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1D7A
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CRYSTAL STRUCTURE OF E. COLI PURE-MONONUCLEOTIDE COMPLEX.
Descriptor:PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE, 5-AMINOIMIDAZOLE RIBONUCLEOTIDE
Authors:Mathews, I.I., Kappock, T.J., Stubbe, J., Ealick, S.E.
Deposit date:1999-10-16
Release date:1999-12-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of Escherichia coli PurE, an unusual mutase in the purine biosynthetic pathway.
Structure Fold.Des., 7, 1999
2ATE
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STRUCTURE OF THE COMPLEX OF PURE WITH NITROAIR
Descriptor:Phosphoribosylaminoimidazole carboxylase catalytic subunit, ((2R,3S,4R,5R)-5-(5-AMINO-4-NITRO-1H-IMIDAZOL-1-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHYL DIHYDROGEN PHOSPHATE
Authors:Kappock, T.J., Mathews, I.I., Zaugg, J.B., Peng, P., Hoskins, A.A., Okamoto, A., Ealick, S.E., Stubbe, J.
Deposit date:2005-08-24
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:N5-CAIR mutase: role of a CO2 binding site and substrate movement in catalysis.
Biochemistry, 46, 2007
1G5K
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NMR STRUCTRURE OF D(CCAAAGXACTGGG), X IS A 3'-PHOSPHOGLYCOLATE, 5'-PHOSPHATE GAPPED LESION, 10 STRUCTURES
Descriptor:5'-D(*CP*CP*AP*AP*AP*G)-3', 5'-D(P*AP*CP*TP*GP*GP*G)-3', 5'-D(*CP*CP*CP*AP*GP*TP*AP*CP*TP*TP*TP*GP*G)-3', ...
Authors:Junker, H.-D., Hoehn, S.T., Bunt, R.C., Marathius, V., Chen, J., Turner, C.J., Stubbe, J.
Deposit date:2002-10-14
Release date:2003-01-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Synthesis, Characterization and Solution Structure of Tethered Oligonucleotides Containing an Internal 3'-Phosphoglycolate, 5'-Phosphate Gapped Lesion
Nucleic Acids Res., 30, 2002
1GJ1
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NMR STRUCTURE OF D(CCAAAGXACTGGG), X IS A 3'PHOSPHOGLYCOLATE, 5'PHOSPHATE GAPPED LESION
Descriptor:5'-D(*CP*CP*AP*AP*AP*G)-3', 5'-D(P*AP*CP*TP*GP*GP*G)-3', 5'-D(*CP*CP*CP*AP*GP*TP*AP*CP*TP*TP*TP*GP*G)-3', ...
Authors:Junker, H.-D., Hoehn, S.T., Bunt, R.C., Marathius, V., Chen, J., Turner, C.J., Stubbe, J.
Deposit date:2002-10-14
Release date:2003-01-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Synthesis, Characterization and Solution Structure of Tethered Oligonucleotides Containing an Internal 3'-Phosphoglycolate, 5'-Phosphate Gapped Lesion
Nucleic Acids Res., 30, 2002
1JK0
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RIBONUCLEOTIDE REDUCTASE Y2Y4 HETERODIMER
Descriptor:ribonucleoside-diphosphate reductase small chain 1, ribonucleoside-diphosphate reductase small chain 2, ZINC ION
Authors:Voegtli, W.C., Perlstein, D.L., Ge, J., Stubbe, J., Rosenzweig, A.C.
Deposit date:2001-07-10
Release date:2001-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the yeast ribonucleotide reductase Y2Y4 heterodimer.
Proc.Natl.Acad.Sci.USA, 98, 2001
1N0K
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NMR STRUCTURE OF DUPLEX DNA D(CCAAGGXCTTGGG), X IS A 3' PHOSPHOGLYCOLATE, 5'PHOSPHATE GAPPED LESION
Descriptor:5'-D(*CP*CP*AP*AP*GP*G)-3', 5'-D(P*CP*TP*TP*GP*GP*G)-3', 5'-D(*CP*CP*CP*AP*AP*GP*GP*CP*CP*TP*TP*GP*G)-3', ...
Authors:Junker, H.-D., Hoehn, S.T., Bunt, R.C., Marathius, V., Chen, J., Turner, C.J., Stubbe, J.
Deposit date:2002-10-14
Release date:2003-01-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Synthesis, Characterization and Solution Structure of Tethered Oligonucleotides Containing an Internal 3'-Phosphoglycolate, 5'-Phosphate Gapped Lesion
Nucleic Acids Res., 30, 2002
1N0O
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NMR STRUCTURE OF D(CCAAGGXCTTGGG), X IS A 3'-PHOSPHOGLYCOLATE, 5'-PHOSPHATE GAPPED LESION, 10 STRUCTURES
Descriptor:5'-D(*CP*CP*AP*AP*GP*G)-3', 5'-D(P*CP*TP*TP*GP*GP*G)-3', 5'-D(*CP*CP*CP*AP*AP*GP*GP*CP*CP*TP*TP*GP*G)-3', ...
