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1N8J
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BU of 1n8j by Molmil
Crystal Structure of AhpC with Active Site Cysteine mutated to Serine (C46S)
Descriptor: Alkyl hydroperoxide reductase C22 protein
Authors:Wood, Z.A, Poole, L.B, Karplus, P.A.
Deposit date:2002-11-20
Release date:2003-04-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Peroxiredoxin Evolution and the Regulation of Hydrogen Peroxide Signaling
Science, 300, 2003
1HYU
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BU of 1hyu by Molmil
CRYSTAL STRUCTURE OF INTACT AHPF
Descriptor: ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT F, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Wood, Z.A, Poole, L.B, Karplus, P.A.
Deposit date:2001-01-22
Release date:2001-02-14
Last modified:2012-05-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of intact AhpF reveals a mirrored thioredoxin-like active site and implies large domain rotations during catalysis.
Biochemistry, 40, 2001
2EWN
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BU of 2ewn by Molmil
Ecoli Biotin Repressor with co-repressor analog
Descriptor: ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE, BirA bifunctional protein
Authors:Wood, Z.A, Weaver, L.H, Matthews, B.W.
Deposit date:2005-11-04
Release date:2006-02-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Co-repressor Induced Order and Biotin Repressor Dimerization: A Case for Divergent Followed by Convergent Evolution.
J.Mol.Biol., 357, 2006
6OID
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BU of 6oid by Molmil
Redox Regulation of FN3K from Arabidopsis thaliana
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
Authors:Wood, Z.A, Kadirvelraj, R, Shrestha, S.
Deposit date:2019-04-09
Release date:2020-05-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.365 Å)
Cite:A redox-active switch in fructosamine-3-kinases expands the regulatory repertoire of the protein kinase superfamily.
Sci.Signal., 13, 2020
4GLL
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BU of 4gll by Molmil
Crystal structure of human UDP-xylose synthase.
Descriptor: GUANIDINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ...
Authors:Wood, Z.A, Polizzi, S.J.
Deposit date:2012-08-14
Release date:2012-09-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Human UDP-alpha-d-xylose Synthase and Escherichia coli ArnA Conserve a Conformational Shunt That Controls Whether Xylose or 4-Keto-Xylose Is Produced.
Biochemistry, 51, 2012
6MW5
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BU of 6mw5 by Molmil
UDP-galactose:glucoside-Skp1 alpha-D-galactosyltransferase with bound UDP and Platinum
Descriptor: 1,2-ETHANEDIOL, PLATINUM (II) ION, UDP-galactose:glucoside-Skp1 alpha-D-galactosyltransferase, ...
Authors:Kim, H.W, Wood, Z.A, West, C.M.
Deposit date:2018-10-29
Release date:2019-10-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A terminal alpha 3-galactose modification regulates an E3 ubiquitin ligase subunit in Toxoplasma gondii .
J.Biol.Chem., 295, 2020
6MW8
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BU of 6mw8 by Molmil
UDP-galactose:glucoside-Skp1 alpha-D-galactosyltransferase with bound UDP and Manganese
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, MANGANESE (II) ION, ...
Authors:Kim, H.W, Wood, Z.A, West, C.M.
Deposit date:2018-10-29
Release date:2019-10-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.756 Å)
Cite:A terminal alpha 3-galactose modification regulates an E3 ubiquitin ligase subunit in Toxoplasma gondii .
J.Biol.Chem., 295, 2020
1T8G
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BU of 1t8g by Molmil
Crystal structure of phage T4 lysozyme mutant L32A/L33A/T34A/C54T/C97A/E108V
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme, ...
Authors:He, M.M, Wood, Z.A, Baase, W.A, Xiao, H, Matthews, B.W.
Deposit date:2004-05-12
Release date:2004-10-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation.
Protein Sci., 13, 2004
1T8F
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BU of 1t8f by Molmil
Crystal structure of phage T4 lysozyme mutant R14A/K16A/I17A/K19A/T21A/E22A/C54T/C97A
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme
Authors:He, M.M, Wood, Z.A, Baase, W.A, Xiao, H, Matthews, B.W.
Deposit date:2004-05-12
Release date:2004-10-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation.
Protein Sci., 13, 2004
4YCA
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BU of 4yca by Molmil
Evidence of Kinetic Cooperativity in dimeric Ketopantoate Reductase from Staphylococcus aureus
Descriptor: 2-dehydropantoate 2-reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sanchez, J.E, Gross, P.G, Goetze, R, Walsh Jr, R.M, Peeples, W.B, Wood, Z.A.
Deposit date:2015-02-19
Release date:2015-03-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Evidence of Kinetic Cooperativity in Dimeric Ketopantoate Reductase from Staphylococcus aureus.
Biochemistry, 54, 2015
4RJT
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BU of 4rjt by Molmil
Crystal Structure of Unliganded, Full Length hUGDH at pH 7.0
Descriptor: CHLORIDE ION, UDP-glucose 6-dehydrogenase
Authors:Sidlo, A.M, Wood, Z.A.
Deposit date:2014-10-09
Release date:2014-12-31
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Hysteresis in Human UDP-Glucose Dehydrogenase Is Due to a Restrained Hexameric Structure That Favors Feedback Inhibition.
