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1QTR
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CRYSTAL STRUCTURE ANALYSIS OF THE PROLYL AMINOPEPTIDASE FROM SERRATIA MARCESCENS
分子名称:PROLYL AMINOPEPTIDASE
著者Yoshimoto, T., Kabashima, T., Uchikawa, K., Inoue, T., Tanaka, N.
登録日1999-06-28
公開日1999-07-07
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Crystal structure of prolyl aminopeptidase from Serratia marcescens.
J.Biochem.(Tokyo), 126, 1999
1J2T
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CREATININASE MN
分子名称:creatinine amidohydrolase, ZINC ION, MANGANESE (II) ION, ...
著者Yoshimoto, T., Tanaka, N., Kanada, N., Inoue, T., Nakajima, Y., Haratake, M., Nakamura, K.T., Xu, Y., Ito, K.
登録日2003-01-11
公開日2004-01-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of creatininase reveal the substrate binding site and provide an insight into the catalytic mechanism
J.Mol.Biol., 337, 2004
1J2U
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CREATININASE ZN
分子名称:creatinine amidohydrolase, ZINC ION, SULFATE ION
著者Yoshimoto, T., Tanaka, N., Kanada, N., Inoue, T., Nakajima, Y., Haratake, M., Nakamura, K.T., Xu, Y., Ito, K.
登録日2003-01-11
公開日2004-01-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structures of creatininase reveal the substrate binding site and provide an insight into the catalytic mechanism
J.Mol.Biol., 337, 2004
1V7Z
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CREATININASE-PRODUCT COMPLEX
分子名称:creatinine amidohydrolase, MANGANESE (II) ION, ZINC ION, ...
著者Yoshimoto, T., Tanaka, N., Kanada, N., Inoue, T., Nakajima, Y., Haratake, M., Nakamura, K.T., Xu, Y., Ito, K.
登録日2003-12-26
公開日2004-01-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of creatininase reveal the substrate binding site and provide an insight into the catalytic mechanism
J.Mol.Biol., 337, 2004
1WM1
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CRYSTAL STRUCTURE OF PROLYL AMINOPEPTIDASE, COMPLEX WITH PRO-TBODA
分子名称:Proline iminopeptidase, (5-TERT-BUTYL-1,3,4-OXADIAZOL-2-YL)[(2R)-PYRROLIDIN-2-YL]METHANONE
著者Nakajima, Y., Inoue, T., Ito, K., Tozaka, T., Hatakeyama, S., Tanaka, N., Nakamura, K.T., Yoshimoto, T.
登録日2004-07-01
公開日2004-07-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Novel inhibitor for prolyl aminopeptidase from Serratia marcescens and studies on the mechanism of substrate recognition of the enzyme using the inhibitor
ARCH.BIOCHEM.BIOPHYS., 416, 2003
1AUG
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CRYSTAL STRUCTURE OF THE PYROGLUTAMYL PEPTIDASE I FROM BACILLUS AMYLOLIQUEFACIENS
分子名称:PYROGLUTAMYL PEPTIDASE-1
著者Odagaki, Y., Hayashi, A., Okada, K., Hirotsu, K., Kabashima, T., Ito, K., Yoshimoto, T., Tsuru, D., Sato, M., Clardy, J.
登録日1997-08-26
公開日1999-03-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of pyroglutamyl peptidase I from Bacillus amyloliquefaciens reveals a new structure for a cysteine protease.
Structure Fold.Des., 7, 1999
2D5L
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CRYSTAL STRUCTURE OF PROLYL TRIPEPTIDYL AMINOPEPTIDASE FROM PORPHYROMONAS GINGIVALIS
分子名称:dipeptidyl aminopeptidase IV, putative, SULFATE ION
著者Nakajima, Y., Ito, K., Xu, Y., Yamada, N., Onohara, Y., Yoshimoto, T.
登録日2005-11-02
公開日2006-09-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure and Mechanism of Tripeptidyl Activity of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis
J.Mol.Biol., 362, 2006
2DCM
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THE CRYSTAL STRUCTURE OF S603A MUTATED PROLYL TRIPEPTIDYL AMINOPEPTIDASE COMPLEXED WITH SUBSTRATE
分子名称:dipeptidyl aminopeptidase IV, putative, GLYCYLALANYL-N-2-NAPHTHYL-L-PROLINEAMIDE
著者Nakajima, Y., Ito, K., Xu, Y., Yamada, N., Onohara, Y., Yoshimoto, T.
登録日2006-01-09
公開日2006-09-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure and Mechanism of Tripeptidyl Activity of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis
J.Mol.Biol., 362, 2006
2ECF
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CRYSTAL STRUCTURE OF DIPEPTIDYL AMINOPEPTIDASE IV FROM STENOTROPHOMONAS MALTOPHILIA
分子名称:Dipeptidyl peptidase IV
著者Nakajima, Y., Ito, K., Yoshimoto, T.
