Author results

2ADA
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ATOMIC STRUCTURE OF ADENOSINE DEAMINASE COMPLEXED WITH A TRANSITION-STATE ANALOG: UNDERSTANDING CATALYSIS AND IMMUNODEFICIENCY MUTATIONS
Descriptor:ADENOSINE DEAMINASE, ZINC ION, 6-HYDROXY-7,8-DIHYDRO PURINE NUCLEOSIDE
Authors:Wilson, D.K., Quiocho, F.A.
Deposit date:1994-12-02
Release date:1995-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Atomic structure of adenosine deaminase complexed with a transition-state analog: understanding catalysis and immunodeficiency mutations.
Science, 252, 1991
1ADD
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A PRE-TRANSITION STATE MIMIC OF AN ENZYME: X-RAY STRUCTURE OF ADENOSINE DEAMINASE WITH BOUND 1-DEAZA-ADENOSINE AND ZINC-ACTIVATED WATER
Descriptor:ADENOSINE DEAMINASE, ZINC ION, 1-DEAZA-ADENOSINE
Authors:Wilson, D.K., Quiocho, F.A.
Deposit date:1992-12-22
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A pre-transition-state mimic of an enzyme: X-ray structure of adenosine deaminase with bound 1-deazaadenosine and zinc-activated water.
Biochemistry, 32, 1993
1MAR
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REFINED 1.8 ANGSTROMS STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH THE POTENT INHIBITOR ZOPOLRESTAT
Descriptor:ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID
Authors:Wilson, D.K., Quiocho, F.A.
Deposit date:1993-07-20
Release date:1995-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Refined 1.8 A structure of human aldose reductase complexed with the potent inhibitor zopolrestat.
Proc.Natl.Acad.Sci.USA, 90, 1993
1ADS
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AN UNLIKELY SUGAR SUBSTRATE SITE IN THE 1.65 ANGSTROMS STRUCTURE OF THE HUMAN ALDOSE REDUCTASE HOLOENZYME IMPLICATED IN DIABETIC COMPLICATIONS
Descriptor:ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wilson, D.K., Quiocho, F.A.
Deposit date:1992-07-08
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:An unlikely sugar substrate site in the 1.65 A structure of the human aldose reductase holoenzyme implicated in diabetic complications.
Science, 257, 1992
1FRB
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FR-1 PROTEIN/NADPH/ZOPOLRESTAT COMPLEX
Descriptor:FR-1 PROTEIN, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID
Authors:Wilson, D.K., Quiocho, F.A.
Deposit date:1995-08-08
Release date:1996-10-14
Last modified:2013-12-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:1.7 A structure of FR-1, a fibroblast growth factor-induced member of the aldo-keto reductase family, complexed with coenzyme and inhibitor.
Biochemistry, 34, 1995
1YFQ
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HIGH RESOLUTION S. CEREVISIAE BUB3 MITOTIC CHECKPOINT PROTEIN
Descriptor:Cell cycle arrest protein BUB3, CALCIUM ION, ACETATE ION
Authors:Wilson, D.K., Cerna, D., Chew, E.
Deposit date:2005-01-03
Release date:2005-01-11
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The 1.1-a structure of the spindle checkpoint protein bub3p reveals functional regions.
J.Biol.Chem., 280, 2005
3CZM
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T. GONDII BRADYZOITE-SPECIFIC LDH (LDH2) IN COMPLEX WITH NAD AND OXQ
Descriptor:L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 4-HYDROXY-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID
Authors:Wilson, D.K., Susko, M.S.
Deposit date:2008-04-29
Release date:2009-06-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:T. Gondii bradyzoite-specific LDH (LDH2) in complex with NAD and OXQ
To be Published
5UWZ
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PROTEIN 12 WITH ALDEHYDE DEFORMYLATING OXYGENASE ACTIVITY FROM GLOEOBACTER VIOLACEUS
Descriptor:Aldehyde decarbonylase, 1,2-ETHANEDIOL, STEARIC ACID
Authors:Wilson, D.K.
