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1CYZ
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BU of 1cyz by Molmil
NMR STRUCTURE OF THE GAACTGGTTC/TRI-IMIDAZOLE POLYAMIDE COMPLEX
Descriptor: (2-{[4-({4-[(4-FORMYLAMINO-1-METHYL-1H-IMIDAZOLE-2-CARBONYL)-AMINO]-1-METHYL-1H-IMIDAZOLE-2-CARBONYL}-AMINO)-1-METHYL-1 H-IMIDAZOLE-2-CARBONYL]-AMINO}-ETHYL)-DIMETHYL-AMMONIUM, 5'-D(*GP*AP*AP*CP*TP*GP*GP*TP*TP*C)-3'
Authors:Yang, X.-L, Hubbard IV, R.B, Lee, M, Tao, Z.-F, Sugiyama, H, Wang, A.H.-J.
Deposit date:1999-08-31
Release date:1999-09-14
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Imidazole-imidazole pair as a minor groove recognition motif for T:G mismatched base pairs
Nucleic Acids Res., 27, 1999
1N3L
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BU of 1n3l by Molmil
Crystal structure of a human aminoacyl-tRNA synthetase cytokine
Descriptor: GLYCEROL, SULFATE ION, tyrosyl-tRNA synthetase
Authors:Yang, X.-L, Skene, R.J, McRee, D.E, Schimmel, P.
Deposit date:2002-10-28
Release date:2002-11-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Crystal structure of a human aminoacyl-tRNA synthetase cytokine
Proc.Natl.Acad.Sci.USA, 99, 2002
1NTG
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BU of 1ntg by Molmil
Crystal Structure of the EMAP II-like Cytokine Released from human tyrosyl-tRNA Synthetase
Descriptor: Tyrosyl-tRNA synthetase
Authors:Yang, X.-L, Skene, R.J, Mcree, D.E, Schimmel, P.
Deposit date:2003-01-29
Release date:2003-05-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal Structure of an EMAP-II-like Cytokine Released from a human tRNA Synthetase
Helv.Chim.Acta, 86, 2003
1Q11
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BU of 1q11 by Molmil
Crystal structure of an active fragment of human tyrosyl-tRNA synthetase with tyrosinol
Descriptor: 4-[(2S)-2-amino-3-hydroxypropyl]phenol, GLYCEROL, PHOSPHATE ION, ...
Authors:Yang, X.-L, Schimmel, P, Ribas de Pouplana, L.
Deposit date:2003-07-18
Release date:2004-01-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains
Proc.Natl.Acad.Sci.USA, 100, 2003
1R6U
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BU of 1r6u by Molmil
Crystal structure of an active fragment of human tryptophanyl-tRNA synthetase with cytokine activity
Descriptor: GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase
Authors:Yang, X.-L, Otero, F.J, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P.
Deposit date:2003-10-16
Release date:2004-01-06
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Functional and crystal structure analysis of active site adaptations of a potent anti-angiogenic human tRNA synthetase
Structure, 15, 2007
1R6T
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BU of 1r6t by Molmil
crystal structure of human tryptophanyl-tRNA synthetase
Descriptor: GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase
Authors:Yang, X.-L, Otero, F.J, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P.
Deposit date:2003-10-16
Release date:2004-01-06
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains
Proc.Natl.Acad.Sci.USA, 100, 2003
1RIQ
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BU of 1riq by Molmil
The crystal structure of the catalytic fragment of the alanyl-tRNA synthetase
Descriptor: Alanyl-tRNA synthetase
Authors:Swairjo, M.A, Otero, F.J, Yang, X.-L, Lovato, M.A, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P.
Deposit date:2003-11-17
Release date:2004-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Alanyl-tRNA Synthetase Crystal Structure and Design for Acceptor-Stem Recognition
Mol.Cell, 13, 2004
1BE5
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BU of 1be5 by Molmil
STRUCTURAL STUDIES OF A STABLE PARALLEL-STRANDED DNA DUPLEX INCORPORATING ISOGUANINE:CYTOSINE AND ISOCYTOSINE:GUANINE BASE PAIRS BY NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: DNA DUPLEX (TGCACGGACT)
Authors:Yang, X.-L, Sugiyama, H, Ikeda, S, Saito, I, Wang, A.H.-J.
