Author results

4RAP
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CRYSTAL STRUCTURE OF BACTERIAL IRON-CONTAINING DODECAMERIC GLYCOSYLTRANSFERASE TIBC FROM ENTEROTOXIGENIC E.COLI H10407
Descriptor:Glycosyltransferase TibC, FE (III) ION, 1,2-ETHANEDIOL
Authors:Yao, Q., Lu, Q., Xu, Y., Shao, F.
Deposit date:2014-09-10
Release date:2014-10-29
Method:X-RAY DIFFRACTION (2.881 Å)
Cite:A structural mechanism for bacterial autotransporter glycosylation by a dodecameric heptosyltransferase family.
Elife, 3, 2014
4RB4
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CRYSTAL STRUCTURE OF DODECAMERIC IRON-CONTAINING HEPTOSYLTRANSFERASE TIBC IN COMPLEX WITH ADP-D-BETA-D-HEPTOSE AT 3.9 ANGSTROM RESOLUTION
Descriptor:Glycosyltransferase tibC, FE (III) ION, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3R,4R,5R,6S)-6-[(1R)-1,2-dihydroxyethyl]-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl dihydrogen diphosphate, ...
Authors:Yao, Q., Lu, Q., Shao, F.
Deposit date:2014-09-12
Release date:2014-11-05
Method:X-RAY DIFFRACTION (3.88 Å)
Cite:A structural mechanism for bacterial autotransporter glycosylation by a dodecameric heptosyltransferase family
Elife, 3, 2014
3EIR
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CRYSTAL STRUCTURE OF CHBP, A CIF HOMOLOGUE FROM BURKHOLDERIA PSEUDOMALLEI
Descriptor:Putative ATP/GTP binding protein
Authors:Yao, Q., Zhu, Y., Shao, F.
Deposit date:2008-09-17
Release date:2009-02-03
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:A bacterial type III effector family uses the papain-like hydrolytic activity to arrest the host cell cycle
Proc.Natl.Acad.Sci.USA, 106, 2009
3EIT
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THE 2.6 ANGSTROM CRYSTAL STRUCTURE OF CHBP, THE CIF HOMOLOGUE FROM BURKHOLDERIA PSEUDOMALLEI
Descriptor:Putative ATP/GTP binding protein
Authors:Yao, Q., Zhu, Y., Shao, F.
Deposit date:2008-09-17
Release date:2009-02-03
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:A bacterial type III effector family uses the papain-like hydrolytic activity to arrest the host cell cycle
Proc.Natl.Acad.Sci.USA, 106, 2009
4HCN
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CRYSTAL STRUCTURE OF BURKHOLDERIA PSEUDOMALLEI EFFECTOR PROTEIN CHBP IN COMPLEX WITH UBIQUITIN
Descriptor:Putative ATP/GTP binding protein, Polyubiquitin, DI(HYDROXYETHYL)ETHER, ...
Authors:Yao, Q., Cui, J., Zhu, Y., Shao, F.
Deposit date:2012-09-30
Release date:2012-11-21
Last modified:2017-03-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4HCP
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CRYSTAL STRUCTURE OF BURKHOLDERIA PSEUDOMALLEI EFFECTOR PROTEIN CHBP IN COMPLEX WITH NEDD8
Descriptor:Putative ATP/GTP binding protein, NEDD8, SULFATE ION, ...
Authors:Yao, Q., Shao, F.
Deposit date:2012-10-01
Release date:2012-11-21
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4R29
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CRYSTAL STRUCTURE OF BACTERIAL CYSTEINE METHYLTRANSFERASE EFFECTOR NLEE
Descriptor:Uncharacterized protein, S-ADENOSYLMETHIONINE, GLYCEROL, ...
Authors:Yao, Q., Chen, J., Hu, L., Zhang, L., Shao, F.
Deposit date:2014-08-11
Release date:2014-12-03
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structure and Specificity of the Bacterial Cysteine Methyltransferase Effector NleE Suggests a Novel Substrate in Human DNA Repair Pathway.
Plos Pathog., 10, 2014
4Q1Q
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CRYSTAL STRUCTURE OF TIBC-CATALYZED HYPER-GLYCOSYLATED TIBA55-350 FRAGMENT
Descriptor:Adhesin/invasin TibA autotransporter, D-glycero-alpha-D-manno-heptopyranose
Authors:Yao, Q., Lu, Q., Shao, F.
