Author results

5Z9Y
  • Download 5z9y
  • View 5z9y
Molmil generated image of 5z9y
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THIAZOLE SYNTHASE (THIG) COMPLEXED WITH DXP
Descriptor:Thiazole synthase, 1-DEOXY-D-XYLULOSE-5-PHOSPHATE
Authors:Zhang, J., Zhang, B., Zhao, Y., Yang, X., Huang, M., Cui, P., Zhang, W., Li, J., Zhang, Y.
Deposit date:2018-02-05
Release date:2018-04-11
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Snapshots of catalysis: Structure of covalently bound substrate trapped in Mycobacterium tuberculosis thiazole synthase (ThiG).
Biochem. Biophys. Res. Commun., 497, 2018
4PXZ
  • Download 4pxz
  • View 4pxz
Molmil generated image of 4pxz
CRYSTAL STRUCTURE OF P2Y12 RECEPTOR IN COMPLEX WITH 2MESADP
Descriptor:P2Y purinoceptor 12, Soluble cytochrome b562, 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), ...
Authors:Zhang, J., Zhang, K., Gao, Z.G., Paoletta, S., Zhang, D., Han, G.W., Li, T., Ma, L., Zhang, W., Muller, C.E., Yang, H., Jiang, H., Cherezov, V., Katritch, V., Jacobson, K.A., Stevens, R.C., Wu, B., Zhao, Q., GPCR Network (GPCR)
Deposit date:2014-03-25
Release date:2014-04-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Agonist-bound structure of the human P2Y12 receptor
Nature, 509, 2014
4PY0
  • Download 4py0
  • View 4py0
Molmil generated image of 4py0
CRYSTAL STRUCTURE OF P2Y12 RECEPTOR IN COMPLEX WITH 2MESATP
Descriptor:P2Y purinoceptor 12, Soluble cytochrome b562, 2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate), ...
Authors:Zhang, J., Zhang, K., Gao, Z.G., Paoletta, S., Zhang, D., Han, G.W., Li, T., Ma, L., Zhang, W., Muller, C.E., Yang, H., Jiang, H., Cherezov, V., Katritch, V., Jacobson, K.A., Stevens, R.C., Wu, B., Zhao, Q., GPCR Network (GPCR)
Deposit date:2014-03-25
Release date:2014-04-30
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Agonist-bound structure of the human P2Y12 receptor
Nature, 509, 2014
5D6P
  • Download 5d6p
  • View 5d6p
Molmil generated image of 5d6p
CRYSTAL STRUCTURE OF THE ATP BINDING DOMAIN OF S. AUREUS GYRB COMPLEXED WITH A LIGAND
Descriptor:DNA gyrase subunit B, 1-ethyl-3-[4-(hydroxymethyl)-5-(1H-pyrrol-2-yl)-1,3-thiazol-2-yl]urea, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Zhang, J., Yang, Q., Cross, J.B., Romero, J.A.C., Ryan, M.D., Lippa, B., Dolle, R.E., Andersen, O.A., Barker, J., Cheng, R.K., Kahmann, J., Felicetti, B., Wood, M., Scheich, C.
Deposit date:2015-08-12
Release date:2015-11-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
J.Med.Chem., 58, 2015
5D6Q
  • Download 5d6q
  • View 5d6q
Molmil generated image of 5d6q
CRYSTAL STRUCTURE OF THE ATP BINDING DOMAIN OF S. AUREUS GYRB COMPLEXED WITH A LIGAND
Descriptor:DNA gyrase subunit B, (4S)-2-METHYL-2,4-PENTANEDIOL, 1-ethyl-3-{4-[(E)-2-(pyridin-3-yl)ethenyl]-5-(1H-pyrrol-2-yl)-1,3-thiazol-2-yl}urea, ...
Authors:Zhang, J., Yang, Q., Cross, J.B., Romero, J.A.C., Ryan, M.D., Lippa, B., Dolle, R.E., Andersen, O.A., Barker, J., Cheng, R.K., Kahmann, J., Felicetti, B., Wood, M., Scheich, C.
