Author results

5HXK
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STRUCTURE OF TTHA1265
Descriptor:Zinc-dependent peptidase
Authors:Wang, W.W., Ran, T.T., Xu, D.Q., Wang, M.T.
Deposit date:2016-01-30
Release date:2017-02-01
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of TTHA1264-1265 complex
To Be Published
5V54
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CRYSTAL STRUCTURE OF 5-HT1B RECEPTOR IN COMPLEX WITH METHIOTHEPIN
Descriptor:5-hydroxytryptamine receptor 1B,OB-1 fused 5-HT1b receptor,5-hydroxytryptamine receptor 1B, 1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine
Authors:Yin, W.C., Zhou, X.E., Yang, D., de Waal, P., Wang, M.T., Dai, A., Cai, X., Huang, C.Y., Liu, P., Yin, Y., Liu, B., Caffrey, M., Melcher, K., Xu, Y., Wang, M.W., Xu, H.E., Jiang, Y.
Deposit date:2017-03-13
Release date:2018-02-07
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:A common antagonistic mechanism for class A GPCRs revealed by the structure of the human 5-HT1B serotonin receptor bound to an antagonist
Cell Discov, 2018
5GQ1
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CRYSTAL STRUCTURE OF 2C HELICASE FROM ENTEROVIRUS 71 (EV71)
Descriptor:Genome polyprotein, ZINC ION, PHOSPHATE ION
Authors:Guan, H.X., Tian, J., Qin, B., Wojdyla, J., Wang, M.T., Cui, S.
Deposit date:2016-08-05
Release date:2017-05-17
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (2.493 Å)
Cite:Crystal structure of 2C helicase from enterovirus 71
SCI ADV, 3, 2017
5GRB
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CRYSTAL STRUCTURE OF 2C HELICASE FROM ENTEROVIRUS 71 (EV71) BOUND WITH ATPGAMMAS
Descriptor:EV71 2C ATPase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ZINC ION
Authors:Guan, H.X., Tian, J., Qin, B., Wojdyla, J., Wang, M.T., Cui, S.
Deposit date:2016-08-09
Release date:2017-05-17
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:Crystal structure of 2C helicase from enterovirus 71
SCI ADV, 3, 2017
3STQ
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HYPOTHETICAL PROTEIN PA2703 PSEUDOMONAS AERUGINOSA PAO1
Descriptor:Putative uncharacterized protein
Authors:Zou, T.T., Wang, M.T., Jin, Q., Cui, S.
Deposit date:2011-07-11
Release date:2012-02-08
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.284 Å)
Cite:Crystal structure of Pseudomonas aeruginosa Tsi2 reveals a stably folded superhelical antitoxin
J.Mol.Biol., 417, 2012
3VGY
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STRUCTURE OF HIV-1 GP41 NHR/FUSION INHIBITOR COMPLEX P321
Descriptor:Envelope glycoprotein gp160, CP32M, SULFATE ION
Authors:Yao, X., Waltersperger, S., Wang, M.T., Cui, S.
Deposit date:2011-08-22
Release date:2012-06-13
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.034 Å)
Cite:Structural basis of potent and broad HIV-1 fusion inhibitor CP32M
J.Biol.Chem., 287, 2012
3VH7
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STRUCTURE OF HIV-1 GP41 NHR/FUSION INHIBITOR COMPLEX P21
Descriptor:Envelope glycoprotein gp160, CP32M, MAGNESIUM ION
Authors:Yao, X., Waltersperger, S., Wang, M.T., Cui, S.
Deposit date:2011-08-23
Release date:2012-06-13
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.019 Å)
Cite:Structural basis of potent and broad HIV-1 fusion inhibitor CP32M
J.Biol.Chem., 287, 2012
3VU5
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SHORT PEPTIDE HIV ENTRY INHIBITOR SC22EK
Descriptor:Transmembrane protein gp41, SC22, SULFATE ION, ...
Authors:Yao, X., Chong, H.H., Waltersperger, S., Wang, M.T., He, Y.X., Cui, S.
Deposit date:2012-06-19
Release date:2012-12-19
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (2.087 Å)
Cite:Short-peptide fusion inhibitors with high potency against wild-type and enfuvirtide-resistant HIV-1
Faseb J., 27, 2013
3VU6
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SHORT PEPTIDE HIV ENTRY INHIBITOR MT-SC22EK WITH A M-T HOOK
Descriptor:Transmembrane protein gp41, MTSC22, SULFATE ION
Authors:Yao, X., Chong, H.H., Waltersperger, S., Wang, M.T., He, Y.X., Cui, S.
