Author results

5DAT
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COMPLEX OF YEAST 80S RIBOSOME WITH HYPUSINE-CONTAINING EIF5A
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Melnikov, S., Mailliot, J., Shin, B.-S., Rigger, L., Yusupova, G., Micura, R., Dever, T.E., Yusupov, M.
Deposit date:2015-08-20
Release date:2016-08-31
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
4V4P
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CRYSTAL STRUCTURE OF 70S RIBOSOME WITH THRS OPERATOR AND TRNAS.
Descriptor:5S ribosomal RNA, 23S ribosomal RNA, 50S ribosomal protein L1, ...
Authors:Jenner, L., Romby, P., Rees, B., Schulze-Briese, C., Springer, M., Ehresmann, C., Ehresmann, B., Moras, D., Yusupova, G., Yusupov, M.
Deposit date:2005-01-19
Release date:2014-07-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Translational operator of mRNA on the ribosome: how repressor proteins exclude ribosome binding.
Science, 308, 2005
5MEI
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CRYSTAL STRUCTURE OF AGELASTATIN A BOUND TO THE 80S RIBOSOME
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:McClary, B., Zinshteyn, B., Meyer, M., Jouanneau, M., Pellegrino, S., Yusupova, G., Schuller, A., Reyes, J.C.P., Lu, J., Luo, C., Dang, Y., Romo, D., Yusupov, M., Green, R., Liu, J.O.
Deposit date:2016-11-15
Release date:2017-06-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A.
Cell Chem Biol, 24, 2017
5NDG
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CRYSTAL STRUCTURE OF GENETICIN (G418) BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Prokhorova, I., Djumagulov, M., Urzhumtsev, A., Yusupov, M., Yusupova, G.
Deposit date:2017-03-08
Release date:2017-12-13
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NDJ
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE TC007 IN COMPLEX WITH 70S RIBOSOME FROM THERMUS THERMOPHILUS, THREE TRNAS AND MRNA (SOAKING)
Descriptor:16S ribosomal RNA, 50S ribosomal protein L18, 50S ribosomal protein L23, ...
Authors:Prokhorova, I., Djumagulov, M., Urzhumtsev, A., Yusupov, M., Yusupova, G.
Deposit date:2017-03-08
Release date:2018-05-02
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NDK
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE TC007 CO-CRYSTALLIZED WITH 70S RIBOSOME FROM THERMUS THERMOPHILUS, THREE TRNAS AND MRNA
Descriptor:16S ribosomal RNA, 50S ribosomal protein L18, 50S ribosomal protein L23, ...
Authors:Prokhorova, I., Djumagulov, M., Urzhumtsev, A., Yusupov, M., Yusupova, G.
Deposit date:2017-03-08
Release date:2017-12-13
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NDV
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CRYSTAL STRUCTURE OF PAROMOMYCIN BOUND TO THE YEAST 80S RIBOSOME
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Prokhorova, I., Djumagulov, M., Urzhumtsev, A., Yusupov, M., Yusupova, G.
Deposit date:2017-03-09
Release date:2017-12-13
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NDW
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE TC007 BOUND TO THE YEAST 80S RIBOSOME
Descriptor:25S ribosomal RNA, 18S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Prokhorova, I., Djumagulov, M., Urzhumtsev, A., Yusupov, M., Yusupova, G.
Deposit date:2017-03-09
Release date:2017-12-13
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5OBM
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CRYSTAL STRUCTURE OF GENTAMICIN BOUND TO THE YEAST 80S RIBOSOME
Descriptor:25S ribosomal RNA, 5S Ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Prokhorova, I., Djumagulov, M., Urzhumtsev, A., Yusupov, M., Yusupova, G.
Deposit date:2017-06-28
Release date:2017-12-13
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5ON6
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CRYSTAL STRUCTURE OF HAEMANTHAMINE BOUND TO THE 80S RIBOSOME
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Pellegrino, S., Meyer, M., Yusupova, G., Yusupov, M.
Deposit date:2017-08-03
Release date:2018-02-28
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (3.100002 Å)
Cite:The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth.
Structure, 26, 2018
5TBW
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CRYSTAL STRUCTURE OF CHLOROLISSOCLIMIDE BOUND TO THE YEAST 80S RIBOSOME
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Konst, Z.A., Szklarski, A.R., Pellegrino, S., Michalak, S.E., Meyer, M., Zanette, C., Cencic, R., Nam, S., Horne, D.A., Pelletier, J., Mobley, D.L., Yusupova, G., Yusupov, M., Vanderwal, C.D.
Deposit date:2016-09-13
Release date:2017-07-26
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides.
Nat Chem, 9, 2017
6HHQ
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CRYSTAL STRUCTURE OF COMPOUND C45 BOUND TO THE YEAST 80S RIBOSOME
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Pellegrino, S., Vanderwal, C.D., Yusupov, M.
Deposit date:2018-08-28
Release date:2019-02-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome
To Be Published
1Y99
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HIV-1 SUBTYPE A DIS RNA DUPLEX
Descriptor:5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', MAGNESIUM ION
Authors:Ennifar, E., Yusupov, M., Walter, P., Marquet, R., Ehresmann, B., Ehresmann, C., Dumas, P.
Deposit date:2004-12-15
Release date:2004-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of the dimerization initiation site of genomic HIV-1 RNA reveals an extended duplex with two adenine bulges
Structure Fold.Des., 7, 1999
2VAZ
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MODEL OF THE S15-MRNA COMPLEX FITTED INTO THE CRYO-EM MAP OF THE 70S ENTRAPMENT COMPLEX.
Descriptor:RPSO MRNA OPERATOR, 30S RIBOSOMAL PROTEIN S15
Authors:Marzi, S., Myasnikov, A.G., Serganov, A., Ehresmann, C., Romby, P., Yusupov, M., Klaholz, B.P.
Deposit date:2007-09-05
Release date:2007-10-02
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Structured Mrnas Regulate Translation Initiation by Binding to the Platform of the Ribosome.
Cell(Cambridge,Mass.), 130, 2007
462D
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CRYSTAL STRUCTURE OF THE HIV-1 GENOMIC RNA DIMERIZATION INITIATION SITE
Descriptor:RNA (5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G) -3'), MAGNESIUM ION
Authors:Ennifar, E., Yusupov, M., Walter, P., Marquet, R., Ehresmann, C., Ehresmann, B., Dumas, P.
Deposit date:1999-03-18
Release date:1999-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of the dimerization initiation site of genomic HIV-1 RNA reveals an extended duplex with two adenine bulges.
Structure Fold.Des., 7, 1999
4U3M
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CRYSTAL STRUCTURE OF ANISOMYCIN BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S rRNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-22
Release date:2014-10-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U3N
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CRYSTAL STRUCTURE OF CCA TRINUCLEOTIDE BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-22
Release date:2014-10-22
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U3U
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CRYSTAL STRUCTURE OF CYCLOHEXIMIDE BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-22
Release date:2014-10-22
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U4N
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CRYSTAL STRUCTURE OF EDEINE BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2016-01-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U4O
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CRYSTAL STRUCTURE OF GENETICIN BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U4Q
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CRYSTAL STRUCTURE OF HOMOHARRINGTONINE BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U4R
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CRYSTAL STRUCTURE OF LACTIMIDOMYCIN BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U4U
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CRYSTAL STRUCTURE OF LYCORINE BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U4Y
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CRYSTAL STRUCTURE OF PACTAMYCIN BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U4Z
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CRYSTAL STRUCTURE OF PHYLLANTHOSIDE BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
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