Deposit date:2015-08-12
Release date:2015-11-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
J.Med.Chem., 58, 2015
5D7C
  • Download 5d7c
  • View 5d7c
Molmil generated image of 5d7c
CRYSTAL STRUCTURE OF THE ATP BINDING DOMAIN OF S. AUREUS GYRB COMPLEXED WITH A LIGAND
Descriptor:DNA gyrase subunit B, (4S)-2-METHYL-2,4-PENTANEDIOL, 1-ethyl-3-[1-(pyridin-2-yl)-6-(pyridin-3-yl)-1H-pyrrolo[3,2-b]pyridin-3-yl]urea, ...
Authors:Zhang, J., Yang, Q., Cross, J.B., Romero, J.A.C., Ryan, M.D., Lippa, B., Dolle, R.E., Andersen, O.A., Barker, J., Cheng, R.K., Kahmann, J., Felicetti, B., Wood, M., Scheich, C.
Deposit date:2015-08-13
Release date:2015-11-25
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
J.Med.Chem., 58, 2015
4G3H
  • Download 4g3h
  • View 4g3h
Molmil generated image of 4g3h
CRYSTAL STRUCTURE OF HELICOBACTER PYLORI ARGINASE
Descriptor:Arginase (RocF), MANGANESE (II) ION
Authors:Zhang, J., Zhang, X., Li, D., Hu, Y., Zou, Q., Wang, D.
Deposit date:2012-07-13
Release date:2012-08-01
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and function studies on Helicobacter pylori arginase
To be Published
1A4F
  • Download 1a4f
  • View 1a4f
Molmil generated image of 1a4f
BAR-HEADED GOOSE HEMOGLOBIN (OXY FORM)
Descriptor:HEMOGLOBIN (ALPHA CHAIN), HEMOGLOBIN (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Zhang, J., Gu, X.
Deposit date:1998-01-29
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of a high oxygen affinity species of haemoglobin (bar-headed goose haemoglobin in the oxy form).
J.Mol.Biol., 255, 1996
3J03
  • Download 3j03
  • View 3j03
Molmil generated image of 3j03
LIDLESS MM-CPN IN THE CLOSED STATE WITH ATP/ALFX
Descriptor:Lidless Mm-cpn
Authors:Zhang, J., Ma, B., DiMaio, F., Douglas, N.R., Joachimiak, L., Baker, D., Frydman, J., Levitt, M., Chiu, W.
Deposit date:2011-02-10
Release date:2011-05-18
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryo-EM structure of a group II chaperonin in the prehydrolysis ATP-bound state leading to lid closure.
Structure, 19, 2011
5ZXL
  • Download 5zxl
  • View 5zxl
Molmil generated image of 5zxl
STRUCTURE OF GLDA FROM E.COLI
Descriptor:Glycerol dehydrogenase, ZINC ION, GLYCEROL, ...
Authors:Zhang, J., Lin, L.
Deposit date:2018-05-21
Release date:2019-03-20
Method:X-RAY DIFFRACTION (2.794 Å)
Cite:Structure of glycerol dehydrogenase (GldA) from Escherichia coli.
Acta Crystallogr F Struct Biol Commun, 75, 2019
4G42
  • Download 4g42
  • View 4g42
Molmil generated image of 4g42
STRUCTURE OF THE CHICKEN MHC CLASS I MOLECULE BF2*0401 COMPLEXED TO PEPITDE P8D
Descriptor:MHC class I alpha chain 2, Beta-2 microglobulin, 8-MERIC PEPTIDE P8D
Authors:Zhang, J., Chen, Y., Qi, J., Gao, F., Liu, J., Kaufman, J., Xia, C., Gao, G.F.
Deposit date:2012-07-16
Release date:2012-11-21
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens.
J.Immunol., 189, 2012
4G43
  • Download 4g43
  • View 4g43
Molmil generated image of 4g43
STRUCTURE OF THE CHICKEN MHC CLASS I MOLECULE BF2*0401 COMPLEXED TO P5E
Descriptor:MHC class I alpha chain 2, Beta-2 microglobulin, 8-MERIC PEPTIDE P5E, ...
