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1S0V
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BU of 1s0v by Molmil
Structural basis for substrate selection by T7 RNA polymerase
Descriptor: 5'-D(*G*GP*GP*AP*AP*TP*CP*GP*AP*TP*AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*C)-3', 5'-R(*AP*AP*CP*U*GP*CP*GP*GP*CP*GP*AP*U)-3', ...
Authors:Temiakov, D, Patlan, V, Anikin, M, McAllister, W.T, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-01-05
Release date:2004-02-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for substrate selection by t7 RNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
2A6H
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BU of 2a6h by Molmil
Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic sterptolydigin
Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Temiakov, D, Zenkin, N, Vassylyeva, M.N, Perederina, A, Tahirov, T.H, Savkina, M, Zorov, S, Nikiforov, V, Igarashi, N, Matsugaki, N, Wakatsuki, S, Severinov, K, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-02
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of transcription inhibition by antibiotic streptolydigin.
Mol.Cell, 19, 2005
8T7E
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BU of 8t7e by Molmil
Cryo-EM structure of the Backtracking Initiation Complex (VII) of Human Mitochondrial DNA Polymerase Gamma
Descriptor: DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ...
Authors:Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D.
Deposit date:2023-06-20
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Structural basis for DNA proofreading.
Nat Commun, 14, 2023
3SPA
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BU of 3spa by Molmil
Crystal Structure of Human Mitochondrial RNA Polymerase
Descriptor: CHLORIDE ION, DNA-directed RNA polymerase, mitochondrial, ...
Authors:Ringel, R, Sologub, M, Morozov, Y.I, Litonin, D, Cramer, P, Temiakov, D.
Deposit date:2011-07-01
Release date:2011-09-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of human mitochondrial RNA polymerase
Nature, 478, 2011
4BOC
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BU of 4boc by Molmil
Structure of mitochondrial RNA polymerase elongation complex
Descriptor: 5'-D(*CP*AP*TP*GP*GP*GP*GP*TP*AP*AP*TP*TP*AP*TP *TP*TP*CP*GP*AP*CP*GP*CP*CP*AP*GP*AP*CP*G)-3', 5'-D(*CP*GP*TP*CP*TP*GP*GP*CP*GP*TP*GP*CP*GP*CP *GP*CP*CP*GP*CP*TP*AP*CP*CP*CP*CP*AP*TP*G)-3', 5'-R(*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP)-3', ...
Authors:Schwinghammer, K, Cheung, A, Morozov, Y, Agaronyan, K, Temiakov, D, Cramer, P.
Deposit date:2013-05-18
Release date:2013-09-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of Human Mitochondrial RNA Polymerase Elongation Complex
Nat.Struct.Mol.Biol., 20, 2013
7A9X
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BU of 7a9x by Molmil
Structure of yeast Rmd9p in complex with 16nt target RNA
Descriptor: CHLORIDE ION, Protein RMD9, mitochondrial, ...
Authors:Hillen, H.S, Markov, D.A, Ireneusz, W.D, Hofmann, K.B, Cowan, A.T, Jones, J.L, Temiakov, D, Cramer, P, Anikin, M.
Deposit date:2020-09-02
Release date:2021-04-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3'-UTRs of yeast mitochondrial mRNAs.
Proc.Natl.Acad.Sci.USA, 118, 2021
7A9W
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BU of 7a9w by Molmil
Structure of yeast Rmd9p in complex with 20nt target RNA
Descriptor: CHLORIDE ION, Protein RMD9, mitochondrial, ...
Authors:Hillen, H.S, Markov, D.A, Ireneusz, W.D, Hofmann, K.B, Cowan, A.T, Jones, J.L, Temiakov, D, Cramer, P, Anikin, M.
Deposit date:2020-09-02
Release date:2021-04-07
Last modified:2021-05-05
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3'-UTRs of yeast mitochondrial mRNAs.
Proc.Natl.Acad.Sci.USA, 118, 2021
8G5L
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BU of 8g5l by Molmil
Cryo-EM structure of the Primer Separation Complex (IX) of Human Mitochondrial DNA Polymerase Gamma
Descriptor: DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ...
Authors:Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D.
Deposit date:2023-02-13
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for DNA proofreading.
Nat Commun, 14, 2023
8G5O
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BU of 8g5o by Molmil
Cryo-EM structure of the Guide loop Engagement Complex (IV) of Human Mitochondrial DNA Polymerase Gamma
Descriptor: DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ...
Authors:Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D.
Deposit date:2023-02-13
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Structural basis for DNA proofreading.
Nat Commun, 14, 2023
8G5N
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BU of 8g5n by Molmil
Cryo-EM structure of the Guide loop Engagement Complex (VI) of Human Mitochondrial DNA Polymerase Gamma
Descriptor: DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ...
Authors:Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D.
Deposit date:2023-02-13
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Structural basis for DNA proofreading.
Nat Commun, 14, 2023
8G5I
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BU of 8g5i by Molmil
Cryo-EM structure of the Mismatch Sensing Complex (I) of Human Mitochondrial DNA Polymerase Gamma
Descriptor: DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ...
Authors:Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D.
Deposit date:2023-02-13
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Structural basis for DNA proofreading.
Nat Commun, 14, 2023
8G5M
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BU of 8g5m by Molmil
