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2BYT
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BU of 2byt by Molmil
Thermus thermophilus Leucyl-tRNA synthetase complexed with a tRNAleu transcript in the post-editing conformation
Descriptor: LEUCINE, LEUCYL-TRNA SYNTHETASE, MERCURY (II) ION, ...
Authors:Cusack, S, Tukalo, M, Yaremchuk, A, Fukunaga, R, Yokoyama, S.
Deposit date:2005-08-04
Release date:2005-09-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The Crystal Structure of Leucyl-tRNA Synthetase Complexed with tRNA(Leu) in the Post-Transfer-Editing Conformation.
Nat.Struct.Mol.Biol., 12, 2005
2BTE
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BU of 2bte by Molmil
Thermus thermophilus Leucyl-tRNA synthetase complexed with a tRNAleu transcript in the post-editing conformation and a post- transfer editing substrate analogue
Descriptor: 2'-AMINO-2'-DEOXYADENOSINE, AMINOACYL-TRNA SYNTHETASE, LEUCINE, ...
Authors:Cusack, S, Tukalo, M, Yaremchuk, A, Fukunaga, R, Yokoyama, S.
Deposit date:2005-05-31
Release date:2005-09-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Crystal Structure of Leucyl-tRNA Synthetase Complexed with tRNA(Leu) in the Post-Transfer- Editing Conformation.
Nat.Struct.Mol.Biol., 12, 2005
1SER
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BU of 1ser by Molmil
THE 2.9 ANGSTROMS CRYSTAL STRUCTURE OF T. THERMOPHILUS SERYL-TRNA SYNTHETASE COMPLEXED WITH TRNA SER
Descriptor: PROTEIN (SERYL-TRNA SYNTHETASE (E.C.6.1.1.11)), TRNASER
Authors:Biou, S, Cusack, V, Yaremchuk, A, Tukalo, M.
Deposit date:1994-02-21
Release date:1994-04-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The 2.9 A crystal structure of T. thermophilus seryl-tRNA synthetase complexed with tRNA(Ser).
Science, 263, 1994
1H3N
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BU of 1h3n by Molmil
Leucyl-tRNA synthetase from Thermus thermophilus complexed with a sulphamoyl analogue of leucyl-adenylate
Descriptor: LEUCINE, LEUCYL-TRNA SYNTHETASE, SULFATE ION, ...
Authors:Cusack, S, Yaremchuk, A, Tukalo, M.
Deposit date:2002-09-11
Release date:2002-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The 2A Structure of Leucyl-tRNA Synthetase and its Complex with a Leucyl-Adenylate Analogue
Embo J., 19, 2000
1HC7
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BU of 1hc7 by Molmil
Prolyl-tRNA synthetase from Thermus thermophilus
Descriptor: PROLYL-TRNA SYNTHETASE, ZINC ION
Authors:Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2001-04-26
Release date:2001-06-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:A Succession of Substrate Induced Conformational Changes Ensures the Amino Acid Specificity of Thermus Thermophilus Prolyl-tRNA Synthetase: Comparison with Histidyl-tRNA Synthetase
J.Mol.Biol., 309, 2001
1H4S
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BU of 1h4s by Molmil
Prolyl-tRNA synthetase from Thermus thermophilus complexed with tRNApro(CGG) and a prolyl-adenylate analogue
Descriptor: '5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE, PROLYL-TRNA SYNTHETASE, SULFATE ION, ...
Authors:Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2001-05-14
Release date:2001-06-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A Succession of Substrate Induced Conformational Changes Ensures the Amino Acid Specificity of Thermus Thermophilus Prolyl-tRNA Synthetase: Comparison with Histidyl-tRNA Synthetase
J.Mol.Biol., 309, 2001
1H4T
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BU of 1h4t by Molmil
Prolyl-tRNA synthetase from Thermus thermophilus complexed with L-proline
Descriptor: PROLINE, PROLYL-TRNA SYNTHETASE, ZINC ION
Authors:Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2001-05-14
Release date:2001-06-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A Succession of Substrate Induced Conformational Changes Ensures the Amino Acid Specificity of Thermus Thermophilus Prolyl-tRNA Synthetase: Comparison with Histidyl-tRNA Synthetase
J.Mol.Biol., 309, 2001
1H4Q
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BU of 1h4q by Molmil
Prolyl-tRNA synthetase from Thermus thermophilus complexed with tRNApro(CGG), ATP and prolinol
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, PROLYL-TRNA SYNTHETASE, PYRROLIDINE-2-CARBALDEHYDE, ...
