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6JFH
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THE ASYMMETRIC-RECONSTRUCTED CRYO-EM STRUCTURE OF ZIKA VIRUS-FABZK2B10 COMPLEX
Descriptor:ZIKV structural E protein, strutural protein M, FabZK2B10 heavy chain, ...
Authors:Wang, L., Wang, R.K., Wang, L., Ben, H.J., Yu, L., Gao, F., Shi, X.L., Yin, C.B., Zhang, F.C., Xiang, Y., Zhang, L.Q.
Deposit date:2019-02-08
Release date:2019-04-10
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Structural Basis for Neutralization and Protection by a Zika Virus-Specific Human Antibody.
Cell Rep, 26, 2019
6JFI
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THE SYMMETRIC-RECONSTRUCTED CRYO-EM STRUCTURE OF ZIKA VIRUS-FABZK2B10 COMPLEX
Descriptor:ZIKV structural protein E, strutural protein M, FabZK2B10 heavy chain, ...
Authors:Wang, L., Wang, R.K., Wang, L., Ben, H.J., Yu, L., Gao, F., Shi, X.L., Yin, C.B., Zhang, F.C., Xiang, Y., Zhang, L.Q.
Deposit date:2019-02-08
Release date:2019-04-10
Method:ELECTRON MICROSCOPY (11 Å)
Cite:Structural Basis for Neutralization and Protection by a Zika Virus-Specific Human Antibody.
Cell Rep, 26, 2019
3Q47
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CRYSTAL STRUCTURE OF TPR DOMAIN OF CHIP COMPLEXED WITH PSEUDOPHOSPHORYLATED SMAD1 PEPTIDE
Descriptor:STIP1 homology and U box-containing protein 1, Smad1 peptide
Authors:Wang, L., Chen, L., Wu, J.W.
Deposit date:2010-12-23
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.705 Å)
Cite:Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
3Q49
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CRYSTAL STRUCTURE OF THE TPR DOMAIN OF CHIP COMPLEXED WITH HSP70-C PEPTIDE
Descriptor:STIP1 homology and U box-containing protein 1, Hsp70-C peptide
Authors:Wang, L., Chen, L., Wu, J.W.
Deposit date:2010-12-23
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.543 Å)
Cite:Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
3Q4A
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CRYSTAL STRUCTURE OF THE TPR DOMAIN OF CHIP COMPLEXED WITH PHOSPHORYLATED SMAD1 PEPTIDE
Descriptor:STIP1 homology and U box-containing protein 1, Smad1 peptide
Authors:Wang, L., Chen, L., Wu, J.W.
Deposit date:2010-12-23
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.542 Å)
Cite:Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
4Y52
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CRYSTAL STRUCTURE OF 5-CARBOXYCYTOSINE RECOGNITION BY RNA POLYMERASE II DURING TRANSCRIPTION ELONGATION.
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, L., Chong, J., Wang, D.
Deposit date:2015-02-11
Release date:2015-07-15
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.
Nature, 523, 2015
4Y7N
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THE STRUCTURE INSIGHT INTO 5-CARBOXYCYTOSINE RECOGNITION BY RNA POLYMERASE II DURING TRANSCRIPTION ELONGATION.
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2,DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, L., Chong, J., Wang, D.
Deposit date:2015-02-15
Release date:2015-07-15
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.
Nature, 523, 2015
3TJU
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CRYSTAL STRUCTURE OF HUMAN GRANZYME H WITH AN INHIBITOR
Descriptor:Granzyme H, Ac-PTSY-CMK inhibitor, SULFATE ION
Authors:Wang, L., Zhang, K., Wu, L., Tong, L., Sun, F., Fan, Z.
Deposit date:2011-08-25
Release date:2011-12-28
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif
J.Immunol., 188, 2012
3TJV
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CRYSTAL STRUCTURE OF HUMAN GRANZYME H WITH A PEPTIDYL SUBSTRATE
Descriptor:Granzyme H, PTSYAGDDSG, SULFATE ION
Authors:Wang, L., Zhang, K., Wu, L., Tong, L., Sun, F., Fan, Z.