登録日2007-02-13
公開日2008-02-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Dipeptidyl aminopeptidase IV from Stenotrophomonas maltophilia exhibits activity against a substrate containing a 4-hydroxyproline residue
J.Bacteriol., 190, 2008
2DQ6
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CRYSTAL STRUCTURE OF AMINOPEPTIDASE N FROM ESCHERICHIA COLI
分子名称:Aminopeptidase N, ZINC ION, SULFATE ION
著者Nakajima, Y., Onohara, Y., Ito, K., Yoshimoto, T.
登録日2006-05-22
公開日2006-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Aminopeptidase N (proteobacteria alanyl aminopeptidase) from Escherichia coli: Crystal structure and conformational change of the methionine 260 residue involved in substrate recognition
J.Biol.Chem., 281, 2006
2DQM
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CRYSTAL STRUCTURE OF AMINOPEPTIDASE N COMPLEXED WITH BESTATIN
分子名称:Aminopeptidase N, ZINC ION, SULFATE ION, ...
著者Onohara, Y., Nakajima, Y., Ito, K., Yoshimoto, T.
登録日2006-05-29
公開日2006-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Aminopeptidase N (proteobacteria alanyl aminopeptidase) from Escherichia coli: Crystal structure and conformational change of the methionine 260 residue involved in substrate recognition
J.Biol.Chem., 281, 2006
2EEP
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PROLYL TRIPEPTIDYL AMINOPEPTIDASE COMPLEXED WITH AN INHIBITOR
分子名称:Dipeptidyl aminopeptidase IV, putative, SULFATE ION, ...
著者Xu, Y., Nakajima, Y., Ito, K., Yoshimoto, T.
登録日2007-02-16
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism
J.Mol.Biol., 375, 2008
2Z3W
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PROLYL TRIPEPTIDYL AMINOPEPTIDASE MUTANT E636A
分子名称:Dipeptidyl aminopeptidase IV, SULFATE ION, GLYCEROL
著者Xu, Y., Nakajima, Y., Ito, K., Yoshimoto, T.
登録日2007-06-07
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism
J.Mol.Biol., 375, 2008
2Z3Z
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PROLYL TRIPEPTIDYL AMINOPEPTIDASE MUTANT E636A COMPLEXD WITH AN INHIBITOR
分子名称:Dipeptidyl aminopeptidase IV, SULFATE ION, [(2R)-1-(L-ALANYL-L-ISOLEUCYL)PYRROLIDIN-2-YL]BORONIC ACID
著者Xu, Y., Nakajima, Y., Ito, K., Yoshimoto, T.
登録日2007-06-09
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism
J.Mol.Biol., 375, 2008
1KOL
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CRYSTAL STRUCTURE OF FORMALDEHYDE DEHYDROGENASE
分子名称:formaldehyde dehydrogenase, ZINC ION, SULFATE ION, ...
著者Tanaka, N., Kusakabe, Y., Ito, K., Yoshimoto, T., Nakamura, K.T.
登録日2001-12-21
公開日2002-12-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal Structure of Formaldehyde Dehydrogenase from Pseudomonas putida: the Structural Origin of the Tightly Bound Cofactor in Nicotinoprotein Dehydrogenases
J.mol.biol., 324, 2002
1WMB
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CRYSTAL STRUCTURE OF NAD DEPENDENT D-3-HYDROXYBUTYLATE DEHYDROGENASE
分子名称:D(-)-3-hydroxybutyrate dehydrogenase, MAGNESIUM ION, CACODYLATE ION
著者Ito, K., Nakajima, Y., Ichihara, E., Ogawa, K., Yoshimoto, T.
登録日2004-07-06
公開日2005-09-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献d-3-Hydroxybutyrate Dehydrogenase from Pseudomonas fragi: Molecular Cloning of the Enzyme Gene and Crystal Structure of the Enzyme
J.Mol.Biol., 355, 2006
1X1T
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CRYSTAL STRUCTURE OF D-3-HYDROXYBUTYRATE DEHYDROGENASE FROM PSEUDOMONAS FRAGI COMPLEXED WITH NAD+
分子名称:D(-)-3-hydroxybutyrate dehydrogenase, MAGNESIUM ION, CACODYLATE ION, ...
著者Ito, K., Nakajima, Y., Ichihara, E., Ogawa, K., Yoshimoto, T.
