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1F31
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CRYSTAL STRUCTURE OF CLOSTRIDIUM BOTULINUM NEUROTOXIN B COMPLEXED WITH A TRISACCHARIDE
Descriptor:BOTULINUM NEUROTOXIN TYPE B, O-SIALIC ACID, ALPHA D-GALACTOSE, ...
Authors:Swaminathan, S., Eswaramoorthy, S.
Deposit date:2000-05-31
Release date:2000-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B.
Nat.Struct.Biol., 7, 2000
1SE2
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STAPHYLOCOCCAL ENTEROTOXIN C2, MONOCLINIC FORM
Descriptor:STAPHYLOCOCCAL ENTEROTOXIN C2
Authors:Swaminathan, S., Sax, M.
Deposit date:1995-07-20
Release date:1996-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Residues defining V beta specificity in staphylococcal enterotoxins.
Nat.Struct.Biol., 2, 1995
1SE3
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STAPHYLOCOCCAL ENTEROTOXIN B COMPLEXED WITH GM3 TRISACCHARIDE
Descriptor:STAPHYLOCOCCAL ENTEROTOXIN B, O-SIALIC ACID, BETA-D-GALACTOSE, ...
Authors:Swaminathan, S., Sax, M.
Deposit date:1996-10-11
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Residues defining V beta specificity in staphylococcal enterotoxins.
Nat.Struct.Biol., 2, 1995
1SE4
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STAPHYLOCOCCAL ENTEROTOXIN B COMPLEXED WITH LACTOSE
Descriptor:STAPHYLOCOCCAL ENTEROTOXIN B, BETA-LACTOSE
Authors:Swaminathan, S., Sax, M.
Deposit date:1997-04-16
Release date:1997-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Residues defining V beta specificity in staphylococcal enterotoxins.
Nat.Struct.Biol., 2, 1995
5XVK
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CRYSTAL STRUCTURE OF MOUSE NICOTINAMIDE N-METHYLTRANSFERASE (NNMT) BOUND WITH END PRODUCT, 1-METHYL NICOTINAMIDE (MNA)
Descriptor:Nicotinamide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 3-carbamoyl-1-methylpyridin-1-ium, ...
Authors:Swaminathan, S., Birudukota, S., Thakur, M.K., Parveen, R., Kandan, S., Kannt, A., Gosu, R.
Deposit date:2017-06-28
Release date:2017-08-02
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide
Biochem. Biophys. Res. Commun., 491, 2017
1EPW
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CRYSTAL STRUCTURE OF CLOSTRIDIUM NEUROTOXIN TYPE B
Descriptor:BOTULINUM NEUROTOXIN TYPE B, ZINC ION, SULFATE ION
Authors:Swaminathan, S., Eswaramoorthy, S.
Deposit date:2000-03-29
Release date:2000-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B.
Nat.Struct.Biol., 7, 2000
5YXZ
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CO-CRYSTAL STRUCTURE OF KRAS (G12C) COVALENTLY BOUND WITH QUINAZOLINE BASED INHIBITOR JBI484
Descriptor:GTPase KRas, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Swaminathan, S., Thakur, M.K., Kandan, S., Gautam, A., Kanavalli, M., Simhadri, P., Gosu, R.
Deposit date:2017-12-07
Release date:2018-04-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Co-crystal Structure of KRAS (G12C) covalently bound with Quinazoline based inhibitor JBI484
To Be Published
5YY1
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CO-CRYSTAL STRUCTURE OF KRAS (G12C) COVALENTLY BOUND WITH QUINAZOLINE BASED INHIBITOR JBI739
Descriptor:GTPase KRas, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Swaminathan, S., Thakur, M.K., Kandan, S., Gautam, A., Kanavalli, M., Simhadri, P., Gosu, R.
Deposit date:2017-12-07
Release date:2018-04-18
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Co-crystal Structure of KRAS (G12C) covalently bound with Quinazoline based inhibitor JBI739
To Be Published
1I4X
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STAPHYLOCOCCAL ENTEROTOXIN C2, MONOCLINIC FORM CRYSTALLIZED AT PH 8.0
Descriptor:ENTEROTOXIN TYPE C-2, ZINC ION
Authors:Swaminathan, S., Sax, M.
