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4FC8
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BU of 4fc8 by Molmil
Crystal structure of transcription regulator protein Rtr1 from Kluyveromyces lactis
Descriptor: ZINC ION, transcription protein Rtr1
Authors:Xiang, K, Tong, L.
Deposit date:2012-05-24
Release date:2012-07-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The yeast regulator of transcription protein Rtr1 lacks an active site and phosphatase activity.
Nat Commun, 3, 2012
4H3H
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BU of 4h3h by Molmil
Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA poymerase II CTD peptide phosphorylated at SER-7
Descriptor: PHOSPHATE ION, Pol II CTD peptide, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, ...
Authors:Xiang, K, Tong, L.
Deposit date:2012-09-13
Release date:2012-10-31
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72.
Genes Dev., 26, 2012
4H3K
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BU of 4h3k by Molmil
Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA polymerase II CTD peptide phosphorylated at Ser-2, Ser-5 and Ser-7
Descriptor: Hexapeptide, PHOSPHATE ION, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, ...
Authors:Xiang, K, Tong, L.
Deposit date:2012-09-13
Release date:2012-10-31
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72.
Genes Dev., 26, 2012
3O2T
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BU of 3o2t by Molmil
Crystal structure of the N-terminal domain of human Symplekin
Descriptor: 1,2-ETHANEDIOL, Symplekin
Authors:Tong, L, Xiang, K, Xiang, S.
Deposit date:2010-07-22
Release date:2010-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex.
Nature, 467, 2010
3O2Q
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BU of 3o2q by Molmil
Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex
Descriptor: PHOSPHATE ION, RNA polymerase II CTD Serine-5 phosphopeptide, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, ...
Authors:Tong, L, Xiang, K.
Deposit date:2010-07-22
Release date:2010-10-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex.
Nature, 467, 2010
3ODS
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BU of 3ods by Molmil
Crystal structure of the K185A mutant of the N-terminal domain of human Symplekin
Descriptor: 1,2-ETHANEDIOL, Symplekin
Authors:Tong, L, Xiang, K.
Deposit date:2010-08-11
Release date:2010-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex.
Nature, 467, 2010
3O2S
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BU of 3o2s by Molmil
Crystal structure of the human symplekin-Ssu72 complex
Descriptor: PHOSPHATE ION, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, Symplekin
Authors:Tong, L, Xiang, K.
Deposit date:2010-07-22
Release date:2010-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex.
Nature, 467, 2010
3ODR
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BU of 3odr by Molmil
Crystal Structure of the N-terminal Domain of Human Symplekin
Descriptor: 1,2-ETHANEDIOL, Symplekin
Authors:Tong, L, Xiang, K.
Deposit date:2010-08-11
Release date:2010-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex.
Nature, 467, 2010
6EG3
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BU of 6eg3 by Molmil
Crystal structure of human BRM in complex with compound 15
Descriptor: 3-[(4-{[(2-chloropyridin-4-yl)carbamoyl]amino}pyridin-2-yl)ethynyl]benzoic acid, ETHANOL, Maltose/maltodextrin-binding periplasmic protein,Probable global transcription activator SNF2L2
Authors:Zhu, X, Kulathila, R, Hu, T, Xie, X.
Deposit date:2018-08-17
Release date:2018-10-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers.
J. Med. Chem., 61, 2018
6EG2
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BU of 6eg2 by Molmil
Crystal structure of human BRM in complex with compound 16
Descriptor: ISOPROPYL ALCOHOL, Maltose/maltodextrin-binding periplasmic protein,Probable global transcription activator SNF2L2, N-(5-amino-2-chloropyridin-4-yl)-N'-(4-bromo-3-{[3-(hydroxymethyl)phenyl]ethynyl}-1,2-thiazol-5-yl)urea
Authors:Zhu, X, Kulathila, R, Hu, T, Xie, X.
Deposit date:2018-08-17
Release date:2018-10-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers.
J. Med. Chem., 61, 2018
3PIF
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BU of 3pif by Molmil
Crystal structure of the 5'->3' exoribonuclease Xrn1, E178Q mutant in Complex with Manganese
Descriptor: 5'->3' EXORIBONUCLEASE (xrn1), MANGANESE (II) ION
Authors:Chang, J.H, Xiang, S, Tong, L.
Deposit date:2010-11-06
Release date:2011-02-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Structural and biochemical studies of the 5' -> 3' exoribonuclease Xrn1.
Nat.Struct.Mol.Biol., 18, 2011
3PIE
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BU of 3pie by Molmil
Crystal structure of the 5'->3' exoribonuclease Xrn1, E178Q mutant
Descriptor: 5'->3' EXORIBONUCLEASE (Xrn1)
Authors:Chang, J.H, Xiang, S, Tong, L.
Deposit date:2010-11-06
Release date:2011-02-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and biochemical studies of the 5' -> 3' exoribonuclease Xrn1.
Nat.Struct.Mol.Biol., 18, 2011
1WP8
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BU of 1wp8 by Molmil
crystal structure of Hendra Virus fusion core
Descriptor: Fusion glycoprotein F0,Fusion glycoprotein F0
Authors:Xu, Y, Liu, Y, Lou, Z, Su, N, Bai, Z, Gao, G.F, Rao, Z.
Deposit date:2004-08-31
Release date:2005-11-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of Nipah and Hendra virus fusion core proteins
FEBS J., 273, 2006

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