Author results

1Y69
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RRF DOMAIN I IN COMPLEX WITH THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L16, ...
Authors:Wilson, D.N., Schluenzen, F., Harms, J.M., Yoshida, T., Ohkubo, T., Albrecht, R., Buerger, J., Kobayashi, Y., Fucini, P.
Deposit date:2004-12-04
Release date:2005-03-01
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:X-ray crystallography on ribosome recycling: mechanism of binding and action of RRF on the 50S ribosomal subunit
EMBO J., 24, 2005
3DLL
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THE OXAZOLIDINONE ANTIBIOTICS PERTURB THE RIBOSOMAL PEPTIDYL-TRANSFERASE CENTER AND EFFECT TRNA POSITIONING
Descriptor:rRNA-23S ribosomal RNA, rRNA-5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Wilson, D.N., Schluenzen, F., Harms, J.M., Starosta, A.L., Connell, S.R., Fucini, P.
Deposit date:2008-06-27
Release date:2008-09-16
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
Proc.Natl.Acad.Sci.Usa, 105, 2008
3IZD
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MODEL OF THE LARGE SUBUNIT RNA EXPANSION SEGMENT ES27L-OUT BASED ON A 6.1 A CRYO-EM MAP OF SACCHAROMYCES CEREVISIAE TRANSLATING 80S RIBOSOME. 3IZD IS A SMALL PART (AN EXPANSION SEGMENT) WHICH IS IN AN ALTERNATIVE CONFORMATION TO WHAT IS IN ALREADY 3IZF.
Descriptor:rRNA expansion segment ES27L in an "out" conformation
Authors:Armache, J.-P., Jarasch, A., Anger, A.M., Villa, E., Becker, T., Bhushan, S., Jossinet, F., Habeck, M., Dindar, G., Franckenberg, S., Marquez, V., Mielke, T., Thomm, M., Berninghausen, O., Beatrix, B., Soeding, J., Westhof, E., Wilson, D.N., Beckmann, R.
Deposit date:2010-10-13
Release date:2010-12-01
Last modified:2012-05-30
Method:ELECTRON MICROSCOPY (8.6 Å)
Cite:Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 107, 2010
4V6I
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LOCALIZATION OF THE SMALL SUBUNIT RIBOSOMAL PROTEINS INTO A 6.1 A CRYO-EM MAP OF SACCHAROMYCES CEREVISIAE TRANSLATING 80S RIBOSOME
Descriptor:40S ribosomal protein RACK1 (RACK1), 40S ribosomal protein rpS0 (S2p), 40S ribosomal protein rpS3 (S3p), ...
Authors:Armache, J.-P., Jarasch, A., Anger, A.M., Villa, E., Becker, T., Bhushan, S., Jossinet, F., Habeck, M., Dindar, G., Franckenberg, S., Marquez, V., Mielke, T., Thomm, M., Berninghausen, O., Beatrix, B., Soeding, J., Westhof, E., Wilson, D.N., Beckmann, R.
Deposit date:2010-10-12
Release date:2014-07-09
Last modified:2015-03-25
Method:ELECTRON MICROSCOPY (8.8 Å)
Cite:Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 107, 2010
2D3O
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STRUCTURE OF RIBOSOME BINDING DOMAIN OF THE TRIGGER FACTOR ON THE 50S RIBOSOMAL SUBUNIT FROM D. RADIODURANS
Descriptor:23S RIBOSOMAL RNA, 50S RIBOSOMAL PROTEIN L23, 50S RIBOSOMAL PROTEIN L24, ...
Authors:Schluenzen, F., Wilson, D.N., Hansen, H.A., Tian, P., Harms, J.M., McInnes, S.J., Albrecht, R., Buerger, J., Wilbanks, S.M., Fucini, P.