Deposit date:2012-06-19
Release date:2012-12-19
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (2.324 Å)
Cite:Short-peptide fusion inhibitors with high potency against wild-type and enfuvirtide-resistant HIV-1
Faseb J., 27, 2013
3VWB
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CRYSTAL STRUCTURE OF VIRB CORE DOMAIN (SE-MET DERIVATIVE) COMPLEXED WITH THE CIS-ACTING SITE (5-BRU MODIFICATIONS) UPSTREAM ICSB PROMOTER
Descriptor:Virulence regulon transcriptional activator virB, DNA (26-MER)
Authors:Gao, X.P., Waltersperger, S., Wang, M.T., Cui, S.
Deposit date:2012-08-21
Release date:2013-08-21
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.416 Å)
Cite:Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
Nucleic Acids Res., 41, 2013
3W19
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POTENT HIV FUSION INHIBITOR CP32M-2
Descriptor:Transmembrane protein gp41, fusion inhibitor CP32M-2
Authors:Yao, X., Waltersperger, S., Wang, M.T., Cui, S.
Deposit date:2012-11-13
Release date:2013-12-11
Method:X-RAY DIFFRACTION (1.278 Å)
Cite:Optimization of novel anti-HIV fusion inhibitor
To be Published
3W2A
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CRYSTAL STRUCTURE OF VIRB CORE DOMAIN COMPLEXED WITH THE CIS-ACTING SITE UPSTREAM ICSP PROMOTER
Descriptor:Virulence regulon transcriptional activator VirB, DNA (31-mer)
Authors:Gao, X.P., Waltersperger, S., Wang, M.T., Cui, S.
Deposit date:2012-11-27
Release date:2013-09-04
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.775 Å)
Cite:Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
Nucleic Acids Res., 41, 2013
3W3C
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CRYSTAL STRUCTURE OF VIRB CORE DOMAIN COMPLEXED WITH THE CIS-ACTING SITE UPSTREAM ICSB PROMOTER
Descriptor:Virulence regulon transcriptional activator VirB, DNA (26-MER)
Authors:Gao, X.P., Waltersperger, S., Wang, M.T., Cui, S.
Deposit date:2012-12-19
Release date:2013-09-04
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.431 Å)
Cite:Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
Nucleic Acids Res., 41, 2013
4I2L
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NEW HIV ENTRY INHIBITOR MTSFT/T23 COMPLEX
Descriptor:GP41, inhibitor MTSFT
Authors:Yao, X., Chong, H.H., Waltersperger, S., Wang, M.T., He, Y.X., Cui, S.
Deposit date:2012-11-22
Release date:2014-01-22
Method:X-RAY DIFFRACTION (1.426 Å)
Cite:Potent antiviral activity of the novel HIV entry inhibitor MTSFT
To be Published
3J9B
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ELECTRON CRYO-MICROSCOPY OF AN RNA POLYMERASE
Descriptor:Polymerase, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ...
Authors:Chang, S.H., Sun, D.P., Liang, H.H., Wang, J., Li, J., Guo, L., Wang, X.L., Guan, C.C., Boruah, B.M., Yuan, L.M., Feng, F., Yang, M.R., Wojdyla, J., Wang, J.W., Wang, M.T., Wang, H.W., Liu, Y.F.
Deposit date:2014-12-16
Release date:2015-02-18
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Cryo-EM Structure of Influenza Virus RNA Polymerase Complex at 4.3 angstrom Resolution.
Mol.Cell, 2015
4DBF
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CRYSTAL STRUCTURES OF CG1458
Descriptor:2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE, MAGNESIUM ION
Authors:Ran, T.T., Xu, D.Q., Wang, W.W., Gao, Y.Y., Wang, M.T.
Deposit date:2012-01-15
Release date:2012-11-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of Cg1458 reveal a catalytic lid domain and a common catalytic mechanism for FAH family.
Biochem.J., 449, 2013
3VIE
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HIV-GP41 FUSION INHIBITOR SIFUVIRTIDE
Descriptor:Envelope glycoprotein gp160, Sifuvirtide
Authors:Yao, X., Waltersperger, S., Wang, M.T., Cui, S.
Deposit date:2011-09-29
Release date:2012-01-18
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Broad antiviral activity and crystal structure of HIV-1 fusion inhibitor sifuvirtide
J.Biol.Chem., 287, 2012