Authors:Zhang, J., Chen, Y., Qi, J., Gao, F., Liu, J., Kaufman, J., Xia, C., Gao, G.F.
Deposit date:2012-07-16
Release date:2012-11-21
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens.
J.Immunol., 189, 2012
4TZP
  • Download 4tzp
  • View 4tzp
Molmil generated image of 4tzp
AS GROWN, UNTREATED CO-CRYSTALS OF THE TERNARY COMPLEX CONTAINING A T-BOX STEM I RNA, ITS COGNATE TRNAGLY, AND B. SUBTILIS YBXF PROTEIN
Descriptor:Ribosome-associated protein L7Ae-like, engineered tRNA, glyQ T-box Stem I
Authors:Zhang, J., Ferre-D'Amare, A.R.
Deposit date:2014-07-10
Release date:2014-09-10
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (8.503 Å)
Cite:Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
4TZV
  • Download 4tzv
  • View 4tzv
Molmil generated image of 4tzv
CO-CRYSTALS OF THE TERNARY COMPLEX CONTAINING A T-BOX STEM I RNA, ITS COGNATE TRNAGLY, AND B. SUBTILIS YBXF PROTEIN, TREATED BY REMOVING LITHIUM SULFATE POST CRYSTALLIZATION
Descriptor:Ribosome-associated protein L7Ae-like, engineered tRNA, T-box stem I
Authors:Zhang, J., Ferre-D'Amare, A.R.
Deposit date:2014-07-11
Release date:2014-09-10
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (5.03 Å)
Cite:Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
4TZW
  • Download 4tzw
  • View 4tzw
Molmil generated image of 4tzw
CO-CRYSTALS OF THE TERNARY COMPLEX CONTAINING A T-BOX STEM I RNA, ITS COGNATE TRNAGLY, AND B. SUBTILIS YBXF PROTEIN, TREATED BY REMOVING LITHIUM SULFATE AND REPLACING MG2+ WITH SR2+ POST CRYSTALLIZATION
Descriptor:Ribosome-associated protein L7Ae-like, engineered tRNA, T-box Stem I, ...
Authors:Zhang, J., Ferre-D'Amare, A.R.
Deposit date:2014-07-11
Release date:2014-09-10
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (4.671 Å)
Cite:Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
2M8V
  • Download 2m8v
  • View 2m8v
Molmil generated image of 2m8v
SOLUTION STRUCTURE AND ACTIVITY STUDY OF BOVICIN HJ50, A PARTICULAR TYPE AII LANTIBIOTIC
Descriptor:BovA
Authors:Zhang, J., Feng, Y., Wang, J., Zhong, J.
Deposit date:2013-05-29
Release date:2014-05-21
Method:SOLUTION NMR
Cite:Type AII Lantibiotic Bovicin HJ50 with a Rare Disulfide Bond: Structure, Structure-Activity Relationships and Mode of Action
Biochem.J., 2014
2NWM
  • Download 2nwm
  • View 2nwm
Molmil generated image of 2nwm
SOLUTION STRUCTURE OF THE FIRST SH3 DOMAIN OF HUMAN VINEXIN AND ITS INTERACTION WITH THE PEPTIDES FROM VINCULIN
Descriptor:Vinexin
Authors:Zhang, J., Yao, B., Wu, J., Shi, Y.
Deposit date:2006-11-15
Release date:2007-04-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the first SH3 domain of human vinexin and its interaction with vinculin peptides
Biochem.Biophys.Res.Commun., 357, 2007
3IYF
  • Download 3iyf
  • View 3iyf
Molmil generated image of 3iyf
ATOMIC MODEL OF THE LIDLESS MM-CPN IN THE OPEN STATE
Descriptor:Chaperonin
Authors:Zhang, J., Baker, M.L., Schroeder, G., Douglas, N.R., Reissmann, S., Jakana, J., Dougherty, M., Fu, C.J., Levitt, M., Ludtke, S.J., Frydman, J., Chiu, W.
