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6PTO
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BU of 6pto by Molmil
Structure of Ctf4 trimer in complex with three CMG helicases
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA polymerase alpha-binding protein, ...
Authors:Yuan, Z, Georgescu, R, Bai, L, Santos, R, Donnell, M, Li, H.
Deposit date:2019-07-16
Release date:2019-11-20
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Ctf4 organizes sister replisomes and Pol alpha into a replication factory.
Elife, 8, 2019
6PTJ
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BU of 6ptj by Molmil
Structure of Ctf4 trimer in complex with one CMG helicase
Descriptor: Cell division control protein 45, DNA polymerase alpha-binding protein, DNA replication complex GINS protein PSF1, ...
Authors:Yuan, Z, Georgescu, R, Bai, L, Santos, R, Donnell, M, Li, H.
Deposit date:2019-07-15
Release date:2019-11-20
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ctf4 organizes sister replisomes and Pol alpha into a replication factory.
Elife, 8, 2019
6PTN
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BU of 6ptn by Molmil
Structure of Ctf4 trimer in complex with two CMG helicases
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA polymerase alpha-binding protein, ...
Authors:Yuan, Z, Georgescu, R, Bai, L, Santos, R, Donnell, M, Li, H.
Deposit date:2019-07-16
Release date:2019-11-20
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Ctf4 organizes sister replisomes and Pol alpha into a replication factory.
Elife, 8, 2019
6WGI
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BU of 6wgi by Molmil
Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at 10.5 A resolution
Descriptor: Cell division control protein 6, Cell division cycle protein CDT1, DNA (34-MER), ...
Authors:Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C.
Deposit date:2020-04-05
Release date:2020-07-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WGG
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BU of 6wgg by Molmil
Atomic model of pre-insertion mutant OCCM-DNA complex(ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation)
Descriptor: Cell division control protein 6, Cell division cycle protein CDT1, DNA (41-MER), ...
Authors:Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C.
Deposit date:2020-04-05
Release date:2020-07-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (8.1 Å)
Cite:Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WGC
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BU of 6wgc by Molmil
Atomic model of semi-attached mutant OCCM-DNA complex (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation)
Descriptor: Cell division control protein 6, DNA (41-MER), DNA replication licensing factor MCM3, ...
Authors:Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C.
Deposit date:2020-04-05
Release date:2020-07-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WJV
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BU of 6wjv by Molmil
Structure of the Saccharomyces cerevisiae polymerase epsilon holoenzyme
Descriptor: DNA polymerase epsilon catalytic subunit A, DNA polymerase epsilon subunit B, DNA polymerase epsilon subunit C, ...
Authors:Yuan, Z, Georgescu, R, Schauer, G.D, O'Donnell, M, Li, H.
Deposit date:2020-04-14
Release date:2020-07-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the polymerase epsilon holoenzyme and atomic model of the leading strand replisome.
Nat Commun, 11, 2020
6WGF
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BU of 6wgf by Molmil
Atomic model of mutant Mcm2-7 hexamer with Mcm6 WHD truncation
Descriptor: DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, ...
Authors:Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C.
Deposit date:2020-04-05
Release date:2020-07-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
8FOH
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BU of 8foh by Molmil
Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the RNA synthesis state
Descriptor: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Yuan, Z, Georgescu, R, Li, H, O'Donnell, M.
Deposit date:2022-12-30
Release date:2023-05-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase.
Nat Commun, 14, 2023
8FOJ
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BU of 8foj by Molmil
Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the post RNA handoff state
Descriptor: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Yuan, Z, Georgescu, R, Li, H, O'Donnell, M.
Deposit date:2022-12-30
Release date:2023-05-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase.
Nat Commun, 14, 2023
8FOD
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BU of 8fod by Molmil
Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in Apo state conformation II
Descriptor: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Yuan, Z, Georgescu, R, Li, H, O'Donnell, M.
Deposit date:2022-12-30
Release date:2023-05-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase.
Nat Commun, 14, 2023
8FOE
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BU of 8foe by Molmil
Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex bound to a template DNA
Descriptor: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Yuan, Z, Georgescu, R, Li, H, O'Donnell, M.
Deposit date:2022-12-30
Release date:2023-05-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase.
Nat Commun, 14, 2023
8FOK
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BU of 8fok by Molmil
Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the DNA elongation state
Descriptor: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Yuan, Z, Georgescu, R, Li, H, O'Donnell, M.
Deposit date:2022-12-30
Release date:2023-05-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase.
Nat Commun, 14, 2023
8FOC
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BU of 8foc by Molmil
Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase in Apo state conformation I
Descriptor: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Yuan, Z, Georgescu, R, Li, H, O'Donnell, M.
Deposit date:2022-12-30
Release date:2023-05-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase.