Deposit date:2005-09-30
Release date:2005-12-06
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:The Binding Mode of the Trigger Factor on the Ribosome: Implications for Protein Folding and SRP Interaction
Structure, 13, 2005
2E5L
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A SNAPSHOT OF THE 30S RIBOSOMAL SUBUNIT CAPTURING MRNA VIA THE SHINE- DALGARNO INTERACTION
Descriptor:16S ribosomal RNA, 5'-R(*GP*AP*AP*AP*GP*A)-3', 30S ribosomal protein S2, ...
Authors:Kaminishi, T., Wilson, D.N., Takemoto, C., Harms, J.M., Kawazoe, M., Schluenzen, F., Hanawa-Suetsugu, K., Shirouzu, M., Fucini, P., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-12-21
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine-Dalgarno interaction
Structure, 15, 2007
2OM7
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STRUCTURAL BASIS FOR INTERACTION OF THE RIBOSOME WITH THE SWITCH REGIONS OF GTP-BOUND ELONGATION FACTORS
Descriptor:Fragment of 16S rRNA (h14), Fragment of 16S rRNA (h15), Fragment of 16S rRNA (h44), ...
Authors:Connell, S.R., Wilson, D.N., Rost, M., Schueler, M., Giesebrecht, J., Dabrowski, M., Mielke, T., Fucini, P., Spahn, C.M.T.
Deposit date:2007-01-21
Release date:2008-01-15
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors.
Mol.Cell, 25, 2007
2R1C
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COORDINATES OF THE THERMUS THERMOPHILUS RIBOSOME BINDING FACTOR A (RBFA) HOMOLOGY MODEL AS FITTED INTO THE CRYO-EM MAP OF A 30S-RBFA COMPLEX
Descriptor:Ribosome-binding factor A
Authors:Datta, P.P., Wilson, D.N., Kawazoe, M., Swami, N.K., Kaminishi, T., Sharma, M.R., Booth, T.M., Takemoto, C., Fucini, P., Yokoyama, S., Agrawal, R.K.
Deposit date:2007-08-22
Release date:2008-03-18
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (12.5 Å)
Cite:Structural aspects of RbfA action during small ribosomal subunit assembly.
Mol.Cell, 28, 2007
2R1G
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COORDINATES OF THE THERMUS THERMOPHILUS 30S COMPONENTS NEIGHBORING RBFA AS OBTAINED BY FITTING INTO THE CRYO-EM MAP OF A 30S-RBFA COMPLEX
Descriptor:16S RIBOSOMAL RNA HELIX 1, 16S RIBOSOMAL RNA HELIX 18, 16S RIBOSOMAL RNA HELIX 27, ...
Authors:Datta, P.P., Wilson, D.N., Kawazoe, M., Swami, N.K., Kaminishi, T., Sharma, M.R., Booth, T.M., Takemoto, C., Fucini, P., Yokoyama, S., Agrawal, R.K.
Deposit date:2007-08-22
Release date:2008-03-18
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (12.5 Å)
Cite:Structural aspects of RbfA action during small ribosomal subunit assembly.
Mol.Cell, 28, 2007
2ZJP
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THIOPEPTIDE ANTIBIOTIC NOSIHEPTIDE BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF DEINOCOCCUS RADIODURANS
Descriptor:50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, 50S RIBOSOMAL PROTEIN L35, ...
Authors:Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P.
Deposit date:2008-03-07
Release date:2008-06-17
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
Mol.Cell, 30, 2008
2ZJQ
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INTERACTION OF L7 WITH L11 INDUCED BY MICROCCOCIN BINDING TO THE DEINOCOCCUS RADIODURANS 50S SUBUNIT
Descriptor:ribosomal 23S RNA, ribosomal 5S RNA, 50S ribosomal protein L2, ...
Authors:Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P.
Deposit date:2008-03-08
Release date:2008-06-17
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Mol.Cell, 30, 2008
2ZJR
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REFINED NATIVE STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT (50S) FROM DEINOCOCCUS RADIODURANS
Descriptor:ribosomal 23S RNA, ribosomal 5S RNA, 50S ribosomal protein L2, ...