Authors:Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2001-05-13
Release date:2001-06-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Succession of Substrate Induced Conformational Changes Ensures the Amino Acid Specificity of Thermus Thermophilus Prolyl-tRNA Synthetase: Comparison with Histidyl-tRNA Synthetase
J.Mol.Biol., 309, 2001
1OBH
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BU of 1obh by Molmil
LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A PRE-TRANSFER EDITING SUBSTRATE ANALOGUE IN BOTH SYNTHETIC ACTIVE SITE AND EDITING SITE
Descriptor: LEUCYL-TRNA SYNTHETASE, MERCURY (II) ION, NORVALINE, ...
Authors:Cusack, S, Yaremchuk, A, Tukalo, M.
Deposit date:2003-01-31
Release date:2003-05-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and Mechanistic Basis of Pre- and Posttransfer Editing by Leucyl-tRNA Synthetase
Mol.Cell, 11, 2003
1OBC
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BU of 1obc by Molmil
LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A POST-TRANSFER EDITING SUBSTRATE ANALOGUE
Descriptor: 2'-AMINO-2'-DEOXYADENOSINE, LEUCINE, LEUCYL-TRNA SYNTHETASE, ...
Authors:Cusack, S, Yaremchuk, A, Tukalo, M.
Deposit date:2003-01-30
Release date:2003-05-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Mechanistic Basis of Pre- and Posttransfer Editing by Leucyl-tRNA Synthetase
Mol.Cell, 11, 2003
1H3E
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BU of 1h3e by Molmil
Tyrosyl-tRNA synthetase from Thermus thermophilus complexed with wild-type tRNAtyr(GUA) and with ATP and tyrosinol
Descriptor: 4-[(2S)-2-amino-3-hydroxypropyl]phenol, ADENOSINE-5'-TRIPHOSPHATE, TYROSYL-TRNA SYNTHETASE, ...
Authors:Cusack, S, Yaremchuk, A, Kriklivyi, I, Tukalo, M.
Deposit date:2002-08-28
Release date:2002-10-27
Last modified:2019-10-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Class I Tyrosyl-tRNA Synthetase Has a Class II Mode or tRNA Recognition
Embo J., 21, 2002
1H4V
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BU of 1h4v by Molmil
HISTIDYL-TRNA SYNTHETASE from Thermus Thermophilus (ligand free)
Descriptor: HISTIDYL-TRNA SYNTHETASE, SULFATE ION
Authors:Cusack, S, Yaremchuk, A, Tukalo, M.
Deposit date:2001-05-14
Release date:2001-06-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Succession of Substrate Induced Conformational Changes Ensures the Amino Acid Specificity of Thermus Thermophilus Prolyl-tRNA Synthetase: Comparison with Histidyl-tRNA Synthetase
J.Mol.Biol., 309, 2001
2V0G
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BU of 2v0g by Molmil
LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A tRNA(leu) transcript with 5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1- BENZOXABOROLE (AN2690) forming an adduct to the ribose of adenosine- 76 in the enzyme editing site.
Descriptor: AMINOACYL-TRNA SYNTHETASE, LEUCINE, MERCURY (II) ION, ...
Authors:Rock, F, Mao, W, Yaremchuk, A, Tukalo, M, Crepin, T, Zhou, H, Zhang, Y, Hernandez, V, Akama, T, Baker, S, Plattner, J, Shapiro, L, Martinis, S.A, Benkovic, S.J, Cusack, S, Alley, M.R.K.
Deposit date:2007-05-14
Release date:2007-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site.
Science, 316, 2007
2V0C
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BU of 2v0c by Molmil
LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A SULPHAMOYL ANALOGUE OF LEUCYL-ADENYLATE In the synthetic site and an adduct of AMP with 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (AN2690) in the editing site
Descriptor: AMINOACYL-TRNA SYNTHETASE, LEUCINE, SULFATE ION, ...
Authors:Rock, F, Mao, W, Yaremchuk, A, Tukalo, M, Crepin, T, Zhou, H, Zhang, Y, Hernandez, V, Akama, T, Baker, S, Plattner, J, Shapiro, L, Martinis, S.A, Benkovic, S.J, Cusack, S, Alley, M.R.K.
Deposit date:2007-05-14
Release date:2007-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site.