登録日2005-04-13
公開日2006-01-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献d-3-Hydroxybutyrate Dehydrogenase from Pseudomonas fragi: Molecular Cloning of the Enzyme Gene and Crystal Structure of the Enzyme
J.Mol.Biol., 355, 2006
1X2B
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THE CRYSTAL STRUCTURE OF PROLYL AMINOPEPTIDASE COMPLEXED WITH SAR-TBODA
分子名称:Proline iminopeptidase, 1-(5-TERT-BUTYL-1,3,4-OXADIAZOL-2-YL)-2-(METHYLAMINO)ETHANONE
著者Nakajima, Y., Ito, K., Sakata, M., Xu, Y., Matsubara, F., Hatakeyama, S., Yoshimoto, T.
登録日2005-04-22
公開日2006-05-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Unusual extra space at the active site and high activity for acetylated hydroxyproline of prolyl aminopeptidase from Serratia marcescens
J.Bacteriol., 188, 2006
1X2E
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THE CRYSTAL STRUCTURE OF PROLYL AMINOPEPTIDASE COMPLEXED WITH ALA-TBODA
分子名称:Proline iminopeptidase, (2S)-2-AMINO-1-(5-TERT-BUTYL-1,3,4-OXADIAZOL-2-YL)PROPAN-1-ONE
著者Nakajima, Y., Ito, K., Sakata, M., Xu, Y., Matsubara, F., Hatakeyama, S., Yoshimoto, T.
登録日2005-04-22
公開日2006-05-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Unusual extra space at the active site and high activity for acetylated hydroxyproline of prolyl aminopeptidase from Serratia marcescens
J.Bacteriol., 188, 2006
2ZTL
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CLOSED CONFORMATION OF D-3-HYDROXYBUTYRATE DEHYDROGENASE COMPLEXED WITH NAD+ AND L-3-HYDROXYBUTYRATE
分子名称:D(-)-3-hydroxybutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, (3S)-3-HYDROXYBUTANOIC ACID, ...
著者Nakashima, K., Nakajima, Y., Ito, K., Yoshimoto, T.
登録日2008-10-07
公開日2009-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Closed complex of the D-3-hydroxybutyrate dehydrogenase induced by an enantiomeric competitive inhibitor.
J.Biochem., 145, 2009
2ZTM
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T190S MUTANT OF D-3-HYDROXYBUTYRATE DEHYDROGENASE
分子名称:D(-)-3-hydroxybutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, (3S)-3-HYDROXYBUTANOIC ACID, ...
著者Nakashima, K., Nakajima, Y., Ito, K., Yoshimoto, T.
登録日2008-10-07
公開日2009-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Closed complex of the D-3-hydroxybutyrate dehydrogenase induced by an enantiomeric competitive inhibitor.
J.Biochem., 145, 2009
2ZTU
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T190A MUTANT OF D-3-HYDROXYBUTYRATE DEHYDROGENASE COMPLEXED WITH NAD+
分子名称:D(-)-3-hydroxybutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, MAGNESIUM ION
著者Nakashima, K., Nakajima, Y., Ito, K., Yoshimoto, T.
登録日2008-10-09
公開日2009-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Closed complex of the D-3-hydroxybutyrate dehydrogenase induced by an enantiomeric competitive inhibitor.
J.Biochem., 145, 2009
2ZTV
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THE BINARY COMPLEX OF D-3-HYDROXYBUTYRATE DEHYDROGENASE WITH NAD+
分子名称:D(-)-3-hydroxybutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, MAGNESIUM ION, ...
著者Nakashima, K., Nakajima, Y., Ito, K., Yoshimoto, T.
登録日2008-10-09
公開日2009-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Closed complex of the D-3-hydroxybutyrate dehydrogenase induced by an enantiomeric competitive inhibitor.
J.Biochem., 145, 2009
2ZXG
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AMINOPEPTIDASE N COMPLEXED WITH THE AMINOPHOSPHINIC INHIBITOR OF PL250, A TRANSITION STATE ANALOGUE
分子名称:Aminopeptidase N, ZINC ION, N-{(2S)-3-[(1R)-1-aminoethyl](hydroxy)phosphoryl-2-benzylpropanoyl}-L-phenylalanine, ...
著者Nakajima, Y., Ito, K., Yoshimoto, T.
登録日2008-12-24
公開日2009-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of aminopeptidase N from Escherichia coli complexed with the transition-state analogue aminophosphinic inhibitor PL250
Acta Crystallogr.,Sect.D, 65, 2009
3A6D
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CREATININASE COMPLEXED WITH 1-METHYLGUANIDINE
分子名称:Creatinine amidohydrolase, MANGANESE (II) ION, ZINC ION, ...
著者Nakajima, Y., Yamashita, K., Ito, K., Yoshimoto, T.
登録日2009-08-31
公開日2010-02-09
最終更新日2014-01-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Substitution of Glu122 by glutamine revealed the function of the second water molecule as a proton donor in the binuclear metal enzyme creatininase
J.Mol.Biol., 396, 2010
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