Author results

2UXN
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STRUCTURAL BASIS OF HISTONE DEMETHYLATION BY LSD1 REVEALED BY SUICIDE INACTIVATION
分子名称:LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, REST COREPRESSOR 1, HISTONE H3.1, ...
著者Yang, M., Culhane, J.C., Szewczuk, L.M., Gocke, C.B., Brautigam, C.A., Tomchick, D.R., Machius, M., Cole, P.A., Yu, H.
登録日2007-03-28
公開日2007-05-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural Basis of Histone Demethylation by Lsd1 Revealed by Suicide Inactivation.
Nat.Struct.Mol.Biol., 14, 2007
2UXX
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HUMAN LSD1 HISTONE DEMETHYLASE-COREST IN COMPLEX WITH AN FAD- TRANYLCYPROMINE ADDUCT
分子名称:LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, REST COREPRESSOR 1, FAD-trans-2-Phenylcyclopropylamine Adduct, ...
著者Yang, M., Culhane, J.C., Machius, M., Cole, P.A., Yu, H.
登録日2007-03-30
公開日2007-08-21
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Structural Basis for the Inhibition of the Lsd1 Histone Demethylase by the Antidepressant Trans-2-Phenylcyclopropylamine.
Biochemistry, 46, 2007
2IW5
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STRUCTURAL BASIS FOR COREST-DEPENDENT DEMETHYLATION OF NUCLEOSOMES BY THE HUMAN LSD1 HISTONE DEMETHYLASE
分子名称:LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, REST COREPRESSOR 1, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Yang, M., Gocke, C.B., Luo, X., Borek, D., Tomchick, D.R., Machius, M., Otwinowski, Z., Yu, H.
登録日2006-06-26
公開日2006-08-09
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Structural Basis for Corest-Dependent Demethylation of Nucleosomes by the Human Lsd1 Histone Demethylase
Mol.Cell, 23, 2006
2VFX
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STRUCTURE OF THE SYMMETRIC MAD2 DIMER
分子名称:MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A, MAGNESIUM ION, CHLORIDE ION, ...
著者Yang, M., Li, B., Liu, C.-J., Tomchick, D.R., Machius, M., Rizo, J., Yu, H., Luo, X.
登録日2007-11-05
公開日2008-03-18
最終更新日2019-01-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Insights Into MAD2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric MAD2 Dimer.
Plos Biol., 6, 2008
2H2N
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CRYSTAL STRUCTURE OF HUMAN SOLUBLE CALCIUM-ACTIVATED NUCLEOTIDASE (SCAN) WITH CALCIUM ION
分子名称:Soluble calcium-activated nucleotidase 1, CALCIUM ION, ACETATE ION
著者Yang, M., Horii, K., Herr, A.B., Kirley, T.L.
登録日2006-05-19
公開日2006-07-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
J.Biol.Chem., 281, 2006
2H2U
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CRYSTAL STRUCTURE OF THE E130Y MUTANT OF HUMAN SOLUBLE CALCIUM-ACTIVATED NUCLEOTIDASE (SCAN) WITH CALCIUM ION
分子名称:Soluble calcium-activated nucleotidase 1, CALCIUM ION
著者Yang, M., Horii, K., Herr, A.B., Kirley, T.L.
登録日2006-05-19
公開日2006-07-18
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
J.Biol.Chem., 281, 2006
4HY6
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CRYSTAL STRUCTURE OF THE HUMAN HSP90-ALPHA N-DOMAIN BOUND TO THE HSP90 INHIBITOR FJ1
分子名称:Heat shock protein HSP 90-alpha, 6,6-dimethyl-3-(trifluoromethyl)-1,5,6,7-tetrahydro-4H-indazol-4-one
著者Yang, M., Li, J., He, J.H.
