Author results

1C52
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THERMUS THERMOPHILUS CYTOCHROME-C552: A NEW HIGHLY THERMOSTABLE CYTOCHROME-C STRUCTURE OBTAINED BY MAD PHASING
Descriptor:CYTOCHROME-C552, PROTOPORPHYRIN IX CONTAINING FE
Authors:Than, M.E., Hof, P., Huber, R., Bourenkov, G.P., Bartunik, H.D., Buse, G., Soulimane, T.
Deposit date:1997-06-23
Release date:1998-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Thermus thermophilus cytochrome-c552: A new highly thermostable cytochrome-c structure obtained by MAD phasing.
J.Mol.Biol., 271, 1997
1LI1
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THE 1.9-A CRYSTAL STRUCTURE OF THE NONCOLLAGENOUS (NC1) DOMAIN OF HUMAN PLACENTA COLLAGEN IV SHOWS STABILIZATION VIA A NOVEL TYPE OF COVALENT MET-LYS CROSS-LINK
Descriptor:Collagen alpha 1(IV), Collagen alpha 2(IV), ACETATE ION
Authors:Than, M.E., Henrich, S., Huber, R., Ries, A., Mann, K., Kuhn, K., Timpl, R., Bourenkov, G.P., Bartunik, H.D., Bode, W.
Deposit date:2002-04-17
Release date:2002-05-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link.
Proc.Natl.Acad.Sci.USA, 99, 2002
1S4V
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THE 2.0 A CRYSTAL STRUCTURE OF THE KDEL-TAILED CYSTEINE ENDOPEPTIDASE FUNCTIONING IN PROGRAMMED CELL DEATH OF RICINUS COMMUNIS ENDOSPERM
Descriptor:cysteine endopeptidase, DVA-LEU-LYS-0QE peptide, SULFATE ION
Authors:Than, M.E., Helm, M., Simpson, D.J., Lottspeich, F., Huber, R., Gietl, C.
Deposit date:2004-01-19
Release date:2004-03-16
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:The 2.0 A crystal structure and substrate specificity of the KDEL-tailed cysteine endopeptidase functioning in programmed cell death of Ricinus communis endosperm.
J.Mol.Biol., 336, 2004
1B33
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STRUCTURE OF LIGHT HARVESTING COMPLEX OF ALLOPHYCOCYANIN ALPHA AND BETA CHAINS/CORE-LINKER COMPLEX AP*LC7.8
Descriptor:ALLOPHYCOCYANIN, ALPHA CHAIN, BETA CHAIN, ...
Authors:Reuter, W., Wiegand, G., Huber, R., Than, M.E.
Deposit date:1998-12-15
Release date:1999-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis at 2.2 A of orthorhombic crystals presents the asymmetry of the allophycocyanin-linker complex, AP.LC7.8, from phycobilisomes of Mastigocladus laminosus.
Proc.Natl.Acad.Sci.USA, 96, 1999
1C6O
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CRYSTAL STRUCTURE OF OXIDIZED CYTOCHROME C6 FROM THE GREEN ALGAE SCENEDESMUS OBLIQUUS
Descriptor:CYTOCHROME C6, PROTOPORPHYRIN IX CONTAINING FE
Authors:Schnackenberg, J., Than, M.E., Mann, K., Wiegand, G., Huber, R., Reuter, W.
Deposit date:1999-04-07
Release date:2000-04-12
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Amino acid sequence, crystallization and structure determination of reduced and oxidized cytochrome c6 from the green alga Scenedesmus obliquus.
J.Mol.Biol., 290, 1999
1C6R
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CRYSTAL STRUCTURE OF REDUCED CYTOCHROME C6 FROM THE GREEN ALGAE SCENEDESMUS OBLIQUUS
Descriptor:CYTOCHROME C6, CADMIUM ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Schnackenberg, J., Than, M.E., Mann, K., Wiegand, G., Huber, R., Reuter, W.
Deposit date:1999-04-06
Release date:2000-04-12
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Amino acid sequence, crystallization and structure determination of reduced and oxidized cytochrome c6 from the green alga Scenedesmus obliquus.
J.Mol.Biol., 290, 1999
1EHK
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CRYSTAL STRUCTURE OF THE ABERRANT BA3-CYTOCHROME-C OXIDASE FROM THERMUS THERMOPHILUS
Descriptor:BA3-TYPE CYTOCHROME-C OXIDASE, B-NONYLGLUCOSIDE, COPPER (II) ION, ...
Authors:Soulimane, T., Buse, G., Bourenkov, G.P., Bartunik, H.D., Huber, R., Than, M.E.
Deposit date:2000-02-21
Release date:2001-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and mechanism of the aberrant ba(3)-cytochrome c oxidase from thermus thermophilus.
EMBO J., 19, 2000
1P8J
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CRYSTAL STRUCTURE OF THE PROPROTEIN CONVERTASE FURIN
Descriptor:Furin precursor, DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Henrich, S., Cameron, A., Bourenkov, G.P., Kiefersauer, R., Huber, R., Lindberg, I., Bode, W., Than, M.E.