Authors:Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P.
Deposit date:2008-03-08
Release date:2008-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Mol.Cell, 30, 2008
3CF5
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THIOPEPTIDE ANTIBIOTIC THIOSTREPTON BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF DEINOCOCCUS RADIODURANS
Descriptor:50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, 50S RIBOSOMAL PROTEIN L35, ...
Authors:Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P.
Deposit date:2008-03-02
Release date:2008-06-17
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
Mol.Cell, 30, 2008
3DEG
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COMPLEX OF ELONGATING ESCHERICHIA COLI 70S RIBOSOME AND EF4(LEPA)-GMPPNP
Descriptor:A/L-tRNA, P-tRNA, 30S RNA helix 8, ...
Authors:Connell, S.R., Topf, M., Qin, Y., Wilson, D.N., Mielke, T., Fucini, P., Nierhaus, K.H., Spahn, C.M.T.
Deposit date:2008-06-10
Release date:2008-08-19
Last modified:2014-04-16
Method:ELECTRON MICROSCOPY (10.9 Å)
Cite:A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation
Nat.Struct.Mol.Biol., 15, 2008
3J25
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STRUCTURAL BASIS FOR TETM-MEDIATED TETRACYCLINE RESISTANCE
Descriptor:Tetracycline resistance protein tetM, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
Authors:Doenhoefer, A., Franckenberg, S., Wickles, S., Berninghausen, O., Beckmann, R., Wilson, D.N.
Deposit date:2012-08-22
Release date:2012-10-17
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Structural basis for TetM-mediated tetracycline resistance.
Proc.Natl.Acad.Sci.USA, 109, 2012
3J5L
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STRUCTURE OF THE E. COLI 50S SUBUNIT WITH ERMBL NASCENT CHAIN
Descriptor:50S ribosomal protein L32, 50S ribosomal protein L33, 50S ribosomal protein L34, ...
Authors:Arenz, S., Ramu, H., Gupta, P., Berninghausen, O., Beckmann, R., Vazquez-Laslop, N., Mankin, A.S., Wilson, D.N.
Deposit date:2013-10-23
Release date:2014-03-26
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide.
Nat Commun, 5, 2014
3J7Z
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STRUCTURE OF THE E. COLI 50S SUBUNIT WITH ERMCL NASCENT CHAIN
Descriptor:50S ribosomal protein L32, 50S ribosomal protein L33, 50S ribosomal protein L34, ...
Authors:Arenz, S., Meydan, S., Starosta, A.L., Berninghausen, O., Beckmann, R., Vazquez-Laslop, N., Wilson, D.N.
Deposit date:2014-08-27
Release date:2014-10-22
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Drug Sensing by the Ribosome Induces Translational Arrest via Active Site Perturbation.
Mol.Cell, 56, 2014
3J9W
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CRYO-EM STRUCTURE OF THE BACILLUS SUBTILIS MIFM-STALLED RIBOSOME COMPLEX
Descriptor:16S ribosomal RNA, 30S ribosomal protein uS2, 30S ribosomal protein uS3, ...
Authors:Sohmen, D., Chiba, S., Shimokawa-Chiba, N., Innis, C.A., Berninghausen, O., Beckmann, R., Ito, K., Wilson, D.N.
Deposit date:2015-03-16
Release date:2015-04-29
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the Bacillus subtilis 70S ribosome reveals the basis for species-specific stalling.
Nat Commun, 6, 2015
3J9Y
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CRYO-EM STRUCTURE OF TETRACYCLINE RESISTANCE PROTEIN TETM BOUND TO A TRANSLATING E.COLI RIBOSOME
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S4, ...
Authors:Arenz, S., Nguyen, F., Beckmann, R., Wilson, D.N.
Deposit date:2015-03-23
Release date:2015-04-15
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of the tetracycline resistance protein TetM in complex with a translating ribosome at 3.9- angstrom resolution.
