Author results

5Y5D
  • Download 5y5d
  • View 5y5d
Molmil generated image of 5y5d
THE CRYSTAL STRUCTURE OF VREH2 MUTANT M263W
Descriptor:Epoxide hydrolase
Authors:Xu, J.H., Yu, H.L., Zhou, J.H., Kong, X.D., Li, F.L.
Deposit date:2017-08-08
Release date:2018-12-05
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The crystal structure of VrEH2 mutant M263W
To Be Published
5XM6
  • Download 5xm6
  • View 5xm6
Molmil generated image of 5xm6
THE OVERALL STRUCTURE OF VREH2
Descriptor:Epoxide hydrolase
Authors:Li, F.L., Kong, X.D., Yu, H.L., Shang, Y.P., Zhou, J.H., Xu, J.H.
Deposit date:2017-05-12
Release date:2018-09-05
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Regioselectivity Engineering of Epoxide Hydrolase: Near-Perfect Enantioconvergence through a Single Site Mutation
Acs Catalysis, 8, 2018
5Y6Y
  • Download 5y6y
  • View 5y6y
Molmil generated image of 5y6y
THE CRYSTAL STRUCTURE OF VREH2 MUTANT M263N
Descriptor:Epoxide hydrolase
Authors:Li, F.L., Yu, H.L., Chen, Q., Kong, X.D., Zhou, J.H., Xu, J.H.
Deposit date:2017-08-15
Release date:2018-09-05
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Regioselectivity Engineering of Epoxide Hydrolase: Near-Perfect Enantioconvergence through a Single Site Mutation
Acs Catalysis, 8, 2018
5YB5
  • Download 5yb5
  • View 5yb5
Molmil generated image of 5yb5
THE COMPLEX CRYSTAL STRUCTURE OF VREH2 MUTANT M263N WITH SNO
Descriptor:Epoxide hydrolase, (S)-PARA-NITROSTYRENE OXIDE
Authors:Li, F.L., Chen, F.F., Chen, Q., Kong, X.D., Yu, H.L., Xu, J.H.
Deposit date:2017-09-03
Release date:2018-09-05
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Regioselectivity Engineering of Epoxide Hydrolase: Near-Perfect Enantioconvergence through a Single Site Mutation
Acs Catalysis, 8, 2018
4INZ
  • Download 4inz
  • View 4inz
Molmil generated image of 4inz
THE CRYSTAL STRUCTURE OF M145A MUTANT OF AN EPOXIDE HYDROLASE FROM BACILLUS MEGATERIUM
Descriptor:Soluble epoxide hydrolase, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER
Authors:Kong, X.D., Zhou, J.H., Xu, J.H.
Deposit date:2013-01-07
Release date:2014-02-12
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates.
Proc.Natl.Acad.Sci.USA, 111, 2014
4IO0
  • Download 4io0
  • View 4io0
Molmil generated image of 4io0
CRYSTAL STRUCTURE OF F128A MUTANT OF AN EPOXIDE HYDROLASE FROM BACILLUS MEGATERIUM COMPLEXED WITH ITS PRODUCT (R)-3-[1]NAPHTHYLOXY-PROPANE-1,2-DIOL
Descriptor:Soluble epoxide hydrolase, SULFATE ION, (2R)-3-(naphthalen-1-yloxy)propane-1,2-diol
Authors:Kong, X.D., Zhou, J.H., Xu, J.H.
Deposit date:2013-01-07
Release date:2014-02-12
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates.
Proc.Natl.Acad.Sci.USA, 111, 2014
4OB6
  • Download 4ob6
  • View 4ob6
Molmil generated image of 4ob6
COMPLEX STRUCTURE OF ESTERASE RPPE S159A/W187H AND SUBSTRATE (S)-AC-CPA
Descriptor:Alpha/beta hydrolase fold-3 domain protein, (2S)-(acetyloxy)(2-chlorophenyl)ethanoic acid
Authors:Dou, S., Kong, X.D., Ma, B.D., Chen, Q., Zhou, J.H., Xu, J.H.