Deposit date:2017-02-21
Release date:2018-02-28
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Protein 12 with aldehyde deformylating oxygenase activity from Gloeobacter violaceus
To Be Published
5UX1
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PROTEIN 43 WITH ALDEHYDE DEFORMYLATING OXYGENASE ACTIVITY FROM SYNECHOCOCCUS
Descriptor:tRNA-(MS(2)IO(6)A)-hydroxylase-like, FE (III) ION
Authors:Wilson, D.K., Mak, W.S., Siegel, J.B.
Deposit date:2017-02-21
Release date:2018-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Protein 43 with aldehyde deformylating oxygenase activity from Synechococcus
To Be Published
5UX2
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PROTEIN 19 WITH ALDEHYDE DEFORMYLATING OXIDASE ACTIVITY FROM SYNECHOCOCCUS
Descriptor:Aldehyde decarbonylase, FE (III) ION, PROPANOIC ACID
Authors:Wilson, D.K., Mak, W.S., Siegel, J.B.
Deposit date:2017-02-21
Release date:2018-02-28
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Protein 19 with aldehyde deformylating oxidase activity from Synechococcus
To Be Published
5UXG
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PROTEIN 84 WITH ALDEHYDE DEFORMYLATING OXYGENASE ACTIVITY FROM SULFOLOBUS TOKODAII (MONOCLINIC)
Descriptor:aldehyde deformylating oxygenase, PHOSPHATE ION
Authors:Wilson, D.K., Mak, W.S., Siegel, J.B.
Deposit date:2017-02-22
Release date:2018-02-28
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Protein 84 with aldehyde deformylating oxygenase activity from Sulfolobus tokodaii (monoclinic)
To Be Published
5UXI
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PROTEIN 4 WITH ALDEHYDE DEFORMYLATING OXYGENASE ACTIVITY FROM NOSTOC PUNTIFORME
Descriptor:Aldehyde decarbonylase, DECYLAMINE-N,N-DIMETHYL-N-OXIDE
Authors:Wilson, D.K., Mak, W.S., Siegel, J.B.
Deposit date:2017-02-22
Release date:2018-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Protein 4 with aldehyde deformylating oxygenase activity from Nostoc puntiforme
To Be Published
5V4T
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PROTEIN 84 WITH ALDEHYDE DEFORMYLATING OXYGENASE ACTIVITY FROM SULFOLOBUS TOKODAII (ORTHORHOMBIC FORM)
Descriptor:hypothetic aldehyde deformylating oxygenase, FE (III) ION, 1,2-ETHANEDIOL
Authors:Wilson, D.K., Mak, W.S., Siegel, J.B.
Deposit date:2017-03-10
Release date:2018-03-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Protein 84 with aldehyde deformylating oxygenase activity from Sulfolobus tokodaii (orthorhombic form)
To Be Published
1UIO
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ADENOSINE DEAMINASE (HIS 238 ALA MUTANT)
Descriptor:ADENOSINE DEAMINASE, ZINC ION, 6-HYDROXY-7,8-DIHYDRO PURINE NUCLEOSIDE
Authors:Wilson, D.K., Quiocho, F.A.
Deposit date:1996-08-30
Release date:1997-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Site-directed mutagenesis of histidine 238 in mouse adenosine deaminase: substitution of histidine 238 does not impede hydroxylate formation.
Biochemistry, 35, 1996
1UIP
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ADENOSINE DEAMINASE (HIS 238 GLU MUTANT)
Descriptor:ADENOSINE DEAMINASE, ZINC ION, PURINE RIBOSIDE
Authors:Wilson, D.K., Quiocho, F.A.
Deposit date:1996-08-30
Release date:1997-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Site-directed mutagenesis of histidine 238 in mouse adenosine deaminase: substitution of histidine 238 does not impede hydroxylate formation.
Biochemistry, 35, 1996
1FKW
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MURINE ADENOSINE DEAMINASE (D295E)
Descriptor:ADENOSINE DEAMINASE, ZINC ION, PURINE RIBOSIDE
Authors:Wilson, D.K., Quiocho, F.A.
Deposit date:1996-02-29
Release date:1996-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Probing the functional role of two conserved active site aspartates in mouse adenosine deaminase.
Biochemistry, 35, 1996
1FKX
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MURINE ADENOSINE DEAMINASE (D296A)
Descriptor:ADENOSINE DEAMINASE, ZINC ION, 6-HYDROXY-1,6-DIHYDRO PURINE NUCLEOSIDE
Authors:Wilson, D.K., Quiocho, F.A.
