Author results

1CYZ
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NMR STRUCTURE OF THE GAACTGGTTC/TRI-IMIDAZOLE POLYAMIDE COMPLEX
Descriptor:5'-D(*GP*AP*AP*CP*TP*GP*GP*TP*TP*C)-3', (2-{[4-({4-[(4-FORMYLAMINO-1-METHYL-1H-IMIDAZOLE-2-CARBONYL)-AMINO]-1-METHYL-1H-IMIDAZOLE-2-CARBONYL}-AMINO)-1-METHYL-1H-IMIDAZOLE-2-CARBONYL]-AMINO}-ETHYL)-DIMETHYL-AMMONIUM
Authors:Yang, X.-L., Hubbard IV, R.B., Lee, M., Tao, Z.-F., Sugiyama, H., Wang, A.H.-J.
Deposit date:1999-08-31
Release date:1999-09-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Imidazole-imidazole pair as a minor groove recognition motif for T:G mismatched base pairs
Nucleic Acids Res., 27, 1999
1N3L
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CRYSTAL STRUCTURE OF A HUMAN AMINOACYL-TRNA SYNTHETASE CYTOKINE
Descriptor:tyrosyl-tRNA synthetase, SULFATE ION, GLYCEROL
Authors:Yang, X.-L., Skene, R.J., McRee, D.E., Schimmel, P.
Deposit date:2002-10-28
Release date:2002-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Crystal structure of a human aminoacyl-tRNA synthetase cytokine
Proc.Natl.Acad.Sci.USA, 99, 2002
1NTG
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CRYSTAL STRUCTURE OF THE EMAP II-LIKE CYTOKINE RELEASED FROM HUMAN TYROSYL-TRNA SYNTHETASE
Descriptor:Tyrosyl-tRNA synthetase
Authors:Yang, X.-L., Skene, R.J., Mcree, D.E., Schimmel, P.
Deposit date:2003-01-29
Release date:2003-05-13
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal Structure of an EMAP-II-like Cytokine Released from a human tRNA Synthetase
Helv.Chim.Acta, 86, 2003
1Q11
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CRYSTAL STRUCTURE OF AN ACTIVE FRAGMENT OF HUMAN TYROSYL-TRNA SYNTHETASE WITH TYROSINOL
Descriptor:Tyrosyl-tRNA synthetase, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Yang, X.-L., Schimmel, P., Ribas de Pouplana, L.
Deposit date:2003-07-18
Release date:2004-01-06
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains
Proc.Natl.Acad.Sci.USA, 100, 2003
1R6T
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CRYSTAL STRUCTURE OF HUMAN TRYPTOPHANYL-TRNA SYNTHETASE
Descriptor:Tryptophanyl-tRNA synthetase, TRYPTOPHANYL-5'AMP, GLYCEROL
Authors:Yang, X.-L., Otero, F.J., Skene, R.J., McRee, D.E., Ribas de Pouplana, L., Schimmel, P.
Deposit date:2003-10-16
Release date:2004-01-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains
Proc.Natl.Acad.Sci.USA, 100, 2003
1R6U
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CRYSTAL STRUCTURE OF AN ACTIVE FRAGMENT OF HUMAN TRYPTOPHANYL-TRNA SYNTHETASE WITH CYTOKINE ACTIVITY
Descriptor:Tryptophanyl-tRNA synthetase, TRYPTOPHANYL-5'AMP, GLYCEROL
Authors:Yang, X.-L., Otero, F.J., Skene, R.J., McRee, D.E., Ribas de Pouplana, L., Schimmel, P.
Deposit date:2003-10-16
Release date:2004-01-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Functional and crystal structure analysis of active site adaptations of a potent anti-angiogenic human tRNA synthetase
Structure, 15, 2007
1RIQ
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THE CRYSTAL STRUCTURE OF THE CATALYTIC FRAGMENT OF THE ALANYL-TRNA SYNTHETASE
Descriptor:Alanyl-tRNA synthetase
Authors:Swairjo, M.A., Otero, F.J., Yang, X.-L., Lovato, M.A., Skene, R.J., McRee, D.E., Ribas de Pouplana, L., Schimmel, P.
