Author results

4XLO
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CRYSTAL STRUCTURE OF ENCM (CRYSTALLIZED WITH 4 MM NADPH)
Descriptor:FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Teufel, R.
Deposit date:2015-01-13
Release date:2015-01-28
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
Nature, 503, 2013
3W8W
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THE CRYSTAL STRUCTURE OF ENCM
Descriptor:Putative FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Teufel, R., Miyanaga, A., Stull, F., Michaudel, Q., Louie, G., Noel, J.P., Baran, P.S., Palfey, B., Moore, B.S.
Deposit date:2013-03-22
Release date:2013-10-30
Last modified:2013-12-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
Nature, 503, 2013
3W8X
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THE COMPLEX STRUCTURE OF ENCM WITH TRIFLUOROTRIKETIDE
Descriptor:Putative FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE, 6,6,6-trifluoro-1-phenylhexane-1,3,5-trione, ...
Authors:Teufel, R., Miyanaga, A., Stull, F., Michaudel, Q., Louie, G., Noel, J.P., Baran, P.S., Palfey, B., Moore, B.S.
Deposit date:2013-03-22
Release date:2013-10-30
Last modified:2013-12-11
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
Nature, 503, 2013
3W8Z
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THE COMPLEX STRUCTURE OF ENCM WITH HYDROXYTETRAKETIDE
Descriptor:Putative FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE, (7S)-7-hydroxy-1-phenyloctane-1,3,5-trione
Authors:Teufel, R., Miyanaga, A., Stull, F., Michaudel, Q., Louie, G., Noel, J.P., Baran, P.S., Palfey, B., Moore, B.S.
Deposit date:2013-03-22
Release date:2013-10-30
Last modified:2013-12-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
Nature, 503, 2013
6FOQ
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THE CRYSTAL STRUCTURE OF ENCM COMPLEXED WITH DIOXYGEN UNDER 15 BAR OF OXYGEN PRESSURE.
Descriptor:Putative FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE, OXYGEN MOLECULE
Authors:Saleem-Batcha, R., Teufel, R.
Deposit date:2018-02-08
Release date:2018-05-02
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (1.386 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FOW
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THE CRYSTAL STRUCTURE OF ENCM COMPLEXED WITH DIOXYGEN UNDER 10 BAR OF OXYGEN PRESSURE.
Descriptor:Putative FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE, OXYGEN MOLECULE
Authors:Saleem-Batcha, R., Teufel, R.
Deposit date:2018-02-08
Release date:2018-05-02
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FP3
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THE CRYSTAL STRUCTURE OF ENCM COMPLEXED WITH DIOXYGEN UNDER 5 BAR OF OXYGEN PRESSURE.
Descriptor:Putative FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE, OXYGEN MOLECULE
Authors:Saleem-Batcha, R., Teufel, R.
Deposit date:2018-02-09
Release date:2018-05-02
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (1.976 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FY8
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THE CRYSTAL STRUCTURE OF ENCM BROMIDE SOAK
Descriptor:Putative FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE, BROMIDE ION
Authors:Saleem-Batcha, R., Teufel, R.
Deposit date:2018-03-11
Release date:2018-05-02
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FY9
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THE CRYSTAL STRUCTURE OF ENCM COMPLEX WITH XENON UNDER 15 BARS XE PRESSURE
Descriptor:Putative FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE, XENON
Authors:Saleem-Batcha, R., Teufel, R.
Deposit date:2018-03-11
Release date:2018-05-02
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FYA
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THE CRYSTAL STRUCTURE OF ENCM UNDER ANAEROBIC CONDITIONS
Descriptor:Putative FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Saleem-Batcha, R., Teufel, R.
Deposit date:2018-03-11
Release date:2018-05-02
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FYB
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THE CRYSTAL STRUCTURE OF ENCM L144M MUTANT
Descriptor:Putative FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Saleem-Batcha, R., Teufel, R.
Deposit date:2018-03-11
Release date:2018-05-02
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (1.882 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FYC
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THE CRYSTAL STRUCTURE OF ENCM L144M MUTANT COMPLEX WITH DIOXYGEN UNDER 15 BARS O2 PRESSURE
Descriptor:Putative FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE, OXYGEN MOLECULE
Authors:Saleem-Batcha, R., Teufel, R.
Deposit date:2018-03-11
Release date:2018-05-02
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FYD
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THE CRYSTAL STRUCTURE OF ENCM T139V MUTANT
Descriptor:Putative FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Saleem-Batcha, R., Teufel, R.
Deposit date:2018-03-11
Release date:2018-05-02
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FYE
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THE CRYSTAL STRUCTURE OF ENCM H138T MUTANT
Descriptor:Putative FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Saleem-Batcha, R., Teufel, R.
Deposit date:2018-03-11
Release date:2018-05-02
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FYF
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THE CRYSTAL STRUCTURE OF ENCM V135M MUTANT
Descriptor:Putative FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Saleem-Batcha, R., Teufel, R.
Deposit date:2018-03-11
Release date:2018-05-02
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FYG
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THE CRYSTAL STRUCTURE OF ENCM V135T MUTANT
Descriptor:Putative FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Saleem-Batcha, R., Teufel, R.
