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7MJP
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BU of 7mjp by Molmil
Vascular KATP channel: Kir6.1 SUR2B propeller-like conformation 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Sung, M.W, Shyng, S.L.
Deposit date:2021-04-20
Release date:2021-10-13
Last modified:2022-10-26
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Vascular K ATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MJQ
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BU of 7mjq by Molmil
Vascular KATP channel: Kir6.1 SUR2B quatrefoil-like conformation 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ATP-sensitive inward rectifier potassium channel 8, ...
Authors:Sung, M.W, Shyng, S.L.
Deposit date:2021-04-20
Release date:2021-10-13
Last modified:2022-10-26
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Vascular K ATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MJO
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BU of 7mjo by Molmil
Vascular KATP channel: Kir6.1 SUR2B quatrefoil-like conformation 1
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ...
Authors:Sung, M.W, Shyng, S.L.
Deposit date:2021-04-20
Release date:2021-10-13
Last modified:2022-10-26
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Vascular K ATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MIT
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BU of 7mit by Molmil
Vascular KATP channel: Kir6.1 SUR2B propeller-like conformation 1
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ...
Authors:Sung, M.W, Shyng, S.L.
Deposit date:2021-04-17
Release date:2021-10-13
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Vascular K ATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides.
Proc.Natl.Acad.Sci.USA, 118, 2021
3NGL
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BU of 3ngl by Molmil
Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum
Descriptor: Bifunctional protein folD, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sung, M.W, Lee, W.H, Hwang, K.Y.
Deposit date:2010-06-12
Release date:2011-04-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase from Thermoplasma acidophilum
Biochem.Biophys.Res.Commun., 406, 2011
7U1E
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BU of 7u1e by Molmil
CryoEM structure of the pancreatic ATP-sensitive potassium channel bound to ATP with Kir6.2-CTD in the down conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
Authors:Shyng, S.L, Sung, M.W, Driggers, C.M.
Deposit date:2022-02-21
Release date:2022-08-31
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (4.52 Å)
Cite:Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
7U2X
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BU of 7u2x by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the down conformation
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Shyng, S.L, Sung, M.W, Driggers, C.M.
Deposit date:2022-02-25
Release date:2022-08-31
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
7TYS
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BU of 7tys by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with Kir6.2-CTD in the up conformation
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (9R,12R)-15-amino-12-hydroxy-6,12-dioxo-7,11,13-trioxa-12lambda~5~-phosphapentadecan-9-yl undecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Shyng, S.L, Sung, M.W, Driggers, C.M.
Deposit date:2022-02-14
Release date:2022-08-31
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
7U6Y
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BU of 7u6y by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of glibenclamide and ATP with Kir6.2-CTD in the down conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11
Authors:Shyng, S.L, Sung, M.W, Driggers, C.M.
Deposit date:2022-03-06
Release date:2022-08-31
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
7TYT
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BU of 7tyt by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with Kir6.2-CTD in the down conformation
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Shyng, S.L, Sung, M.W, Driggers, C.M.
Deposit date:2022-02-14
Release date:2022-08-31
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
7U1S
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BU of 7u1s by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with SUR1-out conformation
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Shyng, S.L, Sung, M.W, Driggers, C.M.
Deposit date:2022-02-22
Release date:2022-08-31
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
7U1Q
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BU of 7u1q by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with SUR1-in conformation
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Shyng, S.L, Sung, M.W, Driggers, C.M.
Deposit date:2022-02-21
Release date:2022-08-31
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
7U24
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BU of 7u24 by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and glibenclamide with Kir6.2-CTD in the up conformation
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ...
Authors:Shyng, S.L, Sung, M.W, Driggers, C.M.
Deposit date:2022-02-23
Release date:2022-08-31
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
7U7M
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BU of 7u7m by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the up conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11
Authors:Shyng, S.L, Sung, M.W, Driggers, C.M.
Deposit date:2022-03-07
Release date:2022-08-31
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
7UAA
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BU of 7uaa by Molmil
CryoEM structure of the pancreatic ATP-sensitive potassium channel in the ATP-bound state with Kir6.2-CTD in the up conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11
Authors:Shyng, S.L, Sung, M.W, Driggers, C.M.
Deposit date:2022-03-11
Release date:2022-08-31
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
7UQR
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BU of 7uqr by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the apo form with Kir6.2-CTD in the down conformation
Descriptor: ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11
Authors:Shyng, S.L, Sung, M.W, Driggers, C.M.
Deposit date:2022-04-20
Release date:2022-08-31
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (4.55 Å)
Cite:Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022
3E6E
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BU of 3e6e by Molmil
Crystal structure of Alanine racemase from E.faecalis complex with cycloserine
Descriptor: Alanine racemase, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE
Authors:Hwang, K.Y, Priyadarshi, A, Lee, E.H, Sung, M.W.
Deposit date:2008-08-15
Release date:2009-08-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into the alanine racemase from Enterococcus faecalis.
Biochim.Biophys.Acta, 1794, 2009
3E5P
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BU of 3e5p by Molmil
Crystal structure of alanine racemase from E.faecalis
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Alanine racemase, NONAETHYLENE GLYCOL, ...
Authors:Hwang, K.Y, Priyadarshi, A, Lee, E.H, Sung, M.W.
Deposit date:2008-08-14
Release date:2009-08-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into the alanine racemase from Enterococcus faecalis.
Biochim.Biophys.Acta, 1794, 2009
3NGX
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BU of 3ngx by Molmil
Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum
Descriptor: Bifunctional protein folD
Authors:Hwang, K.W, Sung, M.W, Lee, W.H.
Deposit date:2010-06-14
Release date:2011-04-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase from Thermoplasma acidophilum
Biochem.Biophys.Res.Commun., 406, 2011
6PZB
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BU of 6pzb by Molmil
Cryo-EM structure of the pancreatic beta-cell SUR1 Apo state
Descriptor: ATP-binding cassette sub-family C member 8
Authors:Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
Deposit date:2019-07-31
Release date:2019-08-14
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (4.55 Å)
Cite:Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
6PZI
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BU of 6pzi by Molmil
Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP only
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8
Authors:Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
Deposit date:2019-07-31
Release date:2019-08-14
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
6PZA
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BU of 6pza by Molmil
Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and glibenclamide
Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
Authors:Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
Deposit date:2019-07-31
Release date:2019-08-14
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
6PZ9
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BU of 6pz9 by Molmil
Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11, ...
Authors:Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
Deposit date:2019-07-31
Release date:2019-08-14
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
6PZC
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BU of 6pzc by Molmil
Cryo-EM structure of the pancreatic beta-cell SUR1 bound to carbamazepine
Descriptor: ATP-binding cassette sub-family C member 8
Authors:Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
Deposit date:2019-07-31
Release date:2019-08-14
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.34 Å)
Cite:Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
3KKL
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BU of 3kkl by Molmil
Crystal structure of functionally unknown HSP33 from Saccharomyces cerevisiae
Descriptor: Probable chaperone protein HSP33
Authors:Hwang, K.Y, Sung, M.W, Lee, W.H.
Deposit date:2009-11-05
Release date:2010-03-31
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystal structure of functionally unknown HSP33 from Saccharomyces cerevisiae
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