Author results

2CZR
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CRYSTAL STRUCTURE OF TBP-INTERACTING PROTEIN (TK-TIP26) AND IMPLICATIONS FOR ITS INHIBITION MECHANISM OF THE INTERACTION BETWEEN TBP AND TATA-DNA
Descriptor:TBP-interacting protein, ZINC ION, GLYCEROL
Authors:Yamamoto, T., Matsuda, T., Inoue, T., Matsumura, H., Morikawa, M., Kanaya, S., Kai, Y.
Deposit date:2005-07-15
Release date:2006-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of TBP-interacting protein (Tk-TIP26) and implications for its inhibition mechanism of the interaction between TBP and TATA-DNA
Protein Sci., 15, 2006
5F8B
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CRYSTALLOGRAPHIC STRUCTURE OF PSOE WITH CO
Descriptor:Glutathione S-transferase, putative, COBALT (II) ION, ...
Authors:Hara, K., Hashimoto, H., Yamamoto, T., Tsunematsu, Y., Watanabe, K.
Deposit date:2015-12-09
Release date:2016-04-20
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Oxidative trans to cis Isomerization of Olefins in Polyketide Biosynthesis.
Angew. Chem. Int. Ed. Engl., 55, 2016
5FHI
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CRYSTALLOGRAPHIC STRUCTURE OF PSOE WITHOUT CO
Descriptor:Glutathione S-transferase, putative, GLUTATHIONE
Authors:Hara, K., Hashimoto, H., Yamamoto, T., Tsunematsu, Y., Watanabe, K.
Deposit date:2015-12-22
Release date:2016-04-20
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Oxidative trans to cis Isomerization of Olefins in Polyketide Biosynthesis.
Angew. Chem. Int. Ed. Engl., 55, 2016
4X8Y
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CRYSTAL STRUCTURE OF HUMAN PGRMC1 CYTOCHROME B5-LIKE DOMAIN
Descriptor:Membrane-associated progesterone receptor component 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Nakane, T., Yamamoto, T., Shimamura, T., Kobayashi, T., Kabe, Y., Suematsu, M.
Deposit date:2014-12-11
Release date:2016-03-23
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance
Nat Commun, 7, 2016
3WIQ
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CRYSTAL STRUCTURE OF KOJIBIOSE PHOSPHORYLASE COMPLEXED WITH KOJIBIOSE
Descriptor:Kojibiose phosphorylase, ALPHA-D-GLUCOSE, BETA-D-GLUCOSE, ...
Authors:Okada, S., Yamamoto, T., Watanabe, H., Nishimoto, T., Chaen, H., Fukuda, S., Wakagi, T., Fushinobu, S.
Deposit date:2013-09-24
Release date:2014-02-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and mutational analysis of substrate recognition in kojibiose phosphorylase
Febs J., 281, 2014
3WIR
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CRYSTAL STRUCTURE OF KOJIBIOSE PHOSPHORYLASE COMPLEXED WITH GLUCOSE
Descriptor:Kojibiose phosphorylase, BETA-D-GLUCOSE, GLYCEROL, ...
Authors:Okada, S., Yamamoto, T., Watanabe, H., Nishimoto, T., Chaen, H., Fukuda, S., Wakagi, T., Fushinobu, S.
Deposit date:2013-09-24
Release date:2014-02-05
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural and mutational analysis of substrate recognition in kojibiose phosphorylase
Febs J., 281, 2014
2E2G
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CRYSTAL STRUCTURE OF ARCHAEAL PEROXIREDOXIN, THIOREDOXIN PEROXIDASE FROM AEROPYRUM PERNIX K1 (PRE-OXIDATION FORM)
Descriptor:Probable peroxiredoxin
Authors:Nakamura, T., Yamamoto, T., Abe, M., Matsumura, H., Hagihara, Y., Goto, T., Yamaguchi, T., Inoue, T.
Deposit date:2006-11-13
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Oxidation of archaeal peroxiredoxin involves a hypervalent sulfur intermediate
Proc.Natl.Acad.Sci.Usa, 105, 2008
2E2M
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CRYSTAL STRUCTURE OF ARCHAEAL PEROXIREDOXIN, THIOREDOXIN PEROXIDASE FROM AEROPYRUM PERNIX K1 (SULFINIC ACID FORM)
Descriptor:Probable peroxiredoxin
Authors:Nakamura, T., Yamamoto, T., Abe, M., Matsumura, H., Hagihara, Y., Goto, T., Yamaguchi, T., Inoue, T.
