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1SJJ
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CRYO-EM STRUCTURE OF CHICKEN GIZZARD SMOOTH MUSCLE ALPHA-ACTININ
Descriptor:actinin
Authors:Liu, J., Taylor, D.W., Taylor, K.A.
Deposit date:2004-03-03
Release date:2004-03-23
Last modified:2018-07-18
Method:ELECTRON CRYSTALLOGRAPHY (20 Å)
Cite:A 3-D Reconstruction of Smooth Muscle alpha-Actinin by CryoEm Reveals Two Different Conformations at the Actin-binding Region.
J.Mol.Biol., 338, 2004
2DFS
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3-D STRUCTURE OF MYOSIN-V INHIBITED STATE
Descriptor:Myosin-5A, Calmodulin
Authors:Liu, J., Taylor, D.W., Krementsova, E.B., Trybus, K.M., Taylor, K.A.
Deposit date:2006-03-03
Release date:2006-04-25
Last modified:2011-07-13
Method:ELECTRON CRYSTALLOGRAPHY (24 Å)
Cite:Three-dimensional structure of the myosin V inhibited state by cryoelectron tomography
Nature, 442, 2006
4CMP
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CRYSTAL STRUCTURE OF S. PYOGENES CAS9
Descriptor:CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, SULFATE ION, MAGNESIUM ION
Authors:Jinek, M., Jiang, F., Taylor, D.W., Sternberg, S.H., Kaya, E., Ma, E., Anders, C., Hauer, M., Zhou, K., Lin, S., Kaplan, M., Iavarone, A.T., Charpentier, E., Nogales, E., Doudna, J.A.
Deposit date:2014-01-16
Release date:2014-02-12
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation.
Science, 343, 2014
4CMQ
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CRYSTAL STRUCTURE OF MN-BOUND S.PYOGENES CAS9
Descriptor:CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MANGANESE (II) ION, SULFATE ION
Authors:Jinek, M., Jiang, F., Taylor, D.W., Sternberg, S.H., Kaya, E., Ma, E., Anders, C., Hauer, M., Zhou, K., Lin, S., Kaplan, M., Iavarone, A.T., Charpentier, E., Nogales, E., Doudna, J.A.
Deposit date:2014-01-17
Release date:2014-02-12
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Structures of Cas9 Endonucleases Reveal RNA- Mediated Conformational Activation
Science, 343, 2014
6MDR
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CRYO-EM STRUCTURE OF THE CERU+32/GFP-17 PROTOMER
Descriptor:Ceru+32, GFP-17
Authors:Simon, A.J., Zhou, Y., Ramasubramani, V., Glaser, J., Pothukuchy, A., Golihar, J., Gerberich, J.C., Leggere, J.C., Morrow, B.R., Jung, C., Glotzer, S.C., Taylor, D.W., Ellington, A.D.
Deposit date:2018-09-05
Release date:2019-01-23
Last modified:2019-03-06
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Supercharging enables organized assembly of synthetic biomolecules.
Nat Chem, 11, 2019
6N8J
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CRYO-EM STRUCTURE OF LATE NUCLEAR (LN) PRE-60S RIBOSOMAL SUBUNIT
Descriptor:60S ribosomal protein L5, 60S ribosomal protein L11-A, 60S ribosomal protein L2-A, ...
Authors:Zhou, Y., Musalgaonkar, S., Johnson, A.W., Taylor, D.W.
Deposit date:2018-11-29
Release date:2019-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
6N8K
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CRYO-EM STRUCTURE OF EARLY CYTOPLASMIC-IMMEDIATE (ECI) PRE-60S RIBOSOMAL SUBUNIT
Descriptor:Ribosomal Protein uL1, 60S ribosomal export protein NMD3, 60S ribosomal protein L2-A, ...
Authors:Zhou, Y., Musalgaonkar, S., Johnson, A.W., Taylor, D.W.
Deposit date:2018-11-29
Release date:2019-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
6N8L
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CRYO-EM STRUCTURE OF EARLY CYTOPLASMIC-LATE (ECL) PRE-60S RIBOSOMAL SUBUNIT
Descriptor:60S ribosomal export protein NMD3, Ribosomal Protein uL1, 60S ribosomal protein L2-A, ...
Authors:Zhou, Y., Musalgaonkar, S., Johnson, A.W., Taylor, D.W.
Deposit date:2018-11-29
Release date:2019-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
6N8M
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CRYO-EM STRUCTURE OF PRE-LSG1 (PL) PRE-60S RIBOSOMAL SUBUNIT
Descriptor:Saccharomyces cerevisiae S288C 35S pre-ribosomal RNA (RDN37-1), miscRNA, 5S rRNA, ...