Nat Commun, 14, 2023
6U0M
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BU of 6u0m by Molmil
Structure of the S. cerevisiae replicative helicase CMG in complex with a forked DNA
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA (15-MER), ...
Authors:Yuan, Z, Georgescu, R, Bai, L, Zhang, D, O'Donnell, M, Li, H.
Deposit date:2019-08-14
Release date:2020-03-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:DNA unwinding mechanism of a eukaryotic replicative CMG helicase.
Nat Commun, 11, 2020
5V8F
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BU of 5v8f by Molmil
Structural basis of MCM2-7 replicative helicase loading by ORC-Cdc6 and Cdt1
Descriptor: Cell division control protein 6, Cell division cycle protein CDT1, DNA (39-MER), ...
Authors:Yuan, Z, Riera, A, Bai, L, Sun, J, Spanos, C, Chen, Z.A, Barbon, M, Rappsilber, J, Stillman, B, Speck, C, Li, H.
Deposit date:2017-03-21
Release date:2017-05-10
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.
Nat. Struct. Mol. Biol., 24, 2017
6DKS
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BU of 6dks by Molmil
Structure of the Rbpj-SHARP-DNA Repressor Complex
Descriptor: DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), Maltose/maltodextrin-binding periplasmic protein, ...
Authors:Kovall, R.A, VanderWielen, B.D, Yuan, Z.
Deposit date:2018-05-30
Release date:2019-01-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structural and Functional Studies of the RBPJ-SHARP Complex Reveal a Conserved Corepressor Binding Site.
Cell Rep, 26, 2019
3VZ2
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BU of 3vz2 by Molmil
Structural insights into substrate and cofactor selection by sp2771
Descriptor: Succinate-semialdehyde dehydrogenase
Authors:Yuan, Y.A, Yuan, Z, Yin, B, Wei, D.
Deposit date:2012-10-09
Release date:2013-10-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for cofactor and substrate selection by cyanobacterium succinic semialdehyde dehydrogenase
J.Struct.Biol., 182, 2013
3VZ1
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BU of 3vz1 by Molmil
Structural insights into substrate and cofactor selelction by sp2771
Descriptor: Succinate-semialdehyde dehydrogenase
Authors:Yuan, Y.A, Yuan, Z, Yin, B, Wei, D.
Deposit date:2012-10-09
Release date:2013-07-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for cofactor and substrate selection by cyanobacterium succinic semialdehyde dehydrogenase
J.Struct.Biol., 182, 2013
3VZ3
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BU of 3vz3 by Molmil
Structural insights into substrate and cofactor selection by sp2771
Descriptor: 4-oxobutanoic acid, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Succinate-semialdehyde dehydrogenase
Authors:Yuan, Y.A, Yuan, Z, Yin, B, Wei, D.
Deposit date:2012-10-09
Release date:2013-07-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural basis for cofactor and substrate selection by cyanobacterium succinic semialdehyde dehydrogenase
J.Struct.Biol., 182, 2013
3VZ0
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BU of 3vz0 by Molmil
Structural insights into cofactor and substrate selection by Gox0499
Descriptor: NONAETHYLENE GLYCOL, Putative NAD-dependent aldehyde dehydrogenase
Authors:Yuan, Y.A, Yuan, Z, Yin, B, Wei, D.
Deposit date:2012-10-09
Release date:2013-07-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for cofactor and substrate selection by cyanobacterium succinic semialdehyde dehydrogenase
J.Struct.Biol., 182, 2013
5HHA
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BU of 5hha by Molmil
Structure of PvdO from Pseudomonas aeruginosa
Descriptor: CALCIUM ION, PvdO
Authors:Bai, G, Yuan, Z, Shang, G, Xia, H, Gu, L.
Deposit date:2016-01-10
Release date:2017-01-18
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Crystal structure of Chromophore maturation protein from Pseudomonas aeruginosa
To Be Published
3JC7
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BU of 3jc7 by Molmil
Structure of the eukaryotic replicative CMG helicase and pumpjack motion
Descriptor: Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ...
Authors:Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E.
Deposit date:2015-11-24
Release date:2016-02-10
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
Nat.Struct.Mol.Biol., 23, 2016
3JC5
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BU of 3jc5 by Molmil
Structure of the eukaryotic replicative CMG helicase and pumpjack motion
Descriptor: Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ...
Authors:Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E.
Deposit date:2015-11-24
Release date:2016-02-10
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
Nat.Struct.Mol.Biol., 23, 2016
3JC6
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BU of 3jc6 by Molmil
Structure of the eukaryotic replicative CMG helicase and pumpjack motion
Descriptor: Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ...
Authors:Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E.
Deposit date:2015-11-24
Release date:2016-02-10
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
Nat.Struct.Mol.Biol., 23, 2016

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PDB entries from 2024-03-27

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