2TMP
 
 | | N-TERMINAL DOMAIN OF TISSUE INHIBITOR OF METALLOPROTEINASE-2 (N-TIMP-2), NMR, 49 STRUCTURES | | Descriptor: | TISSUE INHIBITOR OF METALLOPROTEINASES-2 | | Authors: | Muskett, F.W, Frenkiel, T.A, Feeney, J, Freedman, R.B, Carr, M.D, Williamson, R.A. | | Deposit date: | 1998-05-26 | | Release date: | 1998-12-09 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | High resolution structure of the N-terminal domain of tissue inhibitor of metalloproteinases-2 and characterization of its interaction site with matrix metalloproteinase-3.
J.Biol.Chem., 273, 1998
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1CR9
 | | CRYSTAL STRUCTURE OF THE ANTI-PRION FAB 3F4 | | Descriptor: | FAB ANTIBODY HEAVY CHAIN, FAB ANTIBODY LIGHT CHAIN | | Authors: | Kanyo, Z.F, Pan, K.M, Williamson, R.A, Burton, D.R, Prusiner, S.B, Fletterick, R.J, Cohen, F.E. | | Deposit date: | 1999-08-14 | | Release date: | 2000-04-17 | | Last modified: | 2018-04-04 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.
J.Mol.Biol., 293, 1999
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1CU4
 | | CRYSTAL STRUCTURE OF THE ANTI-PRION FAB 3F4 IN COMPLEX WITH ITS PEPTIDE EPITOPE | | Descriptor: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, RECOGNITION PEPTIDE | | Authors: | Kanyo, Z.F, Pan, K.M, Williamson, R.A, Burton, D.R, Prusiner, S.B, Fletterick, R.J, Cohen, F.E. | | Deposit date: | 1999-08-20 | | Release date: | 2000-04-17 | | Last modified: | 2018-04-04 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.
J.Mol.Biol., 293, 1999
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1NYO
 | | Solution structure of the antigenic TB protein MPT70/MPB70 | | Descriptor: | Immunogenic protein MPT70 | | Authors: | Bloemink, M.J, Dentten, E, Hewinson, R.G, Williamson, R.A, Carr, M.D, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2003-02-13 | | Release date: | 2003-08-19 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the Mycobacterium tuberculosis complex protein MPB70: from tuberculosis pathogenesis to inherited human corneal desease
J.Biol.Chem., 278, 2003
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2K8V
 | | Solution structure of Oxidised ERp18 | | Descriptor: | Thioredoxin domain-containing protein 12 | | Authors: | Rowe, M.L, Alanen, H.I, Ruddock, L.W, Kelly, G, Schmidt, J.M, Williamson, R.A, Howard, M.J. | | Deposit date: | 2008-09-25 | | Release date: | 2009-06-02 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | Solution structure and dynamics of ERp18, a small endoplasmic reticulum resident oxidoreductase .
Biochemistry, 48, 2009
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1WA8
 | | Solution Structure of the CFP-10.ESAT-6 Complex. Major Virulence Determinants of Pathogenic Mycobacteria | | Descriptor: | 6 KDA EARLY SECRETORY ANTIGENIC TARGET (ESAT-6), ESAT-6 LIKE PROTEIN ESXB | | Authors: | Renshaw, P.S, Lightbody, K.L, Veverka, V, Muskett, F.W, Kelly, G, Frenkiel, T.A, Gordon, S.V, Hewinson, R.G, Burke, B, Norman, J, Williamson, R.A, Carr, M.D, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2004-10-25 | | Release date: | 2005-06-27 | | Last modified: | 2019-08-21 | | Method: | SOLUTION NMR | | Cite: | Structure and Function of the Complex Formed by the Tuberculosis Virulence Factors Cfp-10 and Esat-6
Embo J., 24, 2005
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2L4C
 | | Solution Structure of the b domain of Human ERp27 | | Descriptor: | Endoplasmic reticulum resident protein 27 | | Authors: | Amin, N.T, Wallis, K, Rowe, M.L, Kelly, G, Frenkiel, T.A, Williamson, R.A, Howard, M.J, Freedman, R.B. | | Deposit date: | 2010-10-03 | | Release date: | 2010-11-10 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure and dynamics of the b domain of human ERp27
To be Published
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3BJ5
 | | Alternative conformations of the x region of human protein disulphide-isomerase modulate exposure of the substrate binding b' domain | | Descriptor: | Protein disulfide-isomerase, SULFATE ION | | Authors: | Ruddock, L.W, Nguyen, V.D, Wierenga, R.K, Haapalainen, A.M. | | Deposit date: | 2007-12-03 | | Release date: | 2008-09-30 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Alternative conformations of the x region of human protein disulphide-isomerase modulate exposure of the substrate binding b' domain
J.Mol.Biol., 383, 2008
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4AWI
 | | Human Jnk1alpha kinase with 4-phenyl-7-azaindole IKK2 inhibitor. | | Descriptor: | MITOGEN-ACTIVATED PROTEIN KINASE 8, N-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-4-[2-(1-methylethyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]benzenesulfonamide, SULFATE ION | | Authors: | Chung, C, Vicentini, G, Liddle, J, Bamborough, P. | | Deposit date: | 2012-06-03 | | Release date: | 2013-05-01 | | Last modified: | 2014-07-30 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | 4-Phenyl-7-Azaindoles as Potent, Selective and Bioavailable Ikk2 Inhibitors Demonstrating Good in Vivo Efficacy.
Bioorg.Med.Chem.Lett., 22, 2012
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2HH0
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6BLI
 | | RSV G peptide bound to Fab CB002.5 | | Descriptor: | CB002.5 Fab Heavy Chain, CB002.5 Fab Light Chain, Major surface glycoprotein G | | Authors: | Jones, H.G, McLellan, J.S, Langedijk, J.P. | | Deposit date: | 2017-11-10 | | Release date: | 2018-02-28 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.
PLoS Pathog., 14, 2018
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6BLH
 | | RSV G central conserved region bound to Fab CB017.5 | | Descriptor: | 1,2-ETHANEDIOL, Fab CB017.5 heavy chain, Fab CB017.5 light chain, ... | | Authors: | Jones, H.G, McLellan, J.S, Langedijk, J.P. | | Deposit date: | 2017-11-10 | | Release date: | 2018-02-28 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.
PLoS Pathog., 14, 2018
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