Deposit date:2003-05-07
Release date:2003-07-08
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Crystal Structure of the Proprotein Processing Proteinase Furin Explains its Stringent Specificity
Nat.Struct.Biol., 10, 2003
2F9N
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CRYSTAL STRUCTURE OF THE RECOMBINANT HUMAN ALPHA I TRYPTASE MUTANT K192Q/D216G IN COMPLEX WITH LEUPEPTIN
Descriptor:alpha I tryptase, Leupeptin, (R,R)-2,3-BUTANEDIOL, ...
Authors:Rohr, K.B., Selwood, T., Marquardt, U., Huber, R., Schechter, N.M., Bode, W., Than, M.E.
Deposit date:2005-12-06
Release date:2006-01-31
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-ray Structures of Free and Leupeptin-complexed Human alpha I-Tryptase Mutants: Indication for an alpha to beta-Tryptase Transition
J.Mol.Biol., 357, 2005
2F9O
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CRYSTAL STRUCTURE OF THE RECOMBINANT HUMAN ALPHA I TRYPTASE MUTANT D216G
Descriptor:Tryptase alpha-1, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE
Authors:Rohr, K.B., Selwood, T., Marquardt, U., Huber, R., Schechter, N.M., Bode, W., Than, M.E.
Deposit date:2005-12-06
Release date:2006-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray Structures of Free and Leupeptin-complexed Human alpha I-Tryptase Mutants: Indication for an alpha to beta-Tryptase Transition
J.Mol.Biol., 357, 2005
2F9P
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CRYSTAL STRUCTURE OF THE RECOMBINANT HUMAN ALPHA I TRYPTASE MUTANT D216G IN COMPLEX WITH LEUPEPTIN
Descriptor:Tryptase alpha-1, Leupeptin, (R,R)-2,3-BUTANEDIOL, ...
Authors:Rohr, K.B., Selwood, T., Marquardt, U., Huber, R., Schechter, N.M., Bode, W., Than, M.E.
Deposit date:2005-12-06
Release date:2006-01-31
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray Structures of Free and Leupeptin-complexed Human alpha I-Tryptase Mutants: Indication for an alpha to beta-Tryptase Transition
J.Mol.Biol., 357, 2005
3KTM
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STRUCTURE OF THE HEPARIN-INDUCED E1-DIMER OF THE AMYLOID PRECURSOR PROTEIN (APP)
Descriptor:Amyloid beta A4 protein, (3R)-butane-1,3-diol, SULFATE ION, ...
Authors:Dahms, S.O., Hoefgen, S., Roeser, D., Schlott, B., Guhrs, K.H., Than, M.E.
Deposit date:2009-11-25
Release date:2010-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein.
Proc.Natl.Acad.Sci.USA, 107, 2010
3QO4
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THE CRYSTAL STRUCTURE OF DEATH RECEPTOR 6
Descriptor:Tumor necrosis factor receptor superfamily member 21, ACETATE ION, SULFATE ION
Authors:Kuester, M., Kemmerzehl, S., Dahms, S.O., Roeser, D., Than, M.E.
Deposit date:2011-02-09
Release date:2011-05-18
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of death receptor 6 (DR6): a potential receptor of the amyloid precursor protein (APP).
J.Mol.Biol., 409, 2011
3UMH
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X-RAY STRUCTURE OF THE E2 DOMAIN OF THE HUMAN AMYLOID PRECURSOR PROTEIN (APP) IN COMPLEX WITH CADMIUM
Descriptor:Amyloid beta A4 protein, ACETATE ION, CADMIUM ION
Authors:Dahms, S.O., Konnig, I., Roeser, D., Guhrs, K.H., Than, M.E.
Deposit date:2011-11-13
Release date:2012-01-25
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Metal Binding Dictates Conformation and Function of the Amyloid Precursor Protein (APP) E2 Domain.
J.Mol.Biol., 416, 2012
3UMI
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X-RAY STRUCTURE OF THE E2 DOMAIN OF THE HUMAN AMYLOID PRECURSOR PROTEIN (APP) IN COMPLEX WITH ZINC
Descriptor:Amyloid beta A4 protein, ACETATE ION, ZINC ION, ...
Authors:Dahms, S.O., Konnig, I., Roeser, D., Guhrs, K.H., Than, M.E.
Deposit date:2011-11-13
Release date:2012-01-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Metal Binding Dictates Conformation and Function of the Amyloid Precursor Protein (APP) E2 Domain.
J.Mol.Biol., 416, 2012
3UMK
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X-RAY STRUCTURE OF THE E2 DOMAIN OF THE HUMAN AMYLOID PRECURSOR PROTEIN (APP) IN COMPLEX WITH COPPER
Descriptor:Amyloid beta A4 protein, ACETATE ION, COPPER (II) ION, ...
Authors:Dahms, S.O., Konnig, I., Roeser, D., Guhrs, K.H., Than, M.E.
Deposit date:2011-11-13
Release date:2012-01-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Metal Binding Dictates Conformation and Function of the Amyloid Precursor Protein (APP) E2 Domain.