Deposit date:2018-03-11
Release date:2018-05-02
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6SGG
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CRYSTAL STRUCTURE OF MONOOXYGENASE RUTA COMPLEXED WITH DIOXYGEN UNDER 1.5 MPA / 15 BARS OF OXYGEN PRESSURE.
Descriptor:Pyrimidine monooxygenase RutA, SULFATE ION, GLYCEROL, ...
Authors:Saleem-Batcha, R., Matthews, A., Teufel, R.
Deposit date:2019-08-04
Release date:2020-02-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of RutA-FMN complex with dioxygen under 1.5 MPa / 15 bar of oxygen pressure.
To Be Published
6SGL
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CRYSTAL STRUCTURE OF MONOOXYGENASE RUTA COMPLEXED WITH URACIL UNDER ATMOSPHERIC PRESSURE.
Descriptor:Pyrimidine monooxygenase RutA, FLAVIN MONONUCLEOTIDE, URACIL, ...
Authors:Saleem-Batcha, R., Matthews, A., Teufel, R.
Deposit date:2019-08-05
Release date:2020-02-05
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:The crystal structure of RutA-FMN complex with dioxygen under 1.5 MPa / 15 bar of oxygen pressure.
To Be Published
6SGM
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CRYSTAL STRUCTURE OF MONOOXYGENASE RUTA COMPLEXED WITH 4-THIOURACIL.
Descriptor:Pyrimidine monooxygenase RutA, FLAVIN MONONUCLEOTIDE, 4-Thiouracil
Authors:Saleem-Batcha, R., Matthews, A., Teufel, R.
Deposit date:2019-08-05
Release date:2020-02-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of RutA-FMN complex with dioxygen under 1.5 MPa / 15 bar of oxygen pressure.
To Be Published
6SGN
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CRYSTAL STRUCTURE OF MONOOXYGENASE RUTA COMPLEXED WITH 2,4-DIMETHOXYPYRIMIDINE.
Descriptor:Pyrimidine monooxygenase RutA, FLAVIN MONONUCLEOTIDE, 2,4-dimethoxypyrimidine
Authors:Saleem-Batcha, R., Matthews, A., Teufel, R.
Deposit date:2019-08-05
Release date:2020-02-05
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:The crystal structure of RutA-FMN complex with dioxygen under 1.5 MPa / 15 bar of oxygen pressure.
To Be Published
6SL9
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HIGH RESOLUTION APO STRUCTURE OF ISOMERASE PAAG
Descriptor:Enoyl-CoA hydratase/carnithine racemase, GLYCEROL
Authors:Saleem-Batcha, R., Spieker, M., Teufel, R.
Deposit date:2019-08-19
Release date:2019-12-11
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Structural and Mechanistic Basis of an Oxepin-CoA Forming Isomerase in Bacterial Primary and Secondary Metabolism.
Acs Chem.Biol., 14, 2019
6SLA
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CRYSTAL STRUCTURE OF ISOMERASE PAAG MUTANT - D136N WITH OXEPIN-COA
Descriptor:Enoyl-CoA hydratase/carnithine racemase, ~{S}-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] 2-(2,5-dihydrooxepin-7-yl)ethanethioate
Authors:Saleem-Batcha, R., Spieker, M., Teufel, R.
Deposit date:2019-08-19
Release date:2019-12-11
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural and Mechanistic Basis of an Oxepin-CoA Forming Isomerase in Bacterial Primary and Secondary Metabolism.
Acs Chem.Biol., 14, 2019
6SLB
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CRYSTAL STRUCTURE OF ISOMERASE PAAG WITH TRANS-3,4-DIDEHYDROADIPYL-COA
Descriptor:Enoyl-CoA hydratase/carnithine racemase, (~{E})-6-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethylsulfanyl]-6-oxidanylidene-hex-3-enoic acid
Authors:Saleem-Batcha, R., Spieker, M., Teufel, R.
Deposit date:2019-08-19
Release date:2019-12-11
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structural and Mechanistic Basis of an Oxepin-CoA Forming Isomerase in Bacterial Primary and Secondary Metabolism.
Acs Chem.Biol., 14, 2019
6TEE
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CRYSTAL STRUCTURE OF MONOOXYGENASE RUTA UNDER ANAEROBIC CONDITIONS.
Descriptor:Pyrimidine monooxygenase RutA, GLYCEROL, FLAVIN MONONUCLEOTIDE
Authors:Saleem-Batcha, R., Matthews, A., Teufel, R.
Deposit date:2019-11-11
Release date:2020-02-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of RutA-FMN complex with dioxygen under 1.5 MPa / 15 bar of oxygen pressure.
To Be Published
6TEF
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CRYSTAL STRUCTURE OF MONOOXYGENASE RUTA COMPLEXED WITH DIOXYGEN UNDER 0.5 MPA / 5 BARS OF OXYGEN PRESSURE.
Descriptor:Pyrimidine monooxygenase RutA, SULFATE ION, GLYCEROL, ...
Authors:Saleem-Batcha, R., Matthews, A., Teufel, R.
Deposit date:2019-11-11
Release date:2020-02-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of RutA-FMN complex with dioxygen under 1.5 MPa / 15 bar of oxygen pressure.
To Be Published
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