Science, 316, 2007
2I4L
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BU of 2i4l by Molmil
Rhodopseudomonas palustris prolyl-tRNA synthetase
Descriptor: Proline-tRNA ligase
Authors:Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2006-08-22
Release date:2006-10-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
2I4N
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BU of 2i4n by Molmil
Rhodopseudomonas palustris prolyl-tRNA synthetase in complex with CysAMS
Descriptor: 5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE, Proline-tRNA ligase
Authors:Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2006-08-22
Release date:2006-10-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
2I4M
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BU of 2i4m by Molmil
Rhodopseudomonas palustris prolyl-tRNA synthetase in complex with ProAMS
Descriptor: '5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE, Proline-tRNA ligase
Authors:Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2006-08-22
Release date:2006-10-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
2I4O
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BU of 2i4o by Molmil
Rhodopseudomonas palustris prolyl-tRNA synthetase in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Proline-tRNA ligase
Authors:Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2006-08-22
Release date:2006-10-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
2J3M
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BU of 2j3m by Molmil
PROLYL-TRNA SYNTHETASE FROM ENTEROCOCCUS FAECALIS COMPLEXED WITH ATP, manganese and prolinol
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, PROLYL-TRNA SYNTHETASE, ...
Authors:Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2006-08-22
Release date:2006-10-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a Cis-Editing Domain.
Structure, 14, 2006
2J3L
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BU of 2j3l by Molmil
Prolyl-tRNA synthetase from Enterococcus faecalis complexed with a prolyl-adenylate analogue ('5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE)
Descriptor: '5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE, PROLYL-TRNA SYNTHETASE, SULFATE ION
Authors:Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2006-08-22
Release date:2006-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a Cis-Editing Domain.
Structure, 14, 2006
1H3F
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BU of 1h3f by Molmil
Tyrosyl-tRNA synthetase from Thermus thermophilus complexed with tyrosinol
Descriptor: 4-[(2S)-2-amino-3-hydroxypropyl]phenol, SULFATE ION, TYROSYL-TRNA SYNTHETASE
Authors:Cusack, S, Yaremchuk, A, Kriklivyi, I, Tukalo, M.
Deposit date:2002-08-28
Release date:2002-09-12
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Class I Tyrosyl-tRNA Synthetase Has a Class II Mode or tRNA Recognition
Embo J., 21, 2002
1J1U
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BU of 1j1u by Molmil
Crystal structure of archaeal tyrosyl-tRNA synthetase complexed with tRNA(Tyr) and L-tyrosine
Descriptor: MAGNESIUM ION, TYROSINE, Tyrosyl-tRNA synthetase, ...
Authors:Kobayashi, T, Nureki, O, Ishitani, R, Tukalo, M, Cusack, S, Sakamoto, K, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-12-17
Release date:2003-06-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansion
NAT.STRUCT.BIOL., 10, 2003
1SET
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BU of 1set by Molmil
CRYSTAL STRUCTURES AT 2.5 ANGSTROMS RESOLUTION OF SERYL-TRNA SYNTHETASE COMPLEXED WITH TWO DIFFERENT ANALOGUES OF SERYL-ADENYLATE
Descriptor: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, SERYL-tRNA SYNTHETASE
Authors:Cusack, S, Belrhali, H.
Deposit date:1994-02-21
Release date:1994-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structures at 2.5 angstrom resolution of seryl-tRNA synthetase complexed with two analogs of seryl adenylate.
Science, 263, 1994
1SES
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BU of 1ses by Molmil
CRYSTAL STRUCTURES AT 2.5 ANGSTROMS RESOLUTION OF SERYL-TRNA SYNTHETASE COMPLEXED WITH TWO DIFFERENT ANALOGUES OF SERYL-ADENYLATE
Descriptor: ADENOSINE MONOPHOSPHATE, SERYL-HYDROXAMATE-ADENOSINE MONOPHOSPHATE, SERYL-tRNA SYNTHETASE
Authors:Cusack, S, Belrhali, H.
Deposit date:1994-02-21
Release date:1994-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures at 2.5 angstrom resolution of seryl-tRNA synthetase complexed with two analogs of seryl adenylate.
Science, 263, 1994
1ADJ
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BU of 1adj by Molmil
HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH HISTIDINE
Descriptor: HISTIDINE, HISTIDYL-TRNA SYNTHETASE, SULFATE ION
Authors:Cusack, S, Aberg, A.
Deposit date:1997-02-18
Release date:1997-08-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure analysis of the activation of histidine by Thermus thermophilus histidyl-tRNA synthetase.
Biochemistry, 36, 1997

 

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