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8T4R
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BU of 8t4r by Molmil
RAG2-PHD finger in complex with H3K4tBuNle peptide
Descriptor: H3 histone peptide, V(D)J recombination-activating protein 2, ZINC ION
Authors:Kean, K.M, Travis, C.R, Waters, M.L.
Deposit date:2023-06-09
Release date:2024-02-14
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Trimethyllysine Reader Proteins Exhibit Widespread Charge-Agnostic Binding via Different Mechanisms to Cationic and Neutral Ligands.
J.Am.Chem.Soc., 146, 2024
6MHA
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BU of 6mha by Molmil
dHP1 Chromodomain Y24W variant bound to histone H3 peptide containing trimethyllysine
Descriptor: Heterochromatin protein 1, histone H3 peptide containing trimethyllysine, H3K9me3
Authors:Brustad, E.M, Krone, M.W, Albanese, K.I, Waters, M.L.
Deposit date:2018-09-17
Release date:2019-09-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.497 Å)
Cite:Thermodynamic consequences of Tyr to Trp mutations in the cation-pi-mediated binding of trimethyllysine by the HP1 chromodomain
Chem Sci, 11, 2020
6ASZ
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BU of 6asz by Molmil
Chromodomain HP1 with Y24F mutation bound to histone H3 peptide containing trimethyl lysine
Descriptor: Heterochromatin protein 1, trimethyl lysine histone H3 tail peptide
Authors:Brustad, E.M, Baril, S.A, Waters, M.L.
Deposit date:2017-08-27
Release date:2017-12-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.518 Å)
Cite:Investigation of Trimethyllysine Binding by the HP1 Chromodomain via Unnatural Amino Acid Mutagenesis.
J. Am. Chem. Soc., 139, 2017
6AT0
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BU of 6at0 by Molmil
Chromodomain HP1 with a p-nitro-L-phenylalanine mutation at position 24 bound to histone H3 peptide containing trimethyl lysine
Descriptor: Heterochromatin protein 1, trimethyl lysine histone H3 tail peptide
Authors:Brustad, E.M, Baril, S.A, Waters, M.L.
Deposit date:2017-08-27
Release date:2017-12-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.285 Å)
Cite:Investigation of Trimethyllysine Binding by the HP1 Chromodomain via Unnatural Amino Acid Mutagenesis.
J. Am. Chem. Soc., 139, 2017
5K1X
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BU of 5k1x by Molmil
Catalytic domain of polyspecific pyrrolysyl-tRNA synthetase mutant Y306A/N346A/C348A/Y384F in complex with AMPPNP
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Weber, A.
Deposit date:2016-05-18
Release date:2016-10-19
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Genetically encoded fluorophenylalanines enable insights into the recognition of lysine trimethylation by an epigenetic reader.
Chem.Commun.(Camb.), 52, 2016
5K1P
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BU of 5k1p by Molmil
Catalytic domain of polyspecific pyrrolysyl-tRNA synthetase mutant N346A/C348A in complex with AMPPNP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Pyrrolysine--tRNA ligase
Authors:Weber, A.
Deposit date:2016-05-18
Release date:2016-10-19
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Genetically encoded fluorophenylalanines enable insights into the recognition of lysine trimethylation by an epigenetic reader.
Chem.Commun.(Camb.), 52, 2016

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PDB entries from 2024-04-17

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