Deposit date:2014-01-07
Release date:2014-07-23
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
4OB7
  • Download 4ob7
  • View 4ob7
Molmil generated image of 4ob7
CRYSTAL STRUCTURE OF ESTERASE RPPE MUTANT W187H
Descriptor:Alpha/beta hydrolase fold-3 domain protein, (4S)-2-METHYL-2,4-PENTANEDIOL, DI(HYDROXYETHYL)ETHER
Authors:Dou, S., Kong, X.D., Ma, B.D., Xu, J.H., Zhou, J.H.
Deposit date:2014-01-07
Release date:2014-07-23
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
4OB8
  • Download 4ob8
  • View 4ob8
Molmil generated image of 4ob8
CRYSTAL STRUCTURE OF A NOVEL THERMOSTABLE ESTERASE FROM PSEUDOMONAS PUTIDA ECU1011
Descriptor:Alpha/beta hydrolase fold-3 domain protein, (4S)-2-METHYL-2,4-PENTANEDIOL, DI(HYDROXYETHYL)ETHER
Authors:Dou, S., Kong, X.D., Ma, B.D., Xu, J.H., Zhou, J.H.
Deposit date:2014-01-07
Release date:2014-07-23
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
4OU4
  • Download 4ou4
  • View 4ou4
Molmil generated image of 4ou4
CRYSTAL STRUCTURE OF ESTERASE RPPE MUTANT S159A COMPLEXED WITH (S)-AC-CPA
Descriptor:Alpha/beta hydrolase fold-3 domain protein, (2S)-(acetyloxy)(2-chlorophenyl)ethanoic acid
Authors:Dou, S., Kong, X.D., Ma, B.D., Xu, J.H., Zhou, J.H.
Deposit date:2014-02-15
Release date:2014-07-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
4OU5
  • Download 4ou5
  • View 4ou5
Molmil generated image of 4ou5
CRYSTAL STRUCTURE OF ESTERASE RPPE MUTANT S159A/W187H
Descriptor:Alpha/beta hydrolase fold-3 domain protein, (4S)-2-METHYL-2,4-PENTANEDIOL, DI(HYDROXYETHYL)ETHER
Authors:Dou, S., Kong, X.D., Ma, B.D., Xu, J.H., Zhou, J.H.
Deposit date:2014-02-15
Release date:2014-07-23
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
4XUK
  • Download 4xuk
  • View 4xuk
Molmil generated image of 4xuk
CRYSTAL STRUCTURE OF HYDROLASE ABOPH IN BETA LACTAMASE SUPERFAMILY
Descriptor:Putative hydrolase, ZINC ION
Authors:Chen, J., Xu, J.H., Zhou, J.H.
Deposit date:2015-01-26
Release date:2015-10-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Marked enhancement of Acinetobacter sp. organophosphorus hydrolase activity by a single residue substitution Ile211Ala
Bioresour Bioprocess, 2015
5XMD
  • Download 5xmd
  • View 5xmd
Molmil generated image of 5xmd
CRYSTAL STRUCTURE OF EPOXIDE HYDROLASE VREH1 FROM VIGNA RADIATA
Descriptor:Epoxide hydrolase A
Authors:Kong, X.D., Xu, J.H., Zhou, J.H.
Deposit date:2017-05-14
Release date:2018-05-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Carboxyl reductase
to be published
4NZZ
  • Download 4nzz
  • View 4nzz
Molmil generated image of 4nzz
CRYSTAL STRUCTURE OF EPOXIDE HYDROLASE FROM BACILLUS MEGATERIUM
Descriptor:Soluble epoxide hydrolase
Authors:Kong, X.D., Zhou, J.H., Xu, J.H.
Deposit date:2013-12-13
Release date:2014-10-29
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates.