Deposit date:1998-05-19
Release date:1998-08-12
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Structural studies of a stable parallel-stranded DNA duplex incorporating isoguanine:cytosine and isocytosine:guanine basepairs by nuclear magnetic resonance spectroscopy.
Biophys.J., 75, 1998
1B0S
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BU of 1b0s by Molmil
BINDING OF AR-1-144, A TRI-IMIDAZOLE DNA MINOR GROOVE BINDER, TO CCGG SEQUENCE ANALYZED BY NMR SPECTROSCOPY
Descriptor: (2-{[4-({4-[(4-FORMYLAMINO-1-METHYL-1H-IMIDAZOLE-2-CARBONYL)-AMINO]-1-METHYL-1H-IMIDAZOLE-2-CARBONYL}-AMINO)-1-METHYL-1 H-IMIDAZOLE-2-CARBONYL]-AMINO}-ETHYL)-DIMETHYL-AMMONIUM, DNA (5'-D(*GP*AP*AP*CP*CP*GP*GP*TP*TP*C)-3')
Authors:Yang, X.-L, Kaenzig, C, Lee, M, Wang, A.H.-J.
Deposit date:1998-11-12
Release date:1999-08-31
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Binding of AR-1-144, a tri-imidazole DNA minor groove binder, to CCGG sequence analyzed by NMR spectroscopy.
Eur.J.Biochem., 263, 1999
1FDG
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BU of 1fdg by Molmil
BINDING OF A MACROCYCLIC BISACRIDINE AND AMETANTRONE TO CGTACG INVOLVES SIMILAR UNUSUAL INTERCALATION PLATFORMS (AMETANTRONE COMPLEX)
Descriptor: 1,4-BIS-[2-(2-HYDROXY-ETHYLAMINO)-ETHYLAMINO]-ANTHRAQUINONE, COBALT (II) ION, DNA (5'-D(*CP*GP*TP*AP*CP*G)-3'), ...
Authors:Yang, X.-L, Robinson, H, Gao, Y.-G, Wang, A.H.-J.
Deposit date:2000-07-20
Release date:2000-08-07
Last modified:2022-09-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Binding of a macrocyclic bisacridine and ametantrone to CGTACG involves similar unusual intercalation platforms.
Biochemistry, 39, 2000
1FD5
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BU of 1fd5 by Molmil
BINDING OF A MACROCYCLIC BISACRIDINE AND AMETANTRONE TO CGTACG INVOLVES SIMILAR UNUSUAL INTERCALATION PLATFORMS (BISACRIDINE COMPLEX)
Descriptor: COBALT (II) ION, DNA (5'-D(*CP*GP*TP*AP*CP*G)-3'), MACROCYCLIC-BIS-9-AMINO-ACRIDINE, ...
Authors:Yang, X.-L, Robinson, H, Gao, Y.-G, Wang, A.H.-J.
Deposit date:2000-07-19
Release date:2000-08-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Binding of a macrocyclic bisacridine and ametantrone to CGTACG involves similar unusual intercalation platforms.
Biochemistry, 39, 2000
3VBB
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BU of 3vbb by Molmil
Crystal Structure of Seryl-tRNA Synthetase from Human at 2.9 angstroms
Descriptor: MAGNESIUM ION, PHOSPHATE ION, Seryl-tRNA synthetase, ...
Authors:Xu, X.L, Yang, X.-L.
Deposit date:2012-01-02
Release date:2012-02-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.891 Å)
Cite:Unique domain appended to vertebrate tRNA synthetase is essential for vascular development.
Nat Commun, 3, 2012
1I3W
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BU of 1i3w by Molmil
ACTINOMYCIN D BINDING TO CGATCGATCG
Descriptor: 5'-D(*C*GP*AP*TP*CP*GP*AP*(BRU)P*CP*GP)-3', ACTINOMYCIN D
Authors:Robinson, H, Gao, Y.-G, Yang, X.-L, Sanishvili, R, Joachimiak, A, Wang, A.H.-J.
Deposit date:2001-02-17
Release date:2001-05-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystallographic Analysis of a Novel Complex of Actinomycin D Bound to the DNA Decamer Cgatcgatcg.