Proc.Natl.Acad.Sci.USA, 112, 2015
4PSL
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CRYSTAL STRUCTURE OF PFUTHERMO-DBP-RP1 (CRYSTAL FORM I)
Descriptor:ssDNA binding protein, SULFATE ION
Authors:Gahlei, H., von Moeller, H., Eppers, D., Sohmen, D., Wilson, D.N., Loll, B., Wahl, M.C.
Deposit date:2014-03-07
Release date:2014-04-30
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Entrapment of DNA in an intersubunit tunnel system of a single-stranded DNA-binding protein.
Nucleic Acids Res., 42, 2014
4UE4
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STRUCTURAL BASIS FOR TARGETING AND ELONGATION ARREST OF BACILLUS SIGNAL RECOGNITION PARTICLE
Descriptor:6S RNA, FTSQ SIGNAL SEQUENCE, SIGNAL RECOGNITION PARTICLE PROTEIN
Authors:Beckert, B., Kedrov, A., Sohmen, D., Kempf, G., Wild, K., Sinning, I., Stahlberg, H., Wilson, D.N., Beckmann, R.
Deposit date:2014-12-15
Release date:2015-09-09
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Translational Arrest by a Prokaryotic Signal Recognition Particle is Mediated by RNA Interactions.
Nat.Struct.Mol.Biol., 22, 2015
4UE5
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STRUCTURAL BASIS FOR TARGETING AND ELONGATION ARREST OF BACILLUS SIGNAL RECOGNITION PARTICLE
Descriptor:7S RNA, SRP14, SIGNAL RECOGNITION PARTICLE SUBUNIT SRP68, ...
Authors:Beckert, B., Kedrov, A., Sohmen, D., Kempf, G., Wild, K., Sinning, I., Stahlberg, H., Wilson, D.N., Beckmann, R.
Deposit date:2014-12-15
Release date:2015-09-09
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Translational Arrest by a Prokaryotic Signal Recognition Particle is Mediated by RNA Interactions.
Nat.Struct.Mol.Biol., 22, 2015
4V5H
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E.COLI 70S RIBOSOME STALLED DURING TRANSLATION OF TNAC LEADER PEPTIDE.
Descriptor:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Seidelt, B., Innis, C.A., Wilson, D.N., Gartmann, M., Armache, J., Villa, E., Trabuco, L.G., Becker, T., Mielke, T., Schulten, K., Steitz, T.A., Beckmann, R.
Deposit date:2009-10-26
Release date:2014-07-09
Last modified:2018-04-18
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structural insight into nascent polypeptide chain-mediated translational stalling.
Science, 326, 2009
4V5M
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TRNA TRANLOCATION ON THE 70S RIBOSOME: THE PRE-TRANSLOCATIONAL TRANSLOCATION INTERMEDIATE TI(PRE)
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Ratje, A.H., Loerke, J., Mikolajka, A., Bruenner, M., Hildebrand, P.W., Starosta, A.L., Doenhoefer, A., Connell, S.R., Fucini, P., Mielke, T., Whitford, P.C., Onuchic, J.N., Yu, Y., Sanbonmatsu, K.Y., Hartmann, R.K., Penczek, P.A., Wilson, D.N., Spahn, C.M.T.
Deposit date:2010-10-01
Release date:2014-07-09
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
4V5N
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TRNA TRANSLOCATION ON THE 70S RIBOSOME: THE POST- TRANSLOCATIONAL TRANSLOCATION INTERMEDIATE TI(POST)
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Ratje, A.H., Loerke, J., Mikolajka, A., Bruenner, M., Hildebrand, P.W., Starosta, A.L., Doenhoefer, A., Connell, S.R., Fucini, P., Mielke, T., Whitford, P.C., Onuchic, J.N., Yu, Y., Sanbonmatsu, K.Y., Hartmann, R.K., Penczek, P.A., Wilson, D.N., Spahn, C.M.T.
Deposit date:2010-10-21
Release date:2014-07-09
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
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