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2L98
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BU of 2l98 by Molmil
Structure of trans-Resveratrol in complex with the cardiac regulatory protein Troponin C
Descriptor: CALCIUM ION, RESVERATROL, Troponin C, ...
Authors:Sykes, B.D, Pineda-Sanabria, S.E, Robertson, I.M.
Deposit date:2011-02-02
Release date:2011-03-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of trans-Resveratrol in Complex with the Cardiac Regulatory Protein Troponin C.
Biochemistry, 50, 2011
7UH9
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BU of 7uh9 by Molmil
NMR structure of the cNTnC-cTnI chimera bound to W8
Descriptor: CALCIUM ION, N-(7-aminoheptyl)-5-chloronaphthalene-1-sulfonamide, Troponin C, ...
Authors:Cai, F, Kampourakis, T, Cockburn, K.T, Sykes, B.D.
Deposit date:2022-03-26
Release date:2022-06-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Drugging the Sarcomere, a Delicate Balance: Position of N-Terminal Charge of the Inhibitor W7.
Acs Chem.Biol., 17, 2022
7JGI
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BU of 7jgi by Molmil
NMR structure of the cNTnC-cTnI chimera bound to A7
Descriptor: 7-{[(5-chloronaphthalen-1-yl)sulfonyl]amino}heptanoic acid, CALCIUM ION, Troponin C, ...
Authors:Cai, F, Robertson, I.M, Kampourakis, T, Klein, B.A, Sykes, B.D.
Deposit date:2020-07-19
Release date:2020-09-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Role of Electrostatics in the Mechanism of Cardiac Thin Filament Based Sensitizers.
Acs Chem.Biol., 15, 2020
7KAA
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BU of 7kaa by Molmil
NMR solution structures of tirasemtiv drug bound to a fast skeletal troponin C-troponin I complex
Descriptor: 6-ethynyl-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2-ol, CALCIUM ION, Troponin C, ...
Authors:Mercier, P, Li, M.X, Hartman, J.J, Sykes, B.D.
Deposit date:2020-09-30
Release date:2021-03-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Basis of Tirasemtiv Activation of Fast Skeletal Muscle.
J.Med.Chem., 64, 2021
3CTN
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BU of 3ctn by Molmil
STRUCTURE OF CALCIUM-SATURATED CARDIAC TROPONIN C, NMR, 30 STRUCTURES
Descriptor: CALCIUM ION, TROPONIN C
Authors:Sia, S.K, Li, M.X, Spyracopoulos, L, Gagne, S.M, Liu, W, Putkey, J.A, Sykes, B.D.
Deposit date:1997-05-08
Release date:1998-05-13
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain.
J.Biol.Chem., 272, 1997
1AP4
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BU of 1ap4 by Molmil
REGULATORY DOMAIN OF HUMAN CARDIAC TROPONIN C IN THE CALCIUM-SATURATED STATE, NMR, 40 STRUCTURES
Descriptor: CALCIUM ION, CARDIAC N-TROPONIN C
Authors:Li, M.X, Spyracopoulos, L, Sia, S.K, Gagne, S.M, Chandra, M, Solaro, R.J, Sykes, B.D.
Deposit date:1997-07-24
Release date:1998-07-15
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Calcium-induced structural transition in the regulatory domain of human cardiac troponin C.
Biochemistry, 36, 1997
1BO0
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BU of 1bo0 by Molmil
MONOCYTE CHEMOATTRACTANT PROTEIN-3, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: PROTEIN (MONOCYTE CHEMOATTRACTANT PROTEIN-3)
Authors:Kwon, D, Lee, D, Sykes, B.D, Kim, K.-S.
Deposit date:1998-08-10
Release date:1999-10-10
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Structural characterization of a monomeric chemokine: monocyte chemoattractant protein-3.
FEBS Lett., 395, 1996
6MV3
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BU of 6mv3 by Molmil
NMR structure of the cNTnC-cTnI chimera bound to calcium desensitizer W7
Descriptor: CALCIUM ION, N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE, Troponin C, ...
Authors:Cai, F, Hwang, P.M, Sykes, B.D.
Deposit date:2018-10-24
Release date:2018-11-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Changes Induced by the Binding of the Calcium Desensitizer W7 to Cardiac Troponin.
Biochemistry, 57, 2018
7UHA
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BU of 7uha by Molmil
NMR structure of the cNTnC-cTnI chimera bound to W6
Descriptor: CALCIUM ION, N-(5-aminopentyl)-5-chloronaphthalene-1-sulfonamide, Troponin C, ...