Deposit date:2001-02-23
Release date:2001-03-14
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of staphylococcal enterotoxin C2 at various pH levels.
Acta Crystallogr.,Sect.D, 57, 2001
5XVQ
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CRYSTAL STRUCTURE OF MONKEY NICOTINAMIDE N-METHYLTRANSFERASE (NNMT) BOUND WITH END PRODUCT, 1-METHYL NICOTINAMIDE (MNA)
Descriptor:Nicotinamide N-methyltransferase (NNMT), S-ADENOSYL-L-HOMOCYSTEINE, 1-methylpyridine-3-carboxamide, ...
Authors:Birudukota, S., Swaminathan, S., Thakur, M.K., Parveen, R., Kandan, S., Kannt, A., Gosu, R.
Deposit date:2017-06-28
Release date:2017-08-02
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Crystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide
Biochem. Biophys. Res. Commun., 491, 2017
5YJF
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CO-CRYSTAL STRUCTURE OF HUMAN NICOTINAMIDE N-METHYLTRANSFERASE (NNMT) WITH SMALL MOLECULE ANALOG OF NICOTINAMIDE
Descriptor:Nicotinamide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 6-methoxy-1-methyl-2H-pyridine-3-carboxamide
Authors:Swaminathan, S., Birudukota, S., Thakur, M.K., Parveen, R., Kandan, S., Hallur, M.S., Rajagopal, S., Ruf, S., Dhakshinamoorthy, S., Kannt, A., Gosu, R.
Deposit date:2017-10-10
Release date:2018-03-21
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders.
Sci Rep, 8, 2018
1B54
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CRYSTAL STRUCTURE OF A YEAST HYPOTHETICAL PROTEIN-A STRUCTURE FROM BNL'S HUMAN PROTEOME PROJECT
Descriptor:YEAST HYPOTHETICAL PROTEIN, PYRIDOXAL-5'-PHOSPHATE
Authors:Swaminathan, S., Eswaramoorthy, S., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:1999-01-12
Release date:1999-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of a yeast hypothetical protein selected by a structural genomics approach.
Acta Crystallogr.,Sect.D, 59, 2003
2ETF
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CRYSTAL STRUCTURE OF FULL LENGTH BOTULINUM NEUROTOXIN (TYPE B) LIGHT CHAIN
Descriptor:Botulinum neurotoxin B light chain, ZINC ION, SULFATE ION
Authors:Swaminathan, S., Eswaramoorthy, S.
Deposit date:2005-10-27
Release date:2005-12-06
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Crystal structure of full length botulinum neurotoxin (Type B) light chain
To be Published
2EUI
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CRYSTAL STRUCTURE OF A PROBABLE ACETYLTRANSFERASE
Descriptor:Probable acetyltransferase
Authors:Swaminathan, S., Eswaramoorthy, S., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-10-28
Release date:2005-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a probable acetyltransferase
To be Published
1G9A
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CRYSTAL STRUCTURE OF CLOSTRIDIUM BOTULINUM NEUROTOXIN B COMPLEXED WITH AN INHIBITOR (EXPERIMENT 3)
Descriptor:BOTULINUM NEUROTOXIN TYPE B, ZINC ION, BIS(5-AMIDINO-BENZIMIDAZOLYL)METHANE
Authors:Eswaramoorthy, S., Swaminathan, S.
Deposit date:2000-11-22
Release date:2002-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Novel Mechanism for Clostridium botulinum Neurotoxin Inhibition
BIOCHEMISTRY, 41, 2002
1G9B
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CRYSTAL STRUCTURE OF CLOSTRIDIUM BOTULINUM NEUROTOXIN B COMPLEXED WITH AN INHIBITOR (EXPERIMENT 1)
Descriptor:BOTULINUM NEUROTOXIN TYPE B, ZINC ION, BIS(5-AMIDINO-BENZIMIDAZOLYL)METHANE
Authors:Eswaramoorthy, S., Swaminathan, S.
Deposit date:2000-11-22
Release date:2002-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Novel Mechanism for Clostridium botulinum Neurotoxin Inhibition
BIOCHEMISTRY, 41, 2002
1G9C
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CRYSTAL STRUCTURE OF CLOSTRIDIUM BOTULINUM NEUROTOXIN B COMPLEXED WITH AN INHIBITOR (EXPERIMENT 4)
Descriptor:BOTULINUM NEUROTOXIN TYPE B, ZINC ION, BIS(5-AMIDINO-BENZIMIDAZOLYL)METHANE
Authors:Eswaramoorthy, S., Swaminathan, S.