Deposit date:1996-02-29
Release date:1996-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Probing the functional role of two conserved active site aspartates in mouse adenosine deaminase.
Biochemistry, 35, 1996
1ABF
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SUBSTRATE SPECIFICITY AND AFFINITY OF A PROTEIN MODULATED BY BOUND WATER MOLECULES
Descriptor:L-ARABINOSE-BINDING PROTEIN, ALPHA-D-FUCOSE, BETA-D-FUCOSE
Authors:Wilson, D.K., Quiocho, F.A.
Deposit date:1992-04-23
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Substrate specificity and affinity of a protein modulated by bound water molecules.
Nature, 340, 1989
1JEZ
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THE STRUCTURE OF XYLOSE REDUCTASE, A DIMERIC ALDO-KETO REDUCTASE FROM CANDIDA TENUIS
Descriptor:XYLOSE REDUCTASE
Authors:Kavanagh, K.L., Klimacek, M., Nidetzky, B., Wilson, D.K.
Deposit date:2001-06-19
Release date:2002-07-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of apo and holo forms of xylose reductase, a dimeric aldo-keto reductase from Candida tenuis.
Biochemistry, 41, 2002
1K8C
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CRYSTAL STRUCTURE OF DIMERIC XYLOSE REDUCTASE IN COMPLEX WITH NADP(H)
Descriptor:xylose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Kavanagh, K.L., Klimacek, M., Nidetzky, B., Wilson, D.K.
Deposit date:2001-10-23
Release date:2002-07-05
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of apo and holo forms of xylose reductase, a dimeric aldo-keto reductase from Candida tenuis.
Biochemistry, 41, 2002
1LJ8
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CRYSTAL STRUCTURE OF MANNITOL DEHYDROGENASE IN COMPLEX WITH NAD
Descriptor:mannitol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Kavanagh, K.L., Klimacek, M., Nidetzky, B., Wilson, D.K.
Deposit date:2002-04-19
Release date:2002-11-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of Pseudomonas fluorescens mannitol 2-dehydrogenase binary and ternary complexes. Specificity and catalytic mechanism
J.Biol.Chem., 277, 2002
1M2W
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PSEUDOMONAS FLUORESCENS MANNITOL 2-DEHYDROGENASE TERNARY COMPLEX WITH NAD AND D-MANNITOL
Descriptor:mannitol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, D-MANNITOL
Authors:Kavanagh, K.L., Klimacek, M., Nidetzky, B., Wilson, D.K.
Deposit date:2002-06-25
Release date:2002-11-15
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Pseudomonas fluorescens Mannitol 2-Dehydrogenase Binary and Ternary Complexes. Specificity and Catalytic Mechanism
J.Biol.Chem., 277, 2002
1MI3
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1.8 ANGSTROM STRUCTURE OF XYLOSE REDUCTASE FROM CANDIDA TENUIS IN COMPLEX WITH NAD
Descriptor:xylose reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Kavanagh, K.L., Klimacek, M., Nidetzky, B., Wilson, D.K.
Deposit date:2002-08-21
Release date:2003-08-05
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of xylose reductase bound to NAD+ and the basis for single and dual co-substrate specificity in family 2 aldo-keto reductases
Biochem.J., 373, 2003
1PGU
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YEAST ACTIN INTERACTING PROTEIN 1 (AIP1), SE-MET PROTEIN, MONOCLINIC CRYSTAL FORM
Descriptor:Actin interacting protein 1, ZINC ION
Authors:Voegtli, W.C., Madrona, A.Y., Wilson, D.K.
Deposit date:2003-05-28
Release date:2003-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of Aip1p, a WD repeat protein that regulates Cofilin-mediated actin depolymerization.
J.Biol.Chem., 278, 2003
1PI6
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YEAST ACTIN INTERACTING PROTEIN 1 (AIP1), ORTHORHOMBIC CRYSTAL FORM
Descriptor:Actin interacting protein 1, ZINC ION
Authors:Voegtli, W.C., Madrona, A.Y., Wilson, D.K.
Deposit date:2003-05-29
Release date:2003-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure of Aip1p, a WD repeat protein that regulates Cofilin-mediated actin depolymerization.
J.Biol.Chem., 278, 2003