Proc.Natl.Acad.Sci.USA, 111, 2014
4O08
  • Download 4o08
  • View 4o08
Molmil generated image of 4o08
CRYSTAL STRUCTURE OF BACILLUS MEGATERIUM EPOXIDE HYDROLASE IN COMPLEX WITH AN INHIBITOR
Descriptor:Soluble epoxide hydrolase, 2-phenoxyacetamide, SULFATE ION
Authors:Kong, X.D., Zhou, J.H., Xu, J.H.
Deposit date:2013-12-13
Release date:2014-10-29
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates.
Proc.Natl.Acad.Sci.USA, 111, 2014
4O98
  • Download 4o98
  • View 4o98
Molmil generated image of 4o98
CRYSTAL STRUCTURE OF PSEUDOMONAS OLEOVORANS POOPH MUTANT H250I/I263W
Descriptor:organophosphorus hydrolase, ZINC ION
Authors:Luo, X.J., Kong, X.D., Zhao, J., Chen, Q., Zhou, J.H., Xu, J.H.
Deposit date:2014-01-02
Release date:2014-12-03
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.251 Å)
Cite:Switching a newly discovered lactonase into an efficient and thermostable phosphotriesterase by simple double mutations His250Ile/Ile263Trp
Biotechnol.Bioeng., 111, 2014
4EEX
  • Download 4eex
  • View 4eex
Molmil generated image of 4eex
CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS ALCOHOL DEHYDROGENASE
Descriptor:Alcohol dehydrogenase 1, ZINC ION, TETRAETHYLENE GLYCOL
Authors:Liu, X., Bastian, S., Snow, C.D., Brustad, E.M., Saleski, T., Xu, J.H., Meinhold, P., Arnold, F.H.
Deposit date:2012-03-28
Release date:2012-09-26
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-guided engineering of Lactococcus lactis alcohol dehydrogenase LlAdhA for improved conversion of isobutyraldehyde to isobutanol.
J.Biotechnol., 164, 2012
4EEZ
  • Download 4eez
  • View 4eez
Molmil generated image of 4eez
CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS ALCOHOL DEHYDROGENASE VARIANT RE1
Descriptor:Alcohol dehydrogenase 1, ZINC ION, TETRAETHYLENE GLYCOL
Authors:Liu, X., Bastian, S., Snow, C.D., Brustad, E.M., Saleski, T., Xu, J.H., Meinhold, P., Arnold, F.H.
Deposit date:2012-03-28
Release date:2012-09-26
Last modified:2012-11-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-guided engineering of Lactococcus lactis alcohol dehydrogenase LlAdhA for improved conversion of isobutyraldehyde to isobutanol.
J.Biotechnol., 164, 2012
4RNC
  • Download 4rnc
  • View 4rnc
Molmil generated image of 4rnc
CRYSTAL STRUCTURE OF AN ESTERASE RHEST1 FROM RHODOCOCCUS SP. ECU1013
Descriptor:Esterase, PHOSPHATE ION
Authors:Dou, S., Kong, X.D., Xu, J.H., Zhou, J.
Deposit date:2014-10-23
Release date:2015-10-28
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Substrate channel evolution of an esterase for the synthesis of Cilastatin
CATALYSIS SCIENCE AND TECHNOLOGY, 5, 2015
4XBT
  • Download 4xbt
  • View 4xbt
Molmil generated image of 4xbt
CRYSTAL STRUCTURE OF THE L74F/M78F/L103V/L114V/I116V/F139V/L147V MUTANT OF LEH COMPLEXED WITH (S,S)-CYCLOHEXANEDIOL
Descriptor:Limonene-1,2-epoxide hydrolase, (1S,2S)-cyclohexane-1,2-diol, CITRATE ANION
Authors:Kong, X.D., Sun, Z., Lonsdale, R., Xu, J.H., Reetz, M.T., Zhou, J.
