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8CLS
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BU of 8cls by Molmil
Drosophila melanogaster insulin receptor ectodomain in complex with DILP5
Descriptor: Insulin-like receptor, Probable insulin-like peptide 5, Probable insulin-like peptide 5 A chain
Authors:Viola, C.M, Brzozowski, A.M, Shafi, T.
Deposit date:2023-02-17
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural conservation of insulin/IGF signalling axis at the insulin receptors level in Drosophila and humans.
Nat Commun, 14, 2023
1Q1L
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BU of 1q1l by Molmil
Crystal Structure of Chorismate Synthase
Descriptor: Chorismate synthase
Authors:Viola, C.M, Saridakis, V, Christendat, D, Midwest Center for Structural Genomics (MCSG)
Deposit date:2003-07-21
Release date:2003-09-30
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of chorismate synthase from Aquifex aeolicus reveals a novel beta alpha beta sandwich topology
PROTEINS: STRUCT.,FUNCT.,GENET., 54, 2004
6FF3
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BU of 6ff3 by Molmil
Crystal structure of Drosophila neural ectodermal development factor Imp-L1 with Human IGF-I
Descriptor: Insulin-like growth factor I, Neural/ectodermal development factor IMP-L2
Authors:Brzozowski, A.M, Kulahin, N, Kristensen, O, Schluckebier, G, Meyts, P.D, Viola, C.M.
Deposit date:2018-01-03
Release date:2018-09-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones.
Nat Commun, 9, 2018
5MAM
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BU of 5mam by Molmil
Human insulin in complex with serotonin
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L.
Deposit date:2016-11-03
Release date:2017-04-05
Last modified:2017-05-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules.
J. Biol. Chem., 292, 2017
5MT9
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BU of 5mt9 by Molmil
Human insulin in complex with serotonin and arginine
Descriptor: ARGININE, CHLORIDE ION, Insulin, ...
Authors:Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L.
Deposit date:2017-01-07
Release date:2017-04-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules.
J. Biol. Chem., 292, 2017
5MT3
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BU of 5mt3 by Molmil
Human insulin in complex with serotonin and arginine
Descriptor: ARGININE, CHLORIDE ION, Insulin, ...
Authors:Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L.
Deposit date:2017-01-06
Release date:2017-04-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules.
J. Biol. Chem., 292, 2017
6FEY
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BU of 6fey by Molmil
Crystal structure of Drosophila neural ectodermal development factor Imp-L2 with Drosophila DILP5 insulin
Descriptor: Neural/ectodermal development factor IMP-L2, Probable insulin-like peptide 5
Authors:Brzozowski, A.M, Kulahin, N, Kristensen, O, Schluckebier, G, Meyts, P.D.
Deposit date:2018-01-03
Release date:2018-09-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.48 Å)
Cite:Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones.
Nat Commun, 9, 2018
5E98
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BU of 5e98 by Molmil
Crystal structure of human heparanase in complex with HepMer M04S02a
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Heparanase, ...
Authors:Wu, L, Davies, G.J.
Deposit date:2015-10-14
Release date:2015-11-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22, 2015
5E9B
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BU of 5e9b by Molmil
Crystal structure of human heparanase in complex with HepMer M09S05a
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, CHLORIDE ION, ...
Authors:Wu, L, Davies, G.J.
Deposit date:2015-10-14
Release date:2015-11-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22, 2015
5E9C
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BU of 5e9c by Molmil
Crystal structure of human heparanase in complex with heparin tetrasaccharide dp4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Wu, L, Davies, G.J.
Deposit date:2015-10-15
Release date:2015-11-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22, 2015
5E8M
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BU of 5e8m by Molmil
Crystal structure of human heparanase
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Wu, L, Davies, G.J.
Deposit date:2015-10-14
Release date:2015-11-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22, 2015
5E97
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BU of 5e97 by Molmil
Glycoside Hydrolase ligand structure 1
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Wu, L, Davies, G.J.
Deposit date:2015-10-14
Release date:2015-11-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22, 2015

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