Authors:Junker, H.-D., Hoehn, S.T., Bunt, R.C., Marathius, V., Chen, J., Turner, C.J., Stubbe, J.
Deposit date:2002-10-14
Release date:2003-01-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Synthesis, Characterization, and Solution Structure of Tethered Oligonucleotides Containing an Internal 3'-Phosphoglycolate, 5'-Phosphate Gapped Lesion
Nucleic Acids Res., 30, 2002
1SMQ
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STRUCTURE OF THE RIBONUCLEOTIDE REDUCTASE RNR2 HOMODIMER FROM SACCHAROMYCES CEREVISIAE
Descriptor:Ribonucleoside-diphosphate reductase small chain 1
Authors:Sommerhalter, M., Voegtli, W.C., Perlstein, D.L., Ge, J., Stubbe, J., Rosenzweig, A.C.
Deposit date:2004-03-09
Release date:2004-08-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of the yeast ribonucleotide reductase Rnr2 and Rnr4 homodimers.
Biochemistry, 43, 2004
1SMS
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STRUCTURE OF THE RIBONUCLEOTIDE REDUCTASE RNR4 HOMODIMER FROM SACCHAROMYCES CEREVISIAE
Descriptor:Ribonucleoside-diphosphate reductase small chain 2, MERCURY (II) ION
Authors:Sommerhalter, M., Voegtli, W.C., Perlstein, D.L., Ge, J., Stubbe, J., Rosenzweig, A.C.
Deposit date:2004-03-09
Release date:2004-08-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of the yeast ribonucleotide reductase Rnr2 and Rnr4 homodimers.
Biochemistry, 43, 2004
2HOU
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STRUCTURE ENSEMBLES OF DUPLEX DNA CONTAINING A 4'-OXIDIZED ABASIC SITE.
Descriptor:5'-D(*CP*CP*AP*AP*AP*GP*(X4A)P*AP*CP*CP*GP*GP*G)-3', 5'-D(*CP*CP*CP*GP*GP*TP*AP*CP*TP*TP*TP*GP*G)-3'
Authors:Chen, J., Dupradeau, F.Y., Case, D.A., Turner, C.J., Stubbe, J.
Deposit date:2006-07-16
Release date:2007-05-29
Last modified:2018-08-08
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance structural studies and molecular modeling of duplex DNA containing normal and 4'-oxidized abasic sites.
Biochemistry, 46, 2007
2HPX
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13MER DUPLEX DNA CONTAINING A 4'-OXIDIZED ABASIC SITE, AVERAGED STRUCTURE
Descriptor:5'-D(*CP*CP*AP*AP*AP*GP*(X4A)P*AP*CP*CP*GP*GP*G)-3', 5'-D(*CP*CP*CP*GP*GP*TP*AP*CP*TP*TP*TP*GP*G)-3'
Authors:Chen, J., Dupradeau, F.Y., Case, D.A., Turner, C.J., Stubbe, J.
Deposit date:2006-07-17
Release date:2007-05-29
Last modified:2018-08-08
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance structural studies and molecular modeling of duplex DNA containing normal and 4'-oxidized abasic sites.
Biochemistry, 46, 2007
2HSK
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NMR STRUCTURE OF 13MER DUPLEX DNA CONTAINING AN ABASIC SITE (Y) IN 5'-CCAAAGYACCGGG-3' (10 STRUCTURES, ALPHA ANOMER)
Descriptor:5'-D(*CP*CP*AP*AP*AP*GP*(D1P)P*AP*CP*CP*GP*GP*G)-3', 5'-D(*CP*CP*CP*GP*GP*TP*AP*CP*TP*TP*TP*GP*G)-3'
Authors:Chen, J., Dupradeau, F.Y., Case, D.A., Turner, C.J., Stubbe, J.
Deposit date:2006-07-21
Release date:2007-05-29
Last modified:2018-08-08
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance structural studies and molecular modeling of duplex DNA containing normal and 4'-oxidized abasic sites.
Biochemistry, 46, 2007
2HSL
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NMR STRUCTURE OF 13MER DUPLEX DNA CONTAINING AN ABASIC SITE, AVERAGED STRUCTURE (ALPHA ANOMER)
Descriptor:5'-D(*CP*CP*AP*AP*AP*GP*(D1P)P*AP*CP*CP*GP*GP*G)-3', 5'-D(*CP*CP*CP*GP*GP*TP*AP*CP*TP*TP*TP*GP*G)-3'
Authors:Chen, J., Dupradeau, F.Y., Case, D.A., Turner, C.J., Stubbe, J.