登録日2012-11-13
公開日2013-05-15
実験手法X-RAY DIFFRACTION (1.649 Å)
主引用文献Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1
to be published
4IKG
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CRYSTAL STRUCTURE OF CELL DEATH-INDUCING DFFA-LIKE EFFECTOR C
分子名称:Cell death activator CIDE-3, IODIDE ION
著者Yang, M., Gao, J.
登録日2012-12-26
公開日2014-06-04
実験手法X-RAY DIFFRACTION (1.9318 Å)
主引用文献Perilipin1 promotes unilocular lipid droplet formation through the activation of Fsp27 in adipocytes.
Nat Commun, 4, 2013
5I5N
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF MATRIX PROTEIN OF THOGOTO VIRUS AT ACIDIC PH.
分子名称:Matrix protein
著者Liu, Y., Liang, H., Yang, M.
登録日2016-02-15
公開日2016-08-17
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.418 Å)
主引用文献pH-dependent conformational changes of a Thogoto virus matrix protein reveal mechanisms of viral assembly and uncoating
J.Gen.Virol., 97, 2016
5I5O
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF MATRIX PROTEIN OF THOGOTO VIRUS AT NEUTRAL PH.
分子名称:Matrix protein
著者Liu, Y., Liang, H., Yang, M.
登録日2016-02-15
公開日2016-08-17
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.682 Å)
主引用文献pH-dependent conformational changes of a Thogoto virus matrix protein reveal mechanisms of viral assembly and uncoating
J.Gen.Virol., 97, 2016
4W78
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CRYSTAL STRUCTURE OF THE CHSH1-CHSH2 COMPLEX FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:Hydratase ChsH1, Hydratase ChsH2, CADMIUM ION, ...
著者Guja, K.E., Yang, M., Sampson, N., Garcia-Diaz, M.
登録日2014-08-21
公開日2014-10-08
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.541 Å)
主引用文献A Distinct MaoC-like Enoyl-CoA Hydratase Architecture Mediates Cholesterol Catabolism in Mycobacterium tuberculosis.
Acs Chem.Biol., 9, 2014
4WNB
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CRYSTAL STRUCTURE OF THE CHSH1-CHSH2 COMPLEX FROM MYCOBACTERIUM TUBERCULOSIS BOUND TO 3-OPC-COA
分子名称:Hydratase ChsH2, Hydratase ChsH1, CADMIUM ION, ...
著者Guja, K.E., Yang, M., Sampson, N., Garcia-Diaz, M.
登録日2014-10-11
公開日2014-10-29
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献A Distinct MaoC-like Enoyl-CoA Hydratase Architecture Mediates Cholesterol Catabolism in Mycobacterium tuberculosis.
Acs Chem.Biol., 9, 2014
4X28
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CRYSTAL STRUCTURE OF THE CHSE4-CHSE5 COMPLEX FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:Acyl-CoA dehydrogenase, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE
著者Guja, K.E., Yang, M., Sampson, N., Garcia-Diaz, M.
登録日2014-11-26
公開日2015-02-18
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 alpha 2 beta 2 Acyl-CoA Dehydrogenase Initiates beta-Oxidation of 3-Oxo-cholest-4-en-26-oyl CoA.
Acs Infect Dis., 1, 2015
3T9N
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CRYSTAL STRUCTURE OF A MEMBRANE PROTEIN
分子名称:Small-conductance mechanosensitive channel, DODECYL-BETA-D-MALTOSIDE
著者Yang, M., Zhang, X., Ge, J., Wang, J.
登録日2011-08-03
公開日2012-10-31
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (3.456 Å)
主引用文献Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance
Proc.Natl.Acad.Sci.USA, 109, 2012
4NQJ
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STRUCTURE OF COILED-COIL DOMAIN
分子名称:E3 ubiquitin-protein ligase TRIM69, DODECYL-BETA-D-MALTOSIDE
著者Yang, M., Li, Y.
