 4B, ZINC ION, MAGNESIUM ION, ...
Authors:Xu, R.X., Hassell, A.M., Vanderwall, D., Lambert, M.H., Holmes, W.D., Luther, M.A., Rocque, W.J., Milburn, M.V., Zhao, Y., Ke, H., Nolte, R.T.
Deposit date:2000-05-16
Release date:2000-07-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity.
Science, 288, 2000
1FGL
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CYCLOPHILIN A COMPLEXED WITH A FRAGMENT OF HIV-1 GAG PROTEIN
Descriptor:CYCLOPHILIN A, HIV-1 GAG PROTEIN
Authors:Zhao, Y., Chen, Y., Schutkowski, M., Fischer, G., Ke, H.
Deposit date:1996-11-18
Release date:1997-04-01
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cyclophilin A complexed with a fragment of HIV-1 gag protein: insights into HIV-1 infectious activity.
Structure, 5, 1997
1JQJ
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MECHANISM OF PROCESSIVITY CLAMP OPENING BY THE DELTA SUBUNIT WRENCH OF THE CLAMP LOADER COMPLEX OF E. COLI DNA POLYMERASE III: STRUCTURE OF THE BETA-DELTA COMPLEX
Descriptor:DNA polymerase III, beta chain, delta subunit
Authors:Jeruzalmi, D., Yurieva, O., Zhao, Y., Young, M., Stewart, J., Hingorani, M., O'Donnell, M., Kuriyan, J.
Deposit date:2001-08-07
Release date:2001-11-07
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III.
Cell(Cambridge,Mass.), 106, 2001
1JQL
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MECHANISM OF PROCESSIVITY CLAMP OPENING BY THE DELTA SUBUNIT WRENCH OF THE CLAMP LOADER COMPLEX OF E. COLI DNA POLYMERASE III: STRUCTURE OF BETA-DELTA (1-140)
Descriptor:DNA Polymerase III, BETA CHAIN, DELTA SUBUNIT
Authors:Jeruzalmi, D., Yurieva, O., Zhao, Y., Young, M., Stewart, J., Hingorani, M., O'Donnell, M., Kuriyan, J.
Deposit date:2001-08-07
Release date:2001-09-26
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III.
Cell(Cambridge,Mass.), 106, 2001
1M63
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CRYSTAL STRUCTURE OF CALCINEURIN-CYCLOPHILIN-CYCLOSPORIN SHOWS COMMON BUT DISTINCT RECOGNITION OF IMMUNOPHILIN-DRUG COMPLEXES
Descriptor:SERINE/THREONINE PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT, ALPHA ISOFORM, CALCINEURIN B SUBUNIT ISOFORM 1, ...
Authors:Huai, Q., Kim, H.-Y., Liu, Y., Zhao, Y., Mondragon, A., Liu, J.O., Ke, H.
Deposit date:2002-07-12
Release date:2002-09-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Calcineurin-Cyclophilin-Cyclosporin Shows Common But Distinct Recognition of Immunophilin-Drug Complexes
Proc.Natl.Acad.Sci.USA, 99, 2002
1ONS
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI HEAT SHOCK PROTEIN YEDU
Descriptor:Chaperone protein hchA, ZINC ION
Authors:Zhao, Y., Fox, R.O.
Deposit date:2003-02-28
Release date:2004-01-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of Escherichia coli heat shock protein YedU reveals three potential catalytic active sites
Protein Sci., 12, 2003
1PTY
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CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH TWO PHOSPHOTYROSINE MOLECULES
Descriptor:PROTEIN TYROSINE PHOSPHATASE 1B, MAGNESIUM ION, O-PHOSPHOTYROSINE
Authors:Zhao, Y., Puius, Y.A., Sullivan, M., Lawrence, D., Almo, S.C., Zhang, Z.-Y.
Deposit date:1997-01-16
Release date:1998-01-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design.
Proc.Natl.Acad.Sci.USA, 94, 1997
1Q2B
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CELLOBIOHYDROLASE CEL7A WITH DISULPHIDE BRIDGE ADDED ACROSS EXO-LOOP BY MUTATIONS D241C AND D249C
Descriptor:EXOCELLOBIOHYDROLASE I, N-ACETYL-D-GLUCOSAMINE, COBALT (II) ION
Authors:Stahlberg, J., Harris, M., Jones, T.A.
Deposit date:2003-07-24
Release date:2003-11-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Engineering the exo-loop of Trichoderma reesei cellobiohydrolase, Cel7A. A comparison with Phanerochaete chrysosporium Cel7D.
J.Mol.Biol., 333, 2003
1Q2E
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CELLOBIOHYDROLASE CEL7A WITH LOOP DELETION 245-252 AND BOUND NON-HYDROLYSABLE CELLOTETRAOSE
Descriptor:EXOCELLOBIOHYDROLASE I, O1-METHYL-GLUCOSE, 4-DEOXY-4-THIO-BETA-D-GLUCOPYRANOSE, ...
