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6CCY
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CRYSTAL STRUCTURE OF AKT1 IN COMPLEX WITH A SELECTIVE INHIBITOR
Descriptor:RAC-alpha serine/threonine-protein kinase,PIFtide, (5R)-4-(4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[2-(pyrrolidin-1-yl)ethyl]-1H-imidazol-2-yl}piperidin-1-yl)-5-methyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one
Authors:Wang, Y., Stout, S.
Deposit date:2018-02-07
Release date:2018-05-02
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Discovery of chiral dihydropyridopyrimidinones as potent, selective and orally bioavailable inhibitors of AKT.
Bioorg. Med. Chem. Lett., 28, 2018
1ZCT
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STRUCTURE OF GLYCOGENIN TRUNCATED AT RESIDUE 270 IN A COMPLEX WITH UDP
Descriptor:Glycogenin-1, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE
Authors:Hurley, T.D., Stout, S.L., Miner, E., Zhou, J., Roach, P.J.
Deposit date:2005-04-13
Release date:2005-04-26
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Requirements for catalysis in mammalian glycogenin.
J.Biol.Chem., 280, 2005
1ZCU
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APO FORM OF THE 162S MUTANT OF GLYCOGENIN
Descriptor:Glycogenin-1
Authors:Hurley, T.D., Stout, S.L., Miner, E., Zhou, J., Roach, P.J.
Deposit date:2005-04-13
Release date:2005-04-26
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Requirements for catalysis in mammalian glycogenin.
J.Biol.Chem., 280, 2005
1ZCV
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APO FORM OF A MUTANT OF GLYCOGENIN IN WHICH ASP159 IS REPLACED BY ASN
Descriptor:Glycogenin-1, SULFATE ION
Authors:Hurley, T.D., Stout, S.L., Miner, E., Zhou, J., Roach, P.J.
Deposit date:2005-04-13
Release date:2005-04-26
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Requirements for catalysis in mammalian glycogenin.
J.Biol.Chem., 280, 2005
1ZCY
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APO FORM OF A MUTANT OF GLYCOGENIN IN WHICH ASP159 IS REPLACED BY SER
Descriptor:Glycogenin-1, SULFATE ION
Authors:Hurley, T.D., Stout, S.L., Miner, E., Zhou, J., Roach, P.J.
Deposit date:2005-04-13
Release date:2005-04-26
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Requirements for catalysis in mammalian glycogenin.
J.Biol.Chem., 280, 2005
1ZDF
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SER162 MUTANT OF GLYCOGENIN COMPLEXED WITH UDP-GLUCOSE AND MANGANESE
Descriptor:Glycogenin-1, MANGANESE (II) ION, SULFATE ION, ...
Authors:Hurley, T.D., Stout, S.L., Miner, E., Zhou, J., Roach, P.J.
Deposit date:2005-04-14
Release date:2005-04-26
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Requirements for catalysis in mammalian glycogenin.
J.Biol.Chem., 280, 2005
1ZDG
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SER159 MUTANT OF GLYCOGENIN COMPLEXED WITH UDP-GLUCOSE AND MANGANESE
Descriptor:Glycogenin-1, MANGANESE (II) ION, SULFATE ION, ...
Authors:Hurley, T.D., Stout, S.L., Miner, E., Zhou, J., Roach, P.J.
Deposit date:2005-04-14
Release date:2005-04-26
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Requirements for catalysis in mammalian glycogenin.
J.Biol.Chem., 280, 2005