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3FVL
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CRYSTALLOGIC STUDIES ON THE COMPLEX OF CARBOXYPEPTIDASE A WITH INHIBITORS USING ALPHA-HYDROXY KETONE AS ZINC-BINDING GROUP
Descriptor:Carboxypeptidase A1, ZINC ION, (2R)-2-benzyl-5-hydroxy-4-oxopentanoic acid
Authors:Wang, S.F., Jin, J.-Y., Tian, G.R.
Deposit date:2009-01-16
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Optical 2-benzyl-5-hydroxy4oxopentanoic acids against carboxypeptidase A: Synthesis, kinetic evaluation and X-ray crystallographic study
CHIN.CHEM.LETT., 21, 2010
3FX6
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X-RAY CRYSTALLOGRAPHIC STUDIES ON THE COMPLEX OF CARBOXYPEPTIDASE A WITH THE INHIBITOR USING ALPHA-NITRO KETONE AS THE ZINC-BINDING GROUP
Descriptor:Carboxypeptidase A1, ZINC ION, (2R)-4,4-dihydroxy-5-nitro-2-(phenylmethyl)pentanoic acid
Authors:Wang, S.F., Jin, J.Y., Tian, G.R.
Deposit date:2009-01-20
Release date:2009-08-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Characterization of alpha-nitromethyl ketone as a new zinc-binding group based on structural analysis of its complex with carboxypeptidase A
Bioorg.Med.Chem.Lett., 19, 2009
2RFH
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CRYSTAL STRUCTURE ANALYSIS OF CPA-2-BENZYL-3-NITROPROPANOIC ACID COMPLEX
Descriptor:Carboxypeptidase A1, ZINC ION, (2R)-2-benzyl-3-nitropropanoic acid
Authors:Wang, S.-F., Zeng, Z.-H.
Deposit date:2007-09-29
Release date:2008-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Nitro as a novel zinc-binding group in the inhibition of carboxypeptidase A
Bioorg.Med.Chem., 16, 2008