Deposit date:2003-11-17
Release date:2004-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Alanyl-tRNA Synthetase Crystal Structure and Design for Acceptor-Stem Recognition
Mol.Cell, 13, 2004
1B0S
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BINDING OF AR-1-144, A TRI-IMIDAZOLE DNA MINOR GROOVE BINDER, TO CCGG SEQUENCE ANALYZED BY NMR SPECTROSCOPY
Descriptor:DNA (5'-D(*GP*AP*AP*CP*CP*GP*GP*TP*TP*C)-3'), (2-{[4-({4-[(4-FORMYLAMINO-1-METHYL-1H-IMIDAZOLE-2-CARBONYL)-AMINO]-1-METHYL-1H-IMIDAZOLE-2-CARBONYL}-AMINO)-1-METHYL-1H-IMIDAZOLE-2-CARBONYL]-AMINO}-ETHYL)-DIMETHYL-AMMONIUM
Authors:Yang, X.-L., Kaenzig, C., Lee, M., Wang, A.H.-J.
Deposit date:1998-11-12
Release date:1999-08-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Binding of AR-1-144, a tri-imidazole DNA minor groove binder, to CCGG sequence analyzed by NMR spectroscopy.
Eur.J.Biochem., 263, 1999
1BE5
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STRUCTURAL STUDIES OF A STABLE PARALLEL-STRANDED DNA DUPLEX INCORPORATING ISOGUANINE:CYTOSINE AND ISOCYTOSINE:GUANINE BASE PAIRS BY NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:DNA DUPLEX (TGCACGGACT)
Authors:Yang, X.-L., Sugiyama, H., Ikeda, S., Saito, I., Wang, A.H.-J.
Deposit date:1998-05-19
Release date:1998-08-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural studies of a stable parallel-stranded DNA duplex incorporating isoguanine:cytosine and isocytosine:guanine basepairs by nuclear magnetic resonance spectroscopy.
Biophys.J., 75, 1998
1FD5
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BINDING OF A MACROCYCLIC BISACRIDINE AND AMETANTRONE TO CGTACG INVOLVES SIMILAR UNUSUAL INTERCALATION PLATFORMS (BISACRIDINE COMPLEX)
Descriptor:DNA (5'-D(*CP*GP*TP*AP*CP*G)-3'), COBALT (II) ION, MACROCYCLIC-BIS-9-AMINO-ACRIDINE, ...
Authors:Yang, X.-L., Robinson, H., Gao, Y.-G., Wang, A.H.-J.
Deposit date:2000-07-19
Release date:2000-08-07
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Binding of a macrocyclic bisacridine and ametantrone to CGTACG involves similar unusual intercalation platforms.
Biochemistry, 39, 2000
1FDG
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BINDING OF A MACROCYCLIC BISACRIDINE AND AMETANTRONE TO CGTACG INVOLVES SIMILAR UNUSUAL INTERCALATION PLATFORMS (AMETANTRONE COMPLEX)
Descriptor:DNA (5'-D(*CP*GP*TP*AP*CP*G)-3'), COBALT (II) ION, 1,4-BIS-[2-(2-HYDROXY-ETHYLAMINO)-ETHYLAMINO]-ANTHRAQUINONE, ...
Authors:Yang, X.-L., Robinson, H., Gao, Y.-G., Wang, A.H.-J.
Deposit date:2000-07-20
Release date:2000-08-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Binding of a macrocyclic bisacridine and ametantrone to CGTACG involves similar unusual intercalation platforms.
Biochemistry, 39, 2000
1I3W
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ACTINOMYCIN D BINDING TO CGATCGATCG
Descriptor:5'-D(*C*GP*AP*TP*CP*GP*AP*(BRU)P*CP*GP)-3', ACTINOMYCIN D
Authors:Robinson, H., Gao, Y.-G., Yang, X.-L., Sanishvili, R., Joachimiak, A., Wang, A.H.-J.
Deposit date:2001-02-17
Release date:2001-05-21
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystallographic Analysis of a Novel Complex of Actinomycin D Bound to the DNA Decamer Cgatcgatcg.
Biochemistry, 40, 2001
3HXU
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS IN COMPLEX WITH ALASA
Descriptor:Alanyl-tRNA synthetase, '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, 2-HYDROXYETHYL DISULFIDE, ...