Deposit date:2014-04-04
Release date:2014-09-17
Last modified:2014-10-29
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:An iron-containing dodecameric heptosyltransferase family modifies bacterial autotransporters in pathogenesis
Cell Host Microbe, 16, 2014
6MWQ
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SINGLE PARTICLE CRYOEM STRUCTURE OF A DARPIN-ALDOLASE PLATFORM IN COMPLEX WITH GFP
Descriptor:DARPin, Muscle-type aldolase chimeric fusion, Green fluorescent protein
Authors:Weaver, S.J., Yao, Q.
Deposit date:2018-10-30
Release date:2018-11-21
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Fusion of DARPin to aldolase enables visualization of small protein by cryoEM
Biorxiv, 2018
4JVS
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CRYSTAL STRUCTURE OF LEPB GAP DOMAIN FROM LEGIONELLA DRANCOURTII IN COMPLEX WITH RAB1-GDP AND ALF3
Descriptor:Putative uncharacterized protein, Ras-related protein Rab-1A, ACETIC ACID, ...
Authors:Yu, Q., Yao, Q., Wang, D.-C., Shao, F.
Deposit date:2013-03-26
Release date:2013-05-08
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (2.783 Å)
Cite:Structural analyses of Legionella LepB reveal a new GAP fold that catalytically mimics eukaryotic RasGAP
Cell Res., 23, 2013
4JW1
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CRYSTAL STRUCTURE OF N-TERMINAL 618-RESIDUE FRAGMENT OF LEPB FROM LEGIONELLA PNEUMOPHILA
Descriptor:Effector protein B, GLYCEROL, CITRATE ANION
Authors:Hu, L., Yao, Q., Zhu, Y., Shao, F.
Deposit date:2013-03-26
Release date:2013-05-08
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Structural analyses of Legionella LepB reveal a new GAP fold that catalytically mimics eukaryotic RasGAP
Cell Res., 23, 2013
4PKM
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CRYSTAL STRUCTURE OF BACILLUS THURINGIENSIS CRY51AA1 PROTOXIN AT 1.65 ANGSTROMS RESOLUTION
Descriptor:Cry51Aa1, GLYCEROL, SULFATE ION, ...
Authors:Xu, C., Chinte, U., Chen, L., Yao, Q., Zhou, D., Meng, Y., Li, L., Rose, J., Bi, L.J., Yu, Z., Sun, M., Wang, B.C.
Deposit date:2014-05-15
Release date:2015-06-03
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of Cry51Aa1: A potential novel insecticidal aerolysin-type beta-pore-forming toxin from Bacillus thuringiensis.
Biochem.Biophys.Res.Commun., 462, 2015
5HH9
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STRUCTURE OF PVDN FROM PSEUDOMONAS AERUGINOSA
Descriptor:PvdN, PYRIDOXAL-5'-PHOSPHATE
Authors:Xia, H., Bai, G., Liu, S., Li, N., Xu, S., Chen, K., Yao, Q., Gu, L.
Deposit date:2016-01-10
Release date:2017-01-18
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structural and Biochemical Characterization of a Novel L-Cystine Desulfurase involved in the biosynthesis of the major siderophore pyoverdine in Pseudomonas aeruginosa
To Be Published
5JKF
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CRYSTAL STRUCTURE OF ESTERASE E22
Descriptor:Esterase E22
Authors:Zhang, Y., Wang, P., Yao, Q.
Deposit date:2016-04-26
Release date:2017-04-26
Method:X-RAY DIFFRACTION (2.393 Å)
Cite:Structural basis for substrate recognition and catalysis of a novel esterase E22 with a homoserine transacetylase-like fold
To Be Published
5JKJ
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CRYSTAL STRUCTURE OF ESTERASE E22 L374D MUTANT
Descriptor:Esterase E22
Authors:Zhang, Y., Wang, P., Yao, Q.
Deposit date:2016-04-26
Release date:2017-04-26
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for substrate recognition and catalysis of a novel esterase E22 with a homoserine transacetylase-like fold
To Be Published
5YAA
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CRYSTAL STRUCTURE OF MARF1 NYN DOMAIN FROM MUS MUSCULUS
Descriptor:Meiosis regulator and mRNA stability factor 1, GLYCEROL
Authors:Yao, Q.Q., Wu, B.X., Ma, J.B.
Deposit date:2017-08-31
Release date:2018-10-03
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Ribonuclease activity of MARF1 controls oocyte RNA homeostasis and genome integrity in mice.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5YAD
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CRYSTAL STRUCTURE OF MARF1 LOTUS DOMAIN FROM MUS MUSCULUS
Descriptor:Meiosis regulator and mRNA stability factor 1, SULFATE ION, GLYCEROL
Authors:Yao, Q.Q., Wu, B.X., Ma, J.B.