Deposit date:2006-07-22
Release date:2007-05-29
Last modified:2018-08-08
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance structural studies and molecular modeling of duplex DNA containing normal and 4'-oxidized abasic sites.
Biochemistry, 46, 2007
2HSR
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13MER DUPLEX DNA CONTAINING AN ABASIC SITE WITH BETA ANOMER
Descriptor:5'-D(*CP*CP*AP*AP*AP*GP*(AAB)P*AP*CP*CP*GP*GP*G)-3', 5'-D(*CP*CP*CP*GP*GP*TP*AP*CP*TP*TP*TP*GP*G)-3'
Authors:Chen, J., Dupradeau, F.Y., Case, D.A., Turner, C.J., Stubbe, J.
Deposit date:2006-07-22
Release date:2007-05-29
Last modified:2018-08-08
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance structural studies and molecular modeling of duplex DNA containing normal and 4'-oxidized abasic sites.
Biochemistry, 46, 2007
2HSS
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13MER DUPLEX DNA CONTAING AN ABASIC SITE WITH BETA ANOMER, AVERAGED STRUCTURE
Descriptor:5'-D(*CP*CP*AP*AP*AP*GP*(AAB)P*AP*CP*CP*GP*GP*G)-3', 5'-D(*CP*CP*CP*GP*GP*TP*AP*CP*TP*TP*TP*GP*G)-3'
Authors:Chen, J., Dupradeau, F.Y., Case, D.A., Turner, C.J., Stubbe, J.
Deposit date:2006-07-22
Release date:2007-05-29
Last modified:2018-08-08
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance structural studies and molecular modeling of duplex DNA containing normal and 4'-oxidized abasic sites.
Biochemistry, 46, 2007
2O7W
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DUPLEX DNA CONTAINING AN ABASIC SITE WITH AN OPPOSITE G (ALPHA ANOMER) IN 5'-G_AC-3' (10 STRUCTURE ENSEMBLE AND AVERAGED STRUCTURE)
Descriptor:5'-D(*CP*CP*AP*AP*AP*GP*(ORP)P*AP*CP*CP*GP*GP*G)-3', 5'-D(*CP*CP*CP*GP*GP*TP*GP*CP*TP*TP*TP*GP*G)-3'
Authors:Chen, J., Dupradeau, F.Y., Case, D.A., Turner, C.J., Stubbe, J.
Deposit date:2006-12-11
Release date:2007-11-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:DNA oligonucleotides with A, T, G or C opposite an abasic site: structure and dynamics.
Nucleic Acids Res., 36, 2008
2O7X
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DUPLEX DNA CONTAINING AN ABASIC SITE WITH AN OPPOSITE G (BETA ANOMER) IN 5'-G_AC-3' (10 STRUCTURE ENSEMBLE AND AVERAGED STRUCTURE)
Descriptor:5'-D(*CP*CP*AP*AP*AP*GP*(AAB)P*AP*CP*CP*GP*GP*G)-3', 5'-D(*CP*CP*CP*GP*GP*TP*GP*CP*TP*TP*TP*GP*G)-3'
Authors:Chen, J., Dupradeau, F.Y., Case, D.A., Turner, C.J., Stubbe, J.
Deposit date:2006-12-11
Release date:2007-11-27
Last modified:2014-07-09
Method:SOLUTION NMR
Cite:DNA oligonucleotides with A, T, G or C opposite an abasic site: structure and dynamics.
Nucleic Acids Res., 36, 2008
2O7Z
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DUPLEX DNA CONTAINING AN ABASIC SITE WITH AN OPPOSITE T (BETA ANOMER) IN 5'-G_AC-3' (10 STRUCTURE ENSEMBLE AND AVERAGED STRUCTURE)
Descriptor:5'-D(*CP*CP*AP*AP*AP*GP*(AAB)P*AP*CP*CP*GP*GP*G)-3', 5'-D(*CP*CP*CP*GP*GP*TP*TP*CP*TP*TP*TP*GP*G)-3'
Authors:Chen, J., Dupradeau, F.Y., Case, D.A., Turner, C.J., Stubbe, J.
Deposit date:2006-12-11
Release date:2007-11-27
Last modified:2014-07-09
Method:SOLUTION NMR
Cite:DNA oligonucleotides with A, T, G or C opposite an abasic site: structure and dynamics.
