Author results

2KPK
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MAGI-1 PDZ1
Descriptor:Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
Authors:Charbonnier, S., Nomine, Y., Ramirez, J., Luck, K., Stote, R.H., Trave, G., Kieffer, B., Atkinson, R.A.
Deposit date:2009-10-16
Release date:2010-10-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structural and dynamic response of MAGI-1 PDZ1 with non-canonical domain boundaries to binding of human papillomavirus (HPV) E6
J.Mol.Biol., 2011
6TWQ
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MAGI1_2 COMPLEXED WITH A 16E6 PEPTIDE
Descriptor:Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1,Annexin A2, THR-ARG-ARG-GLU-THR-GLN-LEU, ...
Authors:Gogl, G., Cousido-Siah, A., Trave, G.
Deposit date:2020-01-13
Release date:2020-04-01
Last modified:2020-05-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 2020
6TWU
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MAGI1_2 COMPLEXED WITH A PHOSPHOMIMETIC 16E6 PEPTIDE
Descriptor:Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1,Annexin A2, Protein E6, ...
Authors:Gogl, G., Cousido-Siah, A., Trave, G.
Deposit date:2020-01-13
Release date:2020-04-01
Last modified:2020-05-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 2020
6TWX
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MAGI1_2 COMPLEXED WITH A PHOSPHORYLATED 16E6 PEPTIDE
Descriptor:Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1,Annexin A2, 16E6 peptide, ...
Authors:Gogl, G., Cousido-Siah, A., Trave, G.
Deposit date:2020-01-13
Release date:2020-04-01
Last modified:2020-05-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 2020
6TWY
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MAGI1_2 COMPLEXED WITH A PHOSPHOMIMETIC RSK1 PEPTIDE
Descriptor:Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1,Annexin A2, Phosphomimetic RSK1 peptide, ...
Authors:Gogl, G., Cousido-Siah, A., Trave, G.
Deposit date:2020-01-13
Release date:2020-04-01
Last modified:2020-05-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 2020
6TWZ
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14-3-3 SIGMA COMPLEXED WITH A PHOSPHORYLATED 16E6 PEPTIDE
Descriptor:14-3-3 protein sigma, phosphorylated 16E6 peptide, D(-)-TARTARIC ACID, ...
Authors:Gogl, G., Cousido-Siah, A., Sluchanko, N.N., Trave, G.
Deposit date:2020-01-13
Release date:2020-05-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 2020
2KPL
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MAGI-1 PDZ1 / E6CT
Descriptor:Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, Protein E6
Authors:Charbonnier, S., Nomine, Y., Ramirez, J., Luck, K., Stote, R.H., Trave, G., Kieffer, B., Atkinson, R.A.
Deposit date:2009-10-16
Release date:2010-10-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structural and dynamic response of MAGI-1 PDZ1 with non-canonical domain boundaries to binding of human papillomavirus (HPV) E6
J.Mol.Biol., 2011
2LJX
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STRUCTURE OF THE MONOMERIC N-TERMINAL DOMAIN OF HPV16 E6 ONCOPROTEIN
Descriptor:Protein E6, ZINC ION
Authors:Zanier, K., Muhamed Sidi, A., Boulade-Ladame, C., Rybin, V., Chappelle, A., Atkinson, A., Kieffer, B., Trave, G.
Deposit date:2011-09-30
Release date:2012-04-04
Last modified:2012-04-25
Method:SOLUTION NMR
Cite:Solution Structure Analysis of the HPV16 E6 Oncoprotein Reveals a Self-Association Mechanism Required for E6-Mediated Degradation of p53.
Structure, 20, 2012
2LJY
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HADDOCK MODEL STRUCTURE OF THE N-TERMINAL DOMAIN DIMER OF HPV16 E6
Descriptor:Protein E6, ZINC ION
Authors:Zanier, K., Muhamed Sidi, A., Boulade-Ladame, C., Rybin, V., Chappelle, A., Atkinson, A., Kieffer, B., Trave, G.
Deposit date:2011-09-30
Release date:2012-04-04
Last modified:2012-04-25
Method:SOLUTION NMR
Cite:Solution Structure Analysis of the HPV16 E6 Oncoprotein Reveals a Self-Association Mechanism Required for E6-Mediated Degradation of p53.
Structure, 20, 2012
2LJZ
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STRUCTURE OF THE C-TERMINAL DOMAIN OF HPV16 E6 ONCOPROTEIN
Descriptor:Protein E6, ZINC ION
Authors:Zanier, K., Muhamed Sidi, A., Boulade-Ladame, C., Rybin, V., Chappelle, A., Atkinson, A., Kieffer, B., Trave, G.
Deposit date:2011-09-30
Release date:2012-04-04
Last modified:2012-04-25
Method:SOLUTION NMR
Cite:Solution Structure Analysis of the HPV16 E6 Oncoprotein Reveals a Self-Association Mechanism Required for E6-Mediated Degradation of p53.
Structure, 20, 2012
4GIZ
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CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN PAPILLOMAVIRUS ONCOPROTEIN E6 IN COMPLEX WITH LXXLL PEPTIDE OF UBIQUITIN LIGASE E6AP AT 2.55 A RESOLUTION
Descriptor:Maltose-binding periplasmic protein, UBIQUITIN LIGASE EA6P: chimeric protein, Protein E6, ...
