Author results

3DBQ
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CRYSTAL STRUCTURE OF TTK KINASE DOMAIN
Descriptor:Dual specificity protein kinase TTK
Authors:Wang, W., Yang, Y.T., Gao, Y.F., Zhu, S.C., Wang, F., Old, W., Xu, Q.B., Resing, K., Ahn, N., Lei, M., Liu, X.D.
Deposit date:2008-06-02
Release date:2009-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and Mechanistic Insights into Mps1 Kinase Activation
J.CELL.MOL.MED., 13, 2008
3VPV
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA TSI2
Descriptor:Tse2 specific immunity protein 2
Authors:Wang, W., Ding, J., Wang, D.C.
Deposit date:2012-03-13
Release date:2012-03-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Pseudomonas aeruginosa Tsi2
To be Published
4EB3
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CRYSTAL STRUCTURE OF ISPH IN COMPLEX WITH ISO-HMBPP
Descriptor:4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER, 3-(hydroxymethyl)but-3-en-1-yl trihydrogen diphosphate
Authors:Wang, W., Wang, K., Span, I., Bacher, A., Groll, M., Oldfield, E.
Deposit date:2012-03-23
Release date:2013-02-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Are free radicals involved in IspH catalysis? An EPR and crystallographic investigation.
J.Am.Chem.Soc., 134, 2012
5W4U
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POL II ELONGATION COMPLEX WITH AN N6-METHYLADENINE-CONTAINING TEMPLATE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, W., Wang, D.
Deposit date:2017-06-13
Release date:2018-06-20
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Epigenetic DNA Modification N6-Methyladenine Causes Site-Specific RNA Polymerase II Transcriptional Pausing.
J.Am.Chem.Soc., 139, 2017
5W51
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POL II ELONGATION COMPLEX WITH AN N6-METHYLADENINE-CONTAINING TEMPLATE AND A MATCHED UMPNPP
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, W., Wang, D.
Deposit date:2017-06-13
Release date:2018-06-20
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (3.404 Å)
Cite:Epigenetic DNA Modification N6-Methyladenine Causes Site-Specific RNA Polymerase II Transcriptional Pausing.
J.Am.Chem.Soc., 139, 2017
5XET
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS METHIONYL-TRNA SYNTHETASE BOUND BY METHIONYL-ADENYLATE (MET-AMP)
Descriptor:Methionine--tRNA ligase, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] (2S)-2-azanyl-4-methylsulfanyl-butanoate, 1,2-ETHANEDIOL, ...
Authors:Wang, W., Qin, B., Wojdyla, J.A., Wang, M., Gao, X., Cui, S.
Deposit date:2017-04-06
Release date:2018-07-11
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural characterization of free-state and product-stateMycobacterium tuberculosismethionyl-tRNA synthetase reveals an induced-fit ligand-recognition mechanism.
IUCrJ, 5, 2018
5XGQ
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CRYSTAL STRUCTURE OF APO FORM (FREE-STATE) MYCOBACTERIUM TUBERCULOSIS METHIONYL-TRNA SYNTHETASE
Descriptor:Methionine-tRNA ligase
Authors:Wang, W., Wang, M., Wojdyla, J.A., Cui, S.
Deposit date:2017-04-15
Release date:2018-07-11
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Structural characterization of free-state and product-stateMycobacterium tuberculosismethionyl-tRNA synthetase reveals an induced-fit ligand-recognition mechanism
IUCrJ, 5, 2018
5Z1Q
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CRYSTAL STRUCTURES OF THE TRIMERIC N-TERMINAL DOMAIN OF CILIATE EUPLOTES OCTOCARINATUS CENTRIN
Descriptor:Centrin protein, CALCIUM ION, CHLORIDE ION
Authors:Wang, W., Zhao, Y., Yang, B., Wang, H.
Deposit date:2017-12-27
Release date:2018-04-25
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the trimeric N-terminal domain of ciliate Euplotes octocarinatus centrin binding with calcium ions
Protein Sci., 27, 2018
6BLO
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POL II ELONGATION COMPLEX WITH AN ABASIC LESION AT I+1 POSITION
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, W., Wang, D.
Deposit date:2017-11-10
Release date:2018-02-28
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (3.401 Å)
Cite:Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BLP
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POL II ELONGATION COMPLEX WITH AN ABASIC LESION AT I+1 POSITION, SOAKING AMPCPP
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, W., Wang, D.
Deposit date:2017-11-11
Release date:2018-02-28
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (3.203 Å)
Cite:Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BM2
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POL II ELONGATION COMPLEX WITH AN ABASIC LESION AT I-1 POSITION
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, W., Wang, D.