Cryo-EM structure of the Mismatch Locking Complex (III) of Human Mitochondrial DNA Polymerase Gamma
Descriptor: DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ...
Authors:Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D.
Deposit date:2023-02-13
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Structural basis for DNA proofreading.
Nat Commun, 14, 2023
8G5K
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BU of 8g5k by Molmil
Cryo-EM structure of the Wedge Alignment Complex (VIII) of Human Mitochondrial DNA Polymerase Gamma
Descriptor: DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ...
Authors:Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D.
Deposit date:2023-02-13
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for DNA proofreading.
Nat Commun, 14, 2023
8G5P
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BU of 8g5p by Molmil
Cryo-EM structure of the Guide loop Engagement Complex (V) of Human Mitochondrial DNA Polymerase Gamma
Descriptor: DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ...
Authors:Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D.
Deposit date:2023-02-13
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:Structural basis for DNA proofreading.
Nat Commun, 14, 2023
8G5J
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BU of 8g5j by Molmil
Cryo-EM structure of the Mismatch Uncoupling Complex (II) of Human Mitochondrial DNA Polymerase Gamma
Descriptor: DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ...
Authors:Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D.
Deposit date:2023-02-13
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Structural basis for DNA proofreading.
Nat Commun, 14, 2023
6ERQ
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BU of 6erq by Molmil
Structure of the human mitochondrial transcription initiation complex at the HSP promoter
Descriptor: DNA-directed RNA polymerase, mitochondrial, Dimethyladenosine transferase 2, ...
Authors:Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P.
Deposit date:2017-10-18
Release date:2017-11-15
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
6ERO
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BU of 6ero by Molmil
Structure of human TFB2M
Descriptor: CHLORIDE ION, Dimethyladenosine transferase 2, mitochondrial,Dimethyladenosine transferase 2, ...
Authors:Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P.
Deposit date:2017-10-18
Release date:2017-11-15
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
6ERP
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BU of 6erp by Molmil
Structure of the human mitochondrial transcription initiation complex at the LSP promoter
Descriptor: DNA-directed RNA polymerase, mitochondrial, Dimethyladenosine transferase 2, ...
Authors:Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P.
Deposit date:2017-10-18
Release date:2017-11-15
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (4.502 Å)
Cite:Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
5OL9
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BU of 5ol9 by Molmil
Structure of human mitochondrial transcription elongation factor (TEFM) N-terminal domain
Descriptor: ACETATE ION, Transcription elongation factor, mitochondrial
Authors:Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D.
Deposit date:2017-07-27
Release date:2017-10-18
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.302 Å)
Cite:Mechanism of Transcription Anti-termination in Human Mitochondria.
Cell, 171, 2017
5OLA
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BU of 5ola by Molmil
Structure of mitochondrial transcription elongation complex in complex with elongation factor TEFM
Descriptor: DNA (30-MER), DNA (5'-D(P*AP*TP*GP*GP*TP*GP*TP*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*GP*AP*AP*C)-3'), DNA-directed RNA polymerase, ...
Authors:Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D.
Deposit date:2017-07-27
Release date:2017-10-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.904 Å)
Cite:Mechanism of Transcription Anti-termination in Human Mitochondria.
Cell, 171, 2017
5OL8
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BU of 5ol8 by Molmil
Structure of human mitochondrial transcription elongation factor (TEFM) C-terminal domain
Descriptor: GLYCEROL, Transcription elongation factor, mitochondrial
Authors:Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D.
Deposit date:2017-07-27
Release date:2017-10-18
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanism of Transcription Anti-termination in Human Mitochondria.
Cell, 171, 2017
1H38
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BU of 1h38 by Molmil
Structure of a T7 RNA polymerase elongation complex at 2.9A resolution
Descriptor: 5'-D(*GP*GP*GP*AP*AP*TP*CP*GP*AP*CP *AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*CP)-3', 5'-R(*AP*AP*CP*UP*GP*CP*GP*GP*CP*GP *AP*U)-3', ...
Authors:Tahirov, T.H, Temyakov, D, Anikin, M, Patlan, V, McAllister, W.T, Vassylyev, D.G, Yokoyama, S.
Deposit date:2002-08-24
Release date:2002-11-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of a T7 RNA Polymerase Elongation Complex at 2.9 A Resolution
Nature, 420, 2002
2A6E
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BU of 2a6e by Molmil
Crystal structure of the T. Thermophilus RNA polymerase holoenzyme
Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-02
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
Cell(Cambridge,Mass.), 122, 2005

217705

PDB entries from 2024-03-27

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