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3JB9
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BU of 3jb9 by Molmil
Cryo-EM structure of the yeast spliceosome at 3.6 angstrom resolution
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Yan, C, Hang, J, Wan, R, Huang, M, Wong, C, Shi, Y.
Deposit date:2015-08-09
Release date:2015-09-23
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of a yeast spliceosome at 3.6-angstrom resolution
Science, 349, 2015
5GM6
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BU of 5gm6 by Molmil
Cryo-EM structure of the activated spliceosome (Bact complex) at 3.5 angstrom resolution
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cold sensitive U2 snRNA suppressor 1, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Yan, C, Wan, R, Bai, R, Huang, G, Shi, Y.
Deposit date:2016-07-12
Release date:2016-09-21
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of a yeast activated spliceosome at 3.5 angstrom resolution
Science, 353, 2016
5WSG
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BU of 5wsg by Molmil
Cryo-EM structure of the Catalytic Step II spliceosome (C* complex) at 4.0 angstrom resolution
Descriptor: 3'-exon-intron, 3'-intron-lariat, 5'-exon, ...
Authors:Yan, C, Wan, R, Bai, R, Huang, G, Shi, Y.
Deposit date:2016-12-07
Release date:2017-01-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of a yeast step II catalytically activated spliceosome
Science, 355, 2017
1B5B
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BU of 1b5b by Molmil
RAT FERROCYTOCHROME B5 B CONFORMATION, NMR, 1 STRUCTURE
Descriptor: FERROCYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
Authors:Dangi, B, Sarma, S, Yan, C, Banville, D, Guiles, R.D.
Deposit date:1998-04-06
Release date:1998-06-17
Last modified:2018-08-08
Method:SOLUTION NMR
Cite:The origin of differences in the physical properties of the equilibrium forms of cytochrome b5 revealed through high-resolution NMR structures and backbone dynamic analyses.
Biochemistry, 37, 1998
8JTS
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BU of 8jts by Molmil
hOCT1 in complex with metformin in outward open conformation
Descriptor: Metformin, Solute carrier family 22 member 1
Authors:Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X.
Deposit date:2023-06-22
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (4.14 Å)
Cite:Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
8JTT
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BU of 8jtt by Molmil
hOCT1 in complex with metformin in outward occluded conformation
Descriptor: Metformin, Solute carrier family 22 member 1
Authors:Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X.
Deposit date:2023-06-22
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
8JTV
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BU of 8jtv by Molmil
hOCT1 in complex with metformin in inward occluded conformation
Descriptor: Metformin, Solute carrier family 22 member 1
Authors:Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X.
Deposit date:2023-06-22
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.77 Å)
Cite:Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
8JTW
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BU of 8jtw by Molmil
hOCT1 in complex with nb5660 in inward facing partially open 1 conformation
Descriptor: Solute carrier family 22 member 1, nanobody 56
Authors:Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X.
Deposit date:2023-06-22
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
8JTX
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BU of 8jtx by Molmil
hOCT1 in complex with nb5660 in inward facing fully open conformation
Descriptor: Solute carrier family 22 member 1, nanobody 56
Authors:Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X.
Deposit date:2023-06-22
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
8JTY
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BU of 8jty by Molmil
hOCT1 in complex with nb5660 in inward facing partially open 2 conformation
Descriptor: Solute carrier family 22 member 1, nanobody 56
Authors:Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X.
Deposit date:2023-06-22
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
8JTZ
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BU of 8jtz by Molmil
hOCT1 in complex with spironolactone in outward facing partially occluded conformation
Descriptor: SPIRONOLACTONE, Solute carrier family 22 member 1
Authors:Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X.
Deposit date:2023-06-22
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
8JU0
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BU of 8ju0 by Molmil
hOCT1 in complex with spironolactone in inward facing occluded conformation
Descriptor: SPIRONOLACTONE, Solute carrier family 22 member 1
Authors:Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X.
Deposit date:2023-06-23
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
1B5A
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BU of 1b5a by Molmil
RAT FERROCYTOCHROME B5 A CONFORMATION, NMR, 1 STRUCTURE
Descriptor: FERROCYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
Authors:Dangi, B, Sarma, S, Yan, C, Banville, D, Guiles, R.D.
Deposit date:1998-04-06
Release date:1998-06-17
Last modified:2018-08-08
Method:SOLUTION NMR
Cite:The origin of differences in the physical properties of the equilibrium forms of cytochrome b5 revealed through high-resolution NMR structures and backbone dynamic analyses.
Biochemistry, 37, 1998
4RNG
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BU of 4rng by Molmil
Crystal structure of a bacterial homologue of SWEET transporters
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, MtN3/saliva family, SULFATE ION
Authors:Hu, Q, Wang, J, Yan, C, Yan, N.
Deposit date:2014-10-24
Release date:2014-11-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of a bacterial homologue of SWEET transporters.
Cell Res., 24, 2014
4RHW
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BU of 4rhw by Molmil
Crystal structure of Apaf-1 CARD and caspase-9 CARD complex
Descriptor: Apoptotic protease-activating factor 1, CHLORIDE ION, Caspase-9, ...
Authors:Hu, Q, Wu, D, Yan, C, Shi, Y.
Deposit date:2014-10-03
Release date:2014-10-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome.