Deposit date:2017-11-13
Release date:2018-02-28
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (3.403 Å)
Cite:Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BM4
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POL II ELONGATION COMPLEX WITH AN ABASIC LESION AT I-1 POSITION,SOAKING UMPNPP
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, W., Wang, D.
Deposit date:2017-11-13
Release date:2018-02-28
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.951 Å)
Cite:Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BQF
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POL II ELONGATION COMPLEX WITH 'DT-AP' AT I+1, I-1 POSITION
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, W., Wang, D.
Deposit date:2017-11-27
Release date:2018-02-28
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1GSO
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GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE (GAR-SYN) FROM E. COLI.
Descriptor:PROTEIN (GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE)
Authors:Wang, W., Kappock, T.J., Stubbe, J., Ealick, S.E.
Deposit date:1998-09-08
Release date:1998-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-ray crystal structure of glycinamide ribonucleotide synthetase from Escherichia coli.
Biochemistry, 37, 1998
4DQI
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TERNARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT, DNA DUPLEX, AND DCTP (PAIRED WITH DG OF TEMPLATE)
Descriptor:DNA polymerase I, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*C*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ...
Authors:Wang, W., Beese, L.S.
Deposit date:2012-02-15
Release date:2012-06-06
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
4DQP
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TERNARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT, DNA DUPLEX, AND DDCTP (PAIRED WITH DG OF TEMPLATE)
Descriptor:DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*C*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ...
Authors:Wang, W., Beese, L.S.
Deposit date:2012-02-16
Release date:2012-06-06
Last modified:2012-11-21
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
4DQQ
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TERNARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT E658A, DNA DUPLEX, AND RCTP (PAIRED WITH DG OF TEMPLATE) IN PRESENCE OF MG2+
Descriptor:DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ...
Authors:Wang, W., Beese, L.S.
Deposit date:2012-02-16
Release date:2012-06-06
Last modified:2012-11-21
Method:X-RAY DIFFRACTION (1.595 Å)
Cite:Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
4DQR
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TERNARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT E658A, DNA DUPLEX, AND RCTP (PAIRED WITH DG OF TEMPLATE) IN PRESENCE OF MN2+
Descriptor:DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ...
Authors:Wang, W., Beese, L.S.
Deposit date:2012-02-16
Release date:2012-06-06
Last modified:2012-11-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
4DQS
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BINARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT AND DUPLEX DNA WITH RC IN PRIMER TERMINUS PAIRED WITH DG OF TEMPLATE
Descriptor:DNA polymerase, DNA/RNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-R(P*C)-3'), DNA (5'-D(*GP*A*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ...
Authors:Wang, W., Beese, L.S.
Deposit date:2012-02-16
Release date:2012-06-06
Last modified:2012-11-21
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
4DS4
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TERNARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT, DNA DUPLEX, AND RCTP IN PRESENCE OF MN2+
Descriptor:DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ...
Authors:Wang, W., Beese, L.S.
Deposit date:2012-02-17
Release date:2012-06-06
Last modified:2012-11-21
Method:X-RAY DIFFRACTION (1.681 Å)
Cite:Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
4DS5
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TERNARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT, DNA DUPLEX, AND RCTP IN PRESENCE OF MG2+
Descriptor:DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*C)-3'), DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ...
Authors:Wang, W., Beese, L.S.
Deposit date:2012-02-17
Release date:2012-06-06
Last modified:2012-11-21
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
4DSE
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TERNARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT F710Y, DNA DUPLEX, AND RCTP (PAIRED WITH DG OF TEMPLATE) IN PRESENCE OF MG2+
Descriptor:DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ...
Authors:Wang, W., Beese, L.S.
Deposit date:2012-02-18
Release date:2012-06-06
Last modified:2012-11-21
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
4DSF
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TERNARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT F710Y, DNA DUPLEX, AND RCTP (PAIRED WITH DG OF TEMPLATE) IN PRESENCE OF MN2+
Descriptor:DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ...
Authors:Wang, W., Beese, L.S.
Deposit date:2012-02-18
Release date:2012-06-06
Last modified:2012-11-21
Method:X-RAY DIFFRACTION (1.661 Å)
Cite:Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
4E0D
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BINARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT E658A AND DUPLEX DNA
Descriptor:DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ...
Authors:Wang, W., Beese, L.S.
Deposit date:2012-03-02
Release date:2012-06-06
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
4EZ6
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BACILLUS DNA POLYMERASE I LARGE FRAGMENT COMPLEX 1
Descriptor:DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DDG))-3'), DNA (5'-D(*CP*AP*TP*GP*CP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ...
Authors:Wang, W., Beese, L.S.
Deposit date:2012-05-02
Release date:2013-07-24
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structures of a High-fidelity DNA Polymerase
to be published