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8EJX
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BU of 8ejx by Molmil
Crystal structure of human cyclophilin D (CypD) with in complex with the covalently bound Ebselen inhibitor
Descriptor: N-phenyl-2-selanylbenzamide, Peptidyl-prolyl cis-trans isomerase F, mitochondrial
Authors:Lovell, S, Battaile, K.P, Yan, S.
Deposit date:2022-09-19
Release date:2023-10-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:New cyclophilin D inhibitor rescues mitochondrial and cognitive function in Alzheimer's disease.
Brain, 2023
1SO8
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BU of 1so8 by Molmil
Abeta-bound human ABAD structure [also known as 3-hydroxyacyl-CoA dehydrogenase type II (Type II HADH), Endoplasmic reticulum-associated amyloid beta-peptide binding protein (ERAB)]
Descriptor: 3-hydroxyacyl-CoA dehydrogenase type II, CHLORIDE ION, SODIUM ION
Authors:Lustbader, J.W, Cirilli, M, Wu, H.
Deposit date:2004-03-13
Release date:2004-05-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
Science, 304, 2004
4O8I
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BU of 4o8i by Molmil
1.45A resolution structure of PEG 400 Bound Cyclophilin D
Descriptor: PENTAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase F, mitochondrial
Authors:Lovell, S, Valasani, K.R, Battaile, K.P, Wang, C, Yan, S.S.
Deposit date:2013-12-27
Release date:2014-06-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:High-resolution crystal structures of two crystal forms of human cyclophilin D in complex with PEG 400 molecules.
Acta Crystallogr F Struct Biol Commun, 70, 2014
4O8H
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BU of 4o8h by Molmil
0.85A resolution structure of PEG 400 Bound Cyclophilin D
Descriptor: DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase F, ...
Authors:Lovell, S, Valasani, K.R, Battaile, K.P, Wang, C, Yan, S.S.
Deposit date:2013-12-27
Release date:2014-06-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (0.85 Å)
Cite:High-resolution crystal structures of two crystal forms of human cyclophilin D in complex with PEG 400 molecules.
Acta Crystallogr F Struct Biol Commun, 70, 2014

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PDB entries from 2024-04-17

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