Author results

5MCP
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STRUCTURE OF IMP DEHYDROGENASE FROM ASHBYA GOSSYPII BOUND TO ATP
Descriptor:Inosine-5'-monophosphate dehydrogenase, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Winter, G., Fernandez-Justel, D., de Pereda, J.M., Revuelta, J.L., Buey, R.M.
Deposit date:2016-11-10
Release date:2017-06-14
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A nucleotide-controlled conformational switch modulates the activity of eukaryotic IMP dehydrogenases.
Sci Rep, 7, 2017
4S1K
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STRUCTURE OF URANOTAENIA SAPPHIRINA CYPOVIRUS (CPV17) POLYHEDRIN AT 100 K
Descriptor:Polyhedrin, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Ginn, H.M., Messerschmidt, M., Ji, X., Zhang, H., Axford, D., Gildea, R.J., Winter, G., Brewster, A.S., Hattne, J., Wagner, A., Grimes, J.M., Evans, G., Sauter, N.K., Sutton, G., Stuart, D.I.
Deposit date:2015-01-14
Release date:2015-03-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data.
Nat Commun, 6, 2015
4S1L
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STRUCTURE OF URANOTAENIA SAPPHIRINA CYPOVIRUS (CPV17) POLYHEDRIN AT 298 K
Descriptor:polyhedrin, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Ginn, H.M., Messerschmidt, M., Ji, X., Zhang, H., Axford, D., Gildea, R.J., Winter, G., Brewster, A.S., Hattne, J., Wagner, A., Grimes, J.M., Evans, G., Sauter, N.K., Sutton, G., Stuart, D.I.
Deposit date:2015-01-14
Release date:2015-03-25
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.752 Å)
Cite:Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data.
Nat Commun, 6, 2015
3QN7
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POTENT AND SELECTIVE BICYCLIC PEPTIDE INHIBITOR (UK18) OF HUMAN UROKINASE-TYPE PLASMINOGEN ACTIVATOR(UPA)
Descriptor:Urokinase-type plasminogen activator, Bicyclic peptide inhibitor, 1,3,5-tris(bromomethyl)benzene
Authors:Angelini, A., Cendron, L., Touati, J., Winter, G., Zanotti, G., Heinis, C.
Deposit date:2011-02-08
Release date:2012-02-15
Last modified:2013-04-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Bicyclic peptide inhibitor reveals large contact interface with a protease target
Acs Chem.Biol., 7, 2012
1A7N
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FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) VARIANT FOR CHAIN L GLU81->ASP AND CHAIN H LEU312->VAL
Descriptor:IGG1-KAPPA D1.3 FV (LIGHT CHAIN), IGG1-KAPPA D1.3 FV (HEAVY CHAIN)
Authors:Marks, C., Henrick, K., Winter, G.
Deposit date:1998-03-16
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:X-Ray Structures of D1.3 Fv Mutants
To be Published
1A7O
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FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) R96L DELETION MUTANT ON VARIANT FOR CHAIN L GLU81->ASP AND CHAIN H LEU312->VAL
Descriptor:IGG1-KAPPA D1.3 FV (LIGHT CHAIN), IGG1-KAPPA D1.3 FV (HEAVY CHAIN)
Authors:Marks, C., Henrick, K., Winter, G.
Deposit date:1998-03-16
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-Ray Structures of D1.3 Fv Mutants
To be Published
1A7P
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FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) ENGINEERED MUTANT PRO95L->SER ON VARIANT CHAIN L GLU81->ASP AND CHAIN H LEU312->VAL
Descriptor:IGG1-KAPPA D1.3 FV (LIGHT CHAIN), IGG1-KAPPA D1.3 FV (HEAVY CHAIN), ACETIC ACID
Authors:Marks, C., Henrick, K., Winter, G.
Deposit date:1998-03-16
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:X-Ray Structures of D1.3 Fv Mutants
To be Published
1A7Q
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FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) HIGH AFFINITY EXPRESSED VARIANT CONTAINING SER26L->GLY, ILE29L->THR, GLU81L->ASP, THR97L->SER, PRO240H->LEU, ASP258H->ALA, LYS281H->GLU, ASN283H->ASP AND LEU312H->VAL
Descriptor:IGG1-KAPPA D1.3 FV (LIGHT CHAIN), IGG1-KAPPA D1.3 FV (HEAVY CHAIN)
Authors:Marks, C., Henrick, K., Winter, G.
Deposit date:1998-03-16
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-Ray Structures of D1.3 Fv Mutants
To be Published
1A7R
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FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) VARIANT CHAIN L GLU81->ASP
Descriptor:IGG1-KAPPA D1.3 FV (LIGHT CHAIN), IGG1-KAPPA D1.3 FV (HEAVY CHAIN)
Authors:Marks, C., Henrick, K., Winter, G.