Biochemistry, 53, 2014
4S3M
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BU of 4s3m by Molmil
Evidence of kinetic cooperativity in dimeric Ketopantoate Reductase from Staphylococcus aureus
Descriptor: 2-dehydropantoate 2-reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sanchez, J.E, Walsh Jr, R.M, Wood, Z.A.
Deposit date:2015-02-19
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Evidence of Kinetic Cooperativity in Dimeric Ketopantoate Reductase from Staphylococcus aureus.
Biochemistry, 54, 2015
3TF5
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BU of 3tf5 by Molmil
Structure of UDP-glucose dehydrogenase V132 deletion
Descriptor: UDP-glucose 6-dehydrogenase
Authors:Sennett, N.C, Wood, Z.A.
Deposit date:2011-08-15
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conformational flexibility in the allosteric regulation of human UDP-{alpha}-D-glucose 6-dehydrogenase.
Biochemistry, 50, 2011
8D0O
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BU of 8d0o by Molmil
Human alpha1,3-fucosyltransferase FUT9, heavy atom derivative
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, CESIUM ION, ...
Authors:Kadirvelraj, R, Wood, Z.A.
Deposit date:2022-05-26
Release date:2023-05-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9.
Nat.Chem.Biol., 19, 2023
8D0W
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BU of 8d0w by Molmil
Human FUT9 bound to H-Type 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GLYCEROL, ...
Authors:Kadirvelraj, R, Wood, Z.A.
Deposit date:2022-05-26
Release date:2023-05-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.332 Å)
Cite:Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9.
Nat.Chem.Biol., 19, 2023
8D0U
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BU of 8d0u by Molmil
Human FUT9 bound to GDP
Descriptor: 1,2-ETHANEDIOL, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Kadirvelraj, R, Wood, Z.A.
Deposit date:2022-05-26
Release date:2023-05-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9.
Nat.Chem.Biol., 19, 2023
8D0R
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BU of 8d0r by Molmil
Human FUT9 bound to GDP and H-Type 2
Descriptor: 1,2-ETHANEDIOL, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Kadirvelraj, R, Wood, Z.A.
Deposit date:2022-05-26
Release date:2023-05-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9.
Nat.Chem.Biol., 19, 2023
8D0S
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BU of 8d0s by Molmil
Human FUT9 bound to GDP and LNnT
Descriptor: 1,2-ETHANEDIOL, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Kadirvelraj, R, Wood, Z.A.
Deposit date:2022-05-26
Release date:2023-05-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9.
Nat.Chem.Biol., 19, 2023
8D0X
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BU of 8d0x by Molmil
Human FUT9 bound to LNnT
Descriptor: 1,2-ETHANEDIOL, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GLYCEROL, ...
Authors:Kadirvelraj, R, Wood, Z.A.
Deposit date:2022-05-26
Release date:2023-05-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9.
Nat.Chem.Biol., 19, 2023
8D0P
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BU of 8d0p by Molmil
Human FUT9, unliganded
Descriptor: 1,2-ETHANEDIOL, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, SULFATE ION, ...
Authors:Kadirvelraj, R, Wood, Z.A.
Deposit date:2022-05-26
Release date:2023-05-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9.
Nat.Chem.Biol., 19, 2023
8D0Q
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BU of 8d0q by Molmil
Human FUT9 bound to GDP-CF3-Fucose and H-Type 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Kadirvelraj, R, Wood, Z.A.
Deposit date:2022-05-26
Release date:2023-05-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9.
Nat.Chem.Biol., 19, 2023
6OM8
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BU of 6om8 by Molmil
Caenorhabditis Elegans UDP-Glucose Dehydrogenase in complex with UDP-Xylose
Descriptor: UDP-glucose 6-dehydrogenase, URIDINE-5'-DIPHOSPHATE-XYLOPYRANOSE
Authors:Beattie, N.R, McDonald, W.E, Hicks Sirmans, T.N, Wood, Z.A.
Deposit date:2019-04-18
Release date:2019-05-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.449 Å)
Cite:Conservation of Atypical Allostery inC. elegansUDP-Glucose Dehydrogenase.
Acs Omega, 4, 2019
6C4J
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BU of 6c4j by Molmil
Ligand bound full length hUGDH with A104L substitution
Descriptor: CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, S-1,2-PROPANEDIOL, ...
Authors:Beattie, N.R, Pioso, B.J, Wood, Z.A, Sidlo, A.M.
Deposit date:2018-01-12
Release date:2018-05-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Hysteresis and Allostery in Human UDP-Glucose Dehydrogenase Require a Flexible Protein Core.
Biochemistry, 57, 2018
6C5A
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BU of 6c5a by Molmil
Human UDP-Glucose Dehydrogenase with UDP- Glc and NADH bound
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE, UDP-glucose 6-dehydrogenase, ...
Authors:Gross, P.G, Fallah, J, Wood, Z.A.
Deposit date:2018-01-15
Release date:2019-01-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The A225L Substitution of hUGDH alters structure and function
To Be Published
6C58
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BU of 6c58 by Molmil
Human UDP-Glucose Dehydrogenase A225L substitutuion with UDP-xylose bound
Descriptor: CHLORIDE ION, UDP-glucose 6-dehydrogenase, URIDINE-5'-DIPHOSPHATE-XYLOPYRANOSE
Authors:Gross, P.G, Fallah, J, Wood, Z.A.
Deposit date:2018-01-15
Release date:2019-01-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:The A225L Substitution of hUGDH alters structure and function
To Be Published

 

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