Nucleic Acids Res., 36, 2008
2O80
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DUPLEX DNA CONTAINING AN ABASIC SITE WITH AN OPPOSITE DC (ALPHA ANOMER) IN 5'-G_AC-3' (10 STRUCTURE ENSEMBLE AND AVERAGED STRUCTURE)
Descriptor:5'-D(*CP*CP*AP*AP*AP*GP*(ORP)P*AP*CP*CP*GP*GP*G)-3', 5'-D(*CP*CP*CP*GP*GP*TP*CP*CP*TP*TP*TP*GP*G)-3'
Authors:Chen, J., Dupradeau, F.Y., Case, D.A., Turner, C.J., Stubbe, J.
Deposit date:2006-12-11
Release date:2007-11-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:DNA oligonucleotides with A, T, G or C opposite an abasic site: structure and dynamics.
Nucleic Acids Res., 36, 2008
2O82
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DUPLEX DNA CONTAINING AN ABASIC SITE WITH AN OPPOSITE DC (BETA ANOMER) IN 5'-G_AC-3' (10 STRUCTURE ENSEMBLE AND AVERAGED STRUCTURE)
Descriptor:5'-D(*CP*CP*AP*AP*AP*GP*(AAB)P*AP*CP*CP*GP*GP*G)-3', 5'-D(*CP*CP*CP*GP*GP*TP*CP*CP*TP*TP*TP*GP*G)-3'
Authors:Chen, J., Dupradeau, F.Y., Case, D.A., Turner, C.J., Stubbe, J.
Deposit date:2006-12-11
Release date:2007-11-27
Last modified:2014-07-09
Method:SOLUTION NMR
Cite:DNA oligonucleotides with A, T, G or C opposite an abasic site: structure and dynamics.
Nucleic Acids Res., 36, 2008
2O7Y
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DUPLEX DNA CONTAINING AN ABASIC SITE WITH AN OPPOSITE T (ALPHA ANOMER) IN 5'-G_AC-3' (10 STRUCTURE ENSEMBLE AND AVERAGED STRUCTURE)
Descriptor:5'-D(*CP*CP*AP*AP*AP*GP*(ORP)P*AP*CP*CP*GP*GP*G)-3', 5'-D(*CP*CP*CP*GP*GP*TP*TP*CP*TP*TP*TP*GP*G)-3'
Authors:Dupradeau, F.Y., Case, D.A., Turner, C.J., Stubbe, J.
Deposit date:2006-12-11
Release date:2007-11-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:DNA oligonucleotides with A, T, G or C opposite an abasic site: structure and dynamics.
Nucleic Acids Res., 36, 2008
5D1Y
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LOW RESOLUTION CRYSTAL STRUCTURE OF HUMAN RIBONUCLEOTIDE REDUCTASE ALPHA6 HEXAMER IN COMPLEX WITH DATP
Descriptor:Ribonucleoside-diphosphate reductase large subunit
Authors:Ando, N., Li, H., Brignole, E.J., Thompson, S., McLaughlin, M.I., Page, J., Asturias, F., Stubbe, J., Drennan, C.L.
Deposit date:2015-08-04
Release date:2016-01-20
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (9.005 Å)
Cite:Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer.
Biochemistry, 55, 2016
1B6R
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N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE FROM E. COLI
Descriptor:PROTEIN (N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE), SULFATE ION
Authors:Thoden, J.B., Kappock, T.J., Stubbe, J., Holden, H.M.
Deposit date:1999-01-17
Release date:1999-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Three-dimensional structure of N5-carboxyaminoimidazole ribonucleotide synthetase: a member of the ATP grasp protein superfamily.
Biochemistry, 38, 1999
1B6S
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STRUCTURE OF N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE
Descriptor:PROTEIN (N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE), MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Thoden, J.B., Kappock, T.J., Stubbe, J., Holden, H.M.
Deposit date:1999-01-18
Release date:1999-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structure of N5-carboxyaminoimidazole ribonucleotide synthetase: a member of the ATP grasp protein superfamily.
Biochemistry, 38, 1999
1CLI
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X-RAY CRYSTAL STRUCTURE OF AMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE (PURM), FROM THE E. COLI PURINE BIOSYNTHETIC PATHWAY, AT 2.5 A RESOLUTION
Descriptor:PROTEIN (PHOSPHORIBOSYL-AMINOIMIDAZOLE SYNTHETASE), SULFATE ION
Authors:Li, C., Kappock, T.J., Stubbe, J., Weaver, T.M., Ealick, S.E.
Deposit date:1999-04-28
Release date:1999-10-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray crystal structure of aminoimidazole ribonucleotide synthetase (PurM), from the Escherichia coli purine biosynthetic pathway at 2.5 A resolution.
Structure Fold.Des., 7, 1999