Authors:Cai, F, Kampourakis, T, Cockburn, K.T, Sykes, B.D.
Deposit date:2022-03-26
Release date:2022-06-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Drugging the Sarcomere, a Delicate Balance: Position of N-Terminal Charge of the Inhibitor W7.
Acs Chem.Biol., 17, 2022
1ZAC
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BU of 1zac by Molmil
N-DOMAIN OF TROPONIN C FROM CHICKEN SKELETAL MUSCLE, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: TROPONIN-C
Authors:Tsuda, S, Miura, A, Gagne, S.M, Spyracopoulos, L, Sykes, B.D.
Deposit date:1998-04-07
Release date:1998-11-11
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Low-temperature-induced structural changes in the Apo regulatory domain of skeletal muscle troponin C.
Biochemistry, 38, 1999
1TNX
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BU of 1tnx by Molmil
NMR SOLUTION STRUCTURE OF CALCIUM SATURATED SKELETAL MUSCLE TROPONIN C
Descriptor: TROPONIN C
Authors:Slupsky, C.M, Sykes, B.D.
Deposit date:1995-08-23
Release date:1995-10-15
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:NMR solution structure of calcium-saturated skeletal muscle troponin C.
Biochemistry, 34, 1995
1TNW
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BU of 1tnw by Molmil
NMR SOLUTION STRUCTURE OF CALCIUM SATURATED SKELETAL MUSCLE TROPONIN C
Descriptor: TROPONIN C
Authors:Slupsky, C.M, Sykes, B.D.
Deposit date:1995-08-23
Release date:1995-10-15
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:NMR solution structure of calcium-saturated skeletal muscle troponin C.
Biochemistry, 34, 1995
5VLN
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BU of 5vln by Molmil
NMR structure of the N-domain of troponin C bound to switch region of troponin I
Descriptor: Troponin C, slow skeletal and cardiac muscles,Troponin I, cardiac muscle
Authors:Cai, F, Hwang, P.M, Sykes, B.D.
Deposit date:2017-04-25
Release date:2017-05-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structures reveal details of small molecule binding to cardiac troponin.
J. Mol. Cell. Cardiol., 101, 2016
1AJ4
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BU of 1aj4 by Molmil
STRUCTURE OF CALCIUM-SATURATED CARDIAC TROPONIN C, NMR, 1 STRUCTURE
Descriptor: CALCIUM ION, TROPONIN C
Authors:Sia, S.K, Li, M.X, Spyracopoulos, L, Gagne, S.M, Liu, W, Putkey, J.A, Sykes, B.D.
Deposit date:1997-05-14
Release date:1998-05-20
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain.
J.Biol.Chem., 272, 1997
1A93
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BU of 1a93 by Molmil
NMR SOLUTION STRUCTURE OF THE C-MYC-MAX HETERODIMERIC LEUCINE ZIPPER, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: MAX PROTEIN, MYC PROTO-ONCOGENE PROTEIN
Authors:Lavigne, P, Crump, M.P, Gagne, S.M, Hodges, R.S, Kay, C.M, Sykes, B.D.
Deposit date:1998-04-15
Release date:1998-10-21
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Insights into the mechanism of heterodimerization from the 1H-NMR solution structure of the c-Myc-Max heterodimeric leucine zipper.
J.Mol.Biol., 281, 1998
2AFP
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BU of 2afp by Molmil
THE SOLUTION STRUCTURE OF TYPE II ANTIFREEZE PROTEIN REVEALS A NEW MEMBER OF THE LECTIN FAMILY
Descriptor: PROTEIN (SEA RAVEN TYPE II ANTIFREEZE PROTEIN)
Authors:Gronwald, W, Loewen, M.C, Lix, B, Daugulis, A.J, Sonnichsen, F.D, Davies, P.L, Sykes, B.D.
Deposit date:1998-12-14
Release date:1998-12-23
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The solution structure of type II antifreeze protein reveals a new member of the lectin family.
Biochemistry, 37, 1998
2A93
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BU of 2a93 by Molmil
NMR SOLUTION STRUCTURE OF THE C-MYC-MAX HETERODIMERIC LEUCINE ZIPPER, 40 STRUCTURES
Descriptor: C-MYC-MAX HETERODIMERIC LEUCINE ZIPPER
Authors:Lavigne, P, Crump, M.P, Gagne, S.M, Hodges, R.S, Kay, C.M, Sykes, B.D.