Proc. Natl. Acad. Sci. U.S.A., 111, 2014
3J8H
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BU of 3j8h by Molmil
Structure of the rabbit ryanodine receptor RyR1 in complex with FKBP12 at 3.8 Angstrom resolution
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ZINC ION
Authors:Yan, Z, Bai, X, Yan, C, Wu, J, Scheres, S.H.W, Shi, Y, Yan, N.
Deposit date:2014-10-26
Release date:2014-12-10
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution.
Nature, 517, 2015
1S9I
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BU of 1s9i by Molmil
X-ray structure of the human mitogen-activated protein kinase kinase 2 (MEK2)in a complex with ligand and MgATP
Descriptor: 5-{3,4-DIFLUORO-2-[(2-FLUORO-4-IODOPHENYL)AMINO]PHENYL}-N-(2-MORPHOLIN-4-YLETHYL)-1,3,4-OXADIAZOL-2-AMINE, ADENOSINE-5'-TRIPHOSPHATE, Dual specificity mitogen-activated protein kinase kinase 2, ...
Authors:Ohren, J.F, Chen, H, Pavlovsky, A, Whitehead, C, Yan, C, McConnell, P, Delaney, A, Dudley, D.T, Sebolt-Leopold, J, Hasemann, C.A.
Deposit date:2004-02-04
Release date:2004-11-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition.
Nat.Struct.Mol.Biol., 11, 2004
1S9J
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BU of 1s9j by Molmil
X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a complex with ligand and MgATP
Descriptor: 5-BROMO-N-(2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-[(2-FLUORO-4-IODOPHENYL)AMINO]BENZAMIDE, ADENOSINE-5'-TRIPHOSPHATE, Dual specificity mitogen-activated protein kinase kinase 1, ...
Authors:Ohren, J.F, Chen, H, Pavlovsky, A, Whitehead, C, Yan, C, McConnell, P, Delaney, A, Dudley, D.T, Sebolt-Leopold, J, Hasemann, C.A.
Deposit date:2004-02-04
Release date:2004-11-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition.
Nat.Struct.Mol.Biol., 11, 2004
4DNW
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BU of 4dnw by Molmil
Crystal structure of UVB-resistance protein UVR8
Descriptor: AT5g63860/MGI19_6
Authors:Wu, D, Hu, Q, Yan, Z, Chen, W, Yan, C, Wang, J, Shi, Y.
Deposit date:2012-02-09
Release date:2012-03-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.773 Å)
Cite:Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
4DNV
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BU of 4dnv by Molmil
Crystal structure of the W285F mutant of UVB-resistance protein UVR8
Descriptor: AT5g63860/MGI19_6
Authors:Wu, D, Hu, Q, Yan, Z, Chen, W, Yan, C, Zhang, J, Wang, J, Shi, Y.
Deposit date:2012-02-09
Release date:2012-03-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
4DNU
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BU of 4dnu by Molmil
Crystal structure of the W285A mutant of UVB-resistance protein UVR8
Descriptor: AT5g63860/MGI19_6
Authors:Wu, D, Hu, Q, Yan, Z, Chen, W, Yan, C, Zhang, J, Wang, J, Shi, Y.
Deposit date:2012-02-09
Release date:2012-03-07
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.764 Å)
Cite:Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
3RT0
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BU of 3rt0 by Molmil
Crystal structure of PYL10-HAB1 complex in the absence of abscisic acid (ABA)
Descriptor: Abscisic acid receptor PYL10, MAGNESIUM ION, Protein phosphatase 2C 16
Authors:Hao, Q, Yin, P, Li, W, Wang, L, Yan, C, Wang, J, Yan, N.
Deposit date:2011-05-02
Release date:2011-06-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.113 Å)
Cite:The Molecular Basis of ABA-Independent Inhibition of PP2Cs by a Subclass of PYL Proteins
Mol.Cell, 42, 2011
3RT2
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BU of 3rt2 by Molmil
Crystal structure of apo-PYL10
Descriptor: Abscisic acid receptor PYL10
Authors:Hao, Q, Yin, P, Li, W, Wang, L, Yan, C, Wang, J, Yan, N.
Deposit date:2011-05-02
Release date:2011-06-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Molecular Basis of ABA-Independent Inhibition of PP2Cs by a Subclass of PYL Proteins
Mol.Cell, 42, 2011
4R12
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BU of 4r12 by Molmil
Crystal structure of the gamma-secretase component Nicastrin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Xie, T, Yan, C, Zhou, R, Zhao, Y, Sun, L, Yang, G, Lu, P, Ma, D, Shi, Y.
Deposit date:2014-08-03
Release date:2014-09-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the gamma-secretase component nicastrin.
Proc.Natl.Acad.Sci.USA, 111, 2014
4UIS
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BU of 4uis by Molmil
The cryoEM structure of human gamma-Secretase complex
Descriptor: GAMMA-SECRETASE, LYSOZYME
Authors:Sun, L, Zhao, L, Yang, G, Yan, C, Zhou, R, Zhou, X, Xie, T, Zhao, Y, Wu, S, Li, X, Shi, Y.
Deposit date:2015-04-03
Release date:2015-06-10
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural Basis of Human Gamma-Secretase Assembly.
Proc.Natl.Acad.Sci.USA, 112, 2015

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