Deposit date:2000-11-22
Release date:2002-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A Novel Mechanism for Clostridium botulinum Neurotoxin Inhibition
BIOCHEMISTRY, 41, 2002
1G9D
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CRYSTAL STRUCTURE OF CLOSTRIDIUM BOTULINUM NEUROTOXIN B COMPLEXED WITH AN INHIBITOR (EXPERIMENT 2)
Descriptor:BOTULINUM NEUROTOXIN TYPE B, ZINC ION, BIS(5-AMIDINO-BENZIMIDAZOLYL)METHANE
Authors:Eswaramoorthy, S., Swaminathan, S.
Deposit date:2000-11-22
Release date:2002-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Novel Mechanism for Clostridium botulinum Neurotoxin Inhibition
BIOCHEMISTRY, 41, 2002
1I1E
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CRYSTAL STRUCTURE OF CLOSTRIDIUM BOTULINUM NEUROTOXIN B COMPLEXED WITH DOXORUBICIN
Descriptor:BOTULINUM NEUROTOXIN TYPE B, DOXORUBICIN, ZINC ION, ...
Authors:Eswaramoorthy, S., Kumaran, D., Swaminathan, S.
Deposit date:2001-02-01
Release date:2001-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic evidence for doxorubicin binding to the receptor-binding site in Clostridium botulinum neurotoxin B.
Acta Crystallogr.,Sect.D, 57, 2001
1CQV
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CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN C2 AT 100K CRYSTALLIZED AT PH 5.0
Descriptor:PROTEIN (STAPHYLOCOCCAL ENTEROTOXIN C2), ZINC ION
Authors:Kumaran, D., Swaminathan, S.
Deposit date:1999-08-11
Release date:1999-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structure of staphylococcal enterotoxin C2 at various pH levels.
Acta Crystallogr.,Sect.D, 57, 2001
1I4P
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CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN C2 AT 100K CRYSTALLIZED AT PH 5.5
Descriptor:ENTEROTOXIN TYPE C-2, ZINC ION
Authors:Kumaran, D., Swaminathan, S.
Deposit date:2001-02-22
Release date:2001-03-14
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of staphylococcal enterotoxin C2 at various pH levels.
Acta Crystallogr.,Sect.D, 57, 2001
1I4Q
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CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN C2 AT 100K CRYSTALLIZED AT PH 6.0
Descriptor:ENTEROTOXIN TYPE C-2, ZINC ION
Authors:Kumaran, D., Swaminathan, S.
Deposit date:2001-02-22
Release date:2001-03-14
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of staphylococcal enterotoxin C2 at various pH levels.
Acta Crystallogr.,Sect.D, 57, 2001
1I4R
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CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN C2 AT 100K CRYSTALLIZED AT PH 6.5
Descriptor:ENTEROTOXIN TYPE C-2, ZINC ION
Authors:Kumaran, D., Swaminathan, S.
Deposit date:2001-02-22
Release date:2001-03-14
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of staphylococcal enterotoxin C2 at various pH levels.
Acta Crystallogr.,Sect.D, 57, 2001
1CCD
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REFINED STRUCTURE OF RAT CLARA CELL 17 KDA PROTEIN AT 3.0 ANGSTROMS RESOLUTION
Descriptor:CLARA CELL 17 kD PROTEIN, SULFATE ION
Authors:Umland, T.C., Swaminathan, S., Furey, W., Singh, G., Pletcher, J., Sax, M.
Deposit date:1991-09-17
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Refined structure of rat Clara cell 17 kDa protein at 3.0 A resolution.
J.Mol.Biol., 224, 1992
1AF9
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TETANUS NEUROTOXIN C FRAGMENT
Descriptor:TETANUS NEUROTOXIN
Authors:Umland, T.C., Wingert, L., Swaminathan, S., Furey, W.F., Schmidt, J.J., Sax, M.
Deposit date:1997-03-24
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the receptor binding fragment HC of tetanus neurotoxin.
Nat.Struct.Biol., 4, 1997