Deposit date:2011-08-25
Release date:2011-12-28
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif
J.Immunol., 188, 2012
3TK9
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CRYSTAL STRUCTURE OF HUMAN GRANZYME H
Descriptor:Granzyme H, SULFATE ION
Authors:Wang, L., Zhang, K., Wu, L., Tong, L., Sun, F., Fan, Z.
Deposit date:2011-08-25
Release date:2011-12-28
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif
J.Immunol., 188, 2012
4GA7
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CRYSTAL STRUCTURE OF HUMAN SERPINB1 MUTANT
Descriptor:Leukocyte elastase inhibitor
Authors:Wang, L., Li, Q., Wu, L., Zhang, K., Tong, L., Sun, F., Fan, Z.
Deposit date:2012-07-25
Release date:2013-01-16
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Identification of SERPINB1 as a physiological inhibitor of human granzyme H
J.Immunol., 190, 2013
4GAW
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CRYSTAL STRUCTURE OF ACTIVE HUMAN GRANZYME H
Descriptor:Granzyme H, SULFATE ION, CHLORIDE ION
Authors:Wang, L., Li, Q., Wu, L., Zhang, K., Tong, L., Sun, F., Fan, Z.
Deposit date:2012-07-25
Release date:2013-01-16
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Identification of SERPINB1 as a physiological inhibitor of human granzyme H
J.Immunol., 190, 2013
2JRT
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NMR SOLUTION STRUCTURE OF THE PROTEIN CODED BY GENE RHOS4_12090 OF RHODOBACTER SPHAEROIDES. NORTHEAST STRUCTURAL GENOMICS TARGET RHR5
Descriptor:Uncharacterized protein
Authors:Wang, L., Chen, C., Nwosu, C., Cunningham, K., Owens, L., Ma, L., Xiao, R., Liu, J., Baran, M.C., Swapna, G., Acton, T.B., Rost, B., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2007-06-28
Release date:2007-08-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR solution structure of the protein coded by gene RHOS4_12090 of Rhodobacter sphaeroides.
To be Published
4JR4
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CRYSTAL STRUCTURE OF MTB DSBA (OXIDIZED)
Descriptor:Possible conserved membrane or secreted protein, SULFATE ION
Authors:Wang, L.
Deposit date:2013-03-21
Release date:2013-07-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.498 Å)
Cite:Structure analysis of the extracellular domain reveals disulfide bond forming-protein properties of Mycobacterium tuberculosis Rv2969c.
Protein Cell, 4, 2013
4JR6
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CRYSTAL STRUCTURE OF DSBA FROM MYCOBACTERIUM TUBERCULOSIS (REDUCED)
Descriptor:Possible conserved membrane or secreted protein, SULFATE ION
Authors:Wang, L.
Deposit date:2013-03-21
Release date:2013-07-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:Structure analysis of the extracellular domain reveals disulfide bond forming-protein properties of Mycobacterium tuberculosis Rv2969c.
Protein Cell, 4, 2013
4NSC
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CRYSTAL STRUCTURE OF CBARA1 IN THE APO-FORM
Descriptor:Calcium uptake protein 1, mitochondrial
Authors:Wang, L., Yang, X., Li, S., Shen, Y.
Deposit date:2013-11-28
Release date:2014-02-26
Last modified:2014-04-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake.
Embo J., 33, 2014
4NSD
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CRYSTAL STRUCTURE OF CBARA1 IN THE CA2+ BINDING FORM
Descriptor:Calcium uptake protein 1, mitochondrial, CALCIUM ION, ...
Authors:Wang, L., Yang, X., Li, S., Shen, Y.
Deposit date:2013-11-28
Release date:2014-02-26
Last modified:2014-04-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake.
Embo J., 33, 2014
5YR2
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STRUCTURE OF CPGFP66BPA
Descriptor:Green fluorescent protein
Authors:Wang, L., Kang, F., Wang, J.