Deposit date:2006-11-14
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Oxidation of archaeal peroxiredoxin involves a hypervalent sulfur intermediate
Proc.Natl.Acad.Sci.Usa, 105, 2008
2NVL
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CRYSTAL STRUCTURE OF ARCHAEAL PEROXIREDOXIN, THIOREDOXIN PEROXIDASE FROM AEROPYRUM PERNIX K1 (SULFONIC ACID FORM)
Descriptor:Probable peroxiredoxin
Authors:Nakamura, T., Yamamoto, T., Abe, M., Matsumura, H., Hagihara, Y., Goto, T., Yamaguchi, T., Inoue, T.
Deposit date:2006-11-13
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Oxidation of archaeal peroxiredoxin involves a hypervalent sulfur intermediate
Proc.Natl.Acad.Sci.Usa, 105, 2008
3VQU
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CRYSTAL STRUCTURE OF HUMAN MPS1 CATALYTIC DOMAIN IN COMPLEX WITH 4-[(4-AMINO-5-CYANO-6-ETHOXYPYRIDIN-2- YL)AMINO]BENZAMIDE
Descriptor:Dual specificity protein kinase TTK, IODIDE ION, 4-[(4-amino-5-cyano-6-ethoxypyridin-2-yl)amino]benzamide
Authors:Kusakabe, K., Ide, N., Daigo, Y., Itoh, T., Higashino, K., Okano, Y., Tadano, G., Tachibana, Y., Sato, Y., Inoue, M., Wada, T., Iguchi, M., Kanazawa, T., Ishioka, Y., Dohi, K., Tagashira, S., Kido, Y., Sakamoto, S., Yasuo, K., Maeda, M., Yamamoto, T., Higaki, M., Endoh, T., Ueda, K., Shiota, T., Murai, H., Nakamura, Y.
Deposit date:2012-03-30
Release date:2012-06-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Diaminopyridine-Based Potent and Selective Mps1 Kinase Inhibitors Binding to an Unusual Flipped-Peptide Conformation
ACS MED.CHEM.LETT., 2012
3WZN
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CRYSTAL STRUCTURE OF THE CORE STREPTAVIDIN MUTANT V21 (Y22S/N23D/S27D/Y83S/R84K/E101D/R103K/E116N) COMPLEXED WITH BIOTIN AT 1.3 A RESOLUTION
Descriptor:Streptavidin, BIOTIN, SULFATE ION
Authors:Kawato, T., Mizohata, E., Shimizu, Y., Meshizuka, T., Yamamoto, T., Takasu, N., Matsuoka, M., Matsumura, H., Tsumoto, K., Kodama, T., Kanai, M., Doi, H., Inoue, T., Sugiyama, A.
Deposit date:2014-10-01
Release date:2015-02-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure-based design of a streptavidin mutant specific for an artificial biotin analogue
J.Biochem., 2015
3WZO
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CRYSTAL STRUCTURE OF THE CORE STREPTAVIDIN MUTANT V21 (Y22S/N23D/S27D/Y83S/R84K/E101D/R103K/E116N) COMPLEXED WITH BIOTIN LONG TAIL (BTNTAIL) AT 1.5 A RESOLUTION
Descriptor:Streptavidin, 6-({5-[(3aS,4S,5S,6aR)-5-oxido-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)hexanoic acid, GLYCEROL, ...
Authors:Kawato, T., Mizohata, E., Shimizu, Y., Meshizuka, T., Yamamoto, T., Takasu, N., Matsuoka, M., Matsumura, H., Tsumoto, K., Kodama, T., Kanai, M., Doi, H., Inoue, T., Sugiyama, A.
Deposit date:2014-10-01
Release date:2015-02-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure-based design of a streptavidin mutant specific for an artificial biotin analogue
J.Biochem., 2015
3WZP
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CRYSTAL STRUCTURE OF THE CORE STREPTAVIDIN MUTANT V21 (Y22S/N23D/S27D/Y83S/R84K/E101D/R103K/E116N) COMPLEXED WITH IMINOBIOTIN LONG TAIL (IMNTAIL) AT 1.2 A RESOLUTION
Descriptor:Streptavidin, 6-({5-[(2E,3aS,4S,6aR)-2-iminohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)hexanoic acid, GLYCEROL
Authors:Kawato, T., Mizohata, E., Shimizu, Y., Meshizuka, T., Yamamoto, T., Takasu, N., Matsuoka, M., Matsumura, H., Tsumoto, K., Kodama, T., Kanai, M., Doi, H., Inoue, T., Sugiyama, A.
