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6DTE
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GlcNAc-inspired cyclophellitol bound to NagZ
Descriptor: 2,2,2-trifluoro-N-[(1R,2R,3R,4R,5R,6R)-2,3,5,6-tetrahydroxy-4-(hydroxymethyl)cyclohexyl]acetamide, Beta-hexosaminidase
Authors:Mark, B.L, Winogrodzki, J.L.
Deposit date:2018-06-15
Release date:2019-04-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.929 Å)
Cite:A mechanism-based GlcNAc-inspired cyclophellitol inactivator of the peptidoglycan recycling enzyme NagZ reverses resistance to beta-lactams in Pseudomonas aeruginosa.
Chem. Commun. (Camb.), 54, 2018

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