Authors:Zhou, Y., Musalgaonkar, S., Johnson, A.W., Taylor, D.W.
Deposit date:2018-11-29
Release date:2019-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
6N8N
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CRYO-EM STRUCTURE OF LSG1-ENGAGED (LE) PRE-60S RIBOSOMAL SUBUNIT
Descriptor:Saccharomyces cerevisiae S288C 35S pre-ribosomal RNA (RDN37-1), miscRNA, 5S rRNA, ...
Authors:Zhou, Y., Musalgaonkar, S., Johnson, A.W., Taylor, D.W.
Deposit date:2018-11-29
Release date:2019-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
6N8O
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CRYO-EM STRUCTURE OF RPL10-INSERTED (RI) PRE-60S RIBOSOMAL SUBUNIT
Descriptor:Saccharomyces cerevisiae S288C 35S pre-ribosomal RNA (RDN37-1), miscRNA, 5S rRNA, ...
Authors:Zhou, Y., Musalgaonkar, S., Johnson, A.W., Taylor, D.W.
Deposit date:2018-11-29
Release date:2019-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
3J04
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EM STRUCTURE OF THE HEAVY MEROMYOSIN SUBFRAGMENT OF CHICK SMOOTH MUSCLE MYOSIN WITH REGULATORY LIGHT CHAIN IN PHOSPHORYLATED STATE
Descriptor:Myosin-11, Myosin regulatory light chain 2, smooth muscle major isoform, ...
Authors:Baumann, B.A.J., Taylor, D., Huang, Z., Tama, F., Fagnant, P.M., Trybus, K., Taylor, K.
Deposit date:2011-02-18
Release date:2011-11-16
Last modified:2012-02-01
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Phosphorylated smooth muscle heavy meromyosin shows an open conformation linked to activation.
J.Mol.Biol., 415, 2012
6BIH
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THE STRUCTURE OF THE ACTIN-SMOOTH MUSCLE MYOSIN MOTOR DOMAIN COMPLEX IN THE RIGOR STATE
Descriptor:Myosin-11, Actin, alpha skeletal muscle, ...
Authors:Taylor, K.A., Banerjee, C., Hu, Z.
Deposit date:2017-11-02
Release date:2018-09-19
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (6 Å)
Cite:The structure of the actin-smooth muscle myosin motor domain complex in the rigor state.
J. Struct. Biol., 200, 2017
3V7A
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STRUCTURAL BASIS FOR BROAD DETECTION OF GENOGROUP II NOROVIRUSES BY A MONOCLONAL ANTIBODY THAT BINDS TO A SITE OCCLUDED IN THE VIRAL PARTICLE
Descriptor:5B18 heavy chain, 5B18 kappa chain, Capsid
Authors:Hansman, G.S., Mclellan, J.S., Kwong, P.D.
Deposit date:2011-12-20
Release date:2012-02-08
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (3.297 Å)
Cite:Structural Basis for Broad Detection of Genogroup II Noroviruses by a Monoclonal Antibody That Binds to a Site Occluded in the Viral Particle.
J.Virol., 86, 2012
4OGC
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CRYSTAL STRUCTURE OF THE TYPE II-C CAS9 ENZYME FROM ACTINOMYCES NAESLUNDII
Descriptor:HNH endonuclease domain protein, ZINC ION, MANGANESE (II) ION, ...
Authors:Jiang, F., Ma, E., Lin, S., Doudna, J.A.
Deposit date:2014-01-15
Release date:2014-02-12
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
Science, 343, 2014
4OGE
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CRYSTAL STRUCTURE OF THE TYPE II-C CAS9 ENZYME FROM ACTINOMYCES NAESLUNDII
Descriptor:HNH endonuclease domain protein, ZINC ION, MAGNESIUM ION, ...
Authors:Jiang, F., Ma, E., Lin, S., Doudna, J.A.
Deposit date:2014-01-15
Release date:2014-02-12
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
Science, 343, 2014
5F9R
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CRYSTAL STRUCTURE OF CATALYTICALLY-ACTIVE STREPTOCOCCUS PYOGENES CRISPR-CAS9 IN COMPLEX WITH SINGLE-GUIDED RNA AND DOUBLE-STRANDED DNA PRIMED FOR TARGET DNA CLEAVAGE
Descriptor:CRISPR-associated endonuclease Cas9/Csn1, RNA (116-MER), DNA (30-MER), ...
Authors:Jiang, F., Doudna, J.A.
Deposit date:2015-12-10
Release date:2016-01-27
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage.
Science, 351, 2016