Deposit date:1998-03-16
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:X-Ray Structures of D1.3 Fv Mutants
To be Published
1A6U
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B1-8 FV FRAGMENT
Descriptor:B1-8 FV (LIGHT CHAIN), B1-8 FV (HEAVY CHAIN)
Authors:Simon, T., Henrick, K., Hirshberg, M., Winter, G.
Deposit date:1998-03-03
Release date:1998-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-Ray Structures of Fv Fragment and its (4-Hydroxy-3-Nitrophenyl)Acetate Complex of Murine B1-8 Antibody
To be Published
1A6V
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B1-8 FV FRAGMENT COMPLEXED WITH A (4-HYDROXY-3-NITROPHENYL) ACETATE COMPOUND
Descriptor:B1-8 FV (LIGHT CHAIN), B1-8 FV (HEAVY CHAIN), 4-HYDROXY-3-NITROPHENYLACETYL-EPSILON-AMINOCAPROIC ACID ANION
Authors:Simon, T., Henrick, K., Hirshberg, M., Winter, G.
Deposit date:1998-03-03
Release date:1998-07-15
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-Ray Structures of Fv Fragment and its (4-Hydroxy-3-Nitrophenyl)Acetate Complex of Murine B1-8 Antibody
To be Published
1A6W
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B1-8 FV FRAGMENT COMPLEXED WITH A (4-HYDROXY-5-IODO-3-NITROPHENYL) ACETATE COMPOUND
Descriptor:B1-8 FV (LIGHT CHAIN), B1-8 FV (HEAVY CHAIN), 4-HYDROXY-5-IODO-3-NITROPHENYLACETYL-EPSILON-AMINOCAPROIC ACID ANION
Authors:Simon, T., Henrick, K., Hirshberg, M., Winter, G.
Deposit date:1998-03-03
Release date:1998-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-Ray Structures of Fv Fragment and its (4-Hydroxy-3-Nitrophenyl)Acetate Complex of Murine B1-8 Antibody
To be Published
1OHQ
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CRYSTAL STRUCTURE OF HEL4, A SOLUBLE HUMAN VH ANTIBODY DOMAIN RESISTANT TO AGGREGATION
Descriptor:IMMUNOGLOBULIN
Authors:Jespers, L., Schon, O., James, L.C., Veprintsev, D., Winter, G.
Deposit date:2003-05-30
Release date:2004-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Hel4, a Soluble, Refoldable Human V(H) Single Domain with a Germ-Line Scaffold
J.Mol.Biol., 337, 2004
2BH8
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COMBINATORIAL PROTEIN 1B11
Descriptor:1B11
Authors:De Bono, S., Riechmann, L., Girard, E., Williams, R.L., Winter, G.
Deposit date:2005-01-07
Release date:2005-02-07
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Segment of Cold Shock Protein Directs the Folding of a Combinatorial Protein
Proc.Natl.Acad.Sci.USA, 102, 2005
2JCB
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THE CRYSTAL STRUCTURE OF 5-FORMYL-TETRAHYDROFOLATE CYCLOLIGASE FROM BACILLUS ANTHRACIS (BA4489)
Descriptor:5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE FAMILY PROTEIN, ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ...
Authors:Meier, C., Carter, L.G., Winter, G., Owens, R.J., Stuart, D.I., Esnouf, R.M., Oxford Protein Production Facility (OPPF), Structural Proteomics in Europe (SPINE)
Deposit date:2006-12-21
Release date:2007-02-20
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of 5-Formyltetrahydrofolate Cyclo-Ligase from Bacillus Anthracis (Ba4489).
Acta Crystallogr.,Sect.F, 63, 2007
3RZE
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STRUCTURE OF THE HUMAN HISTAMINE H1 RECEPTOR IN COMPLEX WITH DOXEPIN
Descriptor:Histamine H1 receptor, Lysozyme chimera, (3E)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, ...
Authors:Shimamura, T., Han, G.W., Shiroishi, M., Weyand, S., Tsujimoto, H., Winter, G., Katritch, V., Abagyan, R., Cherezov, V., Liu, W., Kobayashi, T., Stevens, R., Iwata, S., GPCR Network (GPCR)
Deposit date:2011-05-11
Release date:2011-06-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the human histamine H1 receptor complex with doxepin.
Nature, 475, 2011
4TWT
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HUMAN TNFA DIMER IN COMPLEX WITH THE SEMI-SYNTHETIC BICYCLIC PEPTIDE M21
Descriptor:Tumor necrosis factor, ALA-CYS-PRO-PRO-CYS-LEU-TRP-GLN-VAL-LEU-CYS-GLY, GLYCEROL, ...
