Author results

1C9B
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CRYSTAL STRUCTURE OF A HUMAN TBP CORE DOMAIN-HUMAN TFIIB CORE DOMAIN COMPLEX BOUND TO AN EXTENDED, MODIFIED ADENOVIRAL MAJOR LATE PROMOTER (ADMLP)
Descriptor:ADMLP TATA-BOX DNA CONTAINING IIB RECOGNITION ELEMENT, GENERAL TRANSCRIPTION FACTOR IIB, TATA BOX BINDING PROTEIN
Authors:Tsai, F.T.F., Sigler, P.B.
Deposit date:1999-08-01
Release date:2000-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis of preinitiation complex assembly on human pol II promoters.
EMBO J., 19, 2000
1QVR
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CRYSTAL STRUCTURE ANALYSIS OF CLPB
Descriptor:ClpB protein, PLATINUM (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Lee, S., Sowa, M.E., Watanabe, Y., Sigler, P.B., Chiu, W., Yoshida, M., Tsai, F.T.F.
Deposit date:2003-08-28
Release date:2003-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Structure of ClpB: A Molecular Chaperone that Rescues Proteins from an Aggregated State
Cell(Cambridge,Mass.), 115, 2003
6N8T
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HSP104DWB CLOSED CONFORMATION
Descriptor:Heat shock protein 104, ADENOSINE-5'-TRIPHOSPHATE
Authors:Lee, S., Rho, S.H., Lee, J., Sung, N., Liu, J., Tsai, F.T.F.
Deposit date:2018-11-30
Release date:2019-01-02
Last modified:2019-01-16
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation.
Cell Rep, 26, 2019
6N8V
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HSP104DWB OPEN CONFORMATION
Descriptor:Heat shock protein 104, ADENOSINE-5'-TRIPHOSPHATE
Authors:Lee, S., Rho, S.H., Lee, J., Sung, N., Liu, J., Tsai, F.T.F.
Deposit date:2018-11-30
Release date:2019-01-02
Last modified:2019-01-16
Method:ELECTRON MICROSCOPY (5.64 Å)
Cite:Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation.
Cell Rep, 26, 2019
6N8Z
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HSP104DWB EXTENDED CONFORMATION
Descriptor:Heat shock protein 104, ADENOSINE-5'-TRIPHOSPHATE
Authors:Lee, S., Rho, S.H., Lee, J., Sung, N., Liu, J., Tsai, F.T.F.
Deposit date:2018-11-30
Release date:2019-01-02
Last modified:2019-01-16
Method:ELECTRON MICROSCOPY (9.3 Å)
Cite:Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation.
Cell Rep, 26, 2019
3M6C
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS GROEL1 APICAL DOMAIN
Descriptor:60 kDa chaperonin 1
Authors:Tsai, F.T.F., Sielaff, B., Lee, K.
Deposit date:2010-03-15
Release date:2010-12-08
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and functional conservation of Mycobacterium tuberculosis GroEL paralogs suggests that GroEL1 Is a chaperonin.
J.Mol.Biol., 405, 2011
5F5R
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TRAP1N-ADPNP
Descriptor:Heat shock protein 75 kDa, mitochondrial, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Tsai, F.T.F., Lee, S., Sung, N., Lee, J., Chang, C., Joachimiak, A.
Deposit date:2015-12-04
Release date:2016-03-02
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Mitochondrial Hsp90 is a ligand-activated molecular chaperone coupling ATP binding to dimer closure through a coiled-coil intermediate.
Proc.Natl.Acad.Sci.USA, 113, 2016
4FCT
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF CLPB
Descriptor:Chaperone protein ClpB
Authors:Biter, A.B., Lee, S., Sung, N., Tsai, F.T.F.
Deposit date:2012-05-25
Release date:2012-07-18
Last modified:2012-08-22
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structural basis for intersubunit signaling in a protein disaggregating machine.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FCV
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF CLPB
Descriptor:Chaperone protein ClpB, ADENOSINE-5'-DIPHOSPHATE
Authors:Biter, A.B., Lee, S., Sung, N., Tsai, F.T.F.
Deposit date:2012-05-25
Release date:2012-07-18
Last modified:2012-08-22
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis for intersubunit signaling in a protein disaggregating machine.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FCW
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF CLPB
Descriptor:Chaperone protein ClpB, ADENOSINE-5'-DIPHOSPHATE
Authors:Biter, A.B., Lee, S., Sung, N., Tsai, F.T.F.
Deposit date:2012-05-25
Release date:2012-07-18
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for intersubunit signaling in a protein disaggregating machine.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FD2
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF CLPB
Descriptor:Chaperone protein ClpB, ADENOSINE-5'-DIPHOSPHATE
Authors:Biter, A.B., Lee, S., Sung, N., Tsai, F.T.F.
Deposit date:2012-05-25
Release date:2012-07-18
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for intersubunit signaling in a protein disaggregating machine.
Proc.Natl.Acad.Sci.USA, 109, 2012
5F3K
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X-RAY CRYSTALLOGRAPHIC STRUCTURE OF HTRAP1 N-TERMINAL DOMAIN-APO
Descriptor:Heat shock protein 75 kDa, mitochondrial
Authors:Sung, N., Lee, J., Kim, J., Chang, C., Joachimiak, A., Lee, S., Tsai, F.T.F.
Deposit date:2015-12-02
Release date:2016-03-02
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Mitochondrial Hsp90 is a ligand-activated molecular chaperone coupling ATP binding to dimer closure through a coiled-coil intermediate.
Proc.Natl.Acad.Sci.USA, 113, 2016
5HPH
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STRUCTURE OF TRAP1 FRAGMENT
Descriptor:Heat shock protein 75 kDa, mitochondrial, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Sung, N., Chang, C., Lee, S., Tsai, F.T.F.
Deposit date:2016-01-20
Release date:2016-08-10
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.429 Å)
Cite:2.4 angstrom resolution crystal structure of human TRAP1NM, the Hsp90 paralog in the mitochondrial matrix.
Acta Crystallogr D Struct Biol, 72, 2016
5WBW
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YEAST HSP104 FRAGMENT 1-360
Descriptor:Heat shock protein 104
Authors:Lee, S.
Deposit date:2017-06-29
Release date:2018-01-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural determinants for protein unfolding and translocation by the Hsp104 protein disaggregase.
Biosci. Rep., 37, 2017
6AMN
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CRYSTAL STRUCTURE OF HSP104 N DOMAIN
Descriptor:Heat shock protein 104
Authors:Lee, S.
Deposit date:2017-08-10
Release date:2017-11-29
Method:X-RAY DIFFRACTION (2.816 Å)
Cite:Overlapping and Specific Functions of the Hsp104 N Domain Define Its Role in Protein Disaggregation.
Sci Rep, 7, 2017