Authors:McEwen, A.G., Zanier, K., Charbonnier, S., Poussin, P., Cura, V., Vande Pol, S., Trave, G., Cavarelli, J.
Deposit date:2012-08-09
Release date:2013-01-23
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins.
Science, 339, 2013
4XR8
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CRYSTAL STRUCTURE OF THE HPV16 E6/E6AP/P53 TERNARY COMPLEX AT 2.25 A RESOLUTION
Descriptor:Maltose-binding periplasmic protein, ubiquitin ligase E6AP, Cellular tumor antigen p53, ...
Authors:Martinez-Zapien, D., Ruiz, F.X., Mitschler, A., Podjarny, A., Trave, G., Zanier, K.
Deposit date:2015-01-20
Release date:2016-02-03
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53.
Nature, 529, 2016
6SIV
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STRUCTURE OF HPV16 E6 ONCOPROTEIN IN COMPLEX WITH MUTANT IRF3 LXXLL MOTIF
Descriptor:Maltose/maltodextrin-binding periplasmic protein,Interferon regulatory factor 3, Protein E6, ALPHA-D-GLUCOSE, ...
Authors:Suarez, I.P., Cousido-Siah, A., Bonhoure, A., Mitschler, A., Podjarny, A., Trave, G.
Deposit date:2019-08-12
Release date:2019-08-21
Method:X-RAY DIFFRACTION (1.752 Å)
Cite:Deciphering the molecular and structural interaction between IRF3 and HPV16 E6
To be published
6SJA
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STRUCTURE OF HPV16 E6 ONCOPROTEIN IN COMPLEX WITH IRF3 LXXLL MOTIF
Descriptor:Maltose/maltodextrin-binding periplasmic protein,Interferon regulatory factor 3, Protein E6, ALPHA-D-GLUCOSE, ...
Authors:Suarez, I.P., Cousido-Siah, A., Bonhoure, A., Mitschler, A., Podjarny, A., Trave, G.
Deposit date:2019-08-13
Release date:2019-09-04
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Deciphering de molecular and structural interaction between IRF3 and HPV16 E6
To be published
6SJV
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STRUCTURE OF HPV18 E6 ONCOPROTEIN IN COMPLEX WITH MUTANT E6AP LXXLL MOTIF
Descriptor:Maltodextrin-binding protein,Protein E6,Ubiquitin-protein ligase E3A, ZINC ION, MALTOSE
Authors:Suarez, I.P., Cousido-Siah, A., Bonhoure, A., Kostmann, C., Mitschler, A., Podjarny, A., Trave, G.
Deposit date:2019-08-14
Release date:2019-09-04
Method:X-RAY DIFFRACTION (2.029 Å)
Cite:Cellular target recognition by HPV18 and HPV49 oncoproteins
To be published
6SMV
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STRUCTURE OF HPV49 E6 PROTEIN IN COMPLEX WITH MAML1 LXXLL MOTIF
Descriptor:Maltose/maltodextrin-binding periplasmic protein,Protein E6,Mastermind-like protein 1, ZINC ION, MALTOTETRAOSE, ...
Authors:Suarez, I.P., Cousido-Siah, A., Bonhoure, A., Kostmann, C., Mitschler, A., Podjarny, A., Trave, G.
Deposit date:2019-08-22
Release date:2019-09-04
Last modified:2020-03-11
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Cellular target recognition by HPV18 and HPV49 oncoproteins
To be published
2FK4
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SOLUTION STRUCTURE OF THE C-TERMINAL ZINC BINDING DOMAIN OF THE HPV16 E6 ONCOPROTEIN
Descriptor:Protein E6, ZINC ION
Authors:Nomine, Y., Charbonnier, S.
Deposit date:2006-01-04
Release date:2006-01-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural and functional analysis of E6 oncoprotein: insights in the molecular pathways of human papillomavirus-mediated pathogenesis
Mol.Cell, 21, 2006
3PY7
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CRYSTAL STRUCTURE OF FULL-LENGTH BOVINE PAPILLOMAVIRUS ONCOPROTEIN E6 IN COMPLEX WITH LD1 MOTIF OF PAXILLIN AT 2.3A RESOLUTION
Descriptor:maltose-binding periplasmic protein,paxillin LD1,protein E6 chimera, ZINC ION, MALTOTRIOSE
Authors:Cavarelli, J.
Deposit date:2010-12-12
Release date:2011-12-14
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.288 Å)
Cite:Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins.
Science, 339, 2013
1VIG
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NMR STUDY OF VIGILIN, REPEAT 6, 40 STRUCTURES
Descriptor:VIGILIN
Authors:Musco, G., Stier, G., Joseph, C., Morelli, M.A.C., Nilges, M., Gibson, T.J., Pastore, A.
Deposit date:1995-11-29
Release date:1996-04-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional structure and stability of the KH domain: molecular insights into the fragile X syndrome.
Cell(Cambridge,Mass.), 85, 1996
1VIH
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NMR STUDY OF VIGILIN, REPEAT 6, MINIMIZED AVERAGE STRUCTURE
Descriptor:VIGILIN
Authors:Musco, G., Stier, G., Joseph, C., Morelli, M.A.C., Nilges, M., Gibson, T.J., Pastore, A.
Deposit date:1995-11-29
Release date:1996-04-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional structure and stability of the KH domain: molecular insights into the fragile X syndrome.
Cell(Cambridge,Mass.), 85, 1996