Authors:Luzi, S., Kondo, Y., Bernard, E., Stadler, L., Winter, G., Holliger, P.
Deposit date:2014-07-01
Release date:2015-02-04
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Subunit disassembly and inhibition of TNF alpha by a semi-synthetic bicyclic peptide.
Protein Eng.Des.Sel., 28, 2015
6RVO
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MULTICRYSTAL DATASET OF THAUMATIN COLLECTED USING A MULTILAYER MONOCHROMATOR.
Descriptor:Thaumatin I, L(+)-TARTARIC ACID
Authors:Sandy, J., Sanchez-Weatherby, J., Mikolajek, H., Winter, G.
Deposit date:2019-05-31
Release date:2019-06-19
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:VMXi - Fully automated data collection at room temperature.
To Be Published
4R8J
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D(TCGGCGCCGA) WITH LAMBDA-[RU(TAP)2(DPPZ)]2+ SOAKED IN D2O
Descriptor:DNA (5'-D(*(THM)P*CP*GP*GP*CP*GP*CP*CP*GP*A)-3'), BARIUM ION, Ru(tap)2(dppz) complex, ...
Authors:Hall, J.P., Gurung, S.P., Winter, G.W., Cardin, C.J.
Deposit date:2014-09-02
Release date:2015-10-28
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy.
Nat Chem, 7, 2015
1TYA
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STRUCTURAL ANALYSIS OF A SERIES OF MUTANTS OF TYROSYL-TRNA SYNTHETASE: ENHANCEMENT OF CATALYSIS BY HYDROPHOBIC INTERACTIONS
Descriptor:TYROSYL-tRNA SYNTHETASE, TYROSINE
Authors:Brown, K.A., De Meester, P., Blow, D.M.
Deposit date:1992-07-06
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Analysis of a Series of Mutants of Tyrosyl-tRNA Synthetase: Enhancement of Catalysis by Hydrophobic Interactions
To be Published
1TYB
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STRUCTURAL ANALYSIS OF A SERIES OF MUTANTS OF TYROSYL-TRNA SYNTHETASE: ENHANCEMENT OF CATALYSIS BY HYDROPHOBIC INTERACTIONS
Descriptor:TYROSYL-tRNA SYNTHETASE, TYROSINE
Authors:Brown, K.A., De Meester, P., Blow, D.M.
Deposit date:1992-07-06
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Analysis of a Series of Mutants of Tyrosyl-tRNA Synthetase: Enhancement of Catalysis by Hydrophobic Interactions
To be Published
1TYC
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STRUCTURAL ANALYSIS OF A SERIES OF MUTANTS OF TYROSYL-TRNA SYNTHETASE: ENHANCEMENT OF CATALYSIS BY HYDROPHOBIC INTERACTIONS
Descriptor:TYROSYL-tRNA SYNTHETASE
Authors:Brown, K.A., Brick, P., De Meester, P., Blow, D.M.
Deposit date:1992-07-06
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Analysis of a Series of Mutants of Tyrosyl-tRNA Synthetase: Enhancement of Catalysis by Hydrophobic Interactions
To be Published
1TYD
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STRUCTURE OF TYROSYL-TRNA SYNTHETASE REFINED AT 2.3 ANGSTROMS RESOLUTION. INTERACTION OF THE ENZYME WITH THE TYROSYL ADENYLATE INTERMEDIATE
Descriptor:TYROSYL-tRNA SYNTHETASE, TYROSINE
Authors:Brown, K.A., De Meester, P., Blow, D.M.
Deposit date:1992-07-06
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of tyrosyl-tRNA synthetase refined at 2.3 A resolution. Interaction of the enzyme with the tyrosyl adenylate intermediate.
J.Mol.Biol., 208, 1989
1LMK
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THE STRUCTURE OF A BIVALENT DIABODY
Descriptor:ANTI-PHOSPHATIDYLINOSITOL SPECIFIC PHOSPHOLIPASE C DIABODY
Authors:Williams, R.L.
Deposit date:1994-08-29
Release date:1995-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a diabody, a bivalent antibody fragment.
Structure, 2, 1994
2BX5
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IS FR1 THE ANTIBODY'S ACHILLIES HEEL
Descriptor:VD9 VKI LIGHT-CHAIN
Authors:James, L.C.
Deposit date:2005-07-22
Release date:2006-11-15
Last modified:2014-01-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Beta-Edge Interactions in a Pentadecameric Human Antibody Vkappa Domain.
J.Mol.Biol., 367, 2007
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