Authors:Guo, M., Yang, X.-L., Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXV
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS IN COMPLEX WITH GLYSA
Descriptor:Alanyl-tRNA synthetase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 2-HYDROXYETHYL DISULFIDE, ...
Authors:Guo, M., Yang, X.-L., Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXW
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS IN COMPLEX WITH SERSA
Descriptor:Alanyl-tRNA synthetase, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Guo, M., Yang, X.-L., Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXX
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS IN COMPLEX WITH AMPPCP
Descriptor:Alanyl-tRNA synthetase, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, MAGNESIUM ION
Authors:Guo, M., Yang, X.-L., Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXY
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS IN COMPLEX WITH AMPPCP, ALA-AMP AND PCP
Descriptor:Alanyl-tRNA synthetase, 5'-O-[(R)-{[(2S)-2-aminopropanoyl]oxy}(hydroxy)phosphoryl]adenosine, METHYLENEDIPHOSPHONIC ACID, ...
Authors:Guo, M., Yang, X.-L., Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXZ
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS G237A IN COMPLEX WITH ALASA
Descriptor:Alanyl-tRNA synthetase, '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Guo, M., Yang, X.-L., Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HY0
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS G237A IN COMPLEX WITH GLYSA
Descriptor:Alanyl-tRNA synthetase, 5'-O-(glycylsulfamoyl)adenosine, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Guo, M., Yang, X.-L., Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HY1
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS G237A IN COMPLEX WITH SERSA
Descriptor:Alanyl-tRNA synthetase, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, 2-HYDROXYETHYL DISULFIDE, ...
Authors:Guo, M., Yang, X.-L., Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3VBB
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CRYSTAL STRUCTURE OF SERYL-TRNA SYNTHETASE FROM HUMAN AT 2.9 ANGSTROMS
Descriptor:Seryl-tRNA synthetase, cytoplasmic, MAGNESIUM ION, ...
Authors:Xu, X.L., Yang, X.-L.
Deposit date:2012-01-02
Release date:2012-02-29
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (2.891 Å)
Cite:Unique domain appended to vertebrate tRNA synthetase is essential for vascular development.
Nat Commun, 3, 2012
4G84
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CRYSTAL STRUCTURE OF HUMAN HISRS
Descriptor:Histidine--tRNA ligase, cytoplasmic, IMIDAZOLE, ...
Authors:Wei, Z., Wu, J., Zhou, J.J., Yang, X.-L., Zhang, M., Schimmel, P.
Deposit date:2012-07-21
Release date:2012-09-26
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing.
Structure, 20, 2012
4G85
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CRYSTAL STRUCTURE OF HUMAN HISRS
Descriptor:Histidine-tRNA ligase, cytoplasmic
Authors:Wei, Z., Wu, J., Zhou, J.J., Yang, X.-L., Zhang, M., Schimmel, P.
Deposit date:2012-07-21
Release date:2012-09-26
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing.
Structure, 20, 2012
4L87
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CRYSTAL STRUCTURE OF THE HUMAN SERYL-TRNA SYNTHETASE IN COMPLEX WITH SER-SA AT 2.9 ANGSTROM RESOLUTION
Descriptor:Serine--tRNA ligase, cytoplasmic, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, ...
Authors:Xu, X., Yang, X.-L.
Deposit date:2013-06-16
Release date:2013-10-02
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.897 Å)
Cite:Crystal Structure of Human Seryl-tRNA Synthetase and Ser-SA Complex Reveals a Molecular Lever Specific to Higher Eukaryotes.
Structure, 21, 2013
5KNN
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EVOLUTIONARY GAIN OF ALANINE MISCHARGING TO NON-COGNATE TRNAS WITH A G4:U69 BASE PAIR
Descriptor:Alanine--tRNA ligase, cytoplasmic, '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE
Authors:Sun, L., He, W., Yang, X.-L.
Deposit date:2016-06-28
Release date:2016-09-28
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Evolutionary Gain of Alanine Mischarging to Noncognate tRNAs with a G4:U69 Base Pair.
J.Am.Chem.Soc., 138, 2016
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