Deposit date:2009-10-23
Release date:2010-02-02
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Mechanism of folding chamber closure in a group II chaperonin
Nature, 463, 2010
3J02
  • Download 3j02
  • View 3j02
Molmil generated image of 3j02
LIDLESS D386A MM-CPN IN THE PRE-HYDROLYSIS ATP-BOUND STATE
Descriptor:Lidless D386A Mm-cpn variant
Authors:Zhang, J., Ma, B., DiMaio, F., Douglas, N.R., Joachimiak, L., Baker, D., Frydman, J., Levitt, M., Chiu, W.
Deposit date:2011-02-10
Release date:2011-05-18
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Cryo-EM structure of a group II chaperonin in the prehydrolysis ATP-bound state leading to lid closure.
Structure, 19, 2011
3LOS
  • Download 3los
  • View 3los
Molmil generated image of 3los
ATOMIC MODEL OF MM-CPN IN THE CLOSED STATE
Descriptor:Chaperonin
Authors:Zhang, J., Baker, M.L., Schroeder, G., Douglas, N.R., Reissmann, S., Jakana, J., Dougherty, M., Fu, C.J., Levitt, M., Ludtke, S.J., Frydman, J., Chiu, W.
Deposit date:2010-02-04
Release date:2010-03-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Mechanism of folding chamber closure in a group II chaperonin
Nature, 463, 2010
3UIT
  • Download 3uit
  • View 3uit
Molmil generated image of 3uit
OVERALL STRUCTURE OF PATJ/PALS1/MALS COMPLEX
Descriptor:InaD-like protein, MAGUK p55 subfamily member 5, Protein lin-7 homolog B, ...
Authors:Zhang, J., Yang, X., Long, J., Shen, Y.
Deposit date:2011-11-06
Release date:2012-02-22
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of an L27 domain heterotrimer from cell polarity complex Patj/Pals1/Mals2 reveals mutually independent L27 domain assembly mode
J.Biol.Chem., 287, 2012
4E0R
  • Download 4e0r
  • View 4e0r
Molmil generated image of 4e0r
STRUCTURE OF THE CHICKEN MHC CLASS I MOLECULE BF2*0401
Descriptor:MHC class I alpha chain 2, Beta-2 microglobulin, 8-MERIC PEPTIDE (FUS/TLS)
Authors:Zhang, J., Chen, Y., Qi, J., Gao, F., Kaufman, J., Xia, C., Gao, G.F.
Deposit date:2012-03-05
Release date:2012-11-21
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens.
J.Immunol., 189, 2012
5D7D
  • Download 5d7d
  • View 5d7d
Molmil generated image of 5d7d
CRYSTAL STRUCTURE OF THE ATP BINDING DOMAIN OF S. AUREUS GYRB COMPLEXED WITH A LIGAND
Descriptor:DNA gyrase subunit B, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ...
Authors:Zhang, J., Yang, Q., Cross, J.B., Romero, J.A.C., Ryan, M.D., Lippa, B., Dolle, R.E., Andersen, O.A., Barker, J., Cheng, R.K., Kahmann, J., Felicetti, B., Wood, M., Scheich, C.
Deposit date:2015-08-13
Release date:2015-11-11
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors.
Acs Med.Chem.Lett., 6, 2015
5D7R
  • Download 5d7r
  • View 5d7r
Molmil generated image of 5d7r
CRYSTAL STRUCTURE OF THE ATP BINDING DOMAIN OF S. AUREUS GYRB COMPLEXED WITH A LIGAND
Descriptor:DNA gyrase subunit B, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Zhang, J., Yang, Q., Cross, J.B., Romero, J.A.C., Ryan, M.D., Lippa, B., Dolle, R.E., Andersen, O.A., Barker, J., Cheng, R.K., Kahmann, J., Felicetti, B., Wood, M., Scheich, C.
Deposit date:2015-08-14
Release date:2015-11-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors.
Acs Med.Chem.Lett., 6, 2015
5JR9
  • Download 5jr9
  • View 5jr9
Molmil generated image of 5jr9
CRYSTAL STRUCTURE OF APO-NEC3PO
Descriptor:NEQ131
Authors:Zhang, J., Gan, J.
Deposit date:2016-05-06
Release date:2016-09-28
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for single-stranded RNA recognition and cleavage by C3PO
Nucleic Acids Res., 44, 2016