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5O90
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BU of 5o90 by Molmil
Crystal structure of a P38alpha T185G mutant in complex with TAB1 peptide.
Descriptor: 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, Mitogen-activated protein kinase 14, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
Authors:Nichols, C.E, De Nicola, G.F, Thapa, D.
Deposit date:2017-06-15
Release date:2018-01-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:TAB1-Induced Autoactivation of p38 alpha Mitogen-Activated Protein Kinase Is Crucially Dependent on Threonine 185.
Mol. Cell. Biol., 38, 2018
5NZZ
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BU of 5nzz by Molmil
Crystal structure of phosphorylated p38aMAPK in complex with TAB1
Descriptor: MAGNESIUM ION, Mitogen-activated protein kinase 14, NICKEL (II) ION, ...
Authors:Nichols, C.E, De Nicola, G.F.
Deposit date:2017-05-15
Release date:2018-05-30
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The TAB1-p38 alpha complex aggravates myocardial injury and can be targeted by small molecules.
JCI Insight, 3, 2018

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