Deposit date:2017-08-31
Release date:2018-10-03
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Ribonuclease activity of MARF1 controls oocyte RNA homeostasis and genome integrity in mice.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5EOB
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CRYSTAL STRUCTURE OF CMET IN COMPLEX WITH NOVEL INHIBITOR
Descriptor:Hepatocyte growth factor receptor, 6-[bis(fluoranyl)-[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl]methyl]quinoline
Authors:Liu, Q., Chen, T., Xu, Y.
Deposit date:2015-11-10
Release date:2016-10-19
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Discovery of 6-(difluoro(6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl)methyl)quinoline as a highly potent and selective c-Met inhibitor
Eur.J.Med.Chem., 116, 2016
5XUN
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CRYSTAL STRUCTURE OF Y145F MUTANT OF KACT
Descriptor:Acetyltransferase, ACETYL COENZYME *A, ACETATE ION
Authors:Qian, H.L., Yao, Q.Q., Gan, J.H., Ou, H.Y.
Deposit date:2017-06-23
Release date:2017-07-19
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification and characterization of acetyltransferase-type toxin-antitoxin locus in Klebsiella pneumoniae
Mol. Microbiol., 108, 2018
6A0X
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CRYSTAL STRUCTURE OF BROADLY NEUTRALIZING ANTIBODY 13D4
Descriptor:Antibody 13D4, Fab Heavy Chain, Fab Light Chain
Authors:Li, S., Li, T.
Deposit date:2018-06-06
Release date:2018-06-20
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the Broad, Antibody-Mediated Neutralization of H5N1 Influenza Virus.
J. Virol., 92, 2018
6A0Z
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CRYSTAL STRUCTURE OF BROADLY NEUTRALIZING ANTIBODY 13D4 BOUND TO H5N1 INFLUENZA HEMAGGLUTININ, HA HEAD REGION
Descriptor:Hemagglutinin,Envelope glycoprotein, Antibody 13D4, Fab Heavy Chain, ...
Authors:Li, S., Li, T.
Deposit date:2018-06-06
Release date:2018-06-20
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (2.329 Å)
Cite:Structural Basis for the Broad, Antibody-Mediated Neutralization of H5N1 Influenza Virus.
J. Virol., 92, 2018
4GG5
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CRYSTAL STRUCTURE OF CMET IN COMPLEX WITH NOVEL INHIBITOR
Descriptor:Hepatocyte growth factor receptor, 3-(4-methylpiperazin-1-yl)-N-(3-nitrobenzyl)-7-(trifluoromethyl)quinolin-5-amine
Authors:Liu, Q.F., Chen, T.T., Xu, Y.C.
Deposit date:2012-08-05
Release date:2012-10-03
Last modified:2012-10-17
Method:X-RAY DIFFRACTION (2.423 Å)
Cite:Multisubstituted quinoxalines and pyrido[2,3-d]pyrimidines: Synthesis and SAR study as tyrosine kinase c-Met inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
4GG7
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CRYSTAL STRUCTURE OF CMET IN COMPLEX WITH NOVEL INHIBITOR
Descriptor:Hepatocyte growth factor receptor, N-(3-nitrobenzyl)-6-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-2-(trifluoromethyl)pyrido[2,3-d]pyrimidin-4-amine
Authors:Liu, Q.F., Chen, T.T., Xu, Y.C.
Deposit date:2012-08-06
Release date:2012-10-03
Last modified:2012-10-17
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Multisubstituted quinoxalines and pyrido[2,3-d]pyrimidines: Synthesis and SAR study as tyrosine kinase c-Met inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
3L0I
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COMPLEX STRUCTURE OF SIDM/DRRA WITH THE WILD TYPE RAB1
Descriptor:DrrA, Ras-related protein Rab-1A, SULFATE ION, ...
Authors:Zhu, Y., Shao, F.
Deposit date:2009-12-10
Release date:2009-12-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural mechanism of host Rab1 activation by the bifunctional Legionella type IV effector SidM/DrrA
Proc.Natl.Acad.Sci.USA, 107, 2010
3L0M
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CRYSTAL STRUCTURE OF RAB1-ACTIVATION DOMAIN AND P4M DOMAIN OF SIDM/DRRA FROM LEGIONELLA
Descriptor:DrrA, SULFATE ION
Authors:Zhu, Y., Shao, F.
Deposit date:2009-12-10
Release date:2009-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structural mechanism of host Rab1 activation by the bifunctional Legionella type IV effector SidM/DrrA
Proc.Natl.Acad.Sci.USA, 107, 2010
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