J.Mol.Biol., 416, 2012
4LXC
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THE ANTIMICROBIAL PEPTIDASE LYSOSTAPHIN FROM STAPHYLOCOCCUS SIMULANS
Descriptor:Lysostaphin, ZINC ION, SULFATE ION
Authors:Sabala, I., Jagielska, E., Bardelang, P.T., Czapinska, H., Dahms, S.O., Sharpe, J.A., James, R., Than, M.E., Thomas, N.R., Bochtler, M.
Deposit date:2013-07-29
Release date:2014-07-09
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans.
Febs J., 281, 2014
4OMC
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X-RAY STRUCTURE OF HUMAN FURIN IN COMPLEX WITH THE COMPETITIVE INHIBITOR META-GUANIDINOMETHYL-PHAC-RVR-AMBA
Descriptor:Furin, meta-guanidinomethyl-phenylacetyl-Arg-Val-Arg-(amidomethyl)benzamidine, FORMIC ACID, ...
Authors:Dahms, S.O., Than, M.E.
Deposit date:2014-01-27
Release date:2014-04-09
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray Structures of Human Furin in Complex with Competitive Inhibitors.
Acs Chem.Biol., 9, 2014
4OMD
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X-RAY STRUCTURE OF HUMAN FURIN IN COMPLEX WITH THE COMPETITIVE INHIBITOR PHAC-RVR-AMBA
Descriptor:Furin, phenylacetyl-Arg-Val-Arg-(amidomethyl)benzamidine, FORMIC ACID, ...
Authors:Dahms, S.O., Than, M.E.
Deposit date:2014-01-27
Release date:2014-04-09
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray Structures of Human Furin in Complex with Competitive Inhibitors.
Acs Chem.Biol., 9, 2014
4PWQ
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HIGH-RESOLUTION CRYSTAL STRUCTURE OF THE E1-DOMAIN OF THE AMYLOID PRECURSOR PROTEIN
Descriptor:Amyloid beta A4 protein
Authors:Hoefgen, S., Dahms, S.O., Than, M.E.
Deposit date:2014-03-21
Release date:2015-02-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Amyloid Precursor Protein Shows a pH-Dependent Conformational Switch in Its E1 Domain.
J.Mol.Biol., 427, 2015
4QP5
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CATALYTIC DOMAIN OF THE ANTIMICROBIAL PEPTIDASE LYSOSTAPHIN FROM STAPHYLOCOCCUS SIMULANS CRYSTALLIZED IN THE PRESENCE OF PHOSPHATE
Descriptor:Lysostaphin, ZINC ION, PHOSPHATE ION, ...
Authors:Sabala, I., Jagielska, E., Bardelang, P.T., Czapinska, H., Dahms, S.O., Sharpe, J.A., James, R., Than, M.E., Thomas, N.R., Bochtler, M.
Deposit date:2014-06-22
Release date:2014-07-16
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans.
Febs J., 281, 2014
4QPB
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CATALYTIC DOMAIN OF THE ANTIMICROBIAL PEPTIDASE LYSOSTAPHIN FROM STAPHYLOCOCCUS SIMULANS CRYSTALLIZED IN THE ABSENCE OF PHOSPHATE
Descriptor:Lysostaphin, ZINC ION, 1,2-ETHANEDIOL
Authors:Sabala, I., Jagielska, E., Bardelang, P.T., Czapinska, H., Dahms, S.O., Sharpe, J.A., James, R., Than, M.E., Thomas, N.R., Bochtler, M.
Deposit date:2014-06-22
Release date:2014-07-09
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans.
Febs J., 281, 2014
4RD9
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X-RAY STRUCTURE OF THE APO FORM OF THE AMYLOID PRECURSOR PROTEIN-LIKE PROTEIN 1 (APLP1) E2 DOMAIN
Descriptor:Amyloid-like protein 1
Authors:Dahms, S.O., Than, M.E.
Deposit date:2014-09-18
Release date:2015-03-11
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes.
Acta Crystallogr.,Sect.D, 71, 2015
4RDA
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X-RAY STRUCTURE OF THE AMYLOID PRECURSOR PROTEIN-LIKE PROTEIN 1 (APLP1) E2 DOMAIN IN COMPLEX WITH A HEPARIN DODECASACCHARIDE
Descriptor:Amyloid-like protein 1, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid, N,O6-DISULFO-GLUCOSAMINE, ...
Authors:Dahms, S.O., Than, M.E.
Deposit date:2014-09-18
Release date:2015-03-11
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes.
Acta Crystallogr.,Sect.D, 71, 2015
4RYD
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X-RAY STRUCTURE OF HUMAN FURIN IN COMPLEX WITH THE COMPETITIVE INHIBITOR PARA-GUANIDINOMETHYL-PHAC-R-TLE-R-AMBA
Descriptor:Furin, para-guanidinomethyl-phenylacetyl-Arg-(3-methylvaline)-Arg-(amidomethyl)benzamidine, FORMIC ACID, ...
Authors:Dahms, S.O., Than, M.E.
Deposit date:2014-12-15
Release date:2015-05-27
Last modified:2015-07-15
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Novel Furin Inhibitors with Potent Anti-infectious Activity.
Chemmedchem, 10, 2015
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