Deposit date:1998-06-09
Release date:1999-01-27
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Insights into the mechanism of heterodimerization from the 1H-NMR solution structure of the c-Myc-Max heterodimeric leucine zipper.
J.Mol.Biol., 281, 1998
2CTN
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BU of 2ctn by Molmil
STRUCTURE OF CALCIUM-SATURATED CARDIAC TROPONIN C, NMR, 30 STRUCTURES
Descriptor: CALCIUM ION, TROPONIN C
Authors:Sia, S.K, Li, M.X, Spyracopoulos, L, Gagne, S.M, Liu, W, Putkey, J.A, Sykes, B.D.
Deposit date:1997-05-06
Release date:1998-05-06
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain.
J.Biol.Chem., 272, 1997
2EOT
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BU of 2eot by Molmil
SOLUTION STRUCTURE OF EOTAXIN, AN ENSEMBLE OF 32 NMR SOLUTION STRUCTURES
Descriptor: EOTAXIN
Authors:Crump, M.P, Rajarathnam, K, Kim, K.-S, Clark-Lewis, I, Sykes, B.D.
Deposit date:1998-06-29
Release date:1998-11-11
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation.
J.Biol.Chem., 273, 1998
1TNP
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BU of 1tnp by Molmil
STRUCTURES OF THE APO AND CALCIUM TROPONIN-C REGULATORY DOMAINS: THE MUSCLE CONTRACTION SWITCH
Descriptor: TROPONIN-C (APO)
Authors:Gagne, S.M, Sykes, B.D.
Deposit date:1995-07-07
Release date:1995-10-15
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structures of the troponin C regulatory domains in the apo and calcium-saturated states.
Nat.Struct.Biol., 2, 1995
1TNQ
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BU of 1tnq by Molmil
STRUCTURES OF THE APO AND CALCIUM TROPONIN-C REGULATORY DOMAINS: THE MUSCLE CONTRACTION SWITCH
Descriptor: CALCIUM ION, TROPONIN-C
Authors:Gagne, S.M, Sykes, B.D.
Deposit date:1995-07-07
Release date:1995-10-15
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structures of the troponin C regulatory domains in the apo and calcium-saturated states.
Nat.Struct.Biol., 2, 1995
1Y4E
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BU of 1y4e by Molmil
NMR structure of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger
Descriptor: Sodium/hydrogen exchanger 1
Authors:Slepkov, E.R, Rainey, J.K, Li, X, Liu, Y, Lindhout, D.A, Sykes, B.D, Fliegel, L.
Deposit date:2004-11-30
Release date:2005-02-01
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structural and functional characterization of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger.
J.Biol.Chem., 280, 2005
5WCL
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BU of 5wcl by Molmil
NMR structure of the N-domain of troponin C bound to switch region of troponin I and 3-methyldiphenylamine (solvent exposed mode)
Descriptor: 3-methyl-N-phenylaniline, Troponin C, slow skeletal and cardiac muscles,Troponin I, ...
Authors:Cai, F, Hwang, P.M, Sykes, B.D.
Deposit date:2017-06-30
Release date:2017-07-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structures reveal details of small molecule binding to cardiac troponin.
J. Mol. Cell. Cardiol., 101, 2016
5W88
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BU of 5w88 by Molmil
NMR structure of the N-domain of troponin C bound to switch region of troponin I and 3-methyldiphenylamine (peptide mode)
Descriptor: 3-methyl-N-phenylaniline, Troponin C, Troponin I
Authors:Cai, F, Hwang, P.M, Sykes, B.D.
Deposit date:2017-06-21
Release date:2017-07-12
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structures reveal details of small molecule binding to cardiac troponin.
J. Mol. Cell. Cardiol., 101, 2016
1D20
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BU of 1d20 by Molmil
SOLUTION STRUCTURE OF PHAGE LAMBDA HALF-OPERATOR DNA
Descriptor: DNA (5'-D(*CP*GP*GP*TP*GP*AP*TP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*TP*CP*AP*CP*CP*G)-3')
Authors:Baleja, J.D, Sykes, B.D.
Deposit date:1990-08-01
Release date:1991-07-15
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of phage lambda half-operator DNA by use of NMR, restrained molecular dynamics, and NOE-based refinement.
Biochemistry, 29, 1990

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