Deposit date:2014-10-01
Release date:2015-02-18
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure-based design of a streptavidin mutant specific for an artificial biotin analogue
J.Biochem., 2015
3WZQ
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CRYSTAL STRUCTURE OF THE CORE STREPTAVIDIN MUTANT V212 (Y22S/N23D/S27D/S45N/Y83S/R84K/E101D/R103K/E116N) COMPLEXED WITH IMINOBIOTIN LONG TAIL (IMNTAIL) AT 1.7 A RESOLUTION
Descriptor:Streptavidin, 6-({5-[(2E,3aS,4S,6aR)-2-iminohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)hexanoic acid, HEXAETHYLENE GLYCOL
Authors:Kawato, T., Mizohata, E., Shimizu, Y., Meshizuka, T., Yamamoto, T., Takasu, N., Matsuoka, M., Matsumura, H., Tsumoto, K., Kodama, T., Kanai, M., Doi, H., Inoue, T., Sugiyama, A.
Deposit date:2014-10-01
Release date:2015-02-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-based design of a streptavidin mutant specific for an artificial biotin analogue
J.Biochem., 2015
3X00
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CRYSTAL STRUCTURE OF THE CORE STREPTAVIDIN MUTANT V212 (Y22S/N23D/S27D/S45N/Y83S/R84K/E101D/R103K/E116N) COMPLEXED WITH BIS IMINOBIOTIN LONG TAIL (BIS-IMNTAIL) AT 1.3 A RESOLUTION
Descriptor:Streptavidin, 6-({5-[(2E,3aS,4S,6aR)-2-iminohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)hexanoic acid, ETHANE-1,2-DIAMINE
Authors:Kawato, T., Mizohata, E., Shimizu, Y., Meshizuka, T., Yamamoto, T., Takasu, N., Matsuoka, M., Matsumura, H., Kodama, T., Kanai, M., Doi, H., Inoue, T., Sugiyama, A.
Deposit date:2014-10-09
Release date:2015-01-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure-based design and synthesis of a bivalent iminobiotin analog showing strong affinity toward a low immunogenic streptavidin mutant
Biosci.Biotechnol.Biochem., 2015
1X0R
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THIOREDOXIN PEROXIDASE FROM AEROPYRUM PERNIX K1
Descriptor:Probable peroxiredoxin, 1,2-ETHANEDIOL
Authors:Nakamura, T., Yamamoto, T., Inoue, T., Matsumura, H., Kobayashi, A., Hagihara, Y., Uegaki, K., Ataka, M., Kai, Y., Ishikawa, K.
Deposit date:2005-03-28
Release date:2005-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of thioredoxin peroxidase from aerobic hyperthermophilic archaeon Aeropyrum pernix K1
Proteins, 62, 2006
2EB2
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CRYSTAL STRUCTURE OF MUTATED EGFR KINASE DOMAIN (G719S)
Descriptor:Epidermal growth factor receptor
Authors:Yoshikawa, S., Kukimoto-Niino, M., Chen, L., Liu, Z.J., Wang, B.C., Shirouzu, M., Senba, K., Yamamoto, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-06
Release date:2008-02-12
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor
Oncogene, 2012
2EB3
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CRYSTAL STRUCTURE OF MUTATED EGFR KINASE DOMAIN (L858R) IN COMPLEX WITH AMPPNP
Descriptor:Epidermal growth factor receptor, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Yoshikawa, S., Kukimoto-Niino, M., Shirouzu, M., Senba, K., Yamamoto, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-06
Release date:2008-02-12
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor
Oncogene, 2012
2ZCT
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OXIDATION OF ARCHAEAL PEROXIREDOXIN INVOLVES A HYPERVALENT SULFUR INTERMEDIATE
Descriptor:Probable peroxiredoxin
Authors:Nakamura, T., Hagihara, Y., Abe, M., Inoue, T., Yamamoto, T., Matsumura, H.