Authors:Stahlberg, J., Harris, M., Jones, T.A.
Deposit date:2003-07-24
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Engineering the exo-loop of Trichoderma reesei cellobiohydrolase, Cel7A. A comparison with Phanerochaete chrysosporium Cel7D
J.Mol.Biol., 333, 2003
1QQC
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CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK
Descriptor:DNA POLYMERASE II, SULFATE ION, MAGNESIUM ION
Authors:Zhao, Y., Jeruzalmi, D., Leighton, L., Lasken, R., Kuriyan, J.
Deposit date:1999-06-02
Release date:1999-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of an archaebacterial DNA polymerase
Structure Fold.Des., 7, 1999
1R5I
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CRYSTAL STRUCTURE OF THE MAM-MHC COMPLEX
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
Authors:Zhao, Y., Li, Z., Drozd, S.J., Guo, Y., Mourad, W., Li, H.
Deposit date:2003-10-10
Release date:2004-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of Mycoplasma arthritidis mitogen complexed with HLA-DR1 reveals a novel superantigen fold and a dimerized superantigen-MHC complex.
Structure, 12, 2004
1RMH
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RECOMBINANT CYCLOPHILIN A FROM HUMAN T CELL
Descriptor:CYCLOPHILIN A, AAPF PEPTIDE SUBSTRATE
Authors:Zhao, Y., Ke, H.
Deposit date:1995-07-31
Release date:1996-10-14
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure implies that cyclophilin predominantly catalyzes the trans to cis isomerization.
Biochemistry, 35, 1996
1TXJ
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CRYSTAL STRUCTURE OF TRANSLATIONALLY CONTROLLED TUMOUR-ASSOCIATED PROTEIN (TCTP) FROM PLASMODIUM KNOWLESI
Descriptor:translationally controlled tumour-associated protein (TCTP) from Plasmodium knowlesi, PKN_PFE0545c
Authors:Walker, J.R., Vedadi, M., Sharma, S., Houston, S., Lew, J., Amani, M., Wasney, G., Skarina, T., Bray, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Hui, R., Structural Genomics Consortium (SGC)
Deposit date:2004-07-05
Release date:2004-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1VBS
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STRUCTURE OF CYCLOPHILIN COMPLEXED WITH (D)ALA CONTAINING TETRAPEPTIDE
Descriptor:CYCLOPHILIN A, TETRAPEPTIDE
Authors:Zhao, Y., Chen, Y., Schutkowski, M., Fischer, G., Ke, H.
Deposit date:1998-06-16
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mapping the stereospecificity of peptidyl prolyl cis/trans isomerases.
FEBS Lett., 432, 1998
1VBT
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STRUCTURE OF CYCLOPHILIN COMPLEXED WITH SULFUR-SUBSTITUTED TETRAPEPTIDE AAPF
Descriptor:CYCLOPHILIN A, SULFUR-SUBSTITUTED TETRAPEPTIDE
Authors:Zhao, Y., Chen, Y., Schutkowski, M., Fischer, G., Ke, H.
Deposit date:1998-06-16
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Insight Into Conversion of Substrate to Inhibitor
To be Published
1XCC
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1-CYS PEROXIDOXIN FROM PLASMODIUM YOELLI
Descriptor:1-Cys peroxiredoxin
Authors:Vedadi, M., Sharma, S., Houston, S., Lew, J., Wasney, G., Amani, M., Xu, X., Bray, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Hui, R., Bochkarev, A., Structural Genomics Consortium (SGC)
Deposit date:2004-09-01
Release date:2004-11-09
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1Y6Z
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MIDDLE DOMAIN OF PLASMODIUM FALCIPARUM PUTATIVE HEAT SHOCK PROTEIN PF14_0417
Descriptor:heat shock protein, putative
Authors:Lunin, V.V., Botchkareva, E., Loppnau, P., Amani, M., Bray, J., Vedadi, M., Edwards, A., Arrowsmith, C., Sundstrom, M., Bochkarev, A., Hui, R., Plotnikova, O., Structural Genomics Consortium (SGC)
Deposit date:2004-12-07
Release date:2005-02-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1Z6G
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CRYSTAL STRUCTURE OF GUANYLATE KINASE FROM PLASMODIUM FALCIPARUM
Descriptor:guanylate kinase, SULFATE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Mulichak, A.M., Lew, J., Artz, J., Choe, J., Walker, J.R., Zhao, Y., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Hui, R., Gao, M., Structural Genomics Consortium (SGC)
Deposit date:2005-03-22
Release date:2005-04-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1Z7D
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ORNITHINE AMINOTRANSFERASE PY00104 FROM PLASMODIUM YOELII
Descriptor:ornithine aminotransferase
Authors:Walker, J.R., Alam, Z., Amani, M., Lew, J., Wasney, G., Boulanger, K., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Hui, R., Vedadi, M., Structural Genomics Consortium (SGC)
Deposit date:2005-03-24
Release date:2005-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007