Deposit date:2017-11-08
Release date:2019-01-30
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Structure of cpGFP66BPA
To Be Published
1BLR
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NMR SOLUTION STRUCTURE OF HUMAN CELLULAR RETINOIC ACID BINDING PROTEIN-TYPE II, 22 STRUCTURES
Descriptor:CELLULAR RETINOIC ACID BINDING PROTEIN-TYPE II
Authors:Wang, L., Li, Y., Abilddard, F., Yan, H., Markely, J.
Deposit date:1998-07-20
Release date:1999-01-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR solution structure of type II human cellular retinoic acid binding protein: implications for ligand binding.
Biochemistry, 37, 1998
1MLW
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CRYSTAL STRUCTURE OF HUMAN TRYPTOPHAN HYDROXYLASE WITH BOUND 7,8-DIHYDRO-L-BIOPTERIN COFACTOR AND FE(III)
Descriptor:Tryptophan 5-monooxygenase, FE (III) ION, 7,8-DIHYDROBIOPTERIN
Authors:Wang, L., Erlandsen, H., Haavik, J., Knappskog, P.M., Stevens, R.C.
Deposit date:2002-08-31
Release date:2002-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Three-dimensional structure of human tryptophan hydroxylase and its implications for the biosynthesis of the neurotransmitters serotonin and melatonin
Biochemistry, 41, 2002
1Y2M
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CRYSTAL STRUCTURE OF PHENYLALANINE AMMONIA-LYASE FROM YEAST RHODODPORIDIUM TORULOIDES
Descriptor:Phenylalanine ammonia-lyase
Authors:Wang, L., Gamez, A., Sarkissian, C.N., Straub, M., Patch, M.G., Han, G.W., Scriver, C.R., Stevens, R.C.
Deposit date:2004-11-22
Release date:2005-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-based chemical modification strategy for enzyme replacement treatment of phenylketonuria.
Mol.Genet.Metab., 86, 2005
1ZOK
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PDZ1 DOMAIN OF SYNAPSE ASSOCIATED PROTEIN 97
Descriptor:Presynaptic protein SAP97
Authors:Wang, L., Piserchio, A., Mierke, D.F.
Deposit date:2005-05-13
Release date:2005-06-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Characterization of the Intermolecular Interactions of Synapse-associated Protein-97 with the NR2B Subunit of N-Methyl-D-aspartate Receptors.
J.Biol.Chem., 280, 2005
2GP7
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ESTROGEN RELATED RECEPTOR-GAMMA LIGAND BINDING DOMAIN
Descriptor:Estrogen-related receptor gamma, CALCIUM ION
Authors:Wang, L., Zuercher, W.J., Consler, T.G., Lambert, M.H., Miller, A.B., Osband-miller, L.A., McKee, D.D., Willson, T.M., Nolte, R.T.
Deposit date:2006-04-17
Release date:2006-09-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
J.Biol.Chem., 281, 2006
2GPO
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ESTROGEN RELATED RECEPTOR-GAMMA LIGAND BINDING DOMAIN COMPLEXED WITH A SYNTHETIC PEPTIDE FROM RIP140
Descriptor:Estrogen-related receptor gamma, Nuclear receptor-interacting protein 1
Authors:Wang, L., Zuercher, W.J., Consler, T.G., Lambert, M.H., Miller, A.B., Osband-miller, L.A., McKee, D.D., Willson, T.M., Nolte, R.T.
Deposit date:2006-04-18
Release date:2006-09-26
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
J.Biol.Chem., 281, 2006
2GPP
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ESTROGEN RELATED RECEPTOR-GAMMA LIGAND BINDING DOMAIN COMPLEXED WITH A RIP140 PEPTIDE AND SYNTHETIC LIGAND GSK4716
Descriptor:Estrogen-related receptor gamma, Nuclear receptor-interacting protein 1, 4-HYDROXY-N'-(4-ISOPROPYLBENZYL)BENZOHYDRAZIDE
Authors:Wang, L., Zuercher, W.J., Consler, T.G., Lambert, M.H., Miller, A.B., Osband-miller, L.A., McKee, D.D., Willson, T.M., Nolte, R.T.
Deposit date:2006-04-18
Release date:2006-09-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
J.Biol.Chem., 281, 2006