登録日2013-11-25
公開日2014-05-21
実験手法X-RAY DIFFRACTION (2.152 Å)
主引用文献Structural insights into the TRIM family of ubiquitin E3 ligases
Cell Res., 2014
4PSW
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CRYSTAL STRUCTURE OF HISTONE ACETYLTRANSFERASE COMPLEX
分子名称:Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase type B subunit 2, Histone H4 type VIII, ...
著者Yang, M., Li, Y.
登録日2014-03-08
公開日2014-07-09
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
4PSX
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CRYSTAL STRUCTURE OF HISTONE ACETYLTRANSFERASE COMPLEX
分子名称:Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase type B subunit 2, Histone H4, ...
著者Yang, M., Li, Y.
登録日2014-03-08
公開日2014-07-09
実験手法X-RAY DIFFRACTION (2.509 Å)
主引用文献Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
5WY5
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CRYSTAL STRUCTURE OF MAGEG1 AND NSE1 COMPLEX
分子名称:Melanoma-associated antigen G1, Non-structural maintenance of chromosomes element 1 homolog, MAGNESIUM ION, ...
著者Yang, M., Gao, J.
登録日2017-01-11
公開日2017-05-03
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Mage-Ring Protein Complexes Comprise A Family Of E3 Ubiquitin Ligases.
Mol.Cell, 39, 2010
5YDZ
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STRUCTURE OF ENDO-LYSOSOMAL TRPML1 CHANNEL INSERTING INTO AMPHIPOL: STATE 1
分子名称:mammalian endo-lysosomal TRPML1 channel
著者Yang, M., Gao, N.
登録日2017-09-15
公開日2017-12-27
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
Protein Cell, 8, 2017
5YE1
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STRUCTURE OF ENDO-LYSOSOMAL TRPML1 CHANNEL INSERTING INTO AMPHIPOL: STATE 2
分子名称:Mucolipin-1
著者Yang, M., Gao, N.
登録日2017-09-15
公開日2017-12-27
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
Protein Cell, 8, 2017
5YE2
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MAMMALIAN ENDO-LYSOSOMAL TRPML1 CHANNEL INSERTING INTO AMPHIPOL
分子名称:mammalian endo-lysosomal TRPML1 channel
著者Yang, M., Gao, N.
登録日2017-09-15
公開日2017-12-27
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
Protein Cell, 8, 2017
5YE5
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STRUCTURE OF ENDO-LYSOSOMAL TRPML1 CHANNEL INSERTING INTO NANODISC
分子名称:mammalian endo-lysosomal TRPML1 channel, N-ACETYL-D-GLUCOSAMINE
著者Yang, M., Gao, N.
登録日2017-09-15
公開日2017-11-15
最終更新日2017-11-22
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
Protein Cell, 8, 2017
1UJ1
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CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO)
分子名称:3C-like proteinase
著者Yang, H., Yang, M., Liu, Y., Bartlam, M., Ding, Y., Lou, Z., Sun, L., Zhou, Z., Ye, S., Anand, K., Pang, H., Gao, G.F., Hilgenfeld, R., Rao, Z.
登録日2003-07-25
公開日2003-11-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
Proc.Natl.Acad.Sci.USA, 100, 2003
1UK2
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CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) AT PH8.0
分子名称:3C-LIKE PROTEINASE
著者Yang, H., Yang, M., Liu, Y., Bartlam, M., Ding, Y., Lou, Z., Sun, L., Zhou, Z., Ye, S., Anand, K., Pang, H., Gao, G.F., Hilgenfeld, R., Rao, Z.
登録日2003-08-14
公開日2003-11-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
Proc.Natl.Acad.Sci.USA, 100, 2003
1UK3
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CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) AT PH7.6
分子名称:3C-like proteinase
著者Yang, H., Yang, M., Liu, Y., Bartlam, M., Ding, Y., Lou, Z., Sun, L., Zhou, Z., Ye, S., Anand, K., Pang, H., Gao, G.F., Hilgenfeld, R., Rao, Z.
登録日2003-08-14
公開日2003-11-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
Proc.Natl.Acad.Sci.USA, 100, 2003