Biochemistry, 40, 2001
5KNN
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BU of 5knn by Molmil
Evolutionary gain of alanine mischarging to non-cognate tRNAs with a G4:U69 base pair
Descriptor: '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, Alanine--tRNA ligase, cytoplasmic
Authors:Sun, L, He, W, Yang, X.-L.
Deposit date:2016-06-28
Release date:2016-09-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Evolutionary Gain of Alanine Mischarging to Noncognate tRNAs with a G4:U69 Base Pair.
J.Am.Chem.Soc., 138, 2016
5UJJ
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BU of 5ujj by Molmil
Crystal structure of human H130R tryptophanyl-tRNA synthetase in complex with TrpAMP
Descriptor: MAGNESIUM ION, TRYPTOPHANYL-5'AMP, Tryptophan--tRNA ligase, ...
Authors:Xu, X, Yang, X.-L.
Deposit date:2017-01-18
Release date:2018-01-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An alternative conformation of human TrpRS suggests a role of zinc in activating non-enzymatic function.
RNA Biol, 15, 2018
5UJI
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BU of 5uji by Molmil
Crystal structure of human T2-Tryptophanyl-tRNA synthetase with H130R mutation
Descriptor: Tryptophan--tRNA ligase, cytoplasmic
Authors:Xu, X, Yang, X.-L.
Deposit date:2017-01-18
Release date:2018-01-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:An alternative conformation of human TrpRS suggests a role of zinc in activating non-enzymatic function.
RNA Biol, 15, 2018
4G84
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BU of 4g84 by Molmil
Crystal structure of human HisRS
Descriptor: CHLORIDE ION, Histidine--tRNA ligase, cytoplasmic, ...
Authors:Wei, Z, Wu, J, Zhou, J.J, Yang, X.-L, Zhang, M, Schimmel, P.
Deposit date:2012-07-21
Release date:2012-09-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing.
Structure, 20, 2012
4G85
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BU of 4g85 by Molmil
Crystal structure of human HisRS
Descriptor: Histidine-tRNA ligase, cytoplasmic
Authors:Wei, Z, Wu, J, Zhou, J.J, Yang, X.-L, Zhang, M, Schimmel, P.
Deposit date:2012-07-21
Release date:2012-09-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing.
Structure, 20, 2012
4L87
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BU of 4l87 by Molmil
Crystal structure of the human seryl-tRNA synthetase in complex with Ser-SA at 2.9 Angstrom resolution
Descriptor: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Xu, X, Yang, X.-L.
Deposit date:2013-06-16
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.897 Å)
Cite:Crystal Structure of Human Seryl-tRNA Synthetase and Ser-SA Complex Reveals a Molecular Lever Specific to Higher Eukaryotes.
Structure, 21, 2013
3HY0
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BU of 3hy0 by Molmil
Crystal Structure of catalytic fragment of E. coli AlaRS G237A in complex with GlySA
Descriptor: 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-(glycylsulfamoyl)adenosine, ...
Authors:Guo, M, Yang, X.-L, Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXX
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BU of 3hxx by Molmil
Crystal Structure of catalytic fragment of E. coli AlaRS in complex with AMPPCP
Descriptor: Alanyl-tRNA synthetase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
Authors:Guo, M, Yang, X.-L, Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXW
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BU of 3hxw by Molmil
Crystal Structure of catalytic fragment of E. coli AlaRS in complex with SerSA
Descriptor: 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, ...
Authors:Guo, M, Yang, X.-L, Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXY
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BU of 3hxy by Molmil
Crystal Structure of catalytic fragment of E. coli AlaRS in complex with AMPPCP, Ala-AMP and PCP
Descriptor: 2-HYDROXYETHYL DISULFIDE, 5'-O-[(R)-{[(2S)-2-aminopropanoyl]oxy}(hydroxy)phosphoryl]adenosine, Alanyl-tRNA synthetase, ...
Authors:Guo, M, Yang, X.-L, Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXU
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BU of 3hxu by Molmil
Crystal Structure of catalytic fragment of E. coli AlaRS in complex with AlaSA
Descriptor: '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Guo, M, Yang, X.-L, Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXV
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BU of 3hxv by Molmil
Crystal Structure of catalytic fragment of E. coli AlaRS in complex with GlySA
Descriptor: 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-(glycylsulfamoyl)adenosine, ...
Authors:Guo, M, Yang, X.-L, Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009

 

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