Deposit date:2014-12-17
Release date:2015-07-15
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Reshaping an Enzyme Binding Pocket for Enhanced and Inverted Stereoselectivity: Use of Smallest Amino Acid Alphabets in Directed Evolution
Angew.Chem.Int.Ed.Engl., 54, 2015
4XBX
  • Download 4xbx
  • View 4xbx
Molmil generated image of 4xbx
CRYSTAL STRUCTURE OF THE L74F/M78F/L103V/L114V/I116V/F139V/L147V MUTANT OF LEH
Descriptor:Limonene-1,2-epoxide hydrolase
Authors:Kong, X.D., Sun, Z., Xu, J.H., Reetz, M.T., Zhou, J.
Deposit date:2014-12-17
Release date:2015-07-15
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Reshaping an Enzyme Binding Pocket for Enhanced and Inverted Stereoselectivity: Use of Smallest Amino Acid Alphabets in Directed Evolution
Angew.Chem.Int.Ed.Engl., 54, 2015
4XBY
  • Download 4xby
  • View 4xby
Molmil generated image of 4xby
CRYSTAL STRUCTURE OF THE L74F/M78V/I80V/L114F MUTANT OF LEH COMPLEXED WITH CYCLOPENTENE OXIDE
Descriptor:Limonene-1,2-epoxide hydrolase, (1R,5S)-6-oxabicyclo[3.1.0]hexane
Authors:Kong, X.D., Sun, Z., Xu, J.H., Reetz, M.T., Zhou, J.
Deposit date:2014-12-17
Release date:2015-07-15
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Reshaping an Enzyme Binding Pocket for Enhanced and Inverted Stereoselectivity: Use of Smallest Amino Acid Alphabets in Directed Evolution
Angew.Chem.Int.Ed.Engl., 54, 2015
4XDV
  • Download 4xdv
  • View 4xdv
Molmil generated image of 4xdv
CRYSTAL STRUCTURE OF THE L74F/M78V/I80V/L114F MUTANT OF LEH COMPLEXED WITH CYCLOHEXANEDIOL
Descriptor:Limonene-1,2-epoxide hydrolase, (1R,2R)-cyclohexane-1,2-diol
Authors:Kong, X.D., Sun, Z., Lonsdale, R., Xu, J.H., Reetz, M.T., Zhou, J.
Deposit date:2014-12-20
Release date:2015-07-15
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Reshaping an Enzyme Binding Pocket for Enhanced and Inverted Stereoselectivity: Use of Smallest Amino Acid Alphabets in Directed Evolution
Angew.Chem.Int.Ed.Engl., 54, 2015
4XDW
  • Download 4xdw
  • View 4xdw
Molmil generated image of 4xdw
CRYSTAL STRUCTURE OF THE L74F/M78V/I80V/L114F MUTANT OF LEH
Descriptor:Limonene-1,2-epoxide hydrolase
Authors:Kong, X.D., Sun, Z., Lonsdale, R., Xu, J.H., Reetz, M.T., Zhou, J.
Deposit date:2014-12-20
Release date:2015-07-15
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Reshaping an Enzyme Binding Pocket for Enhanced and Inverted Stereoselectivity: Use of Smallest Amino Acid Alphabets in Directed Evolution
Angew.Chem.Int.Ed.Engl., 54, 2015
5EIM
  • Download 5eim
  • View 5eim
Molmil generated image of 5eim
YTH DOMAIN-CONTAINING PROTEIN MMI1 AND RNA COMPLEX
Descriptor:YTH domain-containing protein mmi1, RNA (5'-R(*AP*UP*UP*AP*AP*AP*CP*A)-3')
Authors:Wu, B.X., Xu, J.H., Su, S.C., Ma, J.B.
Deposit date:2015-10-30
Release date:2016-01-27
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural insights into the specific recognition of DSR by the YTH domain containing protein Mmi1
Biochem. Biophys. Res. Commun., 491, 2017
<12>
PDBj@FacebookPDBj@TwitterwwPDBwwPDB Foundation

Copyright © 2013-2019 Protein Data Bank Japan