Author results

1T6W
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RATIONAL DESIGN OF A CALCIUM-BINDING ADHESION PROTEIN NMR, 20 STRUCTURES
Descriptor:hypothetical protein XP_346638, CALCIUM ION
Authors:Yang, W., Wilkins, A.L., Ye, Y., Liu, Z.-R., Urbauer, J.L., Kearney, A., van der Merwe, P.A., Yang, J.J.
Deposit date:2004-05-07
Release date:2005-02-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Design of a calcium-binding protein with desired structure in a cell adhesion molecule.
J.Am.Chem.Soc., 127, 2005
5FBH
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN CALCIUM SENSING RECEPTOR WITH BOUND GD3+
Descriptor:Extracellular calcium-sensing receptor, GADOLINIUM ION, MAGNESIUM ION, ...
Authors:Zhang, T., Zhang, C., Miller, C.L., Zou, J., Moremen, K.W., Brown, E.M., Yang, J.J., Hu, J.
Deposit date:2015-12-14
Release date:2016-06-22
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.
Sci Adv, 2, 2016
5FBK
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN CALCIUM SENSING RECEPTOR
Descriptor:Extracellular calcium-sensing receptor, CYCLOMETHYLTRYPTOPHAN, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zhang, T., Zhang, C., Miller, C.L., Zou, J., Moremen, K.W., Brown, E.M., Yang, J.J., Hu, J.
Deposit date:2015-12-14
Release date:2016-06-22
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.
Sci Adv, 2, 2016
3Q96
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B-RAF KINASE DOMAIN IN COMPLEX WITH A TETRAHYDRONAPHTHALENE INHIBITOR
Descriptor:Serine/threonine-protein kinase B-raf, (2S)-N-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-7-[(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-4-yl)oxy]-1,2,3,4-tetrahydronaphthalene-2-carboxamide
Authors:Sintchak, M.D., Aertgeerts, K., Yano, J.
Deposit date:2011-01-07
Release date:2011-03-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Design and optimization of potent and orally bioavailable tetrahydronaphthalene raf inhibitors.
J.Med.Chem., 54, 2011
4L12
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CRYSTAL STRUCTURE OF EGFP-BASED CALCIUM SENSOR CATCHER COMPLEXED WITH GD
Descriptor:EGFP-based Calcium Sensor CatchER, GADOLINIUM ATOM
Authors:Zhang, Y., Weber, I.T.
Deposit date:2013-06-01
Release date:2013-12-11
Last modified:2014-01-08
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural basis for a hand-like site in the calcium sensor CatchER with fast kinetics.
Acta Crystallogr.,Sect.D, 69, 2013
4L13
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CRYSTAL STRUCTURE OF LIGAND FREE EGFP-BASED CALCIUM SENSOR CATCHER
Descriptor:EGFP-based Calcium Sensor CatchER, ACETIC ACID
Authors:Zhang, Y., Weber, I.T.
Deposit date:2013-06-01
Release date:2013-12-11
Last modified:2014-01-08
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural basis for a hand-like site in the calcium sensor CatchER with fast kinetics.
Acta Crystallogr.,Sect.D, 69, 2013
4L1I
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CRYSTAL STRUCTURE OF EGFP-BASED CALCIUM SENSOR CATCHER COMPLEXED WITH CA
Descriptor:EGFP-based Calcium Sensor CatchER, CALCIUM ION
Authors:Zhang, Y., Weber, I.T.
Deposit date:2013-06-03
Release date:2013-12-11
Last modified:2014-01-08
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural basis for a hand-like site in the calcium sensor CatchER with fast kinetics.
Acta Crystallogr.,Sect.D, 69, 2013
5OPK
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CRYSTAL STRUCTURE OF D52N/R367Q CN-II MUTANT BOUND TO DATP AND FREE PHOSPHATE
Descriptor:Cytosolic purine 5'-nucleotidase, GLYCEROL, PHOSPHATE ION, ...
Authors:Hnizda, A., Pachl, P., Rezacova, P.
Deposit date:2017-08-10
Release date:2018-06-13
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPL
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CRYSTAL STRUCTURE OF K25E CN-II MUTANT
Descriptor:Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION
Authors:Kugler, M., Hnizda, A., Pachl, P., Rezacova, P.
Deposit date:2017-08-10
Release date:2018-06-13
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPM
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CRYSTAL STRUCTURE OF D52N/R238W CN-II MUTANT BOUND TO DATP AND FREE PHOSPHATE
Descriptor:Cytosolic purine 5'-nucleotidase, PHOSPHATE ION, MAGNESIUM ION, ...
Authors:Hnizda, A., Pachl, P., Rezacova, P.
Deposit date:2017-08-10
Release date:2018-06-13
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPN
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CRYSTAL STRUCTURE OF R39Q CN-II MUTANT
Descriptor:Cytosolic purine 5'-nucleotidase, GLYCEROL
Authors:Hnizda, A., Pachl, P., Rezacova, P.
Deposit date:2017-08-10
Release date:2018-06-13
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPO
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CRYSTAL STRUCTURE OF R238G CN-II MUTANT
Descriptor:Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION
Authors:Hnizda, A., Pachl, P., Rezacova, P.
Deposit date:2017-08-10
Release date:2018-06-13
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPP
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CRYSTAL STRUCTURE OF S408R CN-II MUTANT
Descriptor:Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION, ...
Authors:Hnizda, A., Pachl, P., Rezacova, P.
Deposit date:2017-08-10
Release date:2018-06-13
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018