Deposit date:2007-11-12
Release date:2008-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Oxidation of archaeal peroxiredoxin involves a hypervalent sulfur intermediate
Proc.Natl.Acad.Sci.Usa, 105, 2008
3VJN
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CRYSTAL STRUCTURE OF THE MUTATED EGFR KINASE DOMAIN (G719S/T790M) IN COMPLEX WITH AMPPNP.
Descriptor:Epidermal growth factor receptor, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Yoshikawa, S., Kukimoto-Niino, M., Shirouzu, M., Semba, K., Yamamoto, T., Yokoyama, S.
Deposit date:2011-10-27
Release date:2012-03-07
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor.
Oncogene, 32, 2013
3VJO
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CRYSTAL STRUCTURE OF THE WILD-TYPE EGFR KINASE DOMAIN IN COMPLEX WITH AMPPNP.
Descriptor:Epidermal growth factor receptor, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Yoshikawa, S., Kukimoto-Niino, M., Shirouzu, M., Semba, K., Yamamoto, T., Yokoyama, S.
Deposit date:2011-10-27
Release date:2012-03-07
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor.
Oncogene, 32, 2013
3W1F
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CRYSTAL STRUCTURE OF HUMAN MPS1 CATALYTIC DOMAIN IN COMPLEX WITH 5-(5-ETHOXY-6-(1-METHYL-1H-PYRAZOL-4-YL)-1H-INDAZOL-3-YL)-2-METHYLBENZENESULFONAMIDE
Descriptor:Dual specificity protein kinase TTK, 5-[5-ethoxy-6-(1-methyl-1H-pyrazol-4-yl)-1H-indazol-3-yl]-2-methylbenzenesulfonamide
Authors:Kusakabe, K., Ide, N., Daigo, Y., Tachibana, Y., Itoh, T., Yamamoto, T., Hashizume, H., Hato, Y., Higashino, K., Okano, Y., Sato, Y., Inoue, M., Iguchi, M., Kanazawa, T., Ishioka, Y., Dohi, K., Kido, Y., Sakamoto, S., Yasuo, K., Maeda, M., Higaki, M., Ueda, K., Yoshizawa, H., Baba, Y., Shiota, T., Murai, H., Nakamura, Y.
Deposit date:2012-11-14
Release date:2013-06-26
Last modified:2014-04-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125)
J.Med.Chem., 56, 2013
3WD0
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SERRATIA MARCESCENS CHITINASE B, TETRAGONAL FORM
Descriptor:Chitinase B, GLYCEROL, SULFATE ION, ...
Authors:Hirose, T., Maita, N., Gouda, H., Koseki, J., Yamamoto, T., Sugawara, A., Nakano, H., Hirono, S., Shiomi, K., Watanabe, T., Taniguchi, H., Sharpless, K.B., Omura, S., Sunazuka, T.
Deposit date:2013-06-06
Release date:2013-09-18
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
Proc.Natl.Acad.Sci.USA, 110, 2013
3WD1
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SERRATIA MARCESCENS CHITINASE B COMPLEXED WITH SYN-TRIAZOLE INHIBITOR
Descriptor:Chitinase B, GLYCEROL, SULFATE ION, ...
Authors:Hirose, T., Maita, N., Gouda, H., Koseki, J., Yamamoto, T., Sugawara, A., Nakano, H., Hirono, S., Shiomi, K., Watanabe, T., Taniguchi, H., Sharpless, K.B., Omura, S., Sunazuka, T.
Deposit date:2013-06-06
Release date:2013-09-18
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
Proc.Natl.Acad.Sci.USA, 110, 2013
3WD2
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SERRATIA MARCESCENS CHITINASE B COMPLEXED WITH AZIDE INHIBITOR
Descriptor:Chitinase B, [2-[[(2S)-1-[bis(phenylmethyl)amino]-5-[[N-(methylcarbamoyl)carbamimidoyl]amino]-1-oxidanylidene-pentan-2-yl]amino]-2-oxidanylidene-ethyl]-diazonio-azanide, GLYCEROL, ...
Authors:Hirose, T., Maita, N., Gouda, H., Koseki, J., Yamamoto, T., Sugawara, A., Nakano, H., Hirono, S., Shiomi, K., Watanabe, T., Taniguchi, H., Sharpless, K.B., Omura, S., Sunazuka, T.
Deposit date:2013-06-06
Release date:2013-09-18
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
Proc.Natl.Acad.Sci.USA, 110, 2013