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6BIT
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BU of 6bit by Molmil
SIRPalpha antibody complex
Descriptor: KWAR23 Fab heavy chain, KWAR23 Fab light chain, Tyrosine-protein phosphatase non-receptor type substrate 1
Authors:Ring, N.G, Herndler-Brandstetter, D, Weiskopf, K, Shan, L, Volkmer, J.P, George, B.M, Lietzenmayer, M, McKenna, K.M, Naik, T.J, McCarty, A, Zheng, Y, Ring, A.M, Flavell, R.A, Weissman, I.L.
Deposit date:2017-11-03
Release date:2017-12-06
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.191 Å)
Cite:Anti-SIRP alpha antibody immunotherapy enhances neutrophil and macrophage antitumor activity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5IWL
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BU of 5iwl by Molmil
CD47-diabody complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5F9 diabody, Leukocyte surface antigen CD47, ...
Authors:Di, W, Jude, K.M, Garcia, K.C.
Deposit date:2016-03-22
Release date:2016-06-29
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer.
J.Clin.Invest., 126, 2016
4KJY
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BU of 4kjy by Molmil
Complex of high-affinity SIRP alpha variant FD6 with CD47
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, High-affinity SIRPa variant FD6, Leukocyte surface antigen CD47, ...
Authors:Ring, A.M, Ozkan, E, Ho, C.C.M, Garcia, K.C.
Deposit date:2013-05-04
Release date:2013-06-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Engineered SIRP alpha variants as immunotherapeutic adjuvants to anticancer antibodies.
Science, 341, 2013
4Y5Y
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BU of 4y5y by Molmil
Diabody 330 complex with EpoR
Descriptor: Erythropoietin receptor, GLYCEROL, diabody 330 VH domain, ...
Authors:Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C.
Deposit date:2015-02-12
Release date:2015-03-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.
Cell, 160, 2015
4Y5X
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BU of 4y5x by Molmil
Diabody 305 complex with EpoR
Descriptor: CITRATE ANION, DI(HYDROXYETHYL)ETHER, Erythropoietin receptor, ...
Authors:Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C.
Deposit date:2015-02-12
Release date:2015-03-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.
Cell, 160, 2015
4Y5V
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BU of 4y5v by Molmil
Diabody 305 complex with EpoR
Descriptor: DI(HYDROXYETHYL)ETHER, Diabody 305 VL domain, Erythropoietin receptor, ...
Authors:Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C.
Deposit date:2015-02-12
Release date:2015-04-29
Method:X-RAY DIFFRACTION (2.604 Å)
Cite:Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.
